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41. 发明授权

US09855098B2 Cavitary tissue ablation 有权
公开(公告)号：US09855098B2
公开(公告)日：2018-01-02
申请号：US15624230
申请日：2017-06-15
申请人： Innoblative Designs, Inc.
发明人： Robert F. Rioux
IPC分类号： A61B18/14 , A61B18/00
CPC分类号： A61B18/1492 , A61B2018/00083 , A61B2018/0016 , A61B2018/00238 , A61B2018/00255 , A61B2018/00267 , A61B2018/00333 , A61B2018/00452 , A61B2018/00505 , A61B2018/00529 , A61B2018/00541 , A61B2018/00547 , A61B2018/00559 , A61B2018/00577 , A61B2018/144 , A61B2018/1467 , A61B2018/1472 , A61B2218/002
摘要： The invention relates to a tissue ablation system including an ablation device having a deployable applicator head configured to be delivered to a tissue cavity and ablate marginal tissue surrounding the tissue cavity. The deployable applicator head is configured to be delivered to a tissue cavity while in a collapsed configuration and ablate marginal tissue surrounding the tissue cavity while in an expanded configuration.

42. 发明申请

US20170367760A1 ESOPHAGEAL ABLATION TECHNOLOGY 审中-公开
公开(公告)号：US20170367760A1
公开(公告)日：2017-12-28
申请号：US15486078
申请日：2017-04-12
申请人： Seth Crozier , Sohail Desai , Dan Kasprzyk , Bryce Alexander Igo
发明人： Seth Crozier , Sohail Desai , Dan Kasprzyk , Bryce Alexander Igo
IPC分类号： A61B18/18 , A61B18/00
CPC分类号： A61B18/1815 , A61B2018/00184 , A61B2018/00196 , A61B2018/00208 , A61B2018/0022 , A61B2018/00255 , A61B2018/00488 , A61B2018/00577 , A61B2018/00791 , A61B2018/00982 , A61B2018/1823 , A61B2018/1861 , A61B2018/1876
摘要： An esophageal ablation system including a positioner, an elongated, flexible shaft extending from the positioner, and a microwave emitter assembly disposed near the distal end of the shaft. The emitter assembly includes one or more microwave antennae and a balloon tor spacing the antennae relative to target tissue. The device may have an inner balloon for deploying the antenna. The systems, devices and methods disclosed are useful for treating Barrett's Esophagus, Esophageal Adenocarcinoma, and Squamous Cell Carcinoma.

43. 发明授权

US09808304B2 Cryogenic balloon device with electroporation treatment region 有权
公开(公告)号：US09808304B2
公开(公告)日：2017-11-07
申请号：US15347294
申请日：2016-11-09
申请人： Medtronic CryoCath LP
发明人： Jean-Pierre Lalonde
IPC分类号： A61B18/02 , A61B18/14 , A61B18/00
CPC分类号： A61B18/02 , A61B18/1492 , A61B2018/0022 , A61B2018/00255 , A61B2018/00351 , A61B2018/00357 , A61B2018/00613 , A61B2018/00642 , A61B2018/00702 , A61B2018/00714 , A61B2018/00791 , A61B2018/00863 , A61B2018/00898 , A61B2018/00994 , A61B2018/0212 , A61B2018/0262
摘要： An intravascular ablation device, including a flexible elongate body; an expandable element positioned on the elongate body; a radiofrequency or electroporation treatment segment located distally of the expandable element; a cryogenic coolant source in fluid communication with an interior of the expandable element; and a radiofrequency or electroporation energy source in communication with the radiofrequency or electroporation treatment segment.

44. 发明授权

US09750565B2 Electrosurgical balloons 有权
公开(公告)号：US09750565B2
公开(公告)日：2017-09-05
申请号：US13250104
申请日：2011-09-30
申请人： Eliot F. Bloom , Vaclav O. Podany , Chad M. Greenlaw , Brian M. Conley
发明人： Eliot F. Bloom , Vaclav O. Podany , Chad M. Greenlaw , Brian M. Conley
IPC分类号： A61B18/14 , A61B18/00 , A61B18/12
CPC分类号： A61B18/1492 , A61B2018/00255 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/126 , A61B2018/1472 , A61B2218/002
摘要： An electrosurgical balloon includes an inflatable balloon body formed of a non-conductive substrate material. One or more electrodes are disposed on an exterior surface of the balloon body. The electrodes can include a pair of bipolar electrodes, and the balloon body can have at least one fluid outlet hole configured to provide fluid to the pair of bipolar electrodes. A second inflatable balloon body can be disposed inside the first inflatable balloon body. The electrosurgical balloon can be incorporated into a catheter assembly, in which the electrosurgical balloon is a balloon electrode tip at a distal end of a catheter.

45. 发明授权

US09743973B2 Triple balloon catheter 有权
公开(公告)号：US09743973B2
公开(公告)日：2017-08-29
申请号：US14564907
申请日：2014-12-09
申请人： Medtronic CryoCath LP
发明人： Jean-Luc Pageard
IPC分类号： A61B18/02 , A61B18/00
CPC分类号： A61B18/02 , A61B2018/0022 , A61B2018/00255 , A61B2018/00261 , A61B2018/00375 , A61B2018/00577 , A61B2018/0212
摘要： The present invention advantageously provides a method and system for cryogenically ablating large areas of tissue within the left atrium. In an exemplary embodiment a cryotherapy device includes a catheter body, a proximal end and a distal end; a first lumen; a second lumen; and an ablation element expandable from a first diameter to a second diameter, the ablation element having a surface portion that conforms to the uneven surface topography of the cardiac tissue. The ablation element can include one or more deformable balloon and/or flexible elements. The surface of the balloon can further be shaped by regulation of pressure within the one or more balloons. In an exemplary method, a tissue ablation device is provided and tissue in the left atrium is ablated with the device, whereby the ablation is created by freezing tissue.

46. 发明授权

US09510888B2 Cryogenic balloon device with electroporation treatment region 有权
标题翻译：具有电穿孔处理区域的低温球囊装置
公开(公告)号：US09510888B2
公开(公告)日：2016-12-06
申请号：US14932565
申请日：2015-11-04
申请人： Medtronic CryoCath LP
发明人： Jean-Pierre Lalonde
IPC分类号： A61B18/02 , A61B18/14 , A61B18/00
CPC分类号： A61B18/02 , A61B18/1492 , A61B2018/0022 , A61B2018/00255 , A61B2018/00351 , A61B2018/00357 , A61B2018/00613 , A61B2018/00642 , A61B2018/00702 , A61B2018/00714 , A61B2018/00791 , A61B2018/00863 , A61B2018/00898 , A61B2018/00994 , A61B2018/0212 , A61B2018/0262
摘要： An intravascular ablation device, including a flexible elongate body; an expandable element positioned on the elongate body; a radiofrequency or electroporation treatment segment located distally of the expandable element; a cryogenic coolant source in fluid communication with an interior of the expandable element; and a radiofrequency or electroporation energy source in communication with the radiofrequency or electroporation treatment segment.
摘要翻译：一种血管内消融装置，包括柔性细长体; 定位在细长体上的可扩张元件; 位于可扩张元件的远侧的射频或电穿孔处理段; 与所述可膨胀元件的内部流体连通的低温冷却剂源; 以及与射频或电穿孔治疗部门通信的射频或电穿孔能量。

47. 发明授权

US09445859B2 Multifunctional ablation device 有权
标题翻译：多功能消融装置
公开(公告)号：US09445859B2
公开(公告)日：2016-09-20
申请号：US12696233
申请日：2010-01-29
申请人： Jean-Luc Pageard
发明人： Jean-Luc Pageard
IPC分类号： A61B18/02 , A61B18/00
CPC分类号： A61B18/02 , A61B18/1492 , A61B90/39 , A61B2018/00023 , A61B2018/00041 , A61B2018/00214 , A61B2018/0022 , A61B2018/00255 , A61B2018/00285 , A61B2018/00351 , A61B2018/00357 , A61B2018/00375 , A61B2018/00577 , A61B2018/00994 , A61B2018/0212 , A61B2018/0262
摘要： An intravascular catheter is provided, including a flexible elongate body; an expandable element positioned on the elongate body; a substantially linear thermal segment located proximally of the expandable element, the thermal segment defining a first flexibility, where the thermal segment is positioned between two portions of the catheter body each including a flexibility less than that of the thermal segment; a first fluid flow path in fluid communication with the expandable element; and a second fluid flow path in fluid communication with the thermal segment.
摘要翻译：提供血管内导管，包括柔性细长体; 定位在细长体上的可扩张元件; 位于所述可膨胀元件的近侧的基本上线性的热段，所述热段限定第一柔性，其中所述热段位于所述导管主体的两个部分之间，每个部分包括比所述热段的弹性小的柔性; 与可膨胀元件流体连通的第一流体流动路径; 以及与热段流体连通的第二流体流动路径。

48. 发明授权

US09439707B2 Spray nozzle design for a catheter 有权
标题翻译：导管喷嘴设计
公开(公告)号：US09439707B2
公开(公告)日：2016-09-13
申请号：US13071594
申请日：2011-03-25
申请人： Jean-Pierre Lalonde
发明人： Jean-Pierre Lalonde
IPC分类号： A61B18/02 , A61B18/00
CPC分类号： A61B18/02 , A61B2018/0022 , A61B2018/00255 , A61B2018/00351 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262
摘要： A catheter-based medical device including controlled refrigerant dispersion is disclosed. The device includes a fluid injection tube that carries refrigerant from a coolant supply to the distal portion of the device. A fluid dispersion unit is disposed on the distal end of the fluid tube to control the angle of distribution for refrigerant that is expelled from the fluid injection tube. Controlling the angle of distribution for the refrigerant facilitates dispersion of the fluid in a predetermined spray pattern. The disclosure further relates to cryoablation treatment systems incorporating such a catheter, and to cryoablation treatment methods for tissue treatment to address various conditions suitably treatable with cryoablation.
摘要翻译：公开了一种包括受控的制冷剂分散体的基于导管的医疗装置。该装置包括将制冷剂从冷却剂供应运送到装置的远端部分的流体注入管。流体分散单元设置在流体管的远端，以控制从流体注入管排出的制冷剂的分配角度。控制制冷剂的分配角度促进流体以预定的喷雾模式的分散。本公开还涉及包含这种导管的冷冻消融治疗系统，以及用于组织治疗的冷冻消融治疗方法，以解决适合于冷冻消融治疗的各种状况。

49. 发明授权

US09033965B2 Nested balloon cryotherapy 有权
标题翻译：嵌套气球冷冻治疗
公开(公告)号：US09033965B2
公开(公告)日：2015-05-19
申请号：US13019138
申请日：2011-02-01
申请人： Frank Ingle , Rebecca Tin , Robert F. Bencini , James Mazzone
发明人： Frank Ingle , Rebecca Tin , Robert F. Bencini , James Mazzone
IPC分类号： A61B18/02 , A61B18/00
CPC分类号： A61B18/02 , A61B2018/00255 , A61B2018/0212
摘要： A cryotherapy system includes a cryotherapy catheter having an inflatable balloon portion and a pressure regulator. The inflatable balloon portion includes an outer balloon and an inner balloon within the outer balloon. The inner balloon is configured to receive during a cryotherapy procedure a cryogenic agent for extracting heat from body tissue at a desired location. The inflatable balloon portion is at a distal end of the cryotherapy catheter. The pressure regulator is adapted to maintain a positive pressure between the inner balloon and the outer balloon during a cryotherapy procedure.
摘要翻译：冷冻治疗系统包括具有可充气球囊部分和压力调节器的冷冻治疗导管。可膨胀气囊部分包括外球囊和外球囊内的内球囊。内部气囊被配置为在冷冻治疗过程期间接收用于在期望位置从身体组织提取热量的低温剂。可膨胀气囊部分在冷冻治疗导管的远端。压力调节器适于在冷冻治疗过程期间在内部球囊和外部球囊之间保持正压力。

50. 发明授权

US08679105B2 Device and method for pulmonary vein isolation 有权
标题翻译：肺静脉隔离装置及方法
公开(公告)号：US08679105B2
公开(公告)日：2014-03-25
申请号：US12845312
申请日：2010-07-28
申请人： Dan Wittenberger , Ioana Alina Deac , Jean-Pierre Lalonde , Deborah A. De Roy
发明人： Dan Wittenberger , Ioana Alina Deac , Jean-Pierre Lalonde , Deborah A. De Roy
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B18/1492 , A61B2018/00255 , A61B2018/00285 , A61B2018/00375 , A61B2018/00577 , A61B2018/00994 , A61B2018/0212 , A61B2018/0262
摘要： An intravascular catheter is provided, including a flexible elongate body; an expandable element positioned on the elongate body; a substantially linear thermal segment located distally of the expandable element; a first fluid flow path in fluid communication with the expandable element; and a second fluid flow path in fluid communication with the substantially linear thermal segment.
摘要翻译：提供血管内导管，包括柔性细长体; 定位在细长体上的可扩张元件; 位于所述可扩张元件的远端的基本线性的热段; 与可膨胀元件流体连通的第一流体流动路径; 以及与所述基本上线性的热段流体连通的第二流体流动路径。

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