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41. 发明申请

US20120106691A1 Method and System for Radioisotope Generation 失效
标题翻译：放射性同位素产生方法与系统
公开(公告)号：US20120106691A1
公开(公告)日：2012-05-03
申请号：US12939081
申请日：2010-11-03
申请人： James J. Toth , Chuck Z. Soderquist , Lawrence R. Greenwood , Shas V. Mattigod , Glen E. Fryxell , Matthew J. O'Hara
发明人： James J. Toth , Chuck Z. Soderquist , Lawrence R. Greenwood , Shas V. Mattigod , Glen E. Fryxell , Matthew J. O'Hara
IPC分类号： G21G1/00
CPC分类号： G21G1/0005 , G21G1/001 , G21G2001/0042
摘要： A system and a process for producing selected isotopic daughter products from parent materials characterized by the steps of loading the parent material upon a sorbent having a functional group configured to selectively bind the parent material under designated conditions, generating the selected isotopic daughter products, and eluting said selected isotopic daughter products from the sorbent. In one embodiment, the process also includes the step of passing an eluent formed by the elution step through a second sorbent material that is configured to remove a preselected material from said eluent. In some applications a passage of the material through a third sorbent material after passage through the second sorbent material is also performed.
摘要翻译：一种用于从母体材料生产选择的同位素子产物的系统和方法，其特征在于以下步骤：将母体材料加载到具有官能团的吸附剂上，所述吸附剂配置成在指定条件下选择性地结合母体材料，产生所选择的同位素子产物，所述选择的来自吸附剂的同位素子产物。在一个实施方案中，该方法还包括将通过洗脱步骤形成的洗脱液通过第二吸附剂材料的步骤，该第二吸附剂材料被配置为从所述洗脱液中除去预选物质。在一些应用中，还进行通过第二吸附剂材料之后材料通过第三吸着剂材料的通道。

42. 发明申请

US20110280357A1 Tc-99m PRODUCED BY PROTON IRRADIATION OF A FLUID TARGET SYSTEM 有权
标题翻译： Tc-99m由流体目标系统的原子辐照产生
公开(公告)号：US20110280357A1
公开(公告)日：2011-11-17
申请号：US13106634
申请日：2011-05-12
申请人： Nigel R. Stevenson
发明人： Nigel R. Stevenson
IPC分类号： G21G1/10
CPC分类号： G21G1/001 , G21G1/10 , G21G2001/0042
摘要： Methods for producing Tc-99m radioisotope by proton irradiation of a fluid target matrix. A method of producing Tc-99m includes irradiating a fluid target matrix comprising Mo-100 with a proton beam to transform at least a portion of Mo-100 to Tc-99m. Optionally, the fluid target matrix further includes at least one of O-18, O-16, or N-14, which upon exposure to the proton beam concurrently transform at least a portion of O-18 to F-18, at least a portion of O-16 to N-13, at least a portion of the O-16 to O-15, or at least a portion of N-14 to C-11. The method further includes isolating Tc-99m and optionally at least one of F-18, N-13, O-15, or C-11 from the irradiated fluid target matrix. An additional source of Tc-99m is available from the decay of Mo-99 that is co-produced from the Mo-100 during irradiation with the proton beam.
摘要翻译：通过流体靶基质的质子照射来生产Tc-99m放射性同位素的方法。制备Tc-99m的方法包括用质子束照射包含Mo-100的流体靶基质以将至少一部分Mo-100转化为Tc-99m。任选地，流体目标基质还包括O-18，O-16或N-14中的至少一种，其在暴露于质子束时同时将至少一部分O-18转化为F-18，至少一种 O-16至N-13的部分，O-16至O-15的至少一部分，或N-14至C-11的至少一部分。该方法还包括从照射的流体靶基质中分离出Tc-99m和任选的F-18，N-13，O-15或C-11中的至少一种。从质子束照射期间Mo-100共同生产的Mo-99的衰变可获得额外的Tc-99m源。

43. 发明申请

US20110051873A1 METHOD FOR PRODUCING RADIOSTRONTIUM 有权
标题翻译：生产放射线谱的方法
公开(公告)号：US20110051873A1
公开(公告)日：2011-03-03
申请号：US12919527
申请日：2009-03-13
申请人： Boris Leonidovich Zhuikov , Stanislav Viktorovich Ermolaev , Vladimir Mikhailovich Kokhanyuk
发明人： Boris Leonidovich Zhuikov , Stanislav Viktorovich Ermolaev , Vladimir Mikhailovich Kokhanyuk
IPC分类号： G21G1/10
CPC分类号： G21G1/001 , G21G1/10 , G21G2001/0094
摘要： The invention relates to producing radiostrontium. The aim of the invention is to release radiostrontium from a large mass of liquid metal rubidium, thereby making it possible to increase the efficiency of radiostrontium production and simplify the production process. Sorption is carried out directly on the inner shell of a target at a temperature of 275-350° C., or by extracting radiostrontium from circulating rubidium by sorption on the heated surface of a trap at a temperature of 220-350° C., or by filtering liquid rubidium through a filtering element made of a porous material resistant to liquid rubidium.
摘要翻译：本发明涉及生产射电天文。本发明的目的是从大量的液态金属铷释放放射性锶，从而可以提高射出锶的生产效率并简化生产过程。在275-350℃的温度下直接在靶的内壳上进行吸附，或者通过在220-350℃的温度下通过吸附在捕获器的加热表面上从循环的铷中提取射线辐射，或者通过由耐液体铷的多孔材料制成的过滤元件过滤液体铷。

44. 发明授权

US07858374B2 Method and device for reducing positron emitting isotope labeled carbon dioxide to positron emitter isotope labeled carbon monoxide via metal oxide 有权
标题翻译：用于通过金属氧化物将正电子发射同位素标记的二氧化碳还原成正电子发射极同位素标记的一氧化碳的方法和装置
公开(公告)号：US07858374B2
公开(公告)日：2010-12-28
申请号：US11803388
申请日：2007-05-14
申请人： Charles Russell Buchanan , Andrew C. Williamson
发明人： Charles Russell Buchanan , Andrew C. Williamson
IPC分类号： G01N23/00 , C12M1/00
CPC分类号： G21G1/001 , G21G2001/0094
摘要： A method and device for reducing positron emitter isotope labeled CO2 to positron emitter isotope labeled CO generally includes introducing a volume of positron emitter isotope labeled CO2 into a first heated reaction vessel comprising a metal oxide, such as Iron (II) Oxide such that the CO2 is reduced to CO upon contact with the Iron (II) Oxide. The volume is then transferred to a second reaction vessel to remove any un-reacted CO2, preferably, via a soda-lime trap. The volume is then transferred to a target, e.g., a storage vessel or subject. The CO2 includes one of [11C] or [15O]. The first reaction vessel is, preferably, heated to a temperature of between 900 and 1000° C., and more preferably, to between 925 and 975° C., and even more preferably, to approximately 950° C. Preferably, the Iron (II) Oxide powdered and has a particle size of about −10 mesh.
摘要翻译：用于将正电子发射极同位素标记的CO 2还原为正电子发射极同位素标记的CO的方法和装置通常包括将一定体积的正电子发射极同位素标记的CO 2引入到包含金属氧化物如氧化铁（II）的第一加热反应容器中，使得CO 2 在与氧化铁（II）接触时被还原成CO。然后将体积转移到第二反应容器中以除去任何未反应的CO 2，优选通过碱石灰捕集器。然后将体积转移到靶，例如储存容器或受试者。二氧化碳包括[11C]或[150]之一。优选地，将第一反应容器加热至900至1000℃，更优选加热至925至975℃，甚至更优选至约950℃。优选地，铁（ II）氧化物粉末，粒径约为-10目。

45. 发明申请

US20100312039A1 INFUSION SYSTEM CONFIGURATIONS 有权
标题翻译：灌注系统配置
公开(公告)号：US20100312039A1
公开(公告)日：2010-12-09
申请号：US12865924
申请日：2009-06-11
申请人： Charles R. Quirico , Ernest Balestracci , Rolf E. Swenson , Daniel D. Darst , Eric J. Krause , Vishal N. Lokhande , Jacob S. Childs
发明人： Charles R. Quirico , Ernest Balestracci , Rolf E. Swenson , Daniel D. Darst , Eric J. Krause , Vishal N. Lokhande , Jacob S. Childs
IPC分类号： A61M36/00
CPC分类号： A61M5/007 , A61B6/037 , A61B6/107 , A61B6/481 , A61B6/507 , A61B50/13 , A61B90/39 , A61B2050/105 , A61B2090/392 , A61K51/00 , A61M5/14 , A61M5/1409 , A61M5/142 , A61M5/1452 , A61M5/158 , A61M5/16854 , A61M5/16881 , A61M5/365 , A61M2005/1403 , A61M2205/18 , A61M2205/276 , A61M2205/3375 , A61M2205/50 , A61M2205/505 , A61M2205/52 , A61M2205/584 , A61M2205/587 , A61M2205/6009 , A61M2205/6054 , A61M2205/6072 , A61M2205/70 , A61M2205/75 , A61M2209/084 , A61N5/1001 , A61N5/1007 , A61N5/1075 , A61N2005/1021 , A61N2005/1022 , A61N2005/1074 , A61N2005/1094 , B62B3/005 , G06F19/00 , G06F19/3468 , G06F21/31 , G21F3/00 , G21F7/00 , G21G1/0005 , G21G1/001 , G21G4/08 , G21G2001/0031
摘要： Infusion system configurations and assemblies facilitate routing of infusion circuit tubing lines. Tubing lines are routed into and out from compartments of a shielding assembly for the infusion system, at locations which prevent kinking and/or crushing of the lines, and/or provide for ease in assembling the circuit. A plurality of the lines may be held together by a support frame to form a disposable infusion circuit subassembly, that can further facilitate routing of the lines.
摘要翻译：输液系统配置和组件便于输注电路管线的布线。在防止线路扭结和/或破碎的位置处和/或为组装电路提供便利的位置，将管道线路输入和输出用于输注系统的屏蔽组件的隔间。多个线可以由支撑框架保持在一起以形成一次性输注电路子组件，其可以进一步促进线路的布线。

46. 发明授权

US07728310B2 Method for the chemical separation of GE-68 from its daughter Ga-68 失效
标题翻译： GE-68与其女儿Ga-68化学分离的方法
公开(公告)号：US07728310B2
公开(公告)日：2010-06-01
申请号：US12151865
申请日：2008-05-08
申请人： Jonathan M. Fitzsimmons , Robert W. Atcher
发明人： Jonathan M. Fitzsimmons , Robert W. Atcher
IPC分类号： B01D59/44
CPC分类号： G21G1/001 , G21G2001/0021
摘要： The present invention is directed to a generator apparatus for separating a daughter gallium-68 radioisotope substantially free of impurities from a parent gernanium-68 radioisotope, including a first resin-containing column containing parent gernanium-68 radioisotope and daughter gallium-68 radioisotope, a source of first eluent connected to said first resin-containing column for separating daughter gallium-68 radioisotope from the first resin-containing column, said first eluent including citrate whereby the separated gallium is in the form of gallium citrate, a mixing space connected to said first resin-containing column for admixing a source of hydrochloric acid with said separated gallium citrate whereby gallium citrate is converted to gallium tetrachloride, a second resin-containing column for retention of gallium-68 tetrachloride, and, a source of second eluent connected to said second resin-containing column for eluting the daughter gallium-68 radioisotope from said second resin-containing column.
摘要翻译：本发明涉及一种用于将母体锗-68放射性同位素基本上不含杂质的子镓-68放射性同位素分离的发生器装置，包括含有母体锗-68放射性同位素和子镓68放射性同位素的第一含树脂柱，连接到所述第一含树脂柱的第一洗脱液源，用于从第一含树脂柱中分离子镓-68放射性同位素，所述第一洗脱液包括柠檬酸盐，由此分离的镓是柠檬酸镓的形式，与所述第一含树脂柱连接的混合空间第一含树脂柱，用于将盐酸源与所述分离的柠檬酸镓混合，由此将柠檬酸镓转化为四氯化镓，用于保留四氯化镓的第二含树脂的塔，以及连接到所述的四氯化镓的第二洗脱源第二树脂柱，用于从所述第二树脂洗脱子镓-68放射性同位素含n柱。

47. 发明授权

US07491345B2 Extraction mixture for recovery of actinide elements from acidic solutions 失效
标题翻译：萃取混合物，用于从酸性溶液中回收锕系元素
公开(公告)号：US07491345B2
公开(公告)日：2009-02-17
申请号：US11097257
申请日：2005-04-04
申请人： Masaki Ozawa , Vasily Alexandrovich Babain , Yury Stepanovich Fedorov , Andey Yurievich Shadrin , Valery Nikolaevich Romanovsky , Igor Valentinovich Smirnov , Boris Yakovlevich Zilberman
发明人： Masaki Ozawa , Vasily Alexandrovich Babain , Yury Stepanovich Fedorov , Andey Yurievich Shadrin , Valery Nikolaevich Romanovsky , Igor Valentinovich Smirnov , Boris Yakovlevich Zilberman
IPC分类号： B01D11/00
CPC分类号： C01G56/00 , C01G56/001 , C22B3/0071 , C22B3/0078 , C22B3/0095 , G21F9/06 , G21F9/12 , G21G1/001 , Y02P10/234 , Y10S423/14
摘要： Extraction mixture capable of recovering actinide elements such as U, Pu and transplutonium elements from radioactive liquid waste in reprocessing of spent nuclear fuel. One embodiment of the extraction mixture includes a solution of bidentate organophosphorus extractant, dihexyl-N, N-diethylcarbamoyl phosphonate in a polar diluent, wherein bis-tetrafluoropropyl ether of diethylene glycol is used as the polar diluent at the following ratio of components: 0.1-1.2 M/L of bidentate extractant and the rest of diluent. Another embodiment of the extraction mixture includes a solution of bidentate organophosphorus extractant, phenyloctyl-N,N-diisobutylcarbamoylphosphine oxide in a polar diluent, wherein a mixture of metanitrobenzotrifluoride with trialkylphosphate is used as the polar diluent at the following ratio of components: 0.1-1.2 M/L of bidentate extractant, 0.3-1.1 M/L of TBP, and the rest of MNBTF.
摘要翻译：萃取混合物能够从废弃核燃料的后处理中回收放射性废液中的锕系元素如U，Pu和钚元素。提取混合物的一个实施方案包括二极有机磷萃取剂，二己基-N，N-二乙基氨基甲酰基膦酸酯在极性稀释剂中的溶液，其中二乙二醇的双 - 四氟丙醚以下列比例的比例用作极性稀释剂：0.1- 1.2 M / L二齿萃取剂和其余稀释剂。萃取混合物的另一个实施方案包括二极有机磷萃取剂，苯基辛基-N，N-二异丁基氨基甲酰氧基氧化物在极性稀释剂中的溶液，其中以三苯基三氟甲烷与磷酸三烷基酯的混合物以下列比例的比例用作极性稀释剂：0.1-1.2 M / L二齿提取剂，0.3-1.1 M / L TBP，其余MNBTF。

48. 发明申请

US20070207075A1 Separation of germanium-68 from gallium-68 审中-公开
标题翻译：锗-68与镓-68的分离
公开(公告)号：US20070207075A1
公开(公告)日：2007-09-06
申请号：US11367572
申请日：2006-03-03
申请人： Michael Fassbender
发明人： Michael Fassbender
IPC分类号： C01F13/00
CPC分类号： B01J41/04 , G21G1/001 , G21G2001/0094
摘要： A method for separating germanium-68 from gallium-68 using an anion exchange resin and a chelating/complexing agent containing a plurality of carboxylic acid groups and at least three carbon atoms to the first solution is disclosed together with a generator apparatus for providing a source of gallium-68.
摘要翻译：公开了一种用于使用阴离子交换树脂和含有多个羧酸基团和至少三个碳原子的螯合/络合剂将锗-68从镓-68分离到第一溶液的方法，用于提供源的镓-68。

49. 发明授权

US3226298A Process for making high purity radioactive iodine-131 失效
标题翻译：制备高纯度放射性碘-131的方法
公开(公告)号：US3226298A
公开(公告)日：1965-12-28
申请号：US31853163
申请日：1963-10-24
申请人： UNION CARBIDE CORP
发明人： GEMMILL WAYNE J
IPC分类号： C01B7/14
CPC分类号： G21G1/02 , C01B7/14 , G21G1/001 , G21G2001/0063

50. 发明授权

US2571965A Process for production of radioactive iron 失效
标题翻译：放射性铁生产工艺
公开(公告)号：US2571965A
公开(公告)日：1951-10-16
申请号：US18365750
申请日：1950-09-07
申请人： SWARTOUT JOHN A
发明人： SWARTOUT JOHN A
IPC分类号： C01G49/00
CPC分类号： G21G1/001 , C01G49/00 , G21G1/06 , G21G2001/0094

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