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41. 发明授权

US08784367B2 Sensor and control unit for flow control and a method for controlled delivery of fluid 有权
标题翻译：用于流量控制的传感器和控制单元以及用于控制流体输送的方法
公开(公告)号：US08784367B2
公开(公告)日：2014-07-22
申请号：US13001798
申请日：2009-07-02
申请人： Ronald Dekker , Jaap Haartsen , Pascal De Graaf , Antoon Marie Henrie Tombeur , Adrianus Johannes Maria Van Tuijl
发明人： Ronald Dekker , Jaap Haartsen , Pascal De Graaf , Antoon Marie Henrie Tombeur , Adrianus Johannes Maria Van Tuijl
IPC分类号： A61M31/00 , G01F1/68
CPC分类号： G01F1/6888 , A61M5/16886 , A61M2205/3334 , A61M2205/3368 , G01F1/6847 , G01F1/696 , G01F15/005 , G01F15/14
摘要： The invention relates to a sensor (102) and a control unit (702) for cooperation with the sensor. The sensor (102) serves for measuring a velocity of a fluid (308) flowing through a channel (306). The sensor (102) employs a thermal measuring principle, which measuring principle is robust regarding disturbances on the amount of power dissipated by the heating element (106). A sensor receiver (110) is arranged for receiving an electromagnetic radiation generated by a control transmitter (722) comprised in a control (702) unit for cooperation with the sensor (102). The electromagnetic radiation is employed for powering the heating element (106) which is arranged for heating the fluid. On the basis of a measurement signal generated by a transducer arrangement comprised in the sensor (102), a control actuator (724) controls the velocity of the fluid. For this purpose a sensor transmitter (116) is arranged for transmitting the measurement signal to a control receiver (734).
摘要翻译：本发明涉及一种与传感器配合的传感器（102）和控制单元（702）。传感器（102）用于测量流过通道（306）的流体（308）的速度。传感器（102）采用热测量原理，其测量原理对于由加热元件（106）耗散的功率的干扰是鲁棒的。传感器接收器（110）布置成用于接收由包含在控制（702）单元中的控制发射器（722）产生的电磁辐射，用于与传感器（102）协作。电磁辐射用于为加热元件（106）提供动力，加热元件（106）用于加热流体。基于由包括在传感器（102）中的换能器装置产生的测量信号，控制致动器（724）控制流体的速度。为此，传感器发射器（116）被布置用于将测量信号发送到控制接收器（734）。

42. 发明授权

US08708922B2 Electrically isolated catheter with wireless sensors 有权
标题翻译：带有无线传感器的电隔离导管
公开(公告)号：US08708922B2
公开(公告)日：2014-04-29
申请号：US12519817
申请日：2007-12-19
申请人： Ronald Dekker , Antoon Marie Henrie Tombeur , Theodorus Martinus Michielsen
发明人： Ronald Dekker , Antoon Marie Henrie Tombeur , Theodorus Martinus Michielsen
IPC分类号： A61B5/04
CPC分类号： A61B5/0031 , A61B5/0215 , A61B5/027 , A61B5/03 , A61B5/042 , A61B5/1459 , A61B5/1473 , A61B2560/0219
摘要： A local power-delivery/data-reception unit is installed within an insertion end of a sealed catheter. The local power-delivery/data-reception unit wirelessly powers a separately sealed sensor that is attached to the insertion end and configured for wirelessly sending a data signal to the local power-delivery/data-reception unit. The catheter may further feature a remote power-delivery/data-reception unit disposed within the handle and configured for wirelessly communicating with the local power-delivery/data-reception unit and a controller for controlling the sensor.
摘要翻译：局部送电/数据接收单元安装在密封导管的插入端内。本地供电/数据接收单元无线地对附接到插入端的单独密封的传感器供电，并被配置为将数据信号无线发送到本地电力传送/数据接收单元。导管还可以具有设置在手柄内并被配置为与本地供电/数据接收单元无线通信的远程电力传送/数据接收单元和用于控制传感器的控制器。

43. 发明申请

US20140005521A1 CATHETER COMPRISING CAPACITIVE MICROMACHINED ULTRASONIC TRANSDUCERS WITH AN ADJUSTABLE FOCUS 有权
标题翻译：包含具有可调焦点的电容式微超声波超声波传感器的导管
公开(公告)号：US20140005521A1
公开(公告)日：2014-01-02
申请号：US13885791
申请日：2011-11-15
申请人： Max Oskar Köhler , Peter Dirksen , Shunmugavelu Sokka , Ronald Dekker
发明人： Max Oskar Köhler , Peter Dirksen , Shunmugavelu Sokka , Ronald Dekker
IPC分类号： A61N7/02 , A61B5/055 , A61B5/01 , A61B6/00 , A61B8/12 , A61B8/00 , A61B5/00 , A61B6/03
CPC分类号： A61B5/015 , A61B5/055 , A61B5/064 , A61B5/4836 , A61B6/03 , A61B6/12 , A61B6/4057 , A61B8/0841 , A61B8/12 , A61B8/445 , A61B8/4488 , A61B8/54 , A61B8/58 , A61B2018/00023 , A61B2090/064 , A61B2090/374 , A61B2562/028 , A61N7/022 , A61N2007/0095 , B06B1/0292 , G06F19/00
摘要： A catheter (700, 800, 1206) comprising: a shaft with distal (808, 906, 1004, 208) and proximal ends (1006),wherein the distal end comprises at least one array of capacitive micromachined ultrasound transducers (308, 402, 404, 500, 512, 600, 604, 802, 008) with an adjustable focus for controllably heating a target zone (806, 1014, 1210); and a connector (1012) at the proximal end for supplying the at least one array of capacitive micromachined ultrasound transducers with electrical power and for controlling the adjustable focus.
摘要翻译：导管（700,800,1206）包括：具有远端（808,906,1004,208）和近端（1006）的轴，其中所述远端包括至少一个电容微加工超声换能器阵列（308,402，具有可调焦点，用于可控制地加热目标区域（806,104,1210）; 以及在所述近端处的用于向所述至少一个电容微加工超声换能器阵列供电并用于控制所述可调焦点的连接器（1012）。

44. 发明授权

US08506793B2 Cardiomyocytes-containing device and method for manufacturing and using the same 失效
标题翻译：含有心肌细胞的装置及其制造和使用方法
公开(公告)号：US08506793B2
公开(公告)日：2013-08-13
申请号：US13147607
申请日：2010-02-02
申请人： Ronald Dekker , Anja Van De Stolpe
发明人： Ronald Dekker , Anja Van De Stolpe
IPC分类号： G01N27/327
CPC分类号： G01N1/30 , C12N5/0657 , C12N2503/02 , C12N2535/10 , G01N33/5061
摘要： Disclosed is a device for determining the cardiotoxicity of a chemical compound, comprising a substrate (10) carrying a deformable stack (34), said stack being partially detached from the substrate by a cavity (32) allowing an out-of-plane deformation of the stack, said stack comprising a first deformable layer (16), a second deformable layer (20) and a multi-electrode structure (18) sandwiched between the first and second deformable layers, the second deformable layer carrying a pattern of cardiomyocytes (28) adhered thereto; and a liquid container (26) mounted on the substrate for exposing the cardiomyocytes to the chemical compound. A method of manufacturing such a device is also disclosed. The present invention further relates to the use of the device for drug target discovery and/or drug development and a method for developing a disease model for a disease that is caused by or modified by stretching of cells, in particular a cardiac disease model.
摘要翻译：公开了一种用于确定化合物的心脏毒性的装置，包括承载可变形叠层（34）的基底（10），所述叠层通过空腔（32）部分地从基底分离，所述堆叠包括夹在所述第一和第二可变形层之间的第一可变形层（16），第二可变形层（20）和多电极结构（18），所述第二可变形层承载心肌细胞图案（28 ）和安装在基板上的用于将心肌细胞暴露于化合物的液体容器（26）。还公开了制造这种装置的方法。本发明还涉及该装置用于药物靶发现和/或药物开发的用途，以及用于开发由细胞拉伸，特别是心脏疾病模型引起或改变的疾病的疾病模型的方法。

45. 发明申请

US20120039565A1 Beam Combiner 有权
标题翻译：光束组合器
公开(公告)号：US20120039565A1
公开(公告)日：2012-02-16
申请号：US13208806
申请日：2011-08-12
申请人： Edwin Jan Klein , Ronald Dekker , Hindrik F. Bulthuis
发明人： Edwin Jan Klein , Ronald Dekker , Hindrik F. Bulthuis
IPC分类号： G02B6/12
CPC分类号： G02B6/12007 , G02B6/29332 , G02B6/2938 , G02B2006/12061 , G02B2006/12123 , G02B2006/12147
摘要： A beam combiner is disclosed that comprises a planar lightwave circuit that is based on undoped silicon nitride-based surface waveguides, wherein the planar lightwave circuit comprises a plurality of input ports, a mixing region, and an output port, and wherein the mixing region comprises a plurality of directional couplers that are arranged in a tree structure. Embodiments of the present invention are capable of combining a plurality of light signals characterized by disparate wavelengths on irregular spacings with low loss. Further, the present invention enables high-volume, low cost production of beam combiners capable of combining three or more light signals into a single composite output beam.
摘要翻译：公开了一种组合器，其包括基于未掺杂的基于氮化硅的表面波导的平面光波电路，其中所述平面光波电路包括多个输入端口，混合区域和输出端口，并且其中所述混合区域包括以树结构布置的多个定向耦合器。本发明的实施例能够以不同的波长以不同的间隔组合以不同波长表征的多个光信号，并具有低损耗。此外，本发明能够高容量，低成本地生产能够将三个或更多个光信号组合成单个复合输出光束的光束组合器。

46. 发明申请

US20120038032A1 FLEXIBLE DEVICE AND METHOD OF MANUFACTURING THE SAME 审中-公开
标题翻译：柔性装置及其制造方法
公开(公告)号：US20120038032A1
公开(公告)日：2012-02-16
申请号：US13279941
申请日：2011-10-24
申请人： Ronald Dekker , Theodorus Martinus Michielsen
发明人： Ronald Dekker , Theodorus Martinus Michielsen
IPC分类号： H01L29/06 , H01L21/56
CPC分类号： H01L27/12 , G02F1/133305 , G02F1/136227 , G02F1/167 , G02F2001/13613 , G02F2202/105 , H01L27/1214 , H01L27/1266 , H01L27/3244 , H01L51/524 , H01L51/5253 , H01L2221/6835 , H01L2221/68363 , H01L2251/5338
摘要： The rollable device of the invention comprises a substrate of an insulating material with apertures extending from a first to a second side. On the first side switching elements are present, as well as interconnect lines and the like, covered by a coating of organic material. On the second side a functional layer is present. Examples of such functional layers include capacitors, antennas and particularly electro-optical layers. Thus, with a rollable display that may include an antenna and a driver circuit is obtained.
摘要翻译：本发明的可滚动装置包括具有从第一侧延伸到第二侧的孔的绝缘材料的基底。在第一侧上存在开关元件以及由有机材料涂层覆盖的互连线等。在第二面上存在功能层。这些功能层的实例包括电容器，天线，特别是电光层。因此，可以获得可包括天线和驱动电路的可滚动显示器。

47. 发明申请

US20110118705A1 SENSOR AND CONTROL UNIT FOR FLOW CONTROL AND A METHOD FOR CONTROLLED DELIVERY OF FLUID 有权
标题翻译：用于流量控制的传感器和控制单元和用于控制流体输送的方法
公开(公告)号：US20110118705A1
公开(公告)日：2011-05-19
申请号：US13001798
申请日：2009-07-02
申请人： Ronald Dekker , Jaap Haartsen , Pascal De Graaf , Antoon Marie Henrie Tombeur , Adrianus Johannes Maria Van Tuijl
发明人： Ronald Dekker , Jaap Haartsen , Pascal De Graaf , Antoon Marie Henrie Tombeur , Adrianus Johannes Maria Van Tuijl
IPC分类号： A61M5/00 , G01F1/688
CPC分类号： G01F1/6888 , A61M5/16886 , A61M2205/3334 , A61M2205/3368 , G01F1/6847 , G01F1/696 , G01F15/005 , G01F15/14
摘要： The invention relates to a sensor (102) and a control unit (702) for cooperation with the sensor. The sensor (102) serves for measuring a velocity of a fluid (308) flowing through a channel (306). The sensor (102) employs a thermal measuring principle, which measuring principle is robust regarding disturbances on the amount of power dissipated by the heating element (106). A sensor receiver (110) is arranged for receiving an electromagnetic radiation generated by a control transmitter (722) comprised in a control (702) unit for cooperation with the sensor (102). The electromagnetic radiation is employed for powering the heating element (106) which is arranged for heating the fluid. On the basis of a measurement signal generated by a transducer arrangement comprised in the sensor (102), a control actuator (724) controls the velocity of the fluid. For this purpose a sensor transmitter (116) is arranged for transmitting the measurement signal to a control receiver (734).
摘要翻译：本发明涉及一种与传感器配合的传感器（102）和控制单元（702）。传感器（102）用于测量流过通道（306）的流体（308）的速度。传感器（102）采用热测量原理，其测量原理对于由加热元件（106）耗散的功率的干扰是鲁棒的。传感器接收器（110）布置成用于接收由包含在控制（702）单元中的控制发射器（722）产生的电磁辐射，用于与传感器（102）协作。电磁辐射用于为加热元件（106）提供动力，加热元件（106）用于加热流体。基于由包括在传感器（102）中的换能器装置产生的测量信号，控制致动器（724）控制流体的速度。为此，传感器发射器（116）被布置用于将测量信号发送到控制接收器（734）。

48. 发明申请

US20110094314A1 PRESSURE SENSOR, SENSOR PROBE COMPRISING A PRESSURE SENSOR, MEDICAL APPARATUS COMPRISING A SENSOR PROBE AND A METHOD OF FABRICATING A SENSOR PROBE 有权
标题翻译：压力传感器，包含压力传感器的传感器探测器，包含传感器探针的医疗装置和制造传感器探针的方法
公开(公告)号：US20110094314A1
公开(公告)日：2011-04-28
申请号：US12674439
申请日：2008-08-19
申请人： Ronald Dekker , Frederik Van Der Graaf , Johannes F.M. Velthuis , Jaap R. Haartsen
发明人： Ronald Dekker , Frederik Van Der Graaf , Johannes F.M. Velthuis , Jaap R. Haartsen
IPC分类号： G01L1/22
CPC分类号： G01L19/148 , G01L9/0042 , G01L19/0038 , H01L2224/24137
摘要： The invention relates to a pressure sensor comprising a flexible membrane deformable in response to a pressure, which covers a cavity (2) and which comprises a strain gauge (21) that produces signals corresponding to the deformation of the flexible membrane, wherein the flexible membrane is a flexible monolithic integrated circuit foil (10). In this way the semiconductor integrated circuit itself serves as the flexible membrane, leading to a less complex fabrication process.
摘要翻译：本发明涉及一种压力传感器，其包括响应于压力而可变形的柔性膜，所述压力传感器覆盖空腔（2）并且包括产生对应于柔性膜的变形的信号的应变仪（21），其中柔性膜是柔性单片集成电路箔（10）。以这种方式，半导体集成电路本身用作柔性膜，导致较不复杂的制造工艺。

49. 发明授权

US07816774B2 Flexible semiconductor device and identification label 有权
标题翻译：灵活的半导体器件和识别标签
公开(公告)号：US07816774B2
公开(公告)日：2010-10-19
申请号：US10563416
申请日：2004-07-01
申请人： Ronald Dekker , Theodorus Martinus Michielsen , Antoon Marie Henrie Tombeur , Pieter Werner Hooijmans
发明人： Ronald Dekker , Theodorus Martinus Michielsen , Antoon Marie Henrie Tombeur , Pieter Werner Hooijmans
IPC分类号： H01L23/02
CPC分类号： H01L21/6835 , G06K19/07749 , G06K19/0775 , H01L23/4985 , H01L23/49855 , H01L2221/68359 , H01L2221/68368 , H01L2924/0002 , H01L2924/12044 , H01L2924/19041 , H01L2924/3011 , H01Q1/38 , H01Q23/00 , Y10T29/49124 , H01L2924/00
摘要： A flexible device has an integrated circuit and an antenna incorporated or directly coupled to an interconnect structure of the integrated circuit. The interconnect structure extends outside of the active area. An electrically insulating or dielectric layer is present as support layer for both antenna and integrated circuit. The substrate is removed outside the active areas of the integrated circuit.
摘要翻译：柔性器件具有集成电路和天线，其集成或直接耦合到集成电路的互连结构。互连结构延伸到有效区域的外部。存在电绝缘或介电层作为天线和集成电路的支撑层。衬底被去除在集成电路的有源区域之外。

50. 发明申请

US20100078795A1 ELECTRONIC DEVICE 审中-公开
标题翻译：电子设备
公开(公告)号：US20100078795A1
公开(公告)日：2010-04-01
申请号：US11993516
申请日：2006-06-28
申请人： Ronald Dekker , Freddy Roozeboom , Peter Notten , Antonius Lucien Adrianus Maria Kemmeren
发明人： Ronald Dekker , Freddy Roozeboom , Peter Notten , Antonius Lucien Adrianus Maria Kemmeren
IPC分类号： H01L23/538 , H01L23/482
CPC分类号： H03H9/0547 , H01L25/16 , H01L27/14618 , H01L31/0203 , H01L2924/0002 , H03H9/105 , H01L2924/00
摘要： The electronic device comprises a semiconductor substrate (10) with at a first side (1) a circuit of semiconductor elements (20). The substrate (10) is present between a carrier (40) and an encapsulation (70), so that the first side (1) of the substrate (10) faces the carrier (40). The circuit of semiconductor elements (20) is coupled with conductor tracks (25) to a metallization (82) in a groove (80) in the encapsulation (70), which metallization (82) extends to terminals (90) at an outside of the encapsulation (70). At least one further electrical element (120) is defined between the first side (1) of the semiconductor substrate (10) and the encapsulation (70). This further element (120) is provided with at least one conductor track (65) extending to the metallization (82) in the groove (80) so as to incorporate the further element (120) in the circuit of semiconductor elements (20) on the first side (1) of the substrate (10).
摘要翻译：电子器件包括半导体衬底（10），在半导体元件（20）的第一侧（1）具有电路。衬底（10）存在于载体（40）和封装（70）之间，使得衬底（10）的第一侧（1）面向载体（40）。半导体元件（20）的电路与导体轨道（25）耦合到封装（70）中的凹槽（80）中的金属化（82），该金属化（82）延伸到端子（90）的外部封装（70）。在半导体衬底（10）的第一侧（1）和封装（70）之间限定至少一个另外的电元件（120）。这个另外的元件（120）设置有至少一个延伸到凹槽（80）中的金属化（82）的导体轨道（65），以便在半导体元件（20）的电路中并入另外的元件（120）衬底（10）的第一侧（1）。

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