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51. 发明申请

US20050256174A1 Raf kinase inhibitors 审中-公开
标题翻译： Raf激酶抑制剂
公开(公告)号：US20050256174A1
公开(公告)日：2005-11-17
申请号：US11149332
申请日：2005-06-10
申请人： Jill Wood , Hanno Wild , Daniel Rogers , John Lyons , Michael Katz , Yolanda Caringal , Robert Dally , Wendy Lee , Roger Smith , Cheri Blum
发明人： Jill Wood , Hanno Wild , Daniel Rogers , John Lyons , Michael Katz , Yolanda Caringal , Robert Dally , Wendy Lee , Roger Smith , Cheri Blum
IPC分类号： A61K31/38 , A61K31/381 , A61K31/416 , A61K31/433 , C07D207/34 , C07D307/68 , C07D333/38 , C07D333/42 , C07D409/00 , C07D409/12 , C07D417/12
CPC分类号： C07D207/34 , C07D307/68 , C07D333/38 , C07D409/12 , C07D417/12 , C07D471/04
摘要： Methods of treating tumors mediated by raf kinase, with substituted urea compounds, and such compounds per se.
摘要翻译：治疗由raf激酶介导的肿瘤与取代的脲化合物及其化合物本身的方法。

52. 发明授权

US06913936B2 Immunological test kit comprising an immunologically invisible peg copolymer conjugated to one or more immunologically reactive substances 失效
标题翻译：免疫测试试剂盒包含与一种或多种免疫反应性物质缀合的免疫不可见的聚合物共聚物
公开(公告)号：US06913936B2
公开(公告)日：2005-07-05
申请号：US09982265
申请日：2001-10-17
申请人： Bo Qiu , Guobao Zhang , Stanley Stein , Leonard H Sigal , Michael Brunner , Michael Katz
发明人： Bo Qiu , Guobao Zhang , Stanley Stein , Leonard H Sigal , Michael Brunner , Michael Katz
IPC分类号： G01N33/543 , G01N33/545 , C07K17/06 , C07K17/08 , G01N33/546
CPC分类号： G01N33/543 , Y10S436/811 , Y10S436/823
摘要： A novel compound comprising an immunologically invisible polyethylene glycol copolymer is used to carry one or more immunologically reactive substances. The novel compounds may be used as part of kits for immunological assays.
摘要翻译：包含免疫隐性聚乙二醇共聚物的新型化合物用于携带一种或多种免疫反应性物质。新化合物可用作免疫测定试剂盒的一部分。

53. 外观设计

USD444133S1 Folding computer 失效
公开(公告)号：USD444133S1
公开(公告)日：2001-06-26
申请号：US29094616
申请日：1998-10-06
申请人： Michael Katz
设计人： Michael Katz

54. 发明授权

US5562313A Threadless connector for electrical conduits 失效
标题翻译：用于电气导管的无螺纹连接器
公开(公告)号：US5562313A
公开(公告)日：1996-10-08
申请号：US344486
申请日：1994-11-22
申请人： Alexey Piniaev , Simon Litvin , Alexander Ljubomirsky , Alexey Zakharov , Alexey Mishin , Michael Valdman , Michael Katz
发明人： Alexey Piniaev , Simon Litvin , Alexander Ljubomirsky , Alexey Zakharov , Alexey Mishin , Michael Valdman , Michael Katz
IPC分类号： F16L21/08 , F16L17/04
CPC分类号： F16L21/08
摘要： A threadless connector for cable pipes or electrical conduit that includes two half-couplings having tightening flanges along their lateral edges or faces. Female and male necks and beads extend along the cooperating lateral faces to form longitudinal seals when the half-couplings are clamped together. Internal radial grooves located near the outer parts of both ends of the half-couplings cooperate with split compression rings the outer surface of which compresses against the conic grooves and the inner edges bite into the connected pipe sections to form radial seals therewith. The half-couplings can be either two separate congruent parts or joined along one edge as desired.
摘要翻译：用于电缆管道或电气导管的无螺纹连接器，包括两个半连接件，沿其横向边缘或表面具有紧固法兰。当半联轴器夹在一起时，母和颈颈和珠沿着协作的侧面延伸以形成纵向密封。位于半联轴器两端的外部部分附近的内部径向槽与分离的压缩环配合，其分离的压缩环的外表面压缩锥形槽，并且内边缘咬入连接的管段以与其形成径向密封。半联轴器可以是两个独立的一致部件，也可以根据需要沿一个边缘连接。

55. 发明授权

US4552857A Cathode coating with hydrogen-evolution catalyst and semi-conducting polymer 失效
标题翻译：具有析氢催化剂和半导体聚合物的阴极涂层
公开(公告)号：US4552857A
公开(公告)日：1985-11-12
申请号：US365185
申请日：1982-04-05
申请人： Michael Katz , Jean Hinden , Jurgen Gauger
发明人： Michael Katz , Jean Hinden , Jurgen Gauger
IPC分类号： C25B11/04 , C25B11/06 , C25B11/10 , H01M4/88 , B05D5/12
CPC分类号： C25B11/0489
摘要： A cathode coating comprises a catalyst for hydrogen evolution finely dispersed in a matrix consisting of an insoluble, semiconducting polymer which is formed in situ on an electrode support body. A bipolar electrode is provided with such a cathode coating on a support body consisting of a valve metal such as titanium.The cathode coating is formed by applying to the electrode support body a coating solution which contains an inorganic precursor compound for the hydrogen evolution catalyst and an organic precursor compound for forming the polymer matrix, drying and then thermally converting these precursors to a cathode coating adhering to the electrode support body.
摘要翻译：阴极涂层包括精细分散在由在电极支撑体上原位形成的不溶性半导体聚合物构成的基质中的析氢催化剂。双极电极在由诸如钛的阀金属组成的支撑体上设置有这样的阴极涂层。阴极涂层通过向电极支撑体施加包含用于析氢催化剂的无机前体化合物和用于形成聚合物基质的有机前体化合物的涂布溶液形成，干燥然后将这些前体热转化成附着于电极支撑体。

56. 发明授权

US4435313A Electrode with outer coating for effecting an electrolytic process and protective intermediate coating on a conductive base, and method of making same 失效
标题翻译：具有外部涂层的电极，用于在导电性基底上进行电解处理和保护性中间涂层及其制造方法
公开(公告)号：US4435313A
公开(公告)日：1984-03-06
申请号：US293381
申请日：1981-08-17
申请人： Michael Katz , Jean M. Hinden , Jurgen F. Gauger
发明人： Michael Katz , Jean M. Hinden , Jurgen F. Gauger
IPC分类号： C25B11/04 , C25B11/08 , C25B11/10 , C25B11/16 , C25C7/02
CPC分类号： C25B11/16 , C25B11/0489 , C25C7/02
摘要： An electrode with an outer coating for effecting an electrolytic process is provided with a protective intermediate coating consisting of a conducting insoluble polymer network formed in situ on a titanium base and containing a small amount of finely dispersed platinum group metal catalyst.A method of manufacturing the electrode comprises applying to the titanium base several layers of a solution containing a polymer precursor and a platinum metal compound which are thermally converted to the protective polymer coating, on which the outer coating is formed, more particularly by electrodepositing manganese dioxide or lead dioxide.The polymeric intermediate coating serves to protect the titanium base from oxidation, and to more particularly provide stable electrode performance with economical use of precious metal.
摘要翻译：具有用于进行电解处理的外涂层的电极具有由在钛基上原位形成并含有少量微细分散的铂族金属催化剂的导电不溶性聚合物网络组成的保护性中间涂层。制造电极的方法包括向钛基底施加几层含有聚合物前体和铂金属化合物的溶液，其被热转化成形成外涂层的保护性聚合物涂层，更特别地通过电沉积二氧化锰或二氧化铅。聚合物中间涂层用于保护钛基免受氧化，并且更具体地提供经济使用贵金属的稳定的电极性能。

57. 发明授权

US08518677B2 Microbial bioreaction process 有权
标题翻译：微生物生物反应过程
公开(公告)号：US08518677B2
公开(公告)日：2013-08-27
申请号：US12670709
申请日：2008-07-25
申请人： Hans Peter Schmidt , Michael Katz , Bo Stenhuus , Jochen Förster
发明人： Hans Peter Schmidt , Michael Katz , Bo Stenhuus , Jochen Förster
IPC分类号： C12P7/22 , C12N1/21
CPC分类号： C12N1/36 , C12N1/26 , C12P7/22
摘要： A cis- or trans-stilbenoid of the general formula (1): in which each of R1, R2, R3, R4 and R5 is hydrogen or hydroxy, or a glycosylated or oligomeric form thereof, is produced by cultivating a micro-organism producing said stilbenoid, in a multi-phase system comprising at least an aqueous first phase containing said micro-organism and a second phase immiscible with said aqueous phase in which (e.g. as which) said stilbenoid accumulates. The second phase may be said stilbenoid or a free or encapsulated solvent compatible with the growth of the micro-organism, for instance an ester.
摘要翻译：通式（1）的顺式或反式芪类化合物：其中R 1，R 2，R 3，R 4和R 5各自为氢或羟基，或其糖基化或寡聚形式，是通过培养产生微生物所述螺旋体在多相系统中包含至少含有所述微生物的含水第一相和与所述水相不混溶的第二相，其中（例如，其中）所述茋被积聚。第二相可以是所述萜类化合物或与微生物例如酯的生长相容的游离或包囊的溶剂。

58. 发明授权

US08343739B2 Metabolically engineered cells for the production of pinosylvin 有权
标题翻译：用于生产pinosylvin的代谢工程细胞
公开(公告)号：US08343739B2
公开(公告)日：2013-01-01
申请号：US12374659
申请日：2007-07-19
申请人： Michael Katz , Jochen Förster , Helga David , Hans Peter Schmidt , Malin Sendelius , Sara Peterson Bjørn , Thomas Thomasen Durhuus
发明人： Michael Katz , Jochen Förster , Helga David , Hans Peter Schmidt , Malin Sendelius , Sara Peterson Bjørn , Thomas Thomasen Durhuus
IPC分类号： C12P7/22
CPC分类号： C12P7/22 , C12N9/1029 , C12N9/88 , C12N9/93
摘要： A genetically engineered micro-organism having an operative metabolic pathway producing cinnamoyl-CoA and producing pinosylvin therefrom by the action of a stilbene synthase is used for pinosylvin production. Said cinnamic acid may be formed from L-phenylalanine by a L-phenylalanine ammonia lyase (PAL) which is one accepting phenylalanine as a substrate and producing cinammic acid therefrom, preferably such that if the PAL also accepts tyrosine as a substrate and forms coumaric acid therefrom, the ratio Km(phenylalanine)/Km(tyrosine) for said PAL is less than 1:1 and if said micro-organism produces a cinammate-4-hydroxylase enzyme (C4H), the ratio Kcat(PAL)/Kcat(C4H) is at least 2:1.
摘要翻译：具有产生肉桂酰辅酶A的功能性代谢途径并通过二苯乙烯合酶的作用从其生产pinosylvin的遗传工程微生物被用于pinosylvin生产。所说的肉桂酸可以由L-苯丙氨酸氨裂解酶（PAL）形成，L-苯丙氨酸氨裂解酶（PAL）是一种接受苯丙氨酸作为底物并由其生产肉桂酸，优选使得如果PAL也接受酪氨酸作为底物并形成香豆酸所述PAL的比例Km（苯丙氨酸）/ Km（酪氨酸）小于1:1，如果所述微生物产生肉桂酸-4-羟化酶（C4H），则比例Kcat（PAL）/ Kcat（C4H ）至少为2：1。

59. 发明授权

US08203594B2 Fallback mobile communication 有权
标题翻译：后备移动通信
公开(公告)号：US08203594B2
公开(公告)日：2012-06-19
申请号：US11853345
申请日：2007-09-11
申请人： Gary Jaspersohn , Rupa Rao , Michael Katz , Anupama Hegde , Jawad Ayaz
发明人： Gary Jaspersohn , Rupa Rao , Michael Katz , Anupama Hegde , Jawad Ayaz
IPC分类号： H04N7/14
CPC分类号： H04N7/147 , H04L65/1069 , H04L65/80 , H04L69/40 , H04M7/0072 , H04M2201/50
摘要： Conventional video call attempts encountering a device inoperable according to a desired capability will fail if the receiving device is unable to complete the call at the desired service level (i.e. video). In addition to frustrating the communication attempts between users, another issue is that resources consumed in the attempted but failed exchange are not recoverable, since the call never completed. Accordingly, configurations herein substantially overcome such shortcomings by providing a fallback mechanism that identifies a service level operable by both the initiating device and the receiving device, and completes the call at a lower service level operable by both devices. The disclosed approach allows a call to complete at an alternate service level (i.e. voice instead of video) rather than failing the call completely, resulting in a source of lost revenue to the service provider (operator).
摘要翻译：如果接收设备不能以期望的服务级别（即，视频）完成呼叫，则遇到根据所需能力不能操作的设备的常规视频呼叫尝试将失败。除了挫败用户之间的通信尝试之外，另一个问题是在尝试但失败的交换中消耗的资源不可恢复，因为该呼叫从未完成。因此，这里的配置基本上克服了这种缺点，通过提供一种后备机制，该机制识别起动设备和接收设备可操作的服务等级，并且在由两个设备可操作的较低服务级别处完成该呼叫。所公开的方法允许呼叫在备用服务级别（即，语音而不是视频）完成，而不是完全失败呼叫，从而导致服务提供商（运营商）的收入损失。

60. 发明申请

US20120030914A1 Aesthetic beaded necklace clasp 失效
标题翻译：美观串珠项链扣
公开(公告)号：US20120030914A1
公开(公告)日：2012-02-09
申请号：US12806269
申请日：2010-08-09
申请人： Michael Katz , Timothy John Lambert
发明人： Michael Katz , Timothy John Lambert
IPC分类号： A44C5/18
CPC分类号： A44C5/2076
摘要： The necklace clasp fastener for a string of beads consists of a male bead member, and a female bead member, that do not have any visible loop or eyelets for assembling and holding a string of beads together when the male and female bead members are snapped together. The resulting bead configured clasp is almost undetectable from the outside of the beaded necklace which creates an unbroken, unified string of beads for a much more aesthetic and beautiful piece of jewelry. The improved clasp of the invention provides a safety feature to guard against breakage. The two parts are designed to snap together with enough force to hold the necklace on the wearer under normal wear and use. If, however, the necklace catches on to something, the clasp will release easily from the wearer instead of breaking the necklace, and releasing the beads all over the place.
摘要翻译：用于一串珠子的项链扣环紧固件包括一个凸形胎圈部件和一个母形胎圈部件，当雄性和雌性胎缘部件咬合在一起时，它们没有任何可见的环形或孔眼，用于组装和保持一串珠子在一起。从珠状项链的外部几乎无法检测到所形成的珠形配饰，从而创造出一种不间断的，统一的珠子串，用于更美观和美丽的首饰。本发明的改进的扣具提供了防止破损的安全特征。这两个部分被设计成在足够的力下紧贴在一起，以在正常的磨损和使用下将项链保持在佩戴者身上。然而，如果这条项链抓住了一些东西，那么这个扣子就会轻松脱离穿戴者，而不是打破项链，并将珠子放在整个地方。

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