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51. 发明授权

US5589048A Method for the production of a radiographic screen 失效
标题翻译：用于生产放射线照相屏幕的方法
公开(公告)号：US5589048A
公开(公告)日：1996-12-31
申请号：US197825
申请日：1994-02-17
申请人： Nikolaas De Jaeger , Guy Damen , Gerhard Winter , Jan Van Havenbergh
发明人： Nikolaas De Jaeger , Guy Damen , Gerhard Winter , Jan Van Havenbergh
IPC分类号： C09K11/02 , C25D13/00 , G21K4/00 , H01J9/22 , C25D13/02 , C25D13/10
CPC分类号： G21K4/00 , C09K11/025 , C25D13/00 , H01J9/225 , G21K2004/06
摘要： A method for the production of a radiographic screen comprising the following steps:1) dispersing phosphor particles in an organic liquid in the presence of a charge controlling agent that charges said phosphor particles with a positive or negative net charge,2) arranging said dispersion between a pair of electrodes, wherein one of said electrodes is or carries a conductive support of said radiographic screen,3) applying and maintaining between said electrodes a sufficiently high direct current voltage to deposit charged phosphor particles onto said conductive support, and4) separating said support carrying electrophoretically deposited phosphor particles from said organic liquid,wherein the dispersing of said phosphor particles proceeds by means of an organic surface active compound acting as dispersing agent for said phosphor particles, and said phosphor particles are electrostatically charged through adsorption thereon of ionic components of said organic surface active compound and/or through adsorption of cations or anions stemming from an ionic inorganic compound incorporated in said liquid.
摘要翻译：一种用于生产射线照相屏幕的方法，包括以下步骤：1）在电荷控制剂的存在下，将荧光体颗粒分散在有机液体中，所述电荷控制剂用正或负净电荷对所述荧光体颗粒进行充电，2）将所述分散体布置在一对电极，其中所述电极之一是或承载所述放射线照相屏幕的导电支撑件，3）在所述电极之间施加和保持足够高的直流电压以将带电荧光粉颗粒沉积到所述导电支撑件上，以及4）将所述从所述有机液体中携带电泳沉积的荧光体颗粒的载体，其中所述荧光体颗粒的分散通过作为所述荧光体颗粒的分散剂的有机表面活性化合物进行，并且所述荧光体颗粒通过其上的离子组分吸附而静电所述有机表面活性化合物和/或通过吸附由所述液体中引入的离子型无机化合物产生的阳离子或阴离子。

52. 发明授权

US4907125A Circuit module including a plate-shaped circuit carrier of glass or ceramic 失效
标题翻译：电路模块包括玻璃或陶瓷的板状电路载体
公开(公告)号：US4907125A
公开(公告)日：1990-03-06
申请号：US200244
申请日：1988-05-31
申请人： Karl-Gerd Drekmeier , Gerhard Winter
发明人： Karl-Gerd Drekmeier , Gerhard Winter
IPC分类号： H01L23/14 , H05K1/02 , H05K1/05
CPC分类号： H05K1/0203 , H01L23/142 , H05K1/053 , H01L2924/0002 , H01L2924/09701 , H05K2201/09745 , H05K2201/10181 , H05K2201/10386 , H05K2201/10553
摘要： A metal plate is connected over a large area to one side of a glass or ceramic substrate for good heat distribution and removal. The metal plate consists of three layers, namely two outer copper layers and a center Invar layer having the thickness ratio of the layers of approximately 20:60:20. As a result of such a selected thickness ratio, the metal plate exhibits approximately the same coefficient of thermal expansion as the substrate and an inadmissible bending of the substrate or overstressing of the solder or adhesive line between the substrate and metal plate is prevented.
摘要翻译：金属板大面积连接到玻璃或陶瓷基板的一侧，用于良好的散热和去除。金属板由三层构成，即两层外层铜层和厚度比约为20:60:20的中心殷钢层。作为这样选择的厚度比的结果，金属板表现出与基板大致相同的热膨胀系数，并且基板的不允许的弯曲或者阻止基板和金属板之间的焊料或粘合剂线的过应力。

53. 再颁专利

USRE31827E Metalized recording carrier for recording instruments, and method of its manufacture 失效
标题翻译：用于记录仪器的金属化记录载体及其制造方法
公开(公告)号：USRE31827E
公开(公告)日：1985-02-05
申请号：US555295
申请日：1983-11-25
申请人： Richard Hohn , Werner Jung , Gerhard Winter , Siegfried Woerner
发明人： Richard Hohn , Werner Jung , Gerhard Winter , Siegfried Woerner
IPC分类号： B41J2/425 , B41M5/24
CPC分类号： B41M5/245
摘要： To prevent the formation of scratches, surface discontinuities, slide tracks or striations, for example due to sliding of electrodes (20) over the metal layer (12) of a metalized recording medium, a protective surface coating (13) of low-friction sliding protective material is applied in the form of discontinuous islands over the metal layer (12). The discontinuities permit electrical contact between the electrode (20) and the metal layer (12) although the protective surface coating (13) has insulating properties. The coating (13) may be polymerized hexamethyl-disiloxane, hexafluoropropylene, or Teflon, polymerized, preferably in hot cathode glow discharge; or a metallic soap. The protective layer is hydrophobic in the form of islands of a thickness of between 10.sup.-9 m to 10.sup.-7 m, preferably about 1 to 2.times.10.sup.-8 m, thus protecting the underlying metal layer (12) against damage by the electrode (20), and attack by moisture or dampness from the ambient atmosphere. A surface portion can be rendered hydrophilic to permit writing on the recording paper by a felt pen, with aqueous ink or the like.

54. 发明授权

US4173485A Production of zinc and alkaline earth metal titanates 失效
标题翻译：生产锌和碱土金属钛酸盐
公开(公告)号：US4173485A
公开(公告)日：1979-11-06
申请号：US873995
申请日：1978-01-31
申请人： Peter Woditsch , Gerhard Winter , Gunter Linde , Friedhelm Muller
发明人： Peter Woditsch , Gerhard Winter , Gunter Linde , Friedhelm Muller
IPC分类号： C01G23/00 , C09C1/36 , C04B35/46 , C04B31/02 , C09C1/04
CPC分类号： C01G23/003 , C01G23/002 , C09C1/36 , C01P2002/32 , C01P2002/34 , C01P2002/52 , C01P2004/52 , C01P2004/62 , C01P2006/60
摘要： Titanates of zinc and/or alkaline earth metals are produced by simultaneously adding to a suspension of finely divided TiO.sub.2, maintained at a substantially constant pH above about 8, a solution of a salt of zinc and/or alkaline earth metal and alkali to form a hydroxide precipitate. Filtration produces a filter cake mixture of TiO.sub.2 and hydroxide and calcination at above 500.degree. C. produces the desired titanate of narrow particle size distribution and desirable optical properties. Non-simultaneous addition results in a non-filterable material. Zinc, magnesium and/or calcium are preferred and doping elements such as aluminum, phosphorus, boron and/or silicon may also be present.
摘要翻译：锌和/或碱土金属的钛酸盐通过同时加入到细分散的TiO 2的悬浮液中，将其保持在高于约8的基本上恒定的pH，锌和/或碱土金属和碱的盐溶液形成氢氧化物沉淀。过滤产生TiO 2和氢氧化物的滤饼混合物并在500℃以上煅烧，产生窄粒度分布的所需钛酸盐和所需的光学性质。非同时加入导致不可过滤的材料。优选锌，镁和/或钙，也可以存在诸如铝，磷，硼和/或硅的掺杂元素。

55. 发明授权

US4010233A Production of inorganic fibers 失效
标题翻译：生产无机纤维
公开(公告)号：US4010233A
公开(公告)日：1977-03-01
申请号：US424229
申请日：1973-12-12
申请人： Gerhard Winter , Manfred Mansmann , Hans Zirngibl
发明人： Gerhard Winter , Manfred Mansmann , Hans Zirngibl
IPC分类号： C04B35/622 , C08J5/04 , D01F9/08 , D01D5/04 , C04B35/10
CPC分类号： C08J5/044 , C04B35/62231 , D01F9/08 , C08J2363/00 , Y10S264/19
摘要： The invention relates to the production of inorganic fibers comprising a metal oxide phase and a finely divided disperse phase distributed throughout the oxide phase, the disperse phase constituting about 0.5 to 50% by weight of the fiber. The process involves preferably dry spinning a solution in water or an organic solvent of fiber forming components which, when heated to temperature of from 500.degree. to 1600.degree. C either in an inert or in a reactive atmosphere, form at least two phases with a miscibility gap, of which one phase is an oxide phase containing the other phase in very finely disperse form. Preferably, the solution contains a metal salt, the anion of which contains carbon so that upon heating there is formed an oxide phase comprising the oxide of said metal having carbon dispersed therein; if carbon is not in the anion, its precursor may be an organic compound, such as a polymer, present in the solution. Other materials which may constitute the disperse phase include boron as well as carbides, nitrides, borides or silicides and some metals. The resulting fiber are of low porosity and high modulus and impart superior properties to plastics, metals, glasses and ceramics reinforced therewith.
摘要翻译：本发明涉及包含分布在整个氧化物相中的金属氧化物相和细分散分散相的无机纤维的生产，分散相占纤维的约0.5-50重量％。该方法优选将水溶液或纤维形成组分的有机溶剂干燥纺丝，当在惰性或反应性气氛中加热至500℃至1600℃的温度时，形成至少两相具有混溶性间隙，其中一相是以非常细的分散形式含有另一相的氧化物相。优选地，溶液含有金属盐，其阴离子含有碳，使得在加热时形成包含其中分散有碳的所述金属的氧化物的氧化物相; 如果碳不在阴离子中，其前体可以是存在于溶液中的有机化合物，如聚合物。可能构成分散相的其他材料包括硼以及碳化物，氮化物，硼化物或硅化物以及一些金属。所得到的纤维具有低孔隙率和高模量，并赋予其对其进行增强的塑料，金属，玻璃和陶瓷优异的性能。

56. 发明授权

US3963585A Distillation of titanium tetrachloride in solution with selected amines 失效
标题翻译：在选择的胺溶液中蒸馏四氯化钛
公开(公告)号：US3963585A
公开(公告)日：1976-06-15
申请号：US465954
申请日：1974-05-01
申请人： Gerhard Winter , Walter Deissmann , Walter Gutsche , Peter Woditsch
发明人： Gerhard Winter , Walter Deissmann , Walter Gutsche , Peter Woditsch
IPC分类号： C01G23/02 , B01D3/34
CPC分类号： C01G23/024
摘要： In the purification of impure titanium tetrachloride comprising adding an agent to said titanium tetrachloride and thereafter distilling off purified titanium tetrachloride while leaving the impurity in the distillation residue, the improvement which comprises employing as said agent at least one amine of the formula ##EQU1## in which R.sub.1 and R.sub.2 each independently is hydrogen, alkyl or alkenyl of up to 6 carbon atoms, cycloalkyl of 5 to 7 carbon atoms, or aryl, andR.sub.3 is cycloalkyl of 5 to 7 ring carbon atoms, or aryl, orR.sub.2 together with R.sub.3 is butylene, pentylene or hexylene, in which eventR.sub.1 is hydrogen, alkyl of up to 6 carbon atoms or aryl.The preferred agents are aniline, cyclohexylamine, N,N-dimethyl-aniline, diphenylamine, 2,3-dimethyl-aniline and 2,6-dimethyl-aniline. The process serves to remove vanadium impurities.
摘要翻译：在不纯的四氯化钛的纯化中，包括在所述四氯化钛中加入试剂，然后蒸馏出纯化的四氯化钛，同时留下蒸馏残余物中的杂质，其改进包括使用至少一种式R 2 R 1 -N 其中R 1和R 2各自独立地为氢，至多6个碳原子的烷基或烯基，5至7个碳原子的环烷基或芳基，R 3为5至7个环碳原子的环烷基，或芳基或R 2 与R 3一起是亚丁基，亚戊基或亚己基，其中R1是氢，高达6个碳原子的烷基或芳基。

57. 发明授权

US08663606B2 Method of producing a cationic liposomal preparation comprising a lipophilic compound 有权
标题翻译：制备包含亲脂性化合物的阳离子脂质体制剂的方法
公开(公告)号：US08663606B2
公开(公告)日：2014-03-04
申请号：US13278801
申请日：2011-10-21
申请人： Carsten Mundus , Christian Welz , Oliver Schramel , Heinrich Haas , Thomas Fichert , Brita Schulze , Toralf Peymann , Uwe Michaelis , Michael Teifel , Friedrich Gruber , Gerhard Winter
发明人： Carsten Mundus , Christian Welz , Oliver Schramel , Heinrich Haas , Thomas Fichert , Brita Schulze , Toralf Peymann , Uwe Michaelis , Michael Teifel , Friedrich Gruber , Gerhard Winter
IPC分类号： A61K9/127 , A61K31/685 , A61K31/56 , A61K31/4375 , A61K31/427 , A61K31/337
CPC分类号： A61K31/337 , A61K9/127 , A61K9/1272 , A61K31/335 , A61K31/47 , A61K31/4745 , A61K47/34 , A61K47/543 , A61K47/56 , A61K47/6911 , A61K49/1812 , B82Y5/00 , C07D471/14
摘要： A method for producing a cationic liposomal preparation comprising a lipophilic active compound with physical and chemical stability during manufacturing, storing and reconstituting, and further a cationic liposomal preparation obtainable by this method as well as specific cationic liposomal preparations as well as pharmaceutical compositions are disclosed.
摘要翻译：公开了一种阳离子脂质体制剂的制造方法，其包括在制造，储存和重构过程中具有物理和化学稳定性的亲脂性活性化合物，以及可通过该方法获得的阳离子脂质体制剂以及特定的阳离子脂质体制剂以及药物组合物。

58. 发明授权

US08075913B2 Method of producing a cationic liposomal preparation comprising a lipophilic compound 有权
标题翻译：制备包含亲脂性化合物的阳离子脂质体制剂的方法
公开(公告)号：US08075913B2
公开(公告)日：2011-12-13
申请号：US12859000
申请日：2010-08-18
申请人： Carsten Mundus , Christian Welz , Oliver Schramel , Heinrich Haas , Thomas Fichert , Brita Schulze , Toralf Peymann , Uwe Michaelis , Michael Teifel , Friedrich Gruber , Gerhard Winter
发明人： Carsten Mundus , Christian Welz , Oliver Schramel , Heinrich Haas , Thomas Fichert , Brita Schulze , Toralf Peymann , Uwe Michaelis , Michael Teifel , Friedrich Gruber , Gerhard Winter
IPC分类号： A61K9/127 , A61K31/37 , A61P35/00
CPC分类号： A61K31/337 , A61K9/127 , A61K9/1272 , A61K31/335 , A61K31/47 , A61K31/4745 , A61K47/34 , A61K47/543 , A61K47/56 , A61K47/6911 , A61K49/1812 , B82Y5/00 , C07D471/14
摘要： A method for producing a cationic liposomal preparation comprising a lipophilic active compound with physical and chemical stability during manufacturing, storing and reconstituting, and further a cationic liposomal preparation obtainable by this method as well as specific cationic liposomal preparations as well as pharmaceutical compositions are disclosed.
摘要翻译：公开了一种阳离子脂质体制剂的制造方法，其包括在制造，储存和重构过程中具有物理和化学稳定性的亲脂性活性化合物，以及可通过该方法获得的阳离子脂质体制剂以及特定的阳离子脂质体制剂以及药物组合物。

59. 发明授权

US08034906B2 Crystalline anti-hTNFalpha antibodies 有权
标题翻译：结晶抗hTNFalpha抗体
公开(公告)号：US08034906B2
公开(公告)日：2011-10-11
申请号：US11977677
申请日：2007-10-25
申请人： David W. Borhani , Wolfgang Fraunhofer , Hans-Juergen Krause , Anette Koenigsdorfer , Gerhard Winter , Stefan Gottschalk
发明人： David W. Borhani , Wolfgang Fraunhofer , Hans-Juergen Krause , Anette Koenigsdorfer , Gerhard Winter , Stefan Gottschalk
IPC分类号： C07K16/00 , G01N31/00
CPC分类号： C07K16/241 , A61K9/50 , A61K39/3955 , C07K2299/00 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要： The present invention relates to a batch crystallization method for crystallizing an anti-hTNFalpha antibody which allows the production of said antibody on an industrial scale; antibody crystals as obtained according to said method; compositions containing said crystals as well as methods of use of said crystals and compositions.
摘要翻译：本发明涉及一种用于使抗hTNFα抗体结晶的分批结晶方法，其允许以工业规模生产所述抗体; 根据所述方法获得的抗体晶体; 含有所述晶体的组合物以及所述晶体和组合物的使用方法。

60. 发明申请

US20100297214A1 PERCOLATIVE DRYING FOR THE PREPARATION OF PARTICLES 审中-公开
标题翻译：用于制备颗粒的干性干燥剂
公开(公告)号：US20100297214A1
公开(公告)日：2010-11-25
申请号：US12445719
申请日：2007-10-26
申请人： Heinrich Haas , Klaus Drexler , Michael Wiggenhorn , Gerhard Winter
发明人： Heinrich Haas , Klaus Drexler , Michael Wiggenhorn , Gerhard Winter
IPC分类号： A61K9/127 , F26B5/06
CPC分类号： A61K9/1682 , A61K9/1272
摘要： The present invention relates to dry particles and methods of preparing the same, in particular to methods of producing dry particles comprising a thermally labile component such as a colloidal system or a thermally labile biopharmaceutical compound, to the use of such dry particles, and to pharmaceutical compositions comprising the same.
摘要翻译：本发明涉及干颗粒及其制备方法，特别涉及制备干燥颗粒的方法，所述干燥颗粒包括热不稳定组分如胶体系或热不稳定的生物药物化合物，以及使用这种干燥颗粒的药物包含其的组合物。

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