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51. 发明申请

US20090220863A1 LITHIUM ION SECONDARY BATTERY 有权
标题翻译：锂离子二次电池
公开(公告)号：US20090220863A1
公开(公告)日：2009-09-03
申请号：US12354039
申请日：2009-01-15
申请人： Naoki KIMURA
发明人： Naoki KIMURA
IPC分类号： H01M4/24
CPC分类号： H01M10/0525 , H01M4/366 , H01M4/587 , Y02E60/122 , Y02T10/7011
摘要： A lithium ion secondary battery is capable of improving the energy density and power density and excellent in high rate cycle characteristics applicable to hybrid cars, etc. The lithium ion secondary battery including a positive electrode of a lithium transition metal complex oxide, a negative electrode for absorbing/releasing lithium, and a non-aqueous electrolyte containing a lithium salt, in which the negative electrode has a negative electrode active material using a non-graphitizing carbon (spacing d(002) of 0.360 nm or more by XRD) and a graphitizing carbon (spacing d(002) of 0.339 nm or more and less than 0.360 nm by XRD) surface-modified at a thickness in a range from 10 nm to 100 nm in admixture, comprising the non-graphitizing carbon and the graphitizing carbon at a ratio in the range of 90 to 50 wt %:10 to 50 wt % and, further, graphitizing carbon having a grain size larger than that of the non-graphitizing carbon is used.
摘要翻译：锂离子二次电池能够提高能量密度和功率密度以及适用于混合动力汽车等的高速循环特性优异。锂离子二次电池包括锂过渡金属复合氧化物的正极，负极吸收/释放锂，以及含有锂盐的非水电解质，其中负极具有使用非石墨化碳的负极活性物质（通过XRD的间隔d（002）为0.360nm以上）和石墨化碳（通过XRD测定的0.339nm以上，0.339nm以上且小于0.360nm的间隔d（002））在10nm〜100nm的范围内进行表面改性，包含非石墨化碳和石墨化碳比率在90〜50重量％的范围内：10〜50重量％，进一步使用比非石墨化碳的粒径大的石墨化碳。

52. 发明申请

US20090161366A1 PORCELAIN ENAMEL SUBSTRATE FOR MOUNTING LIGHT EMITTING DEVICE AND METHOD OF MANUFACTURING THE SAME, LIGHT EMITTING DEVICE MODULE, ILLUMINATION DEVICE, DISPLAY UNIT AND TRAFFIC SIGNAL 有权
标题翻译：用于安装发光装置的PORCELAIN ENAMEL基板及其制造方法，发光装置模块，照明装置，显示单元和交通信号
公开(公告)号：US20090161366A1
公开(公告)日：2009-06-25
申请号：US12372529
申请日：2009-02-17
申请人： Naoki KIMURA , Masakazu Ohashi , Shunichirou Hirafune
发明人： Naoki KIMURA , Masakazu Ohashi , Shunichirou Hirafune
IPC分类号： F21V7/00 , B05D5/12
CPC分类号： H01L33/641 , G02F1/133603 , G02F1/133608 , H01L33/60 , H01L2224/45144 , H01L2224/48091 , H01L2924/181 , H05K1/053 , H05K1/183 , Y10S362/80 , H01L2924/00014 , H01L2924/00 , H01L2924/00012
摘要： A porcelain enamel substrate (1) mounts a light emitting element in which a porcelain enamel layer (5) is coated onto a surface of a core metal (4), and a reflective cup portion (7) that has a flat bottom surface and a sloping portion that surrounds this bottom surface is provided on a light emitting element mounting surface, and an electrode (6) for energizing a light emitting element (3) is provided on the light emitting element mounting surface, and the thickness of the electrode (6) within the reflective cup portion (7) is within a range of 5 μm to 100 μm.
摘要翻译：瓷釉基体（1）将其中涂覆有瓷釉层（5）的发光元件安装在芯金属（4）的表面上，并且具有平坦的底表面和反射杯部分（7）的反射杯部分围绕该底面的倾斜部设置在发光元件安装面上，在发光元件安装面上设置用于赋能发光元件（3）的电极（6），电极（6）的厚度）在5μm到100μm的范围内。

53. 发明申请

US20070280951A1 Cell Death Inducing Agents 审中-公开
标题翻译：细胞死亡诱导剂
公开(公告)号：US20070280951A1
公开(公告)日：2007-12-06
申请号：US10582304
申请日：2004-12-10
申请人： Naoki Kimura , Masayuki Tsuchiya , Masahiko Nanami , Takashi Tomimatsu , Shigeto Kawai
发明人： Naoki Kimura , Masayuki Tsuchiya , Masahiko Nanami , Takashi Tomimatsu , Shigeto Kawai
IPC分类号： A61K39/395 , A61P35/00 , A61P37/00 , C07H21/00 , C07K16/00 , C12N1/00 , C12N15/63 , C12N5/00 , C12P21/00
CPC分类号： C07K16/00 , C07K2317/622 , C07K2317/73
摘要： The present inventors constructed a DNA expression vector encoding 2D7sc(Fv)2 in which the heavy chain variable region sequence (VH) and the light chain variable region sequence (VL) of the 2D7 antibody is arranged in the order of VH-VL-VH-VL, and these sequences are linked by a 15-mer linker. The vector was introduced into CHO cells and a 2D7sc(Fv)2-producing expression cell line was established. When 2D7sc(Fv)2 was expressed in this cell line, purified, and cell death-inducing experiments performed, 2D7sc(Fv)2 was found to have a concentration-dependent cell death-inducing activity.
摘要翻译：本发明人构建了编码2D7sc（Fv）2的DNA表达载体，其中2D7抗体的重链可变区序列（VH）和轻链可变区序列（VL）以VH-VL-VH -VL，并且这些序列通过15聚体连接子连接。将载体导入CHO细胞，并建立产生2D7sc（Fv）2的表达细胞系。当在该细胞系中表达2D7sc（Fv）2时，发现2D7sc（Fv）2的纯化和细胞死亡诱导实验具有浓度依赖性细胞死亡诱导活性。

54. 发明申请

US20070003556A1 Modified antibodies against cd22 and utilization thereof 审中-公开
标题翻译：针对cd22的修饰抗体及其应用
公开(公告)号：US20070003556A1
公开(公告)日：2007-01-04
申请号：US10550934
申请日：2004-03-31
申请人： Masayuki Tsuchiya , Naoki Kimura , Tatsuya Fukuda
发明人： Masayuki Tsuchiya , Naoki Kimura , Tatsuya Fukuda
IPC分类号： A61K39/395 , C07K16/30
CPC分类号： C07K16/2803 , C07K2317/622 , C07K2317/73
摘要： CD22 diabodies, in which heavy-chain and light-chain variable regions are linked by a 5-mer linker, were produced based on known sequence information for two types of anti-CD22 antibodies. The two diabodies produced were analyzed for their activity of binding to lymphoma cells and inducing lymphoma cell death (apoptosis). As a result, both diabodies were revealed to bind to the B-lymphoma cell line, “Raji”, and to have apoptosis-inducing activity towards Raji cells as well as towards another B-lymphoma cell line: Daudi cells. These results show that minibodies of antibodies that recognize CD22 can be used as apoptosis-inducing agents for tumor cells such as lymphoma cells.
摘要翻译：基于两种类型的抗-CD22抗体的已知序列信息产生CD22双抗体，其中重链和轻链可变区通过5-聚体连接子连接。分析所产生的两种双抗体与淋巴瘤细胞结合的活性，诱导淋巴瘤细胞死亡（凋亡）。结果，双抗体被揭示结合到B淋巴瘤细胞系“Raji”，并且对Raji细胞以及另一B淋巴瘤细胞系具有凋亡诱导活性：Daudi细胞。这些结果表明识别CD22的抗体的小体抗体可以用作肿瘤细胞如淋巴瘤细胞的凋亡诱导剂。

55. 发明申请

US20060188577A1 Element having bioactive substance fixed thereto 审中-公开
标题翻译：具有固定有生物活性物质的元件
公开(公告)号：US20060188577A1
公开(公告)日：2006-08-24
申请号：US10553092
申请日：2004-04-16
申请人： Naoki Kimura , Ryuichi Oda , Gen Masuda , Toshifumi Hashiba , Kazutoshi Hayakawa
发明人： Naoki Kimura , Ryuichi Oda , Gen Masuda , Toshifumi Hashiba , Kazutoshi Hayakawa
IPC分类号： A61K9/14
CPC分类号： G01N33/544 , C12Q1/6834 , G01N33/54313
摘要： By using a biologically active substance-immobilized device, which comprises a base particle comprising a core particle and an organic compound having two or more hydrophilic groups and immobilized on the core particle by a chemical bond and a biologically active substance bonded to the base particle via the organic compound, a substance specifically bonding to the biologically active substance is detected or measured.
摘要翻译：通过使用生物活性物质固定化装置，其包括含有核心颗粒和具有两个或更多个亲水基团的有机化合物的基础颗粒，并通过化学键固定在芯颗粒上，并且通过粘合到基础颗粒的生物活性物质经由检测或测量有机化合物，特异性结合生物活性物质的物质。

56. 发明申请

US20060051750A1 Method for fixing biomolecule on carrier 审中-公开
标题翻译：生物分子固定在载体上的方法
公开(公告)号：US20060051750A1
公开(公告)日：2006-03-09
申请号：US10501691
申请日：2003-01-31
申请人： Ryuichi Oda , Naoki Kimura
发明人： Ryuichi Oda , Naoki Kimura
IPC分类号： C12Q1/68 , G01N33/53 , B05D3/00
CPC分类号： C07H21/00 , C07B2200/11 , C40B40/00
摘要： A nucleic acid is immobilized on a carrier by spotting a solution of the nucleic acid on the carrier comprising a synthetic resin such as polycarbonate, polymethyl methacrylate, acrylonitrile/butadiene/styrene copolymer, polyethylene, polyethylene terephthalate, polyphenol, polystyrene, polyacrylonitrile, polyvinyl chloride, or aramide, drying the solution, and irradiating the carrier with an ultraviolet ray containing a component having a wavelength of 280 nm, preferably for 100 mJ/cm2 or more.
摘要翻译：将核酸固定在载体上，包含合成树脂如聚碳酸酯，聚甲基丙烯酸甲酯，丙烯腈/丁二烯/苯乙烯共聚物，聚乙烯，聚对苯二甲酸乙二醇酯，多酚，聚苯乙烯，聚丙烯腈，聚氯乙烯或芳族聚酰胺，干燥溶液，并用含有波长280nm的成分的紫外线照射载体，优选为100mJ / cm 2以上。

57. 发明授权

US06882902B2 Method of and apparatus for thermal analysis, method of and apparatus for calculating thermal conditions, computer product 失效
标题翻译：计算机产品的热分析方法和装置，计算机热处理方法和装置
公开(公告)号：US06882902B2
公开(公告)日：2005-04-19
申请号：US09916584
申请日：2001-07-30
申请人： Yuriko Nobuhara , Naoki Kimura , Yoshio Nakamura , Satoru Isogai
发明人： Yuriko Nobuhara , Naoki Kimura , Yoshio Nakamura , Satoru Isogai
IPC分类号： B23K3/04 , B23K1/00 , B23K1/008 , B23K31/02 , B23K101/42 , G01K7/42 , H05K3/34 , G05D23/00
CPC分类号： G01K7/42 , H05K3/3494
摘要： The physical property data of the object to be heated, set temperatures of heaters and blowers are provided to a reflow apparatus, and view factor setting data for determining the view factor of the surface-mounted circuit board are input. From the input these data, the number of heaters and blowers, and the heating characteristic data peculiar to the reflow apparatus, such as the heat transfer coefficient, the speed of conveyor and the like, the view factor is simply determined, and the temperature of the surface-mounted circuit board at the time of passing through the reflow apparatus is calculated with respect to the board and parts mounted thereon, using the determined view factor.
摘要翻译：输入被加热物的物理属性数据，将加热器和鼓风机的温度设定为回流装置，并且输入用于确定表面安装电路基板的视图系数的观察因子设定数据。从输入这些数据，加热器和鼓风机的数量以及回流装置特有的加热特性数据，例如传热系数，输送机速度等，简单地确定视图因子，并且温度使用确定的观察因子，计算通过回流装置时的表面安装电路板相对于安装在其上的板和部件。

58. 发明授权

US06717127B2 Semiconductor image pickup device having function circuit block 有权
标题翻译：具有功能电路块的半导体图像拾取装置
公开(公告)号：US06717127B2
公开(公告)日：2004-04-06
申请号：US10161688
申请日：2002-06-05
申请人： Naoki Kimura , Hiroki Ui
发明人： Naoki Kimura , Hiroki Ui
IPC分类号： H01L2700
CPC分类号： H04N5/335 , H04N9/045
摘要： To check circuit characteristics of a function circuit block such as a gain circuit, data indicating an initial set point is set in a data set unit setting time period T1. A plurality of electric signals from converting optical signals of pixel cells for an image are accumulated in a pixel array in an accumulating time period T2. In a data outputting time period T3, a plurality of different set points are set in an automatic set point changing block according to the data set in the data set unit. The electric signals are repeatedly corrected in the gain circuit at a gain while changing the gain corresponding to each of the set points. The corrected electric signals corresponding to the set points are output from a semiconductor image pickup device. In a time period T4, the corrected electric signals is calculated, and the gain circuit characteristics are checked.
摘要翻译：为了检查诸如增益电路的功能电路块的电路特性，在数据设定单元设置时间段T1中设置指示初始设定点的数据。来自转换图像的像素单元的光信号的多个电信号在累积时间段T2中被累积在像素阵列中。在数据输出时间段T3中，根据数据集单元中设定的数据，将多个不同的设定点设定在自动设定点变更块中。在改变对应于每个设定点的增益的同时，增益电路中的电信号被重复地校正。从半导体图像拾取装置输出对应于设定点的校正后的电信号。在时间段T4中，计算校正后的电信号，并检查增益电路特性。

59. 发明授权

US06684012B2 Optical communication module and process for producing the same 失效
标题翻译：光通信模块及其制造方法
公开(公告)号：US06684012B2
公开(公告)日：2004-01-27
申请号：US09950766
申请日：2001-09-13
申请人： Naoki Kimura
发明人： Naoki Kimura
IPC分类号： G02B630
CPC分类号： G02B6/12007 , G02B6/29361 , G02B6/29385 , G02B6/423 , G02B6/4246
摘要： An optical communication module for optical signal transmission having a structure adopting folding at a filter and a process for producing the same is disclosed. An optical waveguide is formed as a straight waveguide for send/receive of an optical signal. A groove is formed on the optical waveguide substrate. The groove is preferably a V groove positioned diagonally to the axial center line of the substrate. The V groove is disposed in the same direction as an optical waveguide. The above construction can realize an optical send/receive module, which can eliminate the need to provide a bent waveguide, enables all waveguides to be constructed by a straight waveguide, has a small size, and can realize mass production at low cost.
摘要翻译：公开了一种用于具有在滤波器上折叠的结构的光信号传输用光通信模块及其制造方法。光波导形成为用于发送/接收光信号的直波导管。在光波导基板上形成槽。槽优选为与衬底的轴向中心线对角定位的V形槽。 V槽沿与光波导相同的方向设置。上述结构可以实现光发送/接收模块，可以消除提供弯曲波导的需要，使所有波导由直波导构成，具有体积小，可实现低成本的批量生产。

60. 发明授权

US06567447B1 Semiconductor laser device and semiconductor laser module using the same 有权
标题翻译：半导体激光器件和半导体激光器模块使用相同
公开(公告)号：US06567447B1
公开(公告)日：2003-05-20
申请号：US09680153
申请日：2000-10-03
申请人： Junji Yoshida , Naoki Tsukiji , Akira Iketani , Naoki Kimura , Jun Niekawa , Toshio Kimura , Takeshi Aikiyo
发明人： Junji Yoshida , Naoki Tsukiji , Akira Iketani , Naoki Kimura , Jun Niekawa , Toshio Kimura , Takeshi Aikiyo
IPC分类号： H01S500
CPC分类号： H01S5/34 , B82Y20/00 , H01S5/02216 , H01S5/02284 , H01S5/02415 , H01S5/02492 , H01S5/028 , H01S5/1039 , H01S5/146 , H01S5/3403
摘要： In the semiconductor laser device of the present invention, a semiconductor stacked structure including an active layer comprising a strained multi-quantum well structure is formed on a substrate 1, a cavity length is larger than 1000 &mgr;m but equal to or smaller than 1800 &mgr;m, and a low-reflection film S1 having a reflectance of 3% or less is formed on one facet and a high-reflection film S2 having a reflectance of 90% or more is formed on the other facet. The semiconductor laser module has a structure in which the semiconductor laser device is set to a cooling device constituted by electrically alternately arranging 40 pairs or more of the Peltier elements and holding them by top and bottom ceramic plates and sealed in the package. A grating having a reflection bandwidth of 1.5 nm or less is formed on an optical fiber to be built in.
摘要翻译：在本发明的半导体激光装置中，在基板1上形成包括应变多量子阱结构的有源层的半导体层叠结构，空洞长度大于1000μm，但等于或小于1800μm，并且在一个面上形成反射率为3％以下的低反射膜S1，另一方面形成反射率为90％以上的高反射膜S2。半导体激光器模块具有这样的结构，其中半导体激光器件被设置为通过电气交替地布置40对或更多个珀耳帖元件并由顶部和底部陶瓷板保持并且密封在封装中的冷却装置。在内置的光纤上形成具有1.5nm以下的反射带宽的光栅。

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