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    • 41. 发明授权
    • IC-processed polymer nano-liquid chromatoraphy system on-a-chip and method of making it
    • IC加工聚合物纳米液体色谱体系及其制备方法
    • US08323488B2
    • 2012-12-04
    • US13037192
    • 2011-02-28
    • Yu-Chong TaiQing HeJun XieChanglin PangTerry D. LeeDamien RodgerMatthieu Liger
    • Yu-Chong TaiQing HeJun XieChanglin PangTerry D. LeeDamien RodgerMatthieu Liger
    • B01D15/08B01D15/10B01D15/00
    • H05K3/284G01N30/6047G01N30/6095G01N2030/645G03F1/80G01N2030/625
    • Embodiments in accordance with the present invention relate to packed-column nano-liquid chromatography (nano-LC) systems integrated on-chip, and methods for producing and using same. The microfabricated chip includes a column, flits/filters, an injector, and a detector, fabricated in a process compatible with those conventionally utilized to form integrated circuits. The column can be packed with supports for various different stationary phases to allow performance of different forms of nano-LC, including but not limited to reversed-phase, normal-phase, adsorption, size-exclusion, affinity, and ion chromatography. A cross-channel injector injects a nanolitre/picolitre-volume sample plug at the column inlet. An electrochemical/conductivity sensor integrated at the column outlet measures separation signals. A self-aligned channel-strengthening technique increases pressure rating of the microfluidic system, allowing it to withstand the high pressure normally used in high performance liquid chromatography (HPLC). On-chip sample injection, separation, and detection of mixture of anions in water is successfully demonstrated using ion-exchange nano-LC.
    • 根据本发明的实施方案涉及集成在片上的填充柱纳米液相色谱(nano-LC)系统及其制造和使用方法。 微制造的芯片包括以常规用于形成集成电路的方法兼容的工艺制造的柱,过滤器,注射器和检测器。 该柱可以填充有用于各种不同固定相的载体,以允许不同形式的纳米LC的性能,包括但不限于反相,正相,吸附,尺寸排阻,亲和力和离子色谱。 交叉通道注射器在柱入口处注入纳升/皮升体积的样品塞。 集成在色谱柱出口处的电化学/电导率传感器测量分离信号。 自对准的通道加强技术提高了微流体系统的压力等级,使其能够承受通常用于高效液相色谱(HPLC)的高压。 使用离子交换纳米LC成功地证明了在水中阴离子的混合物的片上样品注入,分离和检测。
    • 46. 发明申请
    • Animal Mobile Entertainment Device
    • 动物移动娱乐设备
    • US20110277697A1
    • 2011-11-17
    • US13108261
    • 2011-05-16
    • John M. LipscombQing He
    • John M. LipscombQing He
    • A01K29/00A01K15/02
    • A01K15/025
    • An animal mobile that includes a mount from which a boom cantilevers carrying an animal plaything with the mobile defining a spring mass system having a plurality of springs and masses that cause the plaything to unpredictably move during animal interaction. The mount is configured for door mounting having a plurality of straps that wrap around respective door knobs. The mount includes a ball and socket boom coupling arrangement that defines a spring and enables adjustable boom attachment. A drive is operated to rotate the mobile in one direction storing potential energy in at least one mobile suspension line defining another spring with the energy being released rotating the mobile in an opposite direction when the drive is caused. System feedback from interaction of the plaything by an animal, e.g., cat, causes the plaything to dance and leap in a manner simulating live prey enticing further animal interaction.
    • 一种动物移动装置,包括一个悬挂装置,其中携带动物玩具的悬臂悬臂用移动装置限定弹簧质量系统,弹簧质量系统具有多个弹簧和质量,这些弹簧和质量在动物相互作用期间不可预测地移动。 该安装件被配置成用于门安装,其具有围绕相应的门把手缠绕的多个带子。 该安装座包括一个球窝连接装置,其限定了一个弹簧并使可调节的吊杆附件。 驱动器被操作以在一个方向上旋转移动件,该方向在限定另一个弹簧的至少一个移动悬挂线中存储势能,当发生驱动时,能量被释放,使得移动体沿相反方向旋转。 来自动物(例如猫)的玩物的相互作用的系统反馈导致玩物以模拟活的猎物诱导进一步的动物交互的方式跳舞和飞跃。
    • 47. 发明申请
    • Sifting Scoop
    • 筛选勺子
    • US20110266817A1
    • 2011-11-03
    • US13074897
    • 2011-03-29
    • John M. LipscombQing He
    • John M. LipscombQing He
    • A01K29/00A47F13/08
    • A01K1/0114
    • A sifting scoop for removing pet waste from litter in a litter box having a handle carrying a sifting cup having a mouth wider than a downstream pet waste retaining pocket formed by the cup. The handle overlies the sifting cup providing a waste shield. The handle includes a grip attached by a bridge to the cup that provides a hand guard and scoop hanger with the grip serving as a when the scoop is stood uprightly on a pedestal formed by a cup endwall. The cup has a first sifting portion formed in a litter-engaging surface on the side opposite the handle with the sifting portion formed by a plurality of elongate slots that are wavy or S-shaped extending longitudinally in the direction of scooping. The cup has a second sifting portion having slots in the end wall inline with litter being scooped.
    • 一种用于在垃圾箱中从垃圾箱中排出宠物废物的筛选勺子,该垃圾箱具有手柄,该把手带有比由杯形成的下游宠物废物保留袋口宽的筛子。 手柄覆盖提供垃圾屏蔽的筛分杯。 手柄包括一个通过桥连接到杯子上的把手,该把手提供一把手把手和勺子挂钩,把手用作当勺子直立地放置在由杯形端壁形成的基座上时。 杯子具有形成在与把手相对的一侧上的垫料接合表面中的第一筛分部分,其中筛分部分由多个细长的狭槽形成,该细长的槽沿着舀取的方向纵向延伸成波浪形或S形。 杯子具有第二筛分部分,该第二筛分部分在末端壁上具有与被舀取的枯枝落叶一致的槽。