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41. 发明授权

US09029536B2 Fused heterocyclic compounds 有权
公开(公告)号：US09029536B2
公开(公告)日：2015-05-12
申请号：US13814073
申请日：2011-08-03
申请人： Joseph Raker , Takahiko Taniguchi , Masato Yoshikawa , Tomoaki Hasui , Jun Kunitomo
发明人： Joseph Raker , Takahiko Taniguchi , Masato Yoshikawa , Tomoaki Hasui , Jun Kunitomo
IPC分类号： C07D471/04 , C07D471/14 , C07D519/00
CPC分类号： C07D471/04 , C07D471/14 , C07D519/00
摘要： The present invention provides a compound which has the effect of PDE 10A inhibition, and which is useful as a medicament for preventing or treating schizophrenia or so on. A compound represented by the formula (1′): wherein, Ring A′ represents an optionally substituted pyridine ring, an optionally substituted pyridazine ring, a pyrimidine ring, or 10 a pyrazine ring, R1′ represents (1) wherein, R1a′ represents an optionally substituted phenyl group, or an optionally substituted 5- to 10-membered heterocyclic group, Ring B2 represents a bond, —S—, -0-, —CO—, an optionally substituted methylene group, or —NRa′— (Ra′ represents a hydrogen atom, or an optionally substituted C1-6 alkyl group), and Ring B1′ represents an optionally further substituted 6- to 10-membered aromatic hydrocarbon ring, or an optionally further substituted 5- to 10-membered aromatic heterocyclic ring, or alternatively, L′ and R1a′ may be taken together to form an optionally substituted bicyclic or tricyclic fused heterocyclic group, or (2), wherein, R1b′ represents an optionally substituted phenyl group, or an optionally substituted 5- to 10-membered heterocyclic group, Ring B2′ represents an optionally substituted benzene ring, an optionally substituted pyridine ring, an optionally substituted pyrimidine ring, an optionally substituted pyrazine ring, or an optionally substituted pyridazine ring, Ring D′ represents an optionally further substituted 5- or 6-membered ring, R2′ represents a hydrogen atom, or a substituent, X′ represents ═N— or ═CRb′—(Rb′ represents a hydrogen atom, or a substituent), - - - - - represents that Rb′ and R2′ may form, taken together with the carbon atom and the nitrogen atom to which they are each adjacent, an optionally substituted 5- to 7-membered ring when.X′ is ═CRb′, or a salt thereof.

42. 发明授权

US08563575B2 Fused heterocyclic compounds 有权
公开(公告)号：US08563575B2
公开(公告)日：2013-10-22
申请号：US13166212
申请日：2011-06-22
申请人： Takahiko Taniguchi , Masato Yoshikawa , Kasei Miura , Tomoaki Hasui , Eiji Honda , Keisuke Imamura , Makoto Kamata , Haruhi Kamisaki
发明人： Takahiko Taniguchi , Masato Yoshikawa , Kasei Miura , Tomoaki Hasui , Eiji Honda , Keisuke Imamura , Makoto Kamata , Haruhi Kamisaki
IPC分类号： A01N43/42 , A61K31/44
CPC分类号： A61K31/4353 , A61K31/4355 , A61K31/437 , A61K31/4427 , A61K31/4439 , A61K31/444 , A61K31/4985 , A61K31/5025 , A61K31/519 , A61K31/52 , A61K31/522 , A61K31/551 , C07D401/14 , C07D403/04 , C07D403/14 , C07D413/14 , C07D471/04 , C07D471/14 , C07D473/00 , C07D473/28 , C07D487/04 , C07D495/04 , C07D498/04 , C07D498/08 , C07D519/00 , C07F7/10
摘要： The present invention provides a compound which has the effect of PDE inhibition, and which is useful as an agent for preventing or treating schizophrenia. The compound is represented by the formula (I): wherein the symbols are defined in the specification.

43. 发明申请

US20120277204A1 PYRIDAZINONE COMPOUNDS 有权
公开(公告)号：US20120277204A1
公开(公告)日：2012-11-01
申请号：US13543207
申请日：2012-07-06
申请人： Takahiko TANIGUCHI , Akira Kawada , Mitsuyo Kondo , John F. Quinn , Jun Kunitomo , Masato Yoshikawa , Makoto Fushimi
发明人： Takahiko TANIGUCHI , Akira Kawada , Mitsuyo Kondo , John F. Quinn , Jun Kunitomo , Masato Yoshikawa , Makoto Fushimi
IPC分类号： A61K31/501 , C07D413/14 , A61K31/5377 , C07D401/14 , A61P25/18 , C07D409/04 , C07D405/14 , C07D409/14 , C07D403/14 , C07D403/04 , C07D413/04
CPC分类号： C07D403/04 , A61K9/2059 , C07D401/14 , C07D403/14 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/14 , C07D413/04 , C07D413/14
摘要： The present invention provides a compound which has the effect of PDE inhibition, and which is useful as a medicament for preventing or treating schizophrenia or so on. A compound of formula (I0), wherein R1 represents a substituent; R2 represents a hydrogen atom, or a substituent; R3 represents a hydrogen atom, or a substituent; Ring A represents an aromatic ring which can be substituted, and Ring B represents a 5-membered heteroaromatic ring which can be substituted, or a salt thereof.

44. 发明申请

US20120028951A1 PYRIDAZINONE COMPOUNDS 有权
标题翻译：吡咯烷酮化合物
公开(公告)号：US20120028951A1
公开(公告)日：2012-02-02
申请号：US13148172
申请日：2010-02-04
申请人： Takahiko Taniguchi , Akira Kawada , Mitsuyo Kondo , John F. Quinn , Jun Kunitomo , Masato Yoshikawa , Makoto Fushimi
发明人： Takahiko Taniguchi , Akira Kawada , Mitsuyo Kondo , John F. Quinn , Jun Kunitomo , Masato Yoshikawa , Makoto Fushimi
IPC分类号： A61K31/501 , C07D413/14 , C07D401/14 , C07D403/14 , A61P25/18 , C07D405/04 , C07D409/04 , C07D405/14 , C07D409/14 , A61K31/5377 , C07D403/04 , C07D413/04
CPC分类号： C07D403/04 , A61K9/2059 , C07D401/14 , C07D403/14 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/14 , C07D413/04 , C07D413/14
摘要： The present invention provides a compound which has the effect of PDE inhibition, and which is useful as a medicament for preventing or treating schizophrenia or so on. A compound of formula (I0), wherein R1 represents a substituent; R2 represents a hydrogen atom, or a substituent; R3 represents a hydrogen atom, or a substituent; Ring A represents an aromatic ring which can be substituted, and Ring B represents a 5-membered heteroaromatic ring which can be substituted, or a salt thereof.
摘要翻译：本发明提供具有PDE抑制作用的化合物，其可用作预防或治疗精神分裂症等的药物。式（I0）的化合物，其中R1表示取代基; R2表示氢原子或取代基; R3表示氢原子或取代基; 环A表示可被取代的芳环，环B表示可被取代的5元杂芳环或其盐。

45. 发明授权

US07438978B2 Transparent conductive film, transparent conductive plate, and touch panel 失效
标题翻译：透明导电膜，透明导电板和触摸屏
公开(公告)号：US07438978B2
公开(公告)日：2008-10-21
申请号：US11194848
申请日：2005-08-02
申请人： Hidefumi Kotsubo , Masato Yoshikawa , Yasuhiro Morimura , Kiyomi Sasaki
发明人： Hidefumi Kotsubo , Masato Yoshikawa , Yasuhiro Morimura , Kiyomi Sasaki
IPC分类号： B32B7/12 , B32B18/00 , B32B27/06 , B32B27/30 , B32B27/36
CPC分类号： B32B27/08 , B32B7/12 , B32B27/36 , B32B2038/0076 , B32B2307/202 , B32B2307/412 , B32B2367/00 , B32B2457/208 , G06F3/0488 , Y10T428/31678 , Y10T428/31681 , Y10T428/31786 , Y10T428/31797 , Y10T428/31928 , Y10T428/31935
摘要： A touch panel having excellent durability, in which depression is scarcely generated on the surface of the touch panel by pushing the surface with a pen, and a transparent conductive film and plate useful in the touch panel are provided. The transparent conductive film comprises a first polymer film having a transparent conductive thin layer thereon and a second polymer film having a hardcoat layer thereon, the first and second polymer films being bonded each other through an adhesive layer such that a surface having no transparent conductive thin layer of the first polymer film faces a surface having no hardcoat layer of the second polymer film, wherein work of the adhesive layer in elastic deformation is not less than 60%. The transparent conductive plate is provided with the adhesive layer, the touch panel is provided with the transparent conductive film or plate as an upper or lower electrode.
摘要翻译：提供了具有优异的耐久性的触摸面板，其中通过用笔推动表面几乎不在触摸面的表面上产生凹陷，并且提供了在触摸面板中有用的透明导电膜和板。透明导电膜包括其上具有透明导电薄层的第一聚合物膜和其上具有硬涂层的第二聚合物膜，第一和第二聚合物膜通过粘合剂层彼此接合，使得不具有透明导电薄膜第一聚合物膜的层面对不具有第二聚合物膜的硬涂层的表面，其中弹性变形中的粘合剂层的作用不小于60％。透明导电板设置有粘合剂层，触摸面板设置有作为上电极或下电极的透明导电膜或板。

46. 发明申请

US20080059601A1 Information Service System, Information Server, Portable Terminal, Information Service Control Program And Portable Terminal Control Program 审中-公开
标题翻译：信息服务系统，信息服务器，便携式终端，信息服务控制程序和便携式终端控制程序
公开(公告)号：US20080059601A1
公开(公告)日：2008-03-06
申请号：US11571145
申请日：2005-06-24
申请人： Masato Yoshikawa
发明人： Masato Yoshikawa
IPC分类号： G06F15/167
CPC分类号： H04L69/324
摘要： An information supply system in which in response to a request for information from a portable terminal (20) connected through a network (50), an information supply server (10) supplies the portable terminal (20) with the requested information, which system collates information requested by the portable terminal (20) with transmitted information which is held in the information supply server (10) to determine whether the information requested by the portable terminal (20) is already transmitted or not, thereby suppressing re-transmission of the information.
摘要翻译：一种信息提供系统，其中响应于来自通过网络（50）连接的便携式终端（20）的信息请求，信息提供服务器（10）向便携式终端（20）提供所请求的信息，该系统整理由便携式终端（20）请求的信息具有保存在信息提供服务器（10）中的发送信息，以确定便携式终端（20）请求的信息是否已被发送，从而抑制信息的重传。

47. 发明授权

US07329693B2 Adhesive composition and method for bonding to rubber 有权
标题翻译：粘合剂组合物和粘合橡胶的方法
公开(公告)号：US07329693B2
公开(公告)日：2008-02-12
申请号：US10478673
申请日：2002-05-22
申请人： Emil Giza , Masaaki Nakamura , Masato Yoshikawa
发明人： Emil Giza , Masaaki Nakamura , Masato Yoshikawa
IPC分类号： C08F2/46
CPC分类号： C09J109/00 , B60C1/00 , B60C9/00 , B60C9/0042 , C08J5/124 , C08J2321/00 , C08K5/17 , C08K5/18 , C08K5/29 , C08K5/34 , C08K5/405 , C09J115/00 , Y10T428/2852 , Y10T428/2883 , Y10T428/31826 , Y10T428/31855
摘要： An adhesive composition of the present invention comprises (A) a conjugated diene polymer having a weight-average molecular weight of 500 to 100,000 and (B) an electron pair-donating basic compound; or comprises (A) a conjugated diene polymer having a weight-average molecular weight of 500 to 100,000, (C) a compound having in its molecule three or more functional groups selected from the group consisting of acryloyloxy group, methacryloyloxy group and groups represented by the following formula I: wherein R1, R2 and m are the same as defined in the specification, and (D) a compound having in its molecule one or two functional groups selected from the group consisting of acryloyloxy group and methacryloyloxy group. At least a part of the surface of an adherend is coated with the adhesive composition to form an adhesive layer. After optionally irradiating the adhesive layer with ultraviolet light or radiation, the vulcanization is preformed while bringing an unvulcanized rubber into press-contact with the adhesive layer, thereby attaining a strong adhesion between the rubber and the adherend. The rubber/adherend composite thus produced is suitably used for the production of rubber-reinforcing materials and rubber articles.
摘要翻译：本发明的粘合剂组合物包含（A）重均分子量为500〜100,000的共轭二烯聚合物和（B）电子对给予碱性化合物; 或者包含（A）重均分子量为500〜100,000的共轭二烯系聚合物，（C）分子中具有选自由丙烯酰氧基，甲基丙烯酰氧基组成的组中的3个以上官能团的化合物和下式I：其中R 1，R 2和m与说明书中所定义的相同，和（D）在其分子中具有一个或两个官能团选自丙烯酰氧基和甲基丙烯酰氧基的基团。粘合剂组合物涂覆被粘物表面的至少一部分以形成粘合剂层。在可选地用紫外线或辐射照射粘合剂层之后，在使未硫化橡胶与粘合剂层压接的同时预硫化，从而在橡胶和被粘物之间获得牢固的粘合。由此制造的橡胶/被粘物组合物适合用于生产橡胶增强材料和橡胶制品。

48. 发明授权

US06665001B1 Multiplex and demultiplex controlling apparatus, multiplex and demultiplex controlling system, and method thereof 有权
标题翻译：多路复用和解复用控制装置，复用和解复用控制系统及其方法
公开(公告)号：US06665001B1
公开(公告)日：2003-12-16
申请号：US09464487
申请日：1999-12-15
申请人： Masato Yoshikawa
发明人： Masato Yoshikawa
IPC分类号： H04N714
CPC分类号： H04N21/4307 , H04N7/147 , H04N21/235 , H04N21/23614 , H04N21/4305 , H04N21/4348 , H04N21/435
摘要： Multiplexed image data and control data are demultiplexed from each other, and time information is added thereto, respectively, and the image data and control data are stored in temporary storage means, and the corresponding image data and control data are read out from the temporary storage means in accordance with synchronous timing corresponding to the time information which is added thereto, and a control processing is conducted in accordance with the control data while the image data is reproduced, and at the same time, the synchronous timing is corrected in response to a difference between the time information which is added to the image data and the time information which is added to the control data, and accordingly, it is possible to control an apparatus not only by means of synchronization with and a display of video voice but also synchronously with the video voice, and furthermore, it is possible to avoid a delay of synchronization between the video voice and a control device since the synchronous timing is corrected in response to a difference between processing periods of time.
摘要翻译：复用图像数据和控制数据彼此解复用，并且分别添加时间信息，并且将图像数据和控制数据存储在临时存储装置中，并且从临时存储器中读出相应的图像数据和控制数据根据与其相加的时间信息相对应的同步定时的装置，并且在再现图像数据的同时根据控制数据进行控制处理，并且同时响应于添加到图像数据的时间信息与添加到控制数据的时间信息之间的差异，因此，可以不仅通过与视频语音的同步和显示同时控制装置具有视频语音，此外，可以避免视频语音和控制偏差之间的同步延迟因为响应于处理时间段之间的差异来校正同步定时。

49. 发明授权

US5684913A Optical waveguide tube and method of making 失效
标题翻译：光波导管及其制作方法
公开(公告)号：US5684913A
公开(公告)日：1997-11-04
申请号：US576337
申请日：1995-12-21
申请人： Hideo Sugiyama , Masato Sugimachi , Masato Yoshikawa , Minoru Ishiharada , Itsuo Tanuma , Kazuo Naito , Atsushi Hotta
发明人： Hideo Sugiyama , Masato Sugimachi , Masato Yoshikawa , Minoru Ishiharada , Itsuo Tanuma , Kazuo Naito , Atsushi Hotta
IPC分类号： G02B1/04 , G02B6/09
CPC分类号： G02B6/02033 , G02B1/046
摘要： The invention relates to an optical waveguide tube comprising a tubular cladding filled with a solid core having a higher refractive index than the cladding. In one form, a resin material having a Tg of up to 50.degree. C. and a modulus of elasticity of up to 10.sup.9 dyne/cm.sup.2 is used as the core. In another form, a copolymer of acrylic acid, methacrylic acid or a lower alcohol ester thereof with a higher alkyl (meth)acrylate is used as the core, preferably in combination with a phosphate, aromatic carboxylate, aliphatic carboxylic acid, aliphatic carboxylate or glycol. In a third form, such an optical waveguide tube is prepared by filling a hollow tubular transparent cladding having opposite open ends with a liquid monomeric charge and causing the monomeric charge to polymerize while pressurizing the exposed surfaces of the monomeric charge inwardly from the opposite open ends along an axial direction of the cladding, thereby forming a core within the cladding.
摘要翻译：本发明涉及一种光波导管，其包括填充有具有比包层更高的折射率的实芯的管状包层。在一种形式中，使用Tg高达50℃，弹性模量高达109达因/ cm2的树脂材料作为核心。在另一种形式中，使用丙烯酸，甲基丙烯酸或其低级醇酯与高级（甲基）丙烯酸烷基酯的共聚物作为核心，优选与磷酸酯，芳族羧酸酯，脂族羧酸，脂族羧酸酯或二醇。在第三种形式中，这种光波导管通过用具有液体单体电荷填充具有相对开口端的中空管状透明包层来制备，并且使单体电荷聚合，同时将单体电荷的暴露表面从相对的开口端向内压沿着包层的轴向方向，由此在包层内形成一个芯。

50. 发明授权

US5557702A Light guide comprising a methacrylic or acrylic acid resin core and a fluorocarbon resin clad 失效
标题翻译：导光体包含甲基丙烯酸或丙烯酸树脂芯和氟碳树脂包层
公开(公告)号：US5557702A
公开(公告)日：1996-09-17
申请号：US356548
申请日：1994-12-15
申请人： Masato Yoshikawa , Minoru Ishiharada , Itsuo Tanuma , Kazuo Naito , Masato Sugimachi , Hideo Sugiyama
发明人： Masato Yoshikawa , Minoru Ishiharada , Itsuo Tanuma , Kazuo Naito , Masato Sugimachi , Hideo Sugiyama
IPC分类号： G02B1/04 , G02B6/00
CPC分类号： G02B6/02033 , G02B1/046 , G02B1/048 , Y10T428/139 , Y10T428/1393
摘要： A light guide includes a hollow tubular cladding of a fluorocarbon resin having a methacrylic or acrylic monomer graft polymerized inner surface. The cladding is integrally filled with a core of a methacrylic or acrylic resin which is polymerized to the graft polymerized surface.
摘要翻译：导光体包括具有甲基丙烯酸或丙烯酸单体接枝聚合内表面的氟碳树脂的中空管状包层。包层一体地填充有聚合到接枝聚合表面的甲基丙烯酸或丙烯酸树脂的芯。

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