专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

51. 发明授权

US09393310B2 Drug loaded polymeric nanoparticles and methods of making and using same 有权
公开(公告)号：US09393310B2
公开(公告)日：2016-07-19
申请号：US13478691
申请日：2012-05-23
申请人： Stephen E. Zale , Greg Troiano , Mir Mukkaram Ali , Jeff Hrkach , James Wright
发明人： Stephen E. Zale , Greg Troiano , Mir Mukkaram Ali , Jeff Hrkach , James Wright
IPC分类号： A61K9/14 , A61K47/34 , A61K9/10 , A61K9/19 , A61K9/51 , A61K31/337 , A61K31/436 , A61K31/475 , A61K47/48 , B82Y5/00 , A61J3/00 , A61K31/4355 , A61K31/437 , A61K31/704 , A61K31/7068 , A61K9/16 , C07C59/08
CPC分类号： A61K47/34 , A61J3/00 , A61K9/10 , A61K9/107 , A61K9/1647 , A61K9/19 , A61K9/5146 , A61K9/5153 , A61K31/337 , A61K31/4355 , A61K31/436 , A61K31/437 , A61K31/439 , A61K31/475 , A61K31/704 , A61K31/7068 , A61K47/6915 , A61K47/6925 , A61K47/6937 , B82Y5/00 , C07C59/08 , Y10S977/773
摘要： The present disclosure generally relates to nanoparticles having about 0.2 to about 35 weight percent of a therapeutic agent; and about 10 to about 99 weight percent of biocompatible polymer such as a diblock poly(lactic) acid-poly(ethylene)glycol. Other aspects of the invention include methods of making such nanoparticles.

52. 发明授权

US08757924B2 Thermatic torpedo for reinstatement materials 有权
标题翻译：用于恢复材料的鱼雷鱼雷
公开(公告)号：US08757924B2
公开(公告)日：2014-06-24
申请号：US13824347
申请日：2011-10-16
申请人： James Wright
发明人： James Wright
IPC分类号： E01C19/46 , E01C19/10
CPC分类号： E01C19/1036 , E01C19/08 , E01C19/46 , E01C19/466
摘要： A thermic torpedo for preparing and delivering reinstatement materials has an internal chamber defining at least one compartment for containing graded aggregate and a second compartment for containing a stabilising agent, an external skin for insulating the contents of said internal chamber, a cap or lid for securely containing the contents of the torpedo in which is located at least one telescopic probe which can be driven through the compartments to heat and/or mix the contents thereof and at least one aperture through which the reinstatement materials may be expelled for delivery to a work site.
摘要翻译：用于制备和递送复原材料的热鱼雷具有限定至少一个隔室的内部腔室，用于容纳分级聚集体和用于容纳稳定剂的第二隔室，用于绝缘所述内部室的内容物的外部皮肤，用于安全地盖住盖子或盖子包含鱼雷的内容物，其中位于至少一个伸缩探头上，该探头可以被驱动穿过隔室以加热和/或混合其内容物和至少一个孔，复原材料可以通过该孔径排出以输送到工作地点。

53. 发明申请

US20120276162A1 Drug Loaded Polymeric Nanoparticles and Methods of Making and Using Same 有权
公开(公告)号：US20120276162A1
公开(公告)日：2012-11-01
申请号：US13478691
申请日：2012-05-23
申请人： Stephen E. Zale , Greg Troiano , Mir Mukkaram Ali , Jeff Hrkach , James Wright
发明人： Stephen E. Zale , Greg Troiano , Mir Mukkaram Ali , Jeff Hrkach , James Wright
IPC分类号： A61K47/32 , A61K31/475 , A61K9/14 , A61P35/00 , A61K31/337 , A61K31/436 , B82Y5/00
CPC分类号： A61K47/34 , A61J3/00 , A61K9/10 , A61K9/107 , A61K9/1647 , A61K9/19 , A61K9/5146 , A61K9/5153 , A61K31/337 , A61K31/4355 , A61K31/436 , A61K31/437 , A61K31/439 , A61K31/475 , A61K31/704 , A61K31/7068 , A61K47/6915 , A61K47/6925 , A61K47/6937 , B82Y5/00 , C07C59/08 , Y10S977/773
摘要： The present disclosure generally relates to nanoparticles having about 0.2 to about 35 weight percent of a therapeutic agent; and about 10 to about 99 weight percent of biocompatible polymer such as a diblock poly(lactic) acid-poly(ethylene)glycol. Other aspects of the invention include methods of making such nanoparticles.

54. 发明授权

US08211473B2 Stable formulations for lyophilizing therapeutic particles 有权
标题翻译：用于冻干治疗颗粒的稳定制剂
公开(公告)号：US08211473B2
公开(公告)日：2012-07-03
申请号：US13253443
申请日：2011-10-05
申请人： Greg Troiano , Young-Ho Song , Stephen E. Zale , James Wright , Christina Van Geen Hoven
发明人： Greg Troiano , Young-Ho Song , Stephen E. Zale , James Wright , Christina Van Geen Hoven
IPC分类号： A61K31/724 , A61K47/40 , A61K47/30 , A61K9/14 , A61K9/19
CPC分类号： A61K31/337 , A61K9/0019 , A61K9/16 , A61K9/19 , A61K9/5123 , A61K9/5153 , A61K9/5161 , A61K9/5192 , A61K31/335 , A61K47/26 , A61K47/34 , A61K47/40 , C08G63/664 , Y10S977/906
摘要： The present disclosure generally relates to lyophilized pharmaceutical compositions comprising polymeric nanoparticles which, upon reconstitution, have low levels of greater than 10 micron size particles. Other aspects of the invention include methods of making such nanoparticles.
摘要翻译：本公开一般涉及包含聚合物纳米颗粒的冻干药物组合物，其在重构时具有低水平的大于10微米尺寸的颗粒。本发明的其它方面包括制备这种纳米颗粒的方法。

55. 发明申请

US20120140790A1 Therapeutic Polymeric Nanoparticle Compositions with High Glass Transition Termperature or High Molecular Weight Copolymers 有权
标题翻译：具有高玻璃化转变温度或高分子量共聚物的聚合物纳米粒子组合物
公开(公告)号：US20120140790A1
公开(公告)日：2012-06-07
申请号：US13372036
申请日：2012-02-13
申请人： Mir M. Ali , Abhimanyu Sabnis , David Dewitt , Greg Troiano , James Wright , Maria Figueiredo , Michael Figa , Tina Van Geen Hoven , Young-Ho Song , Jason Auer , Tarikh C. Campbell
发明人： Mir M. Ali , Abhimanyu Sabnis , David Dewitt , Greg Troiano , James Wright , Maria Figueiredo , Michael Figa , Tina Van Geen Hoven , Young-Ho Song , Jason Auer , Tarikh C. Campbell
IPC分类号： G01N25/20 , G01K17/00
CPC分类号： G01N25/4866 , A61K9/0019 , A61K9/146 , A61K9/5153 , A61K31/00 , A61K31/337 , A61K31/427 , A61K31/436 , A61K31/475 , A61K31/573 , A61K31/58 , A61K31/585 , A61K31/69 , A61K47/34
摘要： The present disclosure relates in part to pharmaceutical compositions comprising polymeric nanoparticles having certain glass transition temperatures. Other aspects of the invention include methods of making such nanoparticles.
摘要翻译：本公开部分涉及包含具有某些玻璃化转变温度的聚合物纳米颗粒的药物组合物。本发明的其它方面包括制备这种纳米颗粒的方法。

56. 发明授权

US07754659B2 Reducing flow-back in well treating materials 有权
标题翻译：在井处理材料中减少回流
公开(公告)号：US07754659B2
公开(公告)日：2010-07-13
申请号：US11803688
申请日：2007-05-15
申请人： Richard Rediger , Michael J. Aron , James Wright
发明人： Richard Rediger , Michael J. Aron , James Wright
IPC分类号： C09K8/74 , E21B43/267
CPC分类号： E21B43/267 , C09K8/805
摘要： A composite proppant having a proppant substrate such as a porous ceramic or silica sand coated with magnetic particles and a method of propping a subterranean formation using a composition consisting essentially of the composite proppant.
摘要翻译：具有支撑剂底物的复合支撑剂，例如多孔陶瓷或涂有磁性颗粒的硅砂，以及使用基本上由复合支撑剂组成的组合物来支撑地层的方法。

57. 发明申请

US20100104655A1 Therapeutic Polymeric Nanoparticles Comprising Vinca Alkaloids and Methods of Making and Using Same 有权
标题翻译：包含长春花碱生物碱的治疗性聚合物纳米颗粒及其制备和使用方法
公开(公告)号：US20100104655A1
公开(公告)日：2010-04-29
申请号：US12485467
申请日：2009-06-16
申请人： Stephen E. Zale , Greg Troiano , Mir Mukkaram Ali , Jeff Hrkach , James Wright
发明人： Stephen E. Zale , Greg Troiano , Mir Mukkaram Ali , Jeff Hrkach , James Wright
IPC分类号： A61K9/14 , A61K47/34 , A61K31/55 , A61K31/4745 , A61P35/00
CPC分类号： A61K9/1647 , A61K9/14 , A61K9/1694 , A61K9/19 , A61K9/5153 , A61K31/4745 , A61K31/475 , A61K31/55 , A61K47/26
摘要： The present disclosure generally relates to therapeutic nanoparticles. Exemplary nanoparticles disclosed herein may include about 1 to about 20 weight percent of a vinca alkaloid; and about 50 to about 99 weight percent biocompatible polymer.
摘要翻译：本公开一般涉及治疗性纳米颗粒。本文公开的示例性纳米颗粒可包括约1至约20重量％的长春花生物碱; 和约50至约99重量％的生物相容性聚合物。

58. 发明申请

US20080314480A1 Martensitic Stainless Steel Strengthened By Ni3tin-Phase Precipitation 有权
标题翻译：通过Ni3tin相析出强化马氏体不锈钢
公开(公告)号：US20080314480A1
公开(公告)日：2008-12-25
申请号：US11814780
申请日：2006-01-25
申请人： James Wright , Jin-Won Jung
发明人： James Wright , Jin-Won Jung
IPC分类号： C22C38/52
CPC分类号： C22C38/004 , C21D6/004 , C21D6/007 , C21D2211/008 , C22C38/06 , C22C38/44 , C22C38/50 , C22C38/52
摘要： A precipitation-hardened stainless maraging steel which exhibits a combination of strength, toughness, and corrosion resistance comprises by weight about: 8 to 15% chromium (Cr), 2 to 15% cobalt (Co), 7 to 14% nickel (Ni), and up to about 0.7% aluminum (Al), less than about 0.4% copper (Cu), 0.5% to 2.5% molybdenum (Mo), 0.4 to 0.75% titanium (Ti), up to about 0.5% tungsten (W), and up to about 120 wppm carbon (C), the balance essentially iron (Fe) and incidental elements and impurities, characterized in that the alloy has a predominantly lath martensite microstructure essentially without topologically close packed intermetallic phases and strengthened primarily by a dispersion of intermetallic particles primarily of the eta-Ni3Ti phase and wherein the titanium and carbon (Ti) and (C) levels are controlled such that C can be dissolved during a homogenization step and subsequently precipitated during forging to provide a grain-pinning dispersion.
摘要翻译：表现出强度，韧性和耐腐蚀性的组合的沉淀硬化的不锈钢马氏体时效钢包含约8〜15％的铬（Cr），2〜15％的钴（Co），7〜14％的镍（Ni），高达约0.7％的铝（Al），小于约0.4％的铜（Cu），0.5％至2.5％的钼（Mo），0.4至0.75％的钛（Ti），至多约0.5％的钨（W），和高达约120wppm的碳（C），余量基本上为铁（Fe）和附带元素和杂质，其特征在于该合金主要具有板条马氏体组织，基本上没有拓扑密实的金属间相，并主要通过主要是eta-Ni3Ti相的金属间化合物颗粒，其中控制钛和碳（Ti）和（C）水平，使得C在均匀化步骤期间可以溶解，随后在锻造期间沉淀以提供颗粒钉扎分散体。

59. 发明申请

US20070024496A1 GPS carrier phase measurement representation and method of use 有权
标题翻译： GPS载波相位测量表示法和使用方法
公开(公告)号：US20070024496A1
公开(公告)日：2007-02-01
申请号：US11335245
申请日：2006-01-19
申请人： James Wright , William Chuba , Richard Hujsak
发明人： James Wright , William Chuba , Richard Hujsak
IPC分类号： G01S5/14
CPC分类号： G01S19/29 , G01S19/14
摘要： Sequential GPS Doppler carrier phase count measurements are used for precision sequential determination of position and velocity of a GPS receiver, such as for orbit determination and geolocation, with minimum throughput time. Real-time orbit determination and geolocation performance is enabled with an optimal sequential filter, and near-real-time performance is enabled with an optimal fixed-lag smoother. Many problems associated with prior art orbit determination are eliminated by addressing the “cycle slip” problem, the unknown initial range problem with RANGECP measurement representations, the problem of serial correlation in the measurements due to reprocessing of overlapping thermal noise. Also, the present invention significantly attenuates the carrier signal phase variation due to rotation of receiver antenna relative to transmitter antenna because the sequential phase count time intervals are sufficiently short.
摘要翻译：顺序GPS多普勒载波相位计数测量用于精确连续确定GPS接收机的位置和速度，例如用于轨道确定和地理定位，最小吞吐时间。实时轨道确定和地理定位性能可通过最优顺序滤波器实现，并且可实现近实时性能，并具有最优的固定滞后平滑器。与现有技术的轨道确定相关的许多问题通过解决“循环滑移”问题，RANGE 测量表示的未知初始范围问题，由于重叠处理引起的测量中的串行相关问题而被消除热噪声。此外，由于连续相位计数时间间隔足够短，本发明显着地衰减了由于接收机天线相对于发射机天线的转动而导致的载波信号相位变化。

60. 外观设计

USD531999S1 Telephone conferencing device 有权
公开(公告)号：USD531999S1
公开(公告)日：2006-11-14
申请号：US29227614
申请日：2005-04-13
申请人： Christopher Bourne , James Wright
设计人： Christopher Bourne , James Wright

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式