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41. 发明申请

US20080319468A1 Biopsy device with selectable tissue receiving aperature orientation and site illumination 有权
标题翻译：具有选择性组织的活组织检查装置接收温度取向和位置照明
公开(公告)号：US20080319468A1
公开(公告)日：2008-12-25
申请号：US12229545
申请日：2008-08-25
申请人： Martin V. Shabaz , Richard L. Quick , Frank R. Louw , Paul Lubock , Jason H. Safabash
发明人： Martin V. Shabaz , Richard L. Quick , Frank R. Louw , Paul Lubock , Jason H. Safabash
IPC分类号： A61B10/02
CPC分类号： A61B10/0233 , A61B10/02 , A61B10/0266 , A61B10/0275 , A61B10/0283 , A61B17/32002 , A61B17/3417 , A61B90/30 , A61B90/39 , A61B2010/0208 , A61B2010/0225 , A61B2017/0046 , A61B2017/00473 , A61B2017/3405 , A61B2017/3454 , A61B2090/0811 , A61B2090/309 , B23Q17/2404 , F21V33/0068
摘要： The invention is directed to a system and device for separating and collecting a tissue specimen from a target site within a patient. The device includes a probe component with an elongated tubular section, a penetrating distal tip and a tissue receiving aperture in the distal end of the tubular section proximal to the distal tip, and a tissue cutting member which is slidably disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture by applying a vacuum to the inner lumen of the tissue cutting member. The device also has a driver component to which the probe component is releasably secured. The driver has a drive member for adjusting the orientation of the tubular section and thus the aperture therein and one or more drive members for moving the tissue cutting member within the tubular section to sever a tissue specimen from tissue extending into the interior of the tubular section through the aperture. The motion imparted to the tissue cutter is at least longitudinal and preferably is also oscillation and/or rotational to effectively separate a tissue specimen from tissue extending through the aperture in the tubular section.
摘要翻译：本发明涉及一种用于从患者内的目标部位分离和收集组织标本的系统和装置。该装置包括具有细长管状部分的探针部件，穿透远侧末端和在远端顶端的管状部分的远端中的组织接收孔，以及组织切割构件，其可滑动地设置在探针构件内以切割组织样本通过向组织切割构件的内腔施加真空而通过孔被拉入装置的内部。该装置还具有驱动器部件，探针组件可释放地固定到该部件上。驱动器具有用于调节管状部分的方向并因此调节其中的孔的驱动构件和一个或多个驱动构件，用于移动管状区段内的组织切割构件以将组织样本从延伸到管状部分内部的组织切断通过光圈。赋予组织切割器的运动至少是纵向的，并且优选也是振动和/或旋转以有效地将组织样本与延伸穿过管状部分中的孔的组织分离。

42. 发明申请

US20080132930A1 Tissue cutting member for a biopsy device 有权
标题翻译：用于活检装置的组织切割构件
公开(公告)号：US20080132930A1
公开(公告)日：2008-06-05
申请号：US11981292
申请日：2007-10-31
申请人： Paul Lubock , Frank R. Louw , Richard L. Quick
发明人： Paul Lubock , Frank R. Louw , Richard L. Quick
IPC分类号： A61B17/32
CPC分类号： A61B10/0275 , A61B10/0283 , A61B17/320016 , A61B17/3417
摘要： The invention is directed to tissue cutting members and biopsy devices with such tissue cutting member for separating a tissue specimen from a patient's body at a target site. The tissue cutting member is slidably disposed within an inner lumen of an elongated probe member of the biopsy device to cut a tissue specimen drawn into the interior of an outer cannula of the biopsy device through a tissue receiving aperture in the probe. The tissue cutting member has a tubular distal portion with a distal tip having an outer tissue cutting edge, an inner tissue receiving aperture, and a longitudinally oriented opening with a closed proximal end and open distal end which opens to the inner tissue receiving aperture to facilitate flaring of the distal tubular portion. The cutting member has at least one opening in a wall of the tubular portion to maintain a vacuum during use.
摘要翻译：本发明涉及具有这种组织切割构件的组织切割构件和活检装置，用于在目标部位处将组织标本与患者的身体分离。组织切割构件可滑动地设置在活检装置的细长探针构件的内腔中，以通过探针中的组织接收孔切割拉入活检装置的外套管内部的组织样本。组织切割构件具有管状远端部分，远侧末端具有外部组织切割边缘，内部组织接收孔和纵向定向的开口，其具有封闭的近端和敞开的远端，其通向内部组织接收孔以便于远端管状部分的扩口。切割构件在管状部分的壁中具有至少一个开口，以在使用期间保持真空。

43. 发明申请

US20080125644A1 MRI imageable assembly 审中-公开
标题翻译： MRI可成像组装
公开(公告)号：US20080125644A1
公开(公告)日：2008-05-29
申请号：US11978782
申请日：2007-10-30
申请人： Paul Lubock , Richard L. Quick , Ethan Broadaway
发明人： Paul Lubock , Richard L. Quick , Ethan Broadaway
IPC分类号： A61B5/055
CPC分类号： A61B17/3468 , A61B5/055 , A61B17/3498 , A61B90/39 , A61B2017/00477 , A61B2090/062 , A61B2090/3908 , A61B2090/3954 , A61B2090/3987
摘要： A marker delivery device is described which has an obturator with an elongated shaft, an inner lumen, a proximal end, and a substantially sealed distal end. One or more tissue markers are deployed within the inner lumen of the elongated shaft of the obturator. Preferably, the tissue marker(s) is disposed within an inner lumen of a marker delivery tube which is disposed within the inner lumen of the elongated shaft of the obturator. The marker delivery tube has an opening for discharging the tissue markers into a body (e.g. biopsy) cavity. The distal tip of the marker delivery tube is configured to penetrate the substantially sealed distal end of the obturator so that tissue markers can be delivered while the obturator is in place within the body. Preferably, the obturator includes a detectable element capable of producing a relatively significant image signature during MRI.
摘要翻译：描述了一种标记输送装置，其具有带有细长轴，内腔，近端和基本上密封的远端的闭塞器。一个或多个组织标记部署在闭塞器的细长轴的内腔内。优选地，组织标记设置在标记输送管的内腔内，该标记物输送管设置在闭塞器的细长轴的内腔内。标记物输送管具有用于将组织标记物排放到体内（例如活检）腔的开口。标记物输送管的远侧末端构造成穿透闭塞器的基本上密封的远端，使得组织标记物可以在闭塞器在体内就位的同时被输送。优选地，闭孔器包括能够在MRI期间产生相对显着的图像特征的可检测元件。

44. 发明授权

US07282034B2 Tissue accessing and anchoring device and method 有权
标题翻译：组织进入和锚定装置和方法
公开(公告)号：US07282034B2
公开(公告)日：2007-10-16
申请号：US10729086
申请日：2003-12-05
申请人： Fred H. Burbank , Paul Lubock , John Wardle , Frank Louw , Richard L. Quick
发明人： Fred H. Burbank , Paul Lubock , John Wardle , Frank Louw , Richard L. Quick
IPC分类号： A61B10/00
CPC分类号： A61B10/0266 , A61B6/4258 , A61B10/02 , A61B17/00491 , A61B18/1477 , A61B18/148 , A61B18/1482 , A61B18/1487 , A61B18/1815 , A61B90/39 , A61B2010/0208 , A61B2017/00115 , A61B2017/00867 , A61B2017/3488 , A61B2018/00208 , A61B2018/00273 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00916 , A61B2018/00958 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2090/378 , A61B2090/3904 , A61B2090/3908 , A61B2090/392
摘要： The invention provides systems, methods and a node accessing and anchoring device, comprising an elongated shaft, a tissue cutting member, at least one anchoring element extending from a position at or near the distal end of the shaft; and a radiation detector. The radiation detector is effective to locate and identify sentinel lymph nodes following injection of radioactive material into a primary lesion site within a patient. The tissue cutting member, which may be activated with radio frequency energy, is effective to allow access of the elongated shaft to a sentinel lymph node. The anchoring elements are effective to anchor the device to or adjacent a sentinel lymph node accessed by the device. Anchoring elements may assume radially, longitudinally, or mixed radially and longitudinally curved or coiled configurations when deployed.
摘要翻译：本发明提供系统，方法和节点访问和锚定装置，包括细长轴，组织切割构件，至少一个锚固元件，其从所述轴的远端处或附近的位置延伸; 和辐射探测器。放射线检测器在将放射性物质注入患者的原发性病变部位之后，有效地定位和识别前哨淋巴结。可以用射频能量激活的组织切割构件有效地允许细长轴进入前哨淋巴结。锚定元件有效地将装置锚定到或邻近由装置访问的前哨淋巴结。锚定元件在展开时可以呈径向，纵向或混合的径向和纵向弯曲或卷绕构型。

45. 发明授权

US07261712B2 Electrosurgical lesion location device 有权
标题翻译：电外科病变位置装置
公开(公告)号：US07261712B2
公开(公告)日：2007-08-28
申请号：US09967755
申请日：2001-09-28
申请人： Fred H. Burbank , Frank R. Louw , Paul Lubock , Richard L. Quick
发明人： Fred H. Burbank , Frank R. Louw , Paul Lubock , Richard L. Quick
IPC分类号： A61B18/18
CPC分类号： A61B10/0266 , A61B10/02 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/14 , A61B18/1477 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B90/39 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2090/3908
摘要： A device for localizing a target tissue mass in a body includes a tubular trocar portion having a distal end and a proximal end portion that is removably attachable to a handle portion. The trocar portion contains at least a first plurality of locator wires that are movable between a retracted position within the trocar and a deployed position extending radially from the trocar. In a preferred embodiment, the trocar portion has an electrosurgical cutting element at its distal end, and first and second pluralities of locator wires that, when deployed, respectively define first and second locating perimeters.
摘要翻译：用于使身体中的目标组织块定位的装置包括管状套管针部分，其具有可拆卸地附接到手柄部分的远端和近端部分。套针针部分包含至少第一组多个定位线，其可在套管针内的缩回位置和从套管针径向延伸的展开位置之间移动。在优选实施例中，套管针部分在其远端具有电外科切割元件，以及当展开时分别限定第一和第二定位周边的第一和第二多个定位线。

46. 发明授权

US06997885B2 Dilation devices and methods for removing tissue specimens 有权
公开(公告)号：US06997885B2
公开(公告)日：2006-02-14
申请号：US09916937
申请日：2001-07-27
申请人： Paul Lubock , Richard L. Quick
发明人： Paul Lubock , Richard L. Quick
IPC分类号： A61B10/00
CPC分类号： A61B10/0266 , A61B10/02 , A61B17/00491 , A61B17/0218 , A61B17/282 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B17/3439 , A61B18/14 , A61B18/1477 , A61B18/148 , A61B18/1482 , A61B18/1487 , A61B18/1492 , A61B90/02 , A61B90/37 , A61B90/39 , A61B2010/0208 , A61B2017/320064 , A61B2017/320733 , A61B2017/3484 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2018/1861 , A61B2090/3908
摘要： The invention provides devices and methods for use in removing tissue samples from within a patient's body. The devices include instruments having shafts for cutting a path to a tissue mass, and an inflatable balloon or balloons attached to the shaft effective to dilate the path upon inflation in order to aid in the removal of tissue masses from within the body of a patient. The devices also include instruments having dilation plates that may be inserted into a path leading to a tissue mass to be removed, and the plates separated effective to dilate the path to aid in the removal of tissue masses. Methods include inserting a device into a path leading to a tissue mass, and inflating a balloon or separating plates, thereby widening the path, and removing the tissue mass. Such devices and methods find use, for example, in biopsy and in lumpectomy procedures.

47. 发明授权

US06679851B2 Tissue accessing and anchoring device and method 有权
公开(公告)号：US06679851B2
公开(公告)日：2004-01-20
申请号：US09880218
申请日：2001-06-12
申请人： Fred H. Burbank , Paul Lubock , John Wardle , Frank Louw , Richard L. Quick
发明人： Fred H. Burbank , Paul Lubock , John Wardle , Frank Louw , Richard L. Quick
IPC分类号： A61B1000
CPC分类号： A61B10/0266 , A61B6/4258 , A61B10/02 , A61B17/00491 , A61B18/1477 , A61B18/148 , A61B18/1482 , A61B18/1487 , A61B18/1815 , A61B90/39 , A61B2010/0208 , A61B2017/00115 , A61B2017/00867 , A61B2017/3488 , A61B2018/00208 , A61B2018/00273 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00916 , A61B2018/00958 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2090/378 , A61B2090/3904 , A61B2090/3908 , A61B2090/392
摘要： The invention provides systems, methods and a node accessing and anchoring device, comprising an elongated shaft, a tissue cutting member, at least one anchoring element extending from a position at or near the distal end of the shaft; and a radiation detector. The radiation detector is effective to locate and identify sentinel lymph nodes following injection of radioactive material into a primary lesion site within a patient. The tissue cutting member, which may be activated with radio frequency energy, is effective to allow access of the elongated shaft to a sentinel lymph node. The anchoring elements are effective to anchor the device to or adjacent a sentinel lymph node accessed by the device. Anchoring elements may assume radially, longitudinally, or mixed radially and longitudinally curved or coiled configurations when deployed.

48. 发明授权

US06620157B1 High frequency power source 有权
标题翻译：高频电源
公开(公告)号：US06620157B1
公开(公告)日：2003-09-16
申请号：US09752978
申请日：2000-12-28
申请人： James Huntington Dabney , Richard L. Quick , Conrad Sawicz , Paul Lubock , Dan Kussman
发明人： James Huntington Dabney , Richard L. Quick , Conrad Sawicz , Paul Lubock , Dan Kussman
IPC分类号： A61B1818
CPC分类号： G01R31/025 , A61B18/042 , A61B18/1206 , A61B18/16 , A61B18/18 , A61B34/35 , A61B2018/00601 , A61B2018/00607 , A61B2018/00666 , A61B2018/00702 , A61B2018/00726 , A61B2018/00827 , A61B2018/00875 , A61B2018/00892 , A61B2018/00898 , A61B2018/0094 , A61B2018/1213 , A61B2018/1266 , A61B2018/1286 , A61B2018/162
摘要： A high frequency electrosurgical power generator configured to produce electrical power at a frequency of about 1 to about 14 MHz and preferably having an essentially sinusoidal waveform with a voltage level up to 1,000 Vrms, and a current level up to 5 Amps. The output of the high frequency electrosurgical power generator is connected to an electrosurgical tool configured to receive the voltage and current produced by the electrosurgical power generator and deliver the voltage and current to an electrosurgical site. The output of the electrosurgical generator preferably is an essentially sinusoid waveform with a frequency between about 3 MHz and about 8 MHz, up to about 700 volts rms, up to about 2 amps, with a total power of up to 1,000 watts.
摘要翻译：一种高频电外科发电机，其配置成以约1至约14MHz的频率产生电力，并且优选地具有基本上正弦波形，其电压电平高达1000Vrms，电流水平高达5安培。高频电外科发电机的输出连接到电外科手术工具，其被配置为接收由电外科发电机产生的电压和电流，并将电压和电流传递到电外科手术部位。电外科发生器的输出优选地是基本上是正弦波形，其频率在约3MHz至约8MHz之间，高达约700V rms，高达约2安培，总功率高达1,000瓦。

49. 发明授权

US09204866B2 Biopsy device with selectable tissue receiving aperture orientation and site illumination 有权
标题翻译：活组织检查装置，可选择组织接收孔径取向和局部照明
公开(公告)号：US09204866B2
公开(公告)日：2015-12-08
申请号：US12794480
申请日：2010-06-04
申请人： Martin V. Shabaz , Richard L. Quick , Frank R. Louw , Paul Lubock , Jason H. Safabash
发明人： Martin V. Shabaz , Richard L. Quick , Frank R. Louw , Paul Lubock , Jason H. Safabash
IPC分类号： A61B10/00 , A61B10/02 , A61B19/00 , F21V33/00 , B23Q17/24 , A61B17/32 , A61B17/34 , A61B17/00
CPC分类号： A61B10/0233 , A61B10/02 , A61B10/0266 , A61B10/0275 , A61B10/0283 , A61B17/32002 , A61B17/3417 , A61B90/30 , A61B90/39 , A61B2010/0208 , A61B2010/0225 , A61B2017/0046 , A61B2017/00473 , A61B2017/3405 , A61B2017/3454 , A61B2090/0811 , A61B2090/309 , B23Q17/2404 , F21V33/0068
摘要： The invention is directed to a system and device for separating and collecting a tissue specimen from a target site within a patient. The device includes a probe component with an elongated tubular section, a penetrating distal tip and a tissue receiving aperture in the distal end of the tubular section proximal to the distal tip, and a tissue cutting member which is slidably disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture by applying a vacuum to the inner lumen of the tissue cutting member. The device also has a driver component to which the probe component is releasably secured. The driver has a drive member for adjusting the orientation of the tubular section and thus the aperture therein and one or more drive members for moving the tissue cutting member within the tubular section to sever a tissue specimen from tissue extending into the interior of the tubular section through the aperture. The motion imparted to the tissue cutter is at least longitudinal and preferably is also oscillation and/or rotational to effectively separate a tissue specimen from tissue extending through the aperture in the tubular section.
摘要翻译：本发明涉及一种用于从患者内的目标部位分离和收集组织标本的系统和装置。该装置包括具有细长管状部分的探针部件，穿透远侧末端和在远端顶端的管状部分的远端中的组织接收孔，以及组织切割构件，其可滑动地设置在探针构件内以切割组织样本通过向组织切割构件的内腔施加真空而通过孔被拉入装置的内部。该装置还具有驱动器部件，探针组件可释放地固定到该部件上。驱动器具有用于调节管状部分的方向并因此调节其中的孔的驱动构件和一个或多个驱动构件，用于移动管状区段内的组织切割构件以将组织样本从延伸到管状部分内部的组织切断通过光圈。赋予组织切割器的运动至少是纵向的，并且优选也是振动和/或旋转以有效地将组织样本与延伸穿过管状部分中的孔的组织分离。

50. 发明授权

US08360990B2 Biopsy device with aperture orientation and improved tip 有权
公开(公告)号：US08360990B2
公开(公告)日：2013-01-29
申请号：US11981024
申请日：2007-10-31
申请人： Martin V. Shabaz , Richard L. Quick , Frank R. Louw , Paul Lubock , Jason H. Safabash
发明人： Martin V. Shabaz , Richard L. Quick , Frank R. Louw , Paul Lubock , Jason H. Safabash
IPC分类号： A61B10/00
CPC分类号： A61B10/0233 , A61B10/0275 , A61B10/0283 , A61B17/32002 , A61B17/32053 , A61B17/3417 , A61B2010/0208 , A61B2010/0225 , A61B2017/00473 , A61B2017/3405
摘要： The invention is directed to a system and device for separating and collecting a tissue specimen from a target site within a patient. The device includes a probe component which is releasably secured to the driver component. The probe component has an elongated tubular section, a penetrating distal tip and a tissue receiving aperture in the distal end of the tubular section proximal to the distal tip, and a tissue cutting member which is slidably disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture by applying a vacuum to the inner lumen of the tissue cutting member. The driver has drive members for operating the elements of the probe component. The tissue penetrating distal tip preferably has a triple concave curvature shape with three curved cutting edges leading to a sharp distal point.

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