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1. 发明申请

US20130015348A1 CURVED HEATED ION TRANSFER OPTICS 有权
标题翻译：弯曲加热离子转移光学
公开(公告)号：US20130015348A1
公开(公告)日：2013-01-17
申请号：US13370513
申请日：2012-02-10
申请人： Stephen ZANON , Roy P. MOELLER , Urs STEINER , Felician MUNTEAN
发明人： Stephen ZANON , Roy P. MOELLER , Urs STEINER , Felician MUNTEAN
IPC分类号： H01J49/26 , H01R43/00
CPC分类号： H01J37/04 , H01J49/0468 , H01J49/063 , H01J49/068 , H01J2237/053 , H01J2237/057 , H01J2237/1516
摘要： An ion optics assembly is formed by four quarter-circular profile elements, all of which are attach to the same reference plate. Consequently, all four elements remain aligned to the same reference plate. The four elements form a quarter-circular channel with quarter-circular quad electrodes. The quad electrodes receive electrical potential to form the field required to focus and maintain the ions at the center of the channel. Quarter-circular insulators are provided on all sides of the channel so as to seal the channel over its length from the interior of the mass spectrometer. A heater is provided at the entrance to the ion transfer optics, to prevent accumulation of ions on the poles. A thermal break is provided in the quad, so as to enable maintaining the front of the quad heated and the rest of the quad cooler.
摘要翻译：离子光学组件由四个四分之一圆形的轮廓元件形成，所有元件都附着在相同的参考板上。因此，所有四个元件保持与相同的参考板对准。四个元件形成四分之一圆形四通道四通道。四极电极接收电势以形成将离子聚焦并保持在通道中心所需的场。在通道的所有侧面都设有四分之一圆形的绝缘体，以便从质谱仪的内部将通道密封在其长度上。在离子转移光学器件的入口处设置加热器，以防止离子在极上的积聚。在四边形中提供热断裂，以便能够保持四边形的前部被加热并且四分之一冷却器的其余部分。

2. 发明授权

US08779353B2 Ion guide and electrode for its assembly 有权
标题翻译：离子导向器和电极组装
公开(公告)号：US08779353B2
公开(公告)日：2014-07-15
申请号：US13347754
申请日：2012-01-11
申请人： Stephen Zanon , Maurizio A. Splendore
发明人： Stephen Zanon , Maurizio A. Splendore
IPC分类号： H01J3/14 , B01D59/44
CPC分类号： H01J49/065 , H01J49/066
摘要： An ion guide that transports ions from an ion source at generally a high-pressure level to a mass analyzer at generally a low-pressure level has a plurality of identical electrodes fabricated with protruding elements that forming an ion tunnel or an ion funnel, when the electrodes are assembled around a common longitudinal axis. The protruding elements allow the generation of the radio frequency field necessary to radially confine ions. Each electrode may be machined from a solid block of conductive material, such as metal. The disclosed arrangement greatly simplifies the manufacturing process, reducing cost, and improving robustness and reliability of the ion guide itself.
摘要翻译：将离子通常以高压水平传输到质量分析器的离子导向器通常在低压水平下具有多个相同的电极，该电极用形成离子通道或离子漏斗的突出元件制成，电极围绕共同的纵向轴线组装。突出元件允许产生径向限制离子所需的射频场。每个电极可以由诸如金属的导电材料的固体块来加工。所公开的装置大大简化了制造过程，降低了成本，提高了离子导向器本身的鲁棒性和可靠性。

3. 发明申请

US20140061500A1 ATMOSPHERIC PRESSURE ION SOURCE WITH EXHAUST SYSTEM 有权
标题翻译：大气压离子源与排气系统
公开(公告)号：US20140061500A1
公开(公告)日：2014-03-06
申请号：US13602249
申请日：2012-09-03
申请人： Zicheng YANG , Roy P. MOELLER , Stephen ZANON
发明人： Zicheng YANG , Roy P. MOELLER , Stephen ZANON
IPC分类号： H01J27/02 , H01J27/24
CPC分类号： H01J49/044 , H01J49/165 , H01J49/168 , H01J49/24
摘要： An atmospheric pressure ion source, employing the principle of electrospray ionization, chemical ionization, or photo-ionization, comprises a spray probe for spraying a liquid into an ionization chamber and has an exhaust port through which residual spray mist and waste gas, such as evaporated solvent, are extracted. The ion source further comprises an exhaust system comprising a conduit which is connected to the exhaust port. The conduit has a transition from a first cross-section to a second cross section at a point downstream of the exhaust port wherein the second cross section is reduced in relation to the first cross section. Gas is injected via a gas injector into the conduit in a region of the transition to create a low pressure region that removes unwanted material from the chamber.
摘要翻译：使用电喷雾电离，化学电离或光电离原理的大气压离子源包括用于将液体喷射到电离室中的喷射探针，并具有排气口，残留的喷雾和废气如蒸发溶剂，萃取。离子源还包括排气系统，其包括连接到排气口的导管。导管在排气口下游的点处具有从第一横截面到第二横截面的过渡，其中第二横截面相对于第一横截面减小。气体通过气体注入器在过渡区域中被注入导管，以产生从腔室去除不需要的材料的低压区域。

4. 发明授权

US07338249B1 Sample plate gripping mechanism 失效
标题翻译：样品盘夹持机构
公开(公告)号：US07338249B1
公开(公告)日：2008-03-04
申请号：US11171674
申请日：2005-06-30
申请人： Stephen Zanon
发明人： Stephen Zanon
IPC分类号： B25J15/00 , H01J49/00
CPC分类号： G01N35/028 , B01L9/523 , B01L2300/0829 , G01N2035/042
摘要： An apparatus for releasably gripping a sample plate for use with a mass spectrometer has been developed, the sample plate having substantially parallel faces and a peripheral surface. The apparatus comprises a planar member and first and second guiding structures. The second guiding structure comprises a biasing mechanism which when activiated, provides a force that forces the second guiding structure towards the peripheral surface of the sample plate such that the sample plate is retained by the apparatus. Utilization of the configuration reduces frictional point contact thus reduces localized stress point resulting in yielding the surface material thus in effect guarding both sample plate and first guiding means from galling and/or reducing any type of material removal when gripping a sample plate, or releasing a sample plate.
摘要翻译：已经开发了用于可释放地夹持用于质谱仪的样品板的装置，样品板具有基本上平行的面和周边表面。该装置包括平面构件和第一和第二引导结构。第二引导结构包括偏置机构，当被激活时，偏置机构提供迫使第二引导结构朝向样品板的外周表面的力，使得样品板被设备保持。该构造的利用减少摩擦点接触，从而减少局部应力点，从而导致产生表面材料，从而实际上防止样品板和第一引导装置在夹持样品板时磨损和/或减少任何类型的材料去除，或释放样板。

5. 发明授权

US07282707B1 Method and apparatus for handling a sample plate for use in mass analysis 失效
标题翻译：用于处理用于质量分析的样品板的方法和装置
公开(公告)号：US07282707B1
公开(公告)日：2007-10-16
申请号：US11171907
申请日：2005-06-30
申请人： Stephen Zanon
发明人： Stephen Zanon
IPC分类号： H01J49/04
CPC分类号： H01J49/0409
摘要： A new sample plate handling apparatus for use with mass analysis, and methods for use the same have been developed. The sampling plate handling apparatus comprises a sample plate receiver which receives the sample plate in a first plane, a rotating device for rotating the sample plate from the first plane to a second plane, and a relocation device that relocates the sample plate in the second plane such that one of the samples on the sample plate is in the position desired for analysis by the mass analyzer. In one implementation, the relocation device can relocate the sample plate such that a beam of radiation that irradiates a sample on the sample plate emanates ionized particles that are substantially aligned with ion transfer optics of the mass analyzer.
摘要翻译：已经开发了用于质量分析的新的样品板处理装置及其使用方法。采样板处理装置包括在第一平面中接收样品板的样品板接收器，用于将样品板从第一平面旋转到第二平面的旋转装置，以及将样品板重新定位在第二平面中的重新定位装置使得样品板上的样品之一处于质量分析器所需的分析位置。在一个实施方案中，重新定位装置可以重新定位样品板，使得照射样品板上的样品的辐射束发射基本上与质量分析器的离子转移光学元件对准的离子化颗粒。

6. 发明授权

US08492713B2 Multipole assembly and method for its fabrication 有权
标题翻译：多极组件及其制造方法
公开(公告)号：US08492713B2
公开(公告)日：2013-07-23
申请号：US13406651
申请日：2012-02-28
申请人： Urs Steiner , Roy P Moeller , Stephen Zanon
发明人： Urs Steiner , Roy P Moeller , Stephen Zanon
IPC分类号： H01J49/42 , H01J49/34 , H01J49/06
CPC分类号： H01J49/4255 , H01J49/063 , H01J49/068 , Y10T156/10 , Y10T156/1052
摘要： A multipole rod assembly, such as used as mass analyzer, is fabricated using rods adhesively attached to shoes, which are then attached to isolation rings. A fixture is used in conjunction with precision-made spacers to precisely assemble the ion mass analyzer. The rods and shoes can be made of metal, while the isolation rings are preferably made of insulator, such as ceramic. The shoes and isolation rings need not be made to high precision, as the spacer ensures high accuracy in alignment and symmetry of the rods. Consequently, the rods are the only precision machined parts in the ion mass analyzer assembly.
摘要翻译：诸如用作质量分析器的多极杆组件使用粘附在鞋上的杆制造，然后将其连接到隔离环。固定装置与精密隔垫一起使用，以精确组装离子质量分析仪。杆和鞋可以由金属制成，而隔离环优选地由诸如陶瓷的绝缘体制成。鞋和隔离环不需要高精度，因为间隔物确保杆的对准和对称性的高精度。因此，这些棒是离子质量分析器组件中唯一的精密加工零件。

7. 发明申请

US20130175441A1 ION GUIDE AND ELECTRODE FOR ITS ASSEMBLY 有权
标题翻译：离子导管及其组件电极
公开(公告)号：US20130175441A1
公开(公告)日：2013-07-11
申请号：US13347754
申请日：2012-01-11
申请人： Stephen ZANON , Maurizio A. SPLENDORE
发明人： Stephen ZANON , Maurizio A. SPLENDORE
IPC分类号： H01J49/36
CPC分类号： H01J49/065 , H01J49/066
摘要： An ion guide that transports ions from an ion source at generally a high-pressure level to a mass analyzer at generally a low-pressure level has a plurality of identical electrodes fabricated with protruding elements that forming an ion tunnel or an ion funnel, when the electrodes are assembled around a common longitudinal axis. The protruding elements allow the generation of the radio frequency field necessary to radially confine ions. Each electrode may be machined from a solid block of conductive material, such as metal. The disclosed arrangement greatly simplifies the manufacturing process, reducing cost, and improving robustness and reliability of the ion guide itself.
摘要翻译：将离子通常以高压水平传输到质量分析器的离子导向器通常在低压水平下具有多个相同的电极，该电极用形成离子通道或离子漏斗的突出元件制成，电极围绕共同的纵向轴线组装。突出元件允许产生径向限制离子所需的射频场。每个电极可以由诸如金属的导电材料的固体块来加工。所公开的装置大大简化了制造过程，降低了成本，提高了离子导向器本身的鲁棒性和可靠性。

8. 发明申请

US20130015341A1 MULTIPOLE ASSEMBLY AND METHOD FOR ITS FABRICATION 有权
标题翻译：多组件组装及其制造方法
公开(公告)号：US20130015341A1
公开(公告)日：2013-01-17
申请号：US13406651
申请日：2012-02-28
申请人： Urs STEINER , Roy P. MOELLER , Stephen ZANON
发明人： Urs STEINER , Roy P. MOELLER , Stephen ZANON
IPC分类号： H01J49/02 , B32B37/02 , B32B38/04 , B32B37/12
CPC分类号： H01J49/4255 , H01J49/063 , H01J49/068 , Y10T156/10 , Y10T156/1052
摘要： A multipole rod assembly, such as used as mass analyzer, is fabricated using rods adhesively attached to shoes, which are then attached to isolation rings. A fixture is used in conjunction with precision-made spacers to precisely assemble the ion mass analyzer. The rods and shoes can be made of metal, while the isolation rings are preferably made of insulator, such as ceramic. The shoes and isolation rings need not be made to high precision, as the spacer ensures high accuracy in alignment and symmetry of the rods. Consequently, the rods are the only precision machined parts in the ion mass analyzer assembly.
摘要翻译：诸如用作质量分析器的多极杆组件使用粘附在鞋上的杆制造，然后将其连接到隔离环。固定装置与精密隔垫一起使用，以精确组装离子质量分析仪。杆和鞋可以由金属制成，而隔离环优选地由诸如陶瓷的绝缘体制成。鞋和隔离环不需要高精度，因为间隔物确保杆的对准和对称性的高精度。因此，这些棒是离子质量分析器组件中唯一的精密加工零件。

9. 发明授权

US08841607B2 Atmospheric pressure ion source with exhaust system 有权
标题翻译：带排气系统的大气压离子源
公开(公告)号：US08841607B2
公开(公告)日：2014-09-23
申请号：US13602249
申请日：2012-09-03
申请人： Zicheng Yang , Roy P Moeller , Stephen Zanon
发明人： Zicheng Yang , Roy P Moeller , Stephen Zanon
IPC分类号： H01J49/26
CPC分类号： H01J49/044 , H01J49/165 , H01J49/168 , H01J49/24
摘要： An atmospheric pressure ion source, employing the principle of electrospray ionization, chemical ionization, or photo-ionization, comprises a spray probe for spraying a liquid into an ionization chamber and has an exhaust port through which residual spray mist and waste gas, such as evaporated solvent, are extracted. The ion source further comprises an exhaust system comprising a conduit which is connected to the exhaust port. The conduit has a transition from a first cross-section to a second cross section at a point downstream of the exhaust port wherein the second cross section is reduced in relation to the first cross section. Gas is injected via a gas injector into the conduit in a region of the transition to create a low pressure region that removes unwanted material from the chamber.
摘要翻译：使用电喷雾电离，化学电离或光电离原理的大气压离子源包括用于将液体喷射到电离室中的喷射探针，并具有排气口，残留的喷雾和废气如蒸发溶剂，萃取。离子源还包括排气系统，其包括连接到排气口的导管。导管在排气口下游的点处具有从第一横截面到第二横截面的过渡，其中第二横截面相对于第一横截面减小。气体通过气体注入器在过渡区域中被注入导管，以产生从腔室去除不需要的材料的低压区域。

10. 发明授权

US08680462B2 Curved heated ion transfer optics 有权
标题翻译：弯曲加热离子转移光学
公开(公告)号：US08680462B2
公开(公告)日：2014-03-25
申请号：US13370513
申请日：2012-02-10
申请人： Stephen Zanon , Roy P Moeller , Urs Steiner , Felician Muntean
发明人： Stephen Zanon , Roy P Moeller , Urs Steiner , Felician Muntean
IPC分类号： H01J49/06
CPC分类号： H01J37/04 , H01J49/0468 , H01J49/063 , H01J49/068 , H01J2237/053 , H01J2237/057 , H01J2237/1516
摘要： An ion optics assembly is formed by four quarter-circular profile elements, all of which are attach to the same reference plate. Consequently, all four elements remain aligned to the same reference plate. The four elements form a quarter-circular channel with quarter-circular quad electrodes. The quad electrodes receive electrical potential to form the field required to focus and maintain the ions at the center of the channel. Quarter-circular insulators are provided on all sides of the channel so as to seal the channel over its length from the interior of the mass spectrometer. A heater is provided at the entrance to the ion transfer optics, to prevent accumulation of ions on the poles. A thermal break is provided in the quad, so as to enable maintaining the front of the quad heated and the rest of the quad cooler.
摘要翻译：离子光学组件由四个四分之一圆形的轮廓元件形成，所有元件都附着在相同的参考板上。因此，所有四个元件保持与相同的参考板对准。四个元件形成四分之一圆形四通道四通道。四极电极接收电势以形成将离子聚焦并保持在通道中心所需的场。在通道的所有侧面都设有四分之一圆形的绝缘体，以便从质谱仪的内部将通道密封在其长度上。在离子转移光学器件的入口处设置加热器，以防止离子在极上的积聚。在四边形中提供热断裂，以便能够保持四边形的前部被加热并且四分之一冷却器的其余部分。

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