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41. 发明授权

US09341622B2 Cellulose derivative fine particle, dispersion liquid thereof, dispersion body thereof and diagnostic reagent 有权
公开(公告)号：US09341622B2
公开(公告)日：2016-05-17
申请号：US14750970
申请日：2015-06-25
申请人： Asahi Kasei Fibers Corporation
发明人： Yoshiyuki Shiomi , Toshihiko Matsui , Masanori Doi
IPC分类号： G01N33/544 , G01N33/548 , C08B1/00 , C08B1/08 , C08B5/14 , C08B11/02 , C08B11/04 , C08B11/08 , C08B11/10 , C08B11/12 , C08B11/145 , C08B11/155 , C08B11/20 , C08B15/00 , C08B15/04 , C08B15/10 , C08B16/00 , C08J3/16 , C08L1/08 , C08L1/26 , C08L1/28
CPC分类号： G01N33/548 , C08B1/006 , C08B1/08 , C08B5/14 , C08B11/02 , C08B11/04 , C08B11/08 , C08B11/10 , C08B11/12 , C08B11/145 , C08B11/155 , C08B11/20 , C08B15/005 , C08B15/04 , C08B15/10 , C08B16/00 , C08J3/16 , C08J2301/28 , C08L1/08 , C08L1/26 , C08L1/28 , C08L1/282 , C08L1/284 , C08L1/286 , C08L1/288 , G01N2400/26 , Y10T428/2982
摘要： An object of the present invention is to provide a hydrophilic cellulose derivative fine particle having a small particle size, a dispersion liquid thereof and a dispersion body thereof; and provide a diagnostic reagent composed of the hydrophilic particle, which is excellent in storage stability and does not require excess components, such as an emulsifier or surfactant. The cellulose derivative fine particle of the present invention is a cellulose derivative fine particle comprising a cellulose derivative with a part of hydroxyl groups of cellulose being substituted with a substituent, wherein the average particle diameter is from 9 to 1,000 nm; and the diagnostic reagent of the present invention is a diagnostic reagent obtained by loading a substance differentially interacting with a test object substance on the above-described cellulose derivative fine particle.

42. 发明授权

US09096690B2 Cellulose derivative fine particle, dispersion liquid thereof, dispersion body thereof and diagnostic reagent 有权
标题翻译：纤维素衍生物微粒，分散液，分散体及诊断试剂
公开(公告)号：US09096690B2
公开(公告)日：2015-08-04
申请号：US12935246
申请日：2009-03-30
申请人： Yoshiyuki Shiomi , Toshihiko Matsui , Masanori Doi
发明人： Yoshiyuki Shiomi , Toshihiko Matsui , Masanori Doi
IPC分类号： G01N33/544 , C08B1/00 , C08B1/08 , C08B5/14 , C08B11/02 , C08B11/04 , C08B11/08 , C08B11/10 , C08B11/12 , C08B11/145 , C08B11/155 , C08B11/20 , C08B15/00 , C08B15/04 , C08B15/10 , C08B16/00 , C08J3/16 , C08L1/08 , C08L1/26 , C08L1/28 , G01N33/548
CPC分类号： G01N33/548 , C08B1/006 , C08B1/08 , C08B5/14 , C08B11/02 , C08B11/04 , C08B11/08 , C08B11/10 , C08B11/12 , C08B11/145 , C08B11/155 , C08B11/20 , C08B15/005 , C08B15/04 , C08B15/10 , C08B16/00 , C08J3/16 , C08J2301/28 , C08L1/08 , C08L1/26 , C08L1/28 , C08L1/282 , C08L1/284 , C08L1/286 , C08L1/288 , G01N2400/26 , Y10T428/2982
摘要： An object of the present invention is to provide a hydrophilic cellulose derivative fine particle having a small particle size, a dispersion liquid thereof and a dispersion body thereof; and provide a diagnostic reagent composed of the hydrophilic particle, which is excellent in storage stability and does not require excess components, such as an emulsifier or surfactant. The cellulose derivative fine particle of the present invention is a cellulose derivative fine particle comprising a cellulose derivative with a part of hydroxyl groups of cellulose being substituted with a substituent, wherein the average particle diameter is from 9 to 1,000 nm; and the diagnostic reagent of the present invention is a diagnostic reagent obtained by loading a substance differentially interacting with a test object substance on the above-described cellulose derivative fine particle.
摘要翻译：本发明的目的是提供一种具有小粒径的亲水性纤维素衍生物微粒，其分散液及其分散体; 并且提供由亲水性颗粒组成的诊断试剂，其具有优异的储存稳定性，并且不需要过量的组分如乳化剂或表面活性剂。本发明的纤维素衍生物微粒是由纤维素衍生物构成的纤维素衍生物微粒，其纤维素的一部分羟基被取代基取代，平均粒径为9〜1000nm，本发明的诊断试剂是通过将与试验对象物质差异相互作用的物质负载在上述纤维素衍生物微粒上而得到的诊断试剂。

43. 发明申请

US20130316892A1 METHOD FOR PRODUCING POLYMER PARTICLES, AND POLYMER PARTICLES 有权
标题翻译：生产聚合物颗粒的方法和聚合物颗粒
公开(公告)号：US20130316892A1
公开(公告)日：2013-11-28
申请号：US13994495
申请日：2011-12-14
申请人： Satoshi Nakamura , Tetsuo Fukuta , Kazuhiro Ikkyu , Yu Otani , Hiroshi Kawai
发明人： Satoshi Nakamura , Tetsuo Fukuta , Kazuhiro Ikkyu , Yu Otani , Hiroshi Kawai
IPC分类号： B01J20/281
CPC分类号： B01J20/281 , B01J20/267 , B01J20/285 , C08B1/003 , C08B15/10 , C08B37/0018 , C08B37/0021 , C08B37/003 , C08B37/0039 , C08J3/16 , C08J3/24 , C08J2301/02 , C08K5/0025 , C08L1/02 , C08L1/28 , C08L5/00 , C08L5/02 , C08L5/08 , C08L5/12 , Y02P20/542
摘要： Provided are polymer particles which can be used at a high flow rate when used as a filler for chromatography, that is, has excellent resistance flow rate appropriate for processing in large quantities, and also has a high binding capacity for target molecules such as proteins when an appropriate ligand is contained in the particles, and a method for producing the polymer particles; specifically, crosslinked polymer particles and a method for producing the crosslinked polymer particles, polysaccharide composite particles and a method for producing the polysaccharide composite particles, a filler for chromatography using the polymer particles, and an adsorbent for antibody purification. Disclosed are: A. a method for producing polysaccharide composite particles, the method including the following steps (1) to (3): (1) a step of preparing a polysaccharide solution, in which two or more kinds of polysaccharides are dissolved in an ionic liquid; (2) a step of preparing a droplet dispersion liquid of the polysaccharide solution, in which liquid droplets of the polysaccharide solution are dispersed in an organic solvent having low compatibility with the ionic liquid; and (3) a coagulation step in which a composite of the polysaccharides are coagulated to obtain the polysaccharide composite particles; and B. a method for producing a crosslinked polymer particle, the method including a step of allowing a polymer dissolved in an ionic liquid, to react with a crosslinking agent while the polymer is subjected to droplet dispersion in an organic solvent having low compatibility with the ionic liquid.
摘要翻译：提供当用作色谱填料时可以以高流速使用的聚合物颗粒，即具有适合于大量加工的优异的电阻流速，并且还具有对蛋白质等靶分子的高结合力粒子中含有适当的配体，以及聚合物粒子的制造方法。特别是交联聚合物颗粒和交联聚合物颗粒的制备方法，多糖复合颗粒和多糖复合颗粒的制备方法，使用该聚合物颗粒的色谱用填料和用于抗体纯化的吸附剂。本发明涉及A.一种多糖复合粒子的制造方法，其特征在于，包括以下工序（1）〜（3）：（1）制备多糖溶液的工序，其中将2种以上的多糖溶解于离子液体（2）将多糖溶液的液滴分散在与离子液体的相容性低的有机溶剂中的多糖溶液的液滴分散液的制备工序; 和（3）将多糖的复合体凝结而得到多糖复合粒子的凝固工序; 和B.一种制备交联聚合物颗粒的方法，该方法包括使溶解在离子液体中的聚合物与交联剂反应的步骤，同时聚合物在与离子液体。

44. 发明申请

US20130269890A1 TAMPON INCLUDING CROSSLINKED CELLULOSE FIBERS AND IMPROVED SYNTHESIS PROCESSES FOR PRODUCING SAME 审中-公开
公开(公告)号：US20130269890A1
公开(公告)日：2013-10-17
申请号：US13916195
申请日：2013-06-12
申请人： PLAYTEX PRODUCTS, LLC
发明人： Eugene P. Dougherty, JR. , Andrew Wilkes
IPC分类号： D21C9/00
CPC分类号： D21C9/005 , A61F13/2051 , A61F13/2082 , A61L15/28 , A61L15/42 , C08B15/10 , D01F2/08 , D06M11/70 , D06M13/123 , D06M13/192 , D06M13/432 , D06M2101/06 , C08L1/02
摘要： A tampon pledget includes crosslinked cellulose fibers having microstructures treated to provide improved absorbency and higher wet strength. The fibers are treated with a crosslinking agent to provide at least one of a molecular weight between crosslinks of from about 10 to 200 and a degree of crystallinity of from about 25% to 75%. The crosslinking agent includes citric acid in 1% by weight. The crosslinking agent may further include sodium hypophosphite in 1% by weight. In another embodiment, the crosslinking agent may be a difunctional agent including a glyoxal or a glyoxal-derived resin. In still another embodiment, the crosslinking agent is a multifunctional agent including a cyclic urea, glyoxal, polyol condensate. The crosslinking agent is added in an amount from about 0.001% to 20% by weight based on a total weight of cellulose fibers to be treated and, preferably, in an amount of about 5% by weight.

45. 发明申请

US20120328557A1 ADHESIVE CELL TISSUE GELS 审中-公开
标题翻译：粘合细胞组织胶
公开(公告)号：US20120328557A1
公开(公告)日：2012-12-27
申请号：US13167274
申请日：2011-06-23
申请人： Lynn L.H. Huang
发明人： Lynn L.H. Huang
IPC分类号： A61K38/19 , A61K38/30 , A61K35/12 , C08B37/00 , A61K38/18 , C08H1/00
CPC分类号： A61K47/34 , A61K38/18 , A61K38/1808 , A61K38/1816 , A61K38/1825 , A61K38/1833 , A61K38/1841 , A61K38/185 , A61K38/1858 , A61K38/1866 , A61K38/1875 , A61K38/193 , A61K38/30 , A61L27/222 , A61L27/24 , A61L27/3834 , A61L27/44 , A61L27/52 , A61L27/54 , A61L2300/414 , A61L2300/64 , C08B11/02 , C08B11/12 , C08B15/005 , C08B15/10 , C08B37/003 , C08B37/0039 , C08B37/0042 , C08B37/0063 , C08B37/0069 , C08B37/0072 , C08B37/0075 , C08B37/0084 , C08H1/00 , C08H1/06 , C08L77/04 , C12N5/0068 , C12N2537/10 , C08L89/06 , C08L5/08
摘要： Described herein is a cell tissue gel cross-linked with a cross-linking agent, and a quenching agent bound to a reactive group of the cross-linking agent.
摘要翻译：本文描述的是与交联剂交联的细胞组织凝胶，和与交联剂的反应性基团结合的猝灭剂。

46. 发明申请

US20110020954A1 CELLULOSE DERIVATIVE FINE PARTICLE, DISPERSION LIQUID THEREOF, DISPERSION BODY THEREOF AND DIAGNOSTIC REAGENT 有权
标题翻译：纤维素衍生微粒，其分散液，其分散体及诊断试剂
公开(公告)号：US20110020954A1
公开(公告)日：2011-01-27
申请号：US12935246
申请日：2009-03-30
申请人： Yoshiyuki Shiomi , Toshihiko Matsui , Masanori Doi
发明人： Yoshiyuki Shiomi , Toshihiko Matsui , Masanori Doi
IPC分类号： G01N33/544 , C08B1/00 , B32B5/16
CPC分类号： G01N33/548 , C08B1/006 , C08B1/08 , C08B5/14 , C08B11/02 , C08B11/04 , C08B11/08 , C08B11/10 , C08B11/12 , C08B11/145 , C08B11/155 , C08B11/20 , C08B15/005 , C08B15/04 , C08B15/10 , C08B16/00 , C08J3/16 , C08J2301/28 , C08L1/08 , C08L1/26 , C08L1/28 , C08L1/282 , C08L1/284 , C08L1/286 , C08L1/288 , G01N2400/26 , Y10T428/2982
摘要： An object of the present invention is to provide a hydrophilic cellulose derivative fine particle having a small particle size, a dispersion liquid thereof and a dispersion body thereof; and provide a diagnostic reagent composed of the hydrophilic particle, which is excellent in storage stability and does not require excess components, such as an emulsifier or surfactant. The cellulose derivative fine particle of the present invention is a cellulose derivative fine particle comprising a cellulose derivative with a part of hydroxyl groups of cellulose being substituted with a substituent, wherein the average particle diameter is from 9 to 1,000 nm; and the diagnostic reagent of the present invention is a diagnostic reagent obtained by loading a substance differentially interacting with a test object substance on the above-described cellulose derivative fine particle.
摘要翻译：本发明的目的是提供一种具有小粒径的亲水性纤维素衍生物微粒，其分散液及其分散体; 并且提供由亲水性颗粒组成的诊断试剂，其具有优异的储存稳定性，并且不需要过量的组分如乳化剂或表面活性剂。本发明的纤维素衍生物微粒是由纤维素衍生物构成的纤维素衍生物微粒，其纤维素的一部分羟基被取代基取代，平均粒径为9〜1000nm，本发明的诊断试剂是通过将与试验对象物质差异相互作用的物质负载在上述纤维素衍生物微粒上而得到的诊断试剂。

47. 发明授权

US07147446B2 Crosslinking agent application method and system 有权
标题翻译：交联剂应用方法和系统
公开(公告)号：US07147446B2
公开(公告)日：2006-12-12
申请号：US10336390
申请日：2003-01-02
申请人： Ray Crane
发明人： Ray Crane
IPC分类号： B29C43/28
CPC分类号： D21H23/32 , B29B15/122 , B29C43/46 , C08B15/10 , D21H23/48 , D21H25/12
摘要： Methods and systems for applying crosslinking agent to a sheet of cellulose fibers are described. The method and system apply crosslinking agent to one or both sides of the sheet and results in a sheet having a high loading of crosslinking agent that is uniformly distributed within the sheet.
摘要翻译：描述了将交联剂施用于纤维素纤维片材的方法和系统。该方法和系统将交联剂施加到片材的一侧或两侧，并产生具有均匀分布在片材内的交联剂的高负载量的片材。

48. 发明申请

US20050257905A1 Process and composition for preparing a lignocellulose-based product, and the product obtained by the process 审中-公开
标题翻译：用于制备基于木素纤维素的产品的方法和组合物，以及通过该方法获得的产物
公开(公告)号：US20050257905A1
公开(公告)日：2005-11-24
申请号：US11191964
申请日：2005-07-29
申请人： Oded Shoseyov
发明人： Oded Shoseyov
IPC分类号： A01H5/00 , C08B15/00 , C08B15/10 , C08B31/00 , C08B37/00 , C08B37/08 , C12N5/10 , C12N9/24 , C12N15/09 , C12P19/04 , C12S11/00 , D06M15/15 , D06M16/00 , D21C9/00 , D21H11/20 , D21H17/00 , D21H21/20 , D21C1/00
CPC分类号： C08B37/003 , C07K2319/00 , C08B15/00 , C08B15/10 , C08B31/00 , C08B37/00 , C12N9/2437 , C12Y302/01004 , D06M15/15 , D06M16/003 , D21C9/005 , D21H17/005
摘要： A process for the manufacture of a lignocellulose product, the process comprising the step of mixing in a reaction medium (i) a phenolic polymer being substituted with a phenolic hydroxy group; (ii) a lignocellulose containing material having immobilized to a cellulosic fraction thereof a fusion polypeptide, the fusion polypeptide including an enzyme being capable of catalyzing the oxidation of phenolic groups and a cellulose binding peptide; and (iii) an oxidizing agent. A composition of matter for use in the process and a lignocellulose product obtainable by the process are also disclosed.
摘要翻译：一种制备木质纤维素产品的方法，该方法包括在反应介质（i）被酚羟基取代的酚类聚合物上混合的步骤; （ii）含有固定在其纤维素级分上的融合多肽的含木素纤维素的材料，所述融合多肽包括能够催化酚基氧化的酶和纤维素结合肽; 和（iii）氧化剂。还公开了用于该方法的物质组合物和通过该方法可获得的木质纤维素产品。

49. 发明申请

US20050209355A1 [Novel Reactions and the Products of Such Reactions] 审中-公开
标题翻译： [新型反应和这种反应的产物]
公开(公告)号：US20050209355A1
公开(公告)日：2005-09-22
申请号：US10708732
申请日：2004-03-22
申请人： Lipa Roitman
发明人： Lipa Roitman
IPC分类号： C08B3/22 , C08B15/00 , C08B15/10 , C08F8/18 , C08F251/02 , C08F255/00 , C08F265/04 , C08F283/00 , C08F283/06 , C08F289/00 , C08F291/00 , C08G2/00
CPC分类号： C08B3/22 , C08B15/00 , C08B15/10 , C08F8/18 , C08F251/02 , C08F255/00 , C08F265/04 , C08F283/006 , C08F283/06 , C08F289/00 , C08F291/00
摘要： A process for the synthesis of novel compounds is described comprising reacting tetrachloroethylene with substances containing active methylene group in the presence of free radical initiators. Also, a process for grafting tetrachloroethylene is described comprising reacting these compounds with polymers containing active methylene group in the presence of free radical initiators. Furthermore, a method of conducting such reactions to high conversion is described, comprising conducting the reactions in the reflux condensate. The present invention provides a novel and high yield route for heretofore unobtainable materials.
摘要翻译：描述了合成新化合物的方法，其包括在自由基引发剂存在下使四氯乙烯与含有活性亚甲基的物质反应。另外，描述了接枝四氯乙烯的方法，其包括在自由基引发剂的存在下使这些化合物与含有活性亚甲基的聚合物反应。此外，描述了将这种反应进行高转化率的方法，包括在回流冷凝物中进行反应。本发明提供了迄今未知的材料的新颖且高产量的途径。

50. 发明申请

US20050143571A1 Method for forming individualized intrafiber crosslinked cellulosic fibers with improved brightness and color 审中-公开
标题翻译：用于形成具有改善的亮度和颜色的个体化纤维内纤维素纤维的方法
公开(公告)号：US20050143571A1
公开(公告)日：2005-06-30
申请号：US10748977
申请日：2003-12-30
申请人： Angel Stoyanov , Shahrokh Naieni , David Unrau
发明人： Angel Stoyanov , Shahrokh Naieni , David Unrau
IPC分类号： C08B3/16 , C08B15/10
CPC分类号： C08B15/10
摘要： A method for forming individualized intrafiber crosslinked cellulosic fibers with improved color and brightness properties.
摘要翻译：用于形成具有改进的颜色和亮度特性的个体化的纤维内交联纤维素纤维的方法。

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