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41. 发明授权

US07297359B2 Process for the preparation of a foamed product and products obtainable by this process 有权
标题翻译：用于制备可通过该方法获得的发泡产品和产品的方法
公开(公告)号：US07297359B2
公开(公告)日：2007-11-20
申请号：US10471482
申请日：2002-02-06
申请人： Yvonne Evelien Bruggeman , Peter Ravestein
发明人： Yvonne Evelien Bruggeman , Peter Ravestein
IPC分类号： A23L1/0524 , A23G9/20
CPC分类号： A23G9/34 , A23G9/20 , A23G9/327 , A23G9/46 , A23L29/231 , A23P30/40 , A23V2002/00 , C12Y110/03001 , C12Y110/03002 , C12Y111/01007 , A23V2250/54252 , A23V2250/5072 , A23V2250/194 , A23V2250/182 , A23V2250/192
摘要： Foamed products based on an aqueous composition comprising an oxidised ferulyated polymer are stable both during storage and after freezing and subsequent storage. A process for preparing these products is provided.
摘要翻译：基于包含氧化的氧化聚合物的水性组合物的发泡产品在储存期间和在冷冻和随后的储存后都是稳定的。提供了制备这些产品的方法。

42. 发明授权

US07087426B2 Materials and methods for the modification of plant lignin content 失效
公开(公告)号：US07087426B2
公开(公告)日：2006-08-08
申请号：US10174693
申请日：2002-06-18
申请人： Leonard N. Bloksberg , Ikka Havukkala
发明人： Leonard N. Bloksberg , Ikka Havukkala
IPC分类号： C12N15/00 , C12N15/09 , C12N5/04 , C12N5/10 , C07H21/04
CPC分类号： C12Y110/03001 , C12N9/0004 , C12N9/0006 , C12N9/0008 , C12N9/001 , C12N9/0059 , C12N9/0061 , C12N9/0065 , C12N9/0071 , C12N9/0083 , C12N9/1007 , C12N9/1011 , C12N9/1051 , C12N9/2422 , C12N9/2445 , C12N9/86 , C12N9/88 , C12N9/93 , C12N15/8255 , C12Y110/03002 , C12Y114/13011 , C12Y201/01006 , C12Y302/01001 , C12Y302/01021
摘要： Novel isolated polynucleotides and polypeptides associated with the lignin biosynthetic pathway are provided, together with genetic constructs including such sequences. Methods for the modulation of lignin content, lignin structure and lignin composition in target organisms are also disclosed, the methods comprising incorporating one or more of the polynucleotides of the present invention into the genome of a target organism.

43. 发明授权

US06899876B2 Compositions and methods relating to reduction of symptoms of autism 有权
标题翻译：与减少自闭症症状有关的组成和方法
公开(公告)号：US06899876B2
公开(公告)日：2005-05-31
申请号：US10313338
申请日：2002-12-06
申请人： Devin B. Houston
发明人： Devin B. Houston
IPC分类号： A61K38/00 , A61K38/48 , C12N9/02 , C12N9/48 , C12N9/62
CPC分类号： C12N9/48 , A61K38/4813 , C12N9/0059 , C12Y110/03001 , C12Y304/14005 , A61K2300/00
摘要： Methods and compositions that can reduce the symptoms of autism in a human patient comprising administering a physiologically effective amount of one or both of a purified casomorphin inhibitor selected from the group consisting of a casomorphinase and a casomorphin ligand, and a physiologically effective amount of a purified gluteomorphin inhibitor selected from the group consisting of a gluteomorphinase and a gluteomorphin ligand, to a human patient in sufficient quantities to reduce the effects of the autism. In some embodiments, the compositions and methods further comprise a physiologically effective amount of an enkephalin inhibitor, preferably an enkephalinase, and a physiologically effective amount of an endorphin inhibitor, preferably an endorphinase.
摘要翻译：可以减轻人类患者自闭症症状的方法和组合物，其包括给予生理学有效量的选自下列药物的一种或两种纯化的casomorphin抑制剂：胱天肽酶和casomorphin配体，以及生理有效量的纯化麝香草素抑制剂，选自糠醛吗啡酶和钆蓝霉素配体，以足够的量向人类患者减轻自闭症的作用。在一些实施方案中，组合物和方法还包含生理有效量的脑啡肽抑制剂，优选脑啡肽酶和生理有效量的内啡肽抑制剂，优选内啡肽。

44. 发明申请

US20050037462A1 GP75 as a tumor vaccine for melanoma 审中-公开
标题翻译： GP75作为黑色素瘤肿瘤疫苗
公开(公告)号：US20050037462A1
公开(公告)日：2005-02-17
申请号：US10877489
申请日：2004-06-25
申请人： Alan Houghton , Setaluri Vijayasaradhi
发明人： Alan Houghton , Setaluri Vijayasaradhi
IPC分类号： C12N15/11 , A61K31/65 , A61K35/36 , A61K38/00 , A61K39/00 , A61K48/00 , A61P35/00 , C07K14/47 , C12N9/02 , C12N15/09 , C12N15/12 , C12N15/53 , C12N15/63 , A61K38/27 , C07H21/04 , C07K7/08
CPC分类号： C12Y110/03001 , A61K38/00 , A61K39/00 , C07K14/47 , C12N9/0059 , C12N9/0071 , C12Y114/16002 , C12Y114/18001
摘要： The present invention provides an isolated nucleic acid molecule whose sequence encodes the amino acid sequence for gp75 or a fragment thereof. The present invention further provides an isolated cDNA molecule of the gp75 nucleic acid molecule or a fragment thereof and the amino acid sequence derived therefrom. This invention also provides vaccines for stimulating or enhancing in a subject to whom the vaccine is administered production of antibodies directed against gp75. This invention further provides methods using the vaccines of this invention for stimulating or enhancing production of antibodies against gp75 as well as for treating, preventing or delaying the recurrence of cancer.
摘要翻译：本发明提供了分离的核酸分子，其序列编码gp75的氨基酸序列或其片段。本发明还提供了gp75核酸分子或其片段的分离的cDNA分子和由其衍生的氨基酸序列。本发明还提供用于在施用疫苗的受试者中刺激或增强针对gp75的抗体产生的疫苗。本发明还提供了使用本发明的疫苗刺激或增强针对gp75的抗体的产生以及用于治疗，预防或延迟癌症复发的方法。

45. 发明授权

US06733776B1 Method for promoting hair growth 失效
标题翻译：促进头发生长的方法
公开(公告)号：US06733776B1
公开(公告)日：2004-05-11
申请号：US08859051
申请日：1997-05-20
申请人： Lingna Li , Valeryi Lishko
发明人： Lingna Li , Valeryi Lishko
IPC分类号： A61K9127
CPC分类号： C12Y110/03001 , A61K8/14 , A61K8/606 , A61K8/72 , A61K9/127 , A61K48/00 , A61Q5/10 , A61Q7/00 , C12N9/001 , C12N9/0059 , C12N9/0071 , C12N9/2471 , C12Y103/01022 , C12Y114/18001 , C12Y302/01023
摘要： The invention provides a method to provide hair growth by stimulating extrusion of hair from a hair follicle which employs a liposomal formulation of an active ingredient which stimulates extrusion when taken up by the hair follicles.
摘要翻译：本发明提供一种通过刺激来自毛囊的毛发的挤出来提供毛发生长的方法，所述毛囊采用活性成分的脂质体制剂，该活性成分在被毛囊吸收时刺激挤出。

46. 发明申请

US20040014700A1 Novel oligonucleotides and use of oligonucleotides modulating the expression of enzymes involved in the synthesis of melanic pigments, as depigmentation agents 有权
标题翻译：新型寡核苷酸和使用寡核苷酸调节涉及黑素色素合成的酶的表达，作为脱色素
公开(公告)号：US20040014700A1
公开(公告)日：2004-01-22
申请号：US10203398
申请日：2003-01-06
发明人： Robin Kurfurst , Regine Joly
IPC分类号： A61K048/00 , C12Q001/68 , C07H021/04
CPC分类号： C12N15/1137 , A61K8/606 , A61K38/00 , A61Q1/12 , A61Q5/08 , A61Q19/02 , C12N2310/3125 , C12N2310/315 , C12N2310/321 , C12N2310/345 , C12N2310/346 , C12Y110/03001 , C12N2310/3521 , C12N2310/3525
摘要： The present invention relates to novel oligonucleotide sequences and also to derivatives thereof. These novel oligonucleotide sequences are capable of hybridizing specifically with the gene or with a product of the gene encoding tyrosinase, or with the gene or a product of the gene encoding tyrosinase-related-protein 1 (TRP-1). The present invention also relates to the use of these novel oligonucleotide sequences as a depigmenting or bleaching agent in a cosmetic composition or in a dermatological composition.
摘要翻译：本发明涉及新的寡核苷酸序列及其衍生物。这些新型寡核苷酸序列能够与基因或与编码酪氨酸酶的基因的产物或编码酪氨酸酶相关蛋白1（TRP-1）的基因的基因或产物特异性杂交。本发明还涉及这些新型寡核苷酸序列在化妆品组合物或皮肤病学组合物中作为脱色或漂白剂的用途。

47. 发明授权

US06410718B1 Materials and methods for the modification of plant lignin content 失效
标题翻译：修饰植物木质素含量的材料和方法
公开(公告)号：US06410718B1
公开(公告)日：2002-06-25
申请号：US09615192
申请日：2000-07-12
申请人： Leonard N. Bloksberg , Ilkka Havukkala
发明人： Leonard N. Bloksberg , Ilkka Havukkala
IPC分类号： C07H2102
CPC分类号： C12Y110/03001 , C12N9/0004 , C12N9/0006 , C12N9/0008 , C12N9/001 , C12N9/0059 , C12N9/0061 , C12N9/0065 , C12N9/0071 , C12N9/0083 , C12N9/1007 , C12N9/1011 , C12N9/1051 , C12N9/2414 , C12N9/2422 , C12N9/2445 , C12N9/86 , C12N9/88 , C12N9/93 , C12N15/8255 , C12Y110/03002 , C12Y114/13011 , C12Y201/01006 , C12Y302/01001 , C12Y302/01021
摘要： Novel isolated polynucleotides and polypeptides associated with the lignin biosynthetic pathway are provided, together with constructs including such sequences. Methods for the modulation of lignin content, lignin structure and lignin composition in target organisms are also disclosed, the methods comprising incorporating one or more of the polynucleotides of the present invention into the genome of a target organism.
摘要翻译：提供了与木质素生物合成途径相关的新型分离的多核苷酸和多肽以及包括这些序列的构建体。还公开了调节靶生物体中木质素含量，木质素结构和木质素组成的方法，所述方法包括将一种或多种本发明的多核苷酸掺入目标生物体的基因组中。

48. 发明授权

US06168946A gp75 as a tumor vaccine for melanoma 失效
标题翻译： gp75作为黑色素瘤肿瘤疫苗
公开(公告)号：US06168946A
公开(公告)日：2001-01-02
申请号：US08409794
申请日：1995-03-24
申请人： Alan N. Houghton , Setaluri Vijayasaradhi
发明人： Alan N. Houghton , Setaluri Vijayasaradhi
IPC分类号： C12N1512
CPC分类号： C12Y110/03001 , A61K38/00 , A61K39/00 , C07K14/47 , C12N9/0059 , C12N9/0071 , C12Y114/16002 , C12Y114/18001
摘要： The present invention provides an isolated nucleic acid molecule whose sequence encodes the amino acid sequence for gp75 or a fragment thereof. The present invention further provides an isolated cDNA molecule of the gp75 nucleic acid molecule or a fragment thereof and the amino acid sequence derived therefrom. This invention also provides vaccines for stimulating or enhancing in a subject to whom the vaccine is administered production of antibodies directed against gp75. This invention further provides methods using the vaccines of this invention for stimulating or enhancing production of antibodies against gp75 as well as for treating, preventing or delaying the recurrence of cancer.
摘要翻译：本发明提供了分离的核酸分子，其序列编码gp75的氨基酸序列或其片段。本发明还提供了gp75核酸分子或其片段的分离的cDNA分子和由其衍生的氨基酸序列。本发明还提供用于在施用疫苗的受试者中刺激或增强针对gp75的抗体产生的疫苗。本发明还提供了使用本发明的疫苗刺激或增强针对gp75的抗体的产生以及用于治疗，预防或延迟癌症复发的方法。

49. 发明授权

US6160204A Polyphenol oxidase cDNA 失效
标题翻译：多酚氧化酶cDNA
公开(公告)号：US6160204A
公开(公告)日：2000-12-12
申请号：US481190
申请日：1995-06-07
申请人： John C. Steffens
发明人： John C. Steffens
IPC分类号： C12N9/02 , C12N15/82 , A01H5/00 , C12N5/04
CPC分类号： C12Y110/03001 , C12N9/0059 , C12N9/0071 , C12N15/8241 , C12Y114/18001
摘要： The present invention describes the cloning and sequencing of plant Polyphenol Oxidase (PPO) cDNAs which has subsequently permitted their use to genetically transform plants to achieve a variety of desired phenotypes.
摘要翻译：本发明描述了植物多酚氧化酶（PPO）cDNA的克隆和测序，其随后允许其用于遗传转化植物以实现各种期望的表型。

50. 发明授权

US5814495A Melanin production by streptomyces 失效
标题翻译：黑色素生成由链霉菌
公开(公告)号：US5814495A
公开(公告)日：1998-09-29
申请号：US404384
申请日：1995-03-14
申请人： Guy della-Cioppa , Stephen J. Garger, Jr. , Genadie G. Sverlow , Thomas H. Turpen , Laurence K. Grill , Miles R. Chedekal
发明人： Guy della-Cioppa , Stephen J. Garger, Jr. , Genadie G. Sverlow , Thomas H. Turpen , Laurence K. Grill , Miles R. Chedekal
IPC分类号： C07K2/00 , C07K14/36 , C12N9/02 , C12P17/00 , C12P17/14 , A61K7/44
CPC分类号： C12N9/0059 , C07K14/36 , C12N9/0071 , C12P17/00 , C12Y110/03001 , C12Y114/18001
摘要： The present invention is directed to a process for producing melanins, their precursors and their analoges, hereinafter referred to generically as melanins. According to the invention, melanins are produced in amounts greater than about 3.3 grams wet weight per liter of growth medium. The enhanced production of melanin can be achieved by manipulating the constituents of the growth medium, and/or attenuating fermentations conditions, and/or by genetically engineering microorganisms to produce melanins, and/or mutating the microorganisms.
摘要翻译：本发明涉及一种生产黑色素及其前体及其类似物的方法，以下通常称为黑色素。根据本发明，以每升生长培养基大于约3.3克湿重的量生产黑色素。可以通过操纵生长培养基的成分和/或减弱发酵条件和/或通过遗传工程微生物产生黑色素和/或使微生物变异来实现黑色素的增强生产。

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