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41. 发明授权

US09089652B2 Drive mechanism for a medication delivery device and medication delivery device 有权
标题翻译：药物输送装置和药物输送装置的驱动机构
公开(公告)号：US09089652B2
公开(公告)日：2015-07-28
申请号：US13133884
申请日：2009-12-09
申请人： Philippe Nzike , Steffen Raab , Ulrich Brüggemann , Uwe Dasbach , Uwe Boeser
发明人： Philippe Nzike , Steffen Raab , Ulrich Brüggemann , Uwe Dasbach , Uwe Boeser
IPC分类号： A61M5/00 , A61M5/315 , A61M5/24
CPC分类号： A61M5/31551 , A61M5/24 , A61M5/3148 , A61M5/31511 , A61M5/31515 , A61M5/31528 , A61M5/31535 , A61M5/31536 , A61M5/31541 , A61M5/31543 , A61M5/31555 , A61M5/31556 , A61M5/31558 , A61M5/3156 , A61M5/31561 , A61M5/3157 , A61M5/31575 , A61M5/3158 , A61M5/31581 , A61M5/31585 , A61M5/31593 , A61M2005/2407 , A61M2005/3152 , A61M2205/581 , A61M2205/582 , F16H25/12 , F16H25/20 , F16H31/001 , Y10T74/18568 , Y10T74/18696
摘要： A drive mechanism for a medication delivery device (1) is proposed, the drive mechanism comprising a housing (13, 17, 40) having a proximal end and a distal end, a rotation member (21) which is adapted to be rotated in a first direction with respect to the housing during setting of a dose of a medication and to be rotated in a second direction with respect to the housing during delivery of the dose, the second direction being opposite to the first direction, a piston rod (12) which is adapted to be displaced in a distal direction with respect to the housing for delivering the dose, a drive member (20) which follows rotational movement of the rotation member in the second direction during delivery of the dose, and a stop member (26) which prevents rotational movement of the drive member with respect to the housing in the first direction during setting of the dose, wherein the rotational movement of the drive member in the second direction is converted into movement of the piston rod in the distal direction with respect to the housing. Furthermore, a medication delivery device is provided for.
摘要翻译：提出了一种用于药物输送装置（1）的驱动机构，所述驱动机构包括具有近端和远端的壳体（13,17,40），旋转构件（21），其适于在第一方向相对于壳体在设置药物剂量期间相对于壳体在第二方向上相对于壳体在剂量递送期间旋转，第二方向与第一方向相反，活塞杆（12）其适于相对于用于输送剂量的壳体在远端方向上移位;驱动构件（20），其在所述剂量递送期间沿所述旋转构件沿所述第二方向旋转运动;以及止动构件（26）），其在剂量设定期间防止驱动构件相对于壳体在第一方向上的旋转运动，其中驱动构件在第二方向上的旋转运动转换为活塞杆的运动相对于壳体的远端方向。此外，提供了一种药物输送装置。

42. 发明授权

US08968258B2 Resettable drive mechanism for a medication delivery device and medication delivery device 有权
标题翻译：用于药物输送装置和药物输送装置的可重置驱动机构
公开(公告)号：US08968258B2
公开(公告)日：2015-03-03
申请号：US13133933
申请日：2009-12-09
申请人： Philippe Nzike , Steffen Raab , Ulrich Brüggemann , Uwe Dasbach , Uwe Boeser
发明人： Philippe Nzike , Steffen Raab , Ulrich Brüggemann , Uwe Dasbach , Uwe Boeser
IPC分类号： A61M5/315 , A61M5/24
CPC分类号： A61M5/31543 , A61M5/24 , A61M5/31511 , A61M5/31515 , A61M5/31535 , A61M5/31536 , A61M5/31541 , A61M5/31555 , A61M5/31556 , A61M5/31558 , A61M5/3156 , A61M5/31561 , A61M5/3157 , A61M5/31575 , A61M5/3158 , A61M5/31581 , A61M5/31585 , A61M5/31593 , A61M2005/2407 , A61M2005/3152 , A61M2205/581 , A61M2205/582
摘要： A resettable drive mechanism for a medication delivery device comprising a housing and a drive member rotatable in a second direction for delivering a dose. A piston rod driven distally when a drive member rotates in the second direction. A stop member prevents rotation of the drive member in a first direction opposite the second direction, when the stop member engages the drive member. A clutch member is movable between a delivery and reset position. When the clutch member is in the delivery position, the stop member and the drive member engage and the drive member is prevented from rotating in the first direction. When the clutch member is in the reset position, the drive member and the stop member disengage. The drive member is rotatable in the first direction.
摘要翻译：一种用于药物输送装置的可重置驱动机构，包括壳体和可沿第二方向旋转的用于递送剂量的驱动构件。当驱动构件沿第二方向旋转时，活塞杆向远侧驱动。当止动构件接合驱动构件时，止动构件防止驱动构件沿与第二方向相反的第一方向旋转。离合器构件可在输送和复位位置之间移动。当离合器构件处于排出位置时，停止构件和驱动构件接合，并且防止驱动构件沿第一方向旋转。当离合器构件处于复位位置时，驱动构件和止动构件脱开。驱动构件可沿第一方向旋转。

43. 发明授权

US08968257B2 Coded cartridge holder system for a fluid delivery device 有权
标题翻译：用于流体输送装置的编码盒式支架系统
公开(公告)号：US08968257B2
公开(公告)日：2015-03-03
申请号：US13642554
申请日：2011-04-21
申请人： Uwe Dasbach , Steffen Raab , Michael Harms , Udo Stauder , Volker Korger
发明人： Uwe Dasbach , Steffen Raab , Michael Harms , Udo Stauder , Volker Korger
IPC分类号： A61M5/315 , A61M5/50 , A61M5/24
CPC分类号： A61M5/5086 , A61M5/24 , A61M5/31551 , A61M2005/2407 , A61M2005/2433 , A61M2005/2488 , A61M2005/2492 , A61M2205/6045
摘要： A coded cartridge holder system is disclosed for use with a cartridge assembly (20) containing a fluid and a delivery device (10), where the system has keyed connectors (5, 5′, 6, 6′) to prevent accidental attachment of the wrong fluid delivery device (10). The system comprises a coupling (1) attachable to the dose setting portion (12) of the device (10) and keyed to the proximal end of the cartridge holder (14). The cartridge holder (14) may also contain medical coding (27, 28) to correspond to matching coding (27′, 28′) on the distal end of a cartridge assembly (20).
摘要翻译：公开了一种与包含流体和输送装置（10）的盒组件（20）一起使用的编码盒式存储器系统，其中系统具有键控连接器（5,5'，6,6'），以防止意外地附接错误的流体输送装置（10）。该系统包括可连接到装置（10）的剂量设定部分（12）并且键合到药筒保持器（14）的近端的联接器（1）。药筒保持器（14）还可以包含医疗编码（27,28），以对应于药筒组件（20）的远端上的匹配编码（27'，28'）。

44. 发明申请

US20130211326A1 Coded Cartridge Holder System for a Fluid Delivery Device 有权
标题翻译：用于流体输送装置的编码筒支架系统
公开(公告)号：US20130211326A1
公开(公告)日：2013-08-15
申请号：US13642554
申请日：2011-04-21
申请人： Uwe Dasbach , Steffen Raab , Michael Harms , Udo Stauder , Volker Korger
发明人： Uwe Dasbach , Steffen Raab , Michael Harms , Udo Stauder , Volker Korger
IPC分类号： A61M5/50
CPC分类号： A61M5/5086 , A61M5/24 , A61M5/31551 , A61M2005/2407 , A61M2005/2433 , A61M2005/2488 , A61M2005/2492 , A61M2205/6045
摘要： A coded cartridge holder system is disclosed for use with a cartridge assembly (20) containing a fluid and a delivery device (10), where the system has keyed connectors (5, 5′, 6, 6′) to prevent accidental attachment of the wrong fluid delivery device (10). The system comprises a coupling (1) attachable to the dose setting portion (12) of the device (10) and keyed to the proximal end of the cartridge holder (14). The cartridge holder (14) may also contain medical coding (27, 28) to correspond to matching coding (27′, 28′) on the distal end of a cartridge assembly (20).
摘要翻译：公开了一种与包含流体和输送装置（10）的盒组件（20）一起使用的编码盒式存储器系统，其中系统具有键控连接器（5,5'，6,6'），以防止意外地附接错误的流体输送装置（10）。该系统包括可连接到装置（10）的剂量设定部分（12）并且键合到药筒保持器（14）的近端的联接器（1）。药筒保持器（14）还可以包含医疗编码（27,28），以对应于药筒组件（20）的远端上的匹配编码（27'，28'）。

45. 发明申请

US20120071834A1 METHOD OF MANUFACTURING A DRUG DELIVERY DEVICE BODY 审中-公开
标题翻译：制造药物递送装置体的方法
公开(公告)号：US20120071834A1
公开(公告)日：2012-03-22
申请号：US13258164
申请日：2010-03-31
申请人： Michael Harms , Steffen Raab , Uwe Dasbach , Udo Stauder
发明人： Michael Harms , Steffen Raab , Uwe Dasbach , Udo Stauder
IPC分类号： A61M5/31 , A61M5/178 , B32B37/18 , B31B1/62 , B32B37/12
CPC分类号： B32B37/1292 , A61M5/3129 , A61M2205/583 , A61M2205/60 , A61M2207/00 , Y10T156/10
摘要： The invention relates to a method for manufacturing a drug delivery device body comprising the following steps: At first a first part of the drug delivery device body wherein the surface of the first part of the drug delivery device body consists of at least one selected area and at least one non selected area is provided. The selected area of the drug delivery device body is a part of the contact area of the first part and a second part of the drug delivery device body to be fixed to the first part of the drug delivery device body. Subsequently a layer of an adhesive is deposited on the surface of the first part; means for deposition of the adhesive only in the selected area are provided. The first part with the layer of adhesive and the second part are joined so that the layer of the adhesive is only arranged in the contact area of the first and the second part of the drug delivery device body.
摘要翻译：本发明涉及一种用于制造药物递送装置主体的方法，包括以下步骤：首先，药物递送装置主体的第一部分，其中药物递送装置主体的第一部分的表面由至少一个选定区域组成，提供至少一个未选择的区域。药物输送装置主体的选定区域是药物输送装置主体的第一部分和第二部分的接触区域的一部分，其被固定到药物输送装置主体的第一部分。随后，在第一部分的表面上沉积一层粘合剂; 提供了仅在选定区域中沉积粘合剂的装置。具有粘合剂层的第一部分和第二部分被接合，使得粘合剂层仅布置在药物递送装置主体的第一部分和第二部分的接触区域中。

46. 发明授权

US10543321B2 Pen cap 有权
公开(公告)号：US10543321B2
公开(公告)日：2020-01-28
申请号：US13258168
申请日：2010-03-31
申请人： Michael Harms , Steffen Raab
发明人： Michael Harms , Steffen Raab
IPC分类号： A61M5/32 , A61M5/31
摘要： The present invention refers to a pen cap, being capable of covering a distal end of a drug delivery device comprising at least one protruding element located inside the pen cap which prevents that the rim of an outer needle cap, while being a protective casing for the needle at the distal end of the drug delivery device, can get stuck within a part of the pen cap if the user puts the pen cap on the drug delivery device. The inner diameter of the pen cap is reduced by means of the at least one protruding element, such that the inner diameter of the pen cap is smaller than the largest outer diameter of the outer needle cap. Furthermore, the invention relates to a drug delivery device comprising a pen cap with the described protruding elements.

47. 发明授权

US09555194B2 Drug delivery device 有权
标题翻译：给药装置
公开(公告)号：US09555194B2
公开(公告)日：2017-01-31
申请号：US13258158
申请日：2010-03-31
申请人： Michael Harms , Volker Korger , Uwe Dasbach , Steffen Raab
发明人： Michael Harms , Volker Korger , Uwe Dasbach , Steffen Raab
IPC分类号： A61M5/315 , A61M5/178 , A61M5/31
CPC分类号： A61M5/31525 , A61M5/178 , A61M5/315 , A61M5/31543 , A61M2005/3115
摘要： A mechanism in the body is used to drive a piston rod and comprises means for guiding the movement of the piston rod relatively to the body while delivering the drug. Further means are provided for releasing the piston rod from the means for guiding the movement, thus enabling a reset of the piston rod to a start position, especially after the receptacle has been emptied and is to be refilled. The device is constructed in such a manner that a reset of the piston rod is facilitated by a stop element inhibiting a reversal of the movement of the piston rod when being reset.
摘要翻译：身体中的机构用于驱动活塞杆，并且包括用于在输送药物的同时引导活塞杆相对于身体的运动的装置。提供了用于将活塞杆从用于引导运动的装置释放的另外的装置，从而使活塞杆能够复位到起始位置，特别是在容器被排空并被重新填充之后。该装置的结构是这样一种方式：活塞杆的复位由止动件有助于在复位时阻止活塞杆运动反转。

48. 发明授权

US09533447B2 Method for manufacturing a composite work piece for a drug delivery device and composite work piece for a drug delivery device 有权
标题翻译：用于药物输送装置的复合工件的制造方法和药物输送装置的复合工件
公开(公告)号：US09533447B2
公开(公告)日：2017-01-03
申请号：US13203599
申请日：2010-03-31
申请人： Michael Harms , Steffen Raab , Uwe Dasbach
发明人： Michael Harms , Steffen Raab , Uwe Dasbach
IPC分类号： B29C65/14 , B23K26/22 , B29C65/56 , B29C65/64 , B29C65/66 , B29C65/78 , B29C65/00 , B29C65/16 , B29K705/00 , B29L31/00
CPC分类号： B29C65/14 , B23K26/22 , B23K26/282 , B23K2101/06 , B29C65/1435 , B29C65/1441 , B29C65/1635 , B29C65/1654 , B29C65/1677 , B29C65/565 , B29C65/64 , B29C65/66 , B29C65/7814 , B29C65/7855 , B29C66/1122 , B29C66/1142 , B29C66/124 , B29C66/21 , B29C66/5344 , B29C66/547 , B29C66/612 , B29C66/73115 , B29C66/73116 , B29C66/73921 , B29C66/742 , B29C66/8262 , B29K2705/00 , B29L2031/7544
摘要： Method for manufacturing a composite work piece for a drug delivery device, comprising the steps: Providing a first work piece part 1 and a second work piece part 2, arranging both work piece parts 1, 2 with respect to each other in such a way that both work piece parts 1, 2 are in mechanical contact with one another in a contact area 3, irradiating a surface of the first work piece part 1 with electromagnetic radiation, thereby softening the first work piece part 1 and/or the second work piece part 2 in a region adjacent to the contact area 3, and joining the first work piece part 1 to the second work piece part 2 in the contact area 3 for the composite work piece. Furthermore, a composite work piece for a drug delivery device is provided.
摘要翻译：一种药物输送装置用复合制品的制造方法，其特征在于，具备：第一工件部件1和第二工件部件2，使工件零件1,2彼此相对配置，两个工件部件1,2在接触区域3中彼此机械接触，用电磁辐射照射第一工件部件1的表面，从而软化第一工件部件1和/或第二工件部件 2在与接触区域3相邻的区域中，并且将第一工件部件1连接到用于复合工件的接触区域3中的第二工件部件2。此外，提供了用于药物输送装置的复合工件。

49. 发明授权

US09526840B2 Drug delivery device 有权
标题翻译：药物输送装置
公开(公告)号：US09526840B2
公开(公告)日：2016-12-27
申请号：US13258160
申请日：2010-03-31
申请人： Michael Harms , Volker Korger , Uwe Dasbach , Steffen Raab
发明人： Michael Harms , Volker Korger , Uwe Dasbach , Steffen Raab
IPC分类号： A61M5/315
CPC分类号： A61M5/31543 , A61M5/24 , A61M5/31525 , A61M5/31528 , A61M2005/2481
摘要： A mechanism in the body is used to drive a piston rod and comprises means for guiding the movement of the piston rod relatively to the body while delivering the drug. Further means are provided for releasing the piston rod from the means for guiding the movement, thus enabling a reset of the piston rod to a start position, especially after the receptacle has been emptied and is to be refilled. The device is constructed in such a manner that a reset of the piston rod is facilitated.
摘要翻译：身体中的机构用于驱动活塞杆，并且包括用于在输送药物的同时引导活塞杆相对于身体的运动的装置。提供了用于将活塞杆从用于引导运动的装置释放的另外的装置，从而使活塞杆能够复位到起始位置，特别是在容器被排空并被重新填充之后。该装置构造成使得活塞杆的复位变得容易。

50. 发明授权

US09498576B2 Drive mechanism for a drug delivery device 有权
标题翻译：药物输送装置的驱动机构
公开(公告)号：US09498576B2
公开(公告)日：2016-11-22
申请号：US13702808
申请日：2011-06-09
申请人： Steffen Raab , Christopher James Smith , Mark Philip Horlock , Stephen David Butler
发明人： Steffen Raab , Christopher James Smith , Mark Philip Horlock , Stephen David Butler
IPC分类号： A61M5/315 , A61M5/24
CPC分类号： A61M5/31543 , A61M5/24 , A61M5/3155 , A61M5/31551 , A61M5/31553 , A61M5/31555 , A61M5/3158 , A61M5/31583 , A61M5/31585
摘要： A drive mechanism for a drug delivery device which can be switched between a normal operation state and a reset state comprises of a housing having a proximal end and a distal end, a rotation member which is adapted to rotate in a first direction and in a second direction with respect to the housing, a drive member, wherein in the normal operation state the rotation member is coupled with the drive member so that the drive member follows rotational movement of the rotation member in the second direction, a piston rod, wherein in the normal operation state the piston rod is displaced in a distal direction with respect to the housing when the drive member rotates in the second direction with respect to the housing, a stop member, wherein in the normal operation state the stop member is coupled with the drive member so that the stop member prevents rotational movement of the drive member with respect to the housing in the first direction, and a separation member for switching the operation state, the separation member being adapted to move the stop member and the drive member in the distal direction with respect to the housing when the normal operation state is switched to the reset state, thereby decoupling the stop member and the drive member and decoupling the drive member and the rotation member.
摘要翻译：用于可在正常操作状态和复位状态之间切换的药物输送装置的驱动机构包括具有近端和远端的壳体，适于沿第一方向旋转的旋转构件方向相对于壳体，驱动构件，其中在正常操作状态下，旋转构件与驱动构件联接，使得驱动构件沿第二方向旋转构件的旋转运动，活塞杆，其中在当驱动构件相对于壳体沿第二方向旋转时，活塞杆相对于壳体在远端方向上移位，其中在正常操作状态下，止动构件与驱动器联接使得止动构件防止驱动构件相对于壳体沿第一方向的旋转运动，以及用于切换操作的分离构件 n状态，当正常操作状态切换到复位状态时，分离构件适于在远端方向上相对于壳体移动止动构件和驱动构件，从而使止动构件和驱动构件分离，驱动构件和旋转构件。

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