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    • 43. 发明授权
    • Atmospheric pressure ion source with exhaust system
    • 带排气系统的大气压离子源
    • US08841607B2
    • 2014-09-23
    • US13602249
    • 2012-09-03
    • Zicheng YangRoy P MoellerStephen Zanon
    • Zicheng YangRoy P MoellerStephen Zanon
    • H01J49/26
    • H01J49/044H01J49/165H01J49/168H01J49/24
    • An atmospheric pressure ion source, employing the principle of electrospray ionization, chemical ionization, or photo-ionization, comprises a spray probe for spraying a liquid into an ionization chamber and has an exhaust port through which residual spray mist and waste gas, such as evaporated solvent, are extracted. The ion source further comprises an exhaust system comprising a conduit which is connected to the exhaust port. The conduit has a transition from a first cross-section to a second cross section at a point downstream of the exhaust port wherein the second cross section is reduced in relation to the first cross section. Gas is injected via a gas injector into the conduit in a region of the transition to create a low pressure region that removes unwanted material from the chamber.
    • 使用电喷雾电离,化学电离或光电离原理的大气压离子源包括用于将液体喷射到电离室中的喷射探针,并具有排气口,残留的喷雾和废气如蒸发 溶剂,萃取。 离子源还包括排气系统,其包括连接到排气口的导管。 导管在排气口下游的点处具有从第一横截面到第二横截面的过渡,其中第二横截面相对于第一横截面减小。 气体通过气体注入器在过渡区域中被注入导管,以产生从腔室去除不需要的材料的低压区域。
    • 44. 发明授权
    • Inductively coupled plasma MS/MS mass analyzer
    • 电感耦合等离子体质谱仪MS / MS
    • US08610053B2
    • 2013-12-17
    • US13734378
    • 2013-01-04
    • Agilent Technologies, Inc.
    • Noriyuki YamadaJun KitamotoTakeo Kuwabara
    • B01D59/44
    • H01J49/0495H01J49/105H01J49/24
    • An inductively coupled plasma MS/MS mass analyzer (ICP-MS/MS) may include a first vacuum chamber which draws plasma containing an ionized sample into vacuum, a second vacuum chamber which includes a device or means which extracts and guides ions as an ion beam from the ions output from the first vacuum chamber, a third vacuum chamber which has a first ion optical separation device or means, a fourth vacuum chamber which has a cell into which reaction gas is introduced, and a fifth vacuum chamber which has a second optical separation device or means and a detector, wherein the second vacuum chamber and third vacuum chamber are individually evacuated.
    • 电感耦合等离子体质谱分析仪(ICP-MS / MS)可以包括将包含电离样品的等离子体吸入真空中的第一真空室,第二真空室包括提取和引导离子作为离子的装置或装置 从第一真空室输出的离子的光束,具有第一离子光学分离装置或装置的第三真空室,具有引入反应气体的单元的第四真空室和具有第二真空室的第二真空室 光学分离装置或装置和检测器,其中第二真空室和第三真空室被单独排空。
    • 46. 发明申请
    • MULTIMODE CELLS AND METHODS OF USING THEM
    • 多重细胞及其使用方法
    • US20130284917A1
    • 2013-10-31
    • US13854458
    • 2013-04-01
    • HAMID BADIEIKAVEH KAHEN
    • HAMID BADIEIKAVEH KAHEN
    • H01J49/24
    • H01J49/24H01J49/005
    • A mass spectrometer system is provided that is configurable for operation in both a Kinetic Energy Discrimination (KED) and Dynamic Reaction Cell (DRC). A pressurized or collision cell included in the mass spectrometer encloses a quadrupole and is coupled to a source of both inert and reactive gas. To operate in the KED mode, the collision cell can be filled with a quantity of the inert gas and an energy barrier formed between the collision cell and a downstream mass analyzer. Interferer ions collided with the inert gas can lose on average more energy relative to analyte ions of the same mass to charge ratio and can thus be trapped by the energy barrier in greater proportions. To operate instead in the DRC mode, the collision cell can be filled with a quantity of gas that is reactive with the interferer ions only. Mass filtering of the product ions can then transmit proportionally more of the analyte ions to the downstream mass analyzer. A mode controller coordinates the two modes of operation.
    • 提供了可配置为在动能分辨(KED)和动态反应池(DRC)中操作的质谱仪系统。 包含在质谱仪中的加压或碰撞电池包围四极杆,并与惰性气体和反应性气体源连接。 为了在KED模式下操作,可以在碰撞池和下游质量分析器之间填充一定数量的惰性气体和能量障碍物。 与惰性气体碰撞的干扰物相对于具有相同质荷比的分析物离子平均可损失更多的能量,因此可以以更大的比例被能量障碍物捕获。 为了在DRC模式下操作,碰撞单元可以填充一定量的仅与干扰源离子反应的气体。 然后,产物离子的质量过滤可以成比例地将更多的分析物离子传输到下游质量分析器。 模式控制器协调两种操作模式。
    • 47. 发明授权
    • Mass spectrometer
    • 质谱仪
    • US08487239B2
    • 2013-07-16
    • US12474530
    • 2009-05-29
    • Kevin R. HowesEliot PowellPaul Read
    • Kevin R. HowesEliot PowellPaul Read
    • B01D59/44
    • H01J49/10H01J49/24
    • An ion source, a mass spectrometer and a method of enhancing the performance of an ion source for use with a mass spectrometer. The ion source has a housing incorporating an ion source enclosure defining a chamber and an outer cover remote from the chamber. A fluid flow passageway is provided between the ion source enclosure and the outer cover. The method of the invention comprising supplying to the ion source housing a regulated flow of fluid through the fluid passageways so as to maintain the ion source enclosure within a predetermined temperature range of substantially between 60° c. and 80° c. and preferably at 70° c.
    • 离子源,质谱仪和提高用于质谱仪的离子源的性能的方法。 离子源具有壳体,其包括限定腔室的离子源外壳和远离腔室的外盖。 在离子源外壳和外盖之间提供流体流动通道。 本发明的方法包括向离子源供应以容纳流经流体通道的调节流体,以将离子源外壳保持在基本上在60℃之间的预定温度范围内。 和80℃。 优选为70℃。
    • 50. 发明申请
    • VACUUM ANALYZER
    • 真空分析仪
    • US20130134306A1
    • 2013-05-30
    • US13813875
    • 2011-07-19
    • Tomohito Nakano
    • Tomohito Nakano
    • H01J49/24
    • H01J49/24H01J49/005
    • A vacuum analyzer including a vacuum reaction chamber; a gas source; a flow rate-restricting resistance tube connected to the reaction chamber; a pressure detection device disposed upstream from the flow rate-restricting resistance tube; a flow rate adjustment for adjusting the amount of gas exiting the flow rate-restricting resistance tube so that the detected value from the pressure detection device reaches a prescribed value; a split flow path that is provided with a splitter resistance tube and divides the gas at a location between the flow rate adjustment and the pressure detection device; a passage open to the atmosphere which divides the gas flowing from upstream at a location between the flow rate adjustment and the pressure detection device and releases the divided gas to the atmosphere; and a valve provided in the passage open to the atmosphere. Therein, the split flow path is connected immediately downstream from the valve.
    • 一种真空分析器,包括真空反应室; 气源; 连接到反应室的流量限制电阻管; 压力检测装置,其设置在所述流量限制电阻管的上游; 用于调节离开流量限制电阻管的气体量使得来自压力检测装置的检测值达到规定值的流量调节; 分流流路,其设​​置有分流器阻力管,并且在流量调节和压力检测装置之间的位置分割气体; 一个通向大气的通道,其分隔在流量调节和压力检测装置之间的位置处从上游流动的气体,并将分解的气体释放到大气中; 以及设置在通向大气中的通道中的阀。 其中,分流流路直接连接在阀的下游。