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    • 48. 发明授权
    • Obtaining information from time variation of sensing results
    • 从感测结果的时间变化中获取信息
    • US07817254B2
    • 2010-10-19
    • US12022485
    • 2008-01-30
    • Alex HegyiMichael BasslerPeter KieselNoble M. Johnson
    • Alex HegyiMichael BasslerPeter KieselNoble M. Johnson
    • G01P3/36
    • G01N21/05B01L3/5027B01L3/502761G01N15/12G01N15/1429G01N15/1434G01N15/1463G01N15/1475G01N15/1484G01N2015/1037G01N2015/1075G01N2015/1093G01N2015/1254G01N2015/1472G01N2015/1486G01N2021/0346
    • Sensing results from moving objects, e.g. from photosensing emanating light or from impedance-based sensing, can indicate sensed time-varying waveforms with information about objects. For example, a sensed time-varying waveform can be compared with another waveform, such as a reference waveform produced by objects of a certain type, to obtain comparison results indicating motion-independent information about the object; time-scaling can adjust for displacement rate such as speed. Also, a modulation periodicity value can be obtained from a sensed time-varying waveform and used in obtaining information about an object; for example, a periodic modulation frequency can be used with a given time's chirp frequency to obtain phase information about an object's position. Or, where periodic modulation frequency indicates displacement rate, time scaling during comparison can use a scaling factor based on the frequency. Objects can move fluidically as in flow cytometry or through scanning movement, as in document scanning.
    • 感测来自移动物体的结果,例如 从光敏发射光或基于阻抗的感测可以用关于对象的信息来指示感测的时变波形。 例如,可以将感测到的时变波形与诸如由某种类型的对象产生的参考波形的另一波形进行比较,以获得指示关于对象的运动无关信息的比较结果; 时间缩放可以调整速度等位移速率。 此外,可以从感测到的时变波形获得调制周期值,并用于获得关于对象的信息; 例如,可以使用周期调制频率与给定时间的啁啾频率来获得关于对象的位置的相位信息。 或者,在周期性调制频率表示位移速率的情况下,比较期间的时间缩放可以使用基于频率的缩放因子。 物体可以像流式细胞仪一样流动,也可以通过扫描运动进行流动,如文档扫描。
    • 49. 发明申请
    • Transmitting/Reflecting Emanating Light With Time Variation
    • 发射/反射发光随时间变化
    • US20100201988A1
    • 2010-08-12
    • US12762702
    • 2010-04-19
    • Peter KieselMarkus BeckNoble M. JohnsonMichael Bassler
    • Peter KieselMarkus BeckNoble M. JohnsonMichael Bassler
    • G01N21/25G01N21/85
    • G01N21/05G01N21/255G01N21/645G01N2021/0346
    • A filter arrangement can transmit and/or reflect light emanating from a moving object so that the emanating light has time variation, and the time variation can include information about the object, such as its type. For example, emanating light from segments of a path can be transmitted/reflected through positions of a filter assembly, and the transmission functions of the positions can be sufficiently different that time variation occurs in the emanating light between segments. Or emanating light from a segment can be transmitted/reflected through a filter component in which simpler transmission functions are superimposed, so that time variation occurs in the emanating light in accordance with superposition of two simpler non-uniform transmission functions. Many filter arrangements could be used, e.g. the filter component could include the filter assembly, which can have one of the simpler non-uniform transmission functions. Time-varying waveforms from sensing results can be compared to obtain spectral differences. The filter arrangement, in a practical commercial embodiment, can be manufactured to be disposable, and used in a point-of-care device for use practically anywhere, at low cost, and can also be implemented in an in-line monitoring system.
    • 滤波器装置可以发射和/或反射从移动物体发出的光,使得发射光具有时间变化,并且时间变化可以包括关于物体的信息,例如其类型。 例如,可以通过路径的区段发出光,并通过过滤器组件的位置进行透射/反射,并且位置的透射函数可以充分地不同,从而在区间之间的发光中发生时间变化。 或者发射来自光束的光可以通过其中叠加更简单的透射函数的滤光器部件被透射/反射,使得根据两个更简单的不均匀透射函数的叠加在发射光中发生时间变化。 可以使用许多过滤装置,例如 过滤器组件可以包括过滤器组件,其可以具有更简单的不均匀传输功能之一。 可以比较感测结果中的时变波形,以获得光谱差异。 在实用的商业实施例中,过滤器装置可以制造为一次性的,并且用于实际上在任何地方,以低成本使用的点护理装置,并且也可以在在线监测系统中实现。
    • 50. 发明申请
    • Obtaining Sensing Results Indicating Time Variation
    • 获取传感结果指示时间变化
    • US20100155577A1
    • 2010-06-24
    • US12337737
    • 2008-12-18
    • Peter KieselJoerg MartiniMichael BasslerMarkus BeckNoble M. Johnson
    • Peter KieselJoerg MartiniMichael BasslerMarkus BeckNoble M. Johnson
    • G01J1/42G06F15/00G01N21/00
    • G01N15/1429G01N15/1056G01N15/12G01N15/1459G01N2015/1006G01N2015/1037G01N2015/1075
    • In response to objects having relative motion within an encoding/sensing region relative to an encoder/sensor that, e.g., photosenses emanating light or performs impedance-based sensing, sensing results can indicate sensed time-varying waveforms with information about the objects, about their relative motion, about excitation characteristics, about environmental characteristics, and so forth. An encoder/sensor can include, for example, a non-periodic arrangement of sensing elements; a longitudinal sequence of sensing elements with a combined sensing pattern that approximates a superposition or scaled superposition of simpler sensing patterns; and/or IC-implemented sensing elements that include photosensing arrays on ICs and readout/combine circuitry that reads out photosensed quantities from cells in groups in accordance with cell-group sensing patterns and combines the readout photosensed quantities to obtain the sensing results. Objects can move fluidically as in flow cytometry, through scanning movement as in document scanning, or in other ways.
    • 响应于在编码/感测区域内相对于编码器/传感器具有相对运动的物体,例如,发出光的光照或执行基于阻抗的感测,感测结果可以指示感测到的具有关于物体的信息的时变波形,关于它们 相对运动,关于激发特性,关于环境特性等。 编码器/传感器可以包括例如感测元件的非周期性布置; 具有组合感测图案的感测元件的纵向序列,其近似于更简单的感测图案的叠加或缩放叠加; 和/或IC实现的感测元件,其包括IC上的光敏阵列和读出/组合电路,其根据单元组感测图案从组中的单元读出光照量,并组合读出的光照量以获得感测结果。 物体可以像流式细胞仪一样流动地进行扫描运动,如文档扫描或其他方式。