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41. 发明授权

US06561998B1 Transluminal devices, systems and methods for enlarging interstitial penetration tracts 失效
公开(公告)号：US06561998B1
公开(公告)日：2003-05-13
申请号：US09056589
申请日：1998-04-07
申请人： Alex T. Roth , J. Christopher Flaherty , Adrian E. Johnson , Joshua Makower , Jason Brian Whitt
发明人： Alex T. Roth , J. Christopher Flaherty , Adrian E. Johnson , Joshua Makower , Jason Brian Whitt
IPC分类号： A61B1720
CPC分类号： A61B17/32075 , A61B17/32002 , A61B18/1482 , A61B18/245 , A61B2017/00252 , A61B2017/22069 , A61B2018/2255 , A61B2018/2266 , A61B2018/2272 , A61B2090/036 , A61B2090/065 , A61M25/104
摘要： Methods, apparatus and systems for enlarging interstitial penetration tracts which have been formed between blood vessels or elsewhere within the body of a mammalian patient. Included are debulking-type tract enlarging systems, dilation-type tract enlarging systems, tissue-slicing-type tract enlarging systems and two-catheter-type tract enlarging systems.

42. 发明授权

US06346074B1 Devices for less invasive intracardiac interventions 失效
标题翻译：器械侵入性较小的干预措施
公开(公告)号：US06346074B1
公开(公告)日：2002-02-12
申请号：US08662119
申请日：1996-06-12
申请人： Alex T. Roth
发明人： Alex T. Roth
IPC分类号： A61B106
CPC分类号： A61B17/0469 , A61B17/00234 , A61B17/0057 , A61B17/0218 , A61B17/0467 , A61B17/06061 , A61B17/2909 , A61B17/320016 , A61B17/3211 , A61B17/3417 , A61B17/3468 , A61B18/1442 , A61B18/1482 , A61B18/1492 , A61B90/37 , A61B90/50 , A61B2017/00053 , A61B2017/00243 , A61B2017/00247 , A61B2017/00349 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623 , A61B2017/00867 , A61B2017/00907 , A61B2017/0243 , A61B2017/047 , A61B2017/0472 , A61B2017/0474 , A61B2017/0475 , A61B2017/2943 , A61B2017/2946 , A61B2017/306 , A61B2017/3405 , A61B2017/3486 , A61B2017/3492 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00291 , A61B2018/00363 , A61B2018/00392 , A61B2018/00577 , A61B2018/00898 , A61B2018/00982 , A61B2018/1465 , A61F2/2427 , A61M25/1011 , A61M39/0247 , A61M2025/028 , A61M2039/0273 , A61M2039/0279 , A61M2039/0297 , A61M2205/3344 , A61M2205/3355 , A61M2205/366
摘要： Devices, systems, and methods are provided for accessing the interior of the heart and performing procedures therein while the heart is beating. In one embodiment, a tubular access device having an inner lumen is provided for positioning through a penetration in a muscular wall of the heart, the access device having a means for sealing within the penetration to inhibit leakage of blood through the penetration. The sealing means may comprise a balloon or flange on the access device, or a suture placed in the heart wall to gather the heart tissue against the access device. An obturator is removably positionable in the inner lumen of the access device, the obturator having a cutting means at its distal end for penetrating the muscular wall of the heart. The access device is preferably positioned through an intercostal space and through the muscular wall of the heart. Elongated instruments may be introduced through the tubular access device into an interior chamber of the heart to perform procedures such as septal defect repair and electrophysiological mapping and ablation. A method of septal defect repair includes positioning a tubular access device percutaneously through an intercostal space and through a penetration in a muscular wall of the heart, passing one or more instruments through an inner lumen of the tubular access device into an interior chamber of the heart, and using the instruments to close the septal defect. Devices and methods for closing the septal defect with either sutures or with patch-type devices are disclosed.
摘要翻译：提供了设备，系统和方法，用于访问心脏内部并在心脏跳动时执行其中的过程。在一个实施例中，提供具有内腔的管状进入装置用于通过心脏的肌肉壁中的穿透进行定位，所述进入装置具有用于密封穿透物的装置，以阻止血液渗透穿透。密封装置可以包括进入装置上的球囊或凸缘，或者放置在心壁中的缝合线，以将心脏组织收集在接近装置上。闭塞器可拆卸地定位在进入装置的内腔中，封闭器在其远端具有用于穿透心脏肌肉壁的切割装置。进入装置优选地通过肋间空间并穿过心脏的肌肉壁定位。细长的仪器可以通过管状进入装置引入心脏的内腔，以执行诸如间隔缺损修复和电生理测绘和消融的过程。间隔缺损修复的方法包括经由肋间空间穿过管状进入装置并穿过心脏的肌肉壁的穿透，使一个或多个器械通过管状进入装置的内腔进入心脏的内部腔室，并使用仪器封闭隔膜缺损。公开了用缝线或贴片式装置封闭隔膜缺损的装置和方法。

43. 发明授权

US5823956A Method and apparatus for thoracoscopic intracardiac procedures 失效
公开(公告)号：US5823956A
公开(公告)日：1998-10-20
申请号：US646210
申请日：1996-05-07
申请人： Alex T. Roth , Hanson S. Gifford
发明人： Alex T. Roth , Hanson S. Gifford
IPC分类号： A61B5/0444 , A61B1/00 , A61B5/0402 , A61B17/00 , A61B17/02 , A61B17/04 , A61B17/06 , A61B17/28 , A61B17/30 , A61B17/32 , A61B17/34 , A61B18/00 , A61B18/14 , A61B19/00 , A61F2/24 , A61F2/958 , A61M1/00 , A61B5/04 , A61B17/39 , A61N1/05
CPC分类号： A61B17/00234 , A61B17/0057 , A61B17/0218 , A61B17/0469 , A61B17/06061 , A61B17/320016 , A61B17/3468 , A61B18/1482 , A61B18/1492 , A61B90/50 , A61F2/2427 , A61M25/1011 , A61M39/0247 , A61B17/0467 , A61B17/2909 , A61B17/3211 , A61B17/3417 , A61B18/1442 , A61B2017/00053 , A61B2017/00243 , A61B2017/00247 , A61B2017/00349 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623 , A61B2017/00867 , A61B2017/00907 , A61B2017/0243 , A61B2017/047 , A61B2017/0472 , A61B2017/0474 , A61B2017/0475 , A61B2017/2943 , A61B2017/2946 , A61B2017/306 , A61B2017/3405 , A61B2017/3486 , A61B2017/3492 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00291 , A61B2018/00363 , A61B2018/00392 , A61B2018/00577 , A61B2018/00898 , A61B2018/00982 , A61B2018/1465 , A61B90/37 , A61M2025/028 , A61M2039/0279 , A61M2039/0297 , A61M2205/3344 , A61M2205/3355 , A61M2205/366 , Y10S623/904
摘要： Devices, systems, and methods are provided for accessing the interior of the heart and performing procedures therein while the heart is beating. In one embodiment, a tubular access device having an inner lumen is provided for positioning through a penetration in a muscular wall of the heart, the access device having a means for sealing within the penetration to inhibit leakage of blood through the penetration. The sealing means may comprise a balloon or flange on the access device, or a suture placed in the heart wall to gather the heart tissue against the access device. An obturator is removably positionable in the inner lumen of the access device, the obturator having a cutting means at its distal end for penetrating the muscular wall of the heart. The access device is preferably positioned through an intercostal space and through the muscular wall of the heart. Elongated instruments may be introduced through the tubular access device into an interior chamber of the heart to perform procedures such as septal defect repair and electrophysiological mapping and ablation. A method of septal defect repair includes positioning a tubular access device percutaneously through an intercostal space and through a penetration in a muscular wall of the heart, passing one or more instruments through an inner lumen of the tubular access device into an interior chamber of the heart, and using the instruments to close the septal defect. Devices and methods for closing the septal defect with either sutures or with patch-type devices are disclosed.

44. 发明授权

US5797960A Method and apparatus for thoracoscopic intracardiac procedures 失效
公开(公告)号：US5797960A
公开(公告)日：1998-08-25
申请号：US425179
申请日：1995-04-20
申请人： John H. Stevens , Bruce A. Reitz , Alex T. Roth , William S. Peters , Hanson S. Gifford
发明人： John H. Stevens , Bruce A. Reitz , Alex T. Roth , William S. Peters , Hanson S. Gifford
IPC分类号： A61B5/0444 , A61B1/00 , A61B5/0402 , A61B17/00 , A61B17/02 , A61B17/04 , A61B17/06 , A61B17/28 , A61B17/30 , A61B17/32 , A61B17/34 , A61B18/00 , A61B18/14 , A61B19/00 , A61F2/24 , A61F2/958 , A61M1/00 , A61M29/00
CPC分类号： A61B17/00234 , A61B17/0057 , A61B17/0218 , A61B17/0469 , A61B17/06061 , A61B17/320016 , A61B17/3468 , A61B18/1482 , A61B18/1492 , A61B90/50 , A61F2/2427 , A61M25/1011 , A61M39/0247 , A61B17/0467 , A61B17/2909 , A61B17/3211 , A61B17/3417 , A61B18/1442 , A61B2017/00053 , A61B2017/00243 , A61B2017/00247 , A61B2017/00349 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623 , A61B2017/00867 , A61B2017/00907 , A61B2017/0243 , A61B2017/047 , A61B2017/0472 , A61B2017/0474 , A61B2017/0475 , A61B2017/2943 , A61B2017/2946 , A61B2017/306 , A61B2017/3405 , A61B2017/3486 , A61B2017/3492 , A61B2018/00214 , A61B2018/00232 , A61B2018/00261 , A61B2018/00291 , A61B2018/00363 , A61B2018/00392 , A61B2018/00577 , A61B2018/00898 , A61B2018/00982 , A61B2018/1465 , A61B90/37 , A61M2025/028 , A61M2039/0279 , A61M2039/0297 , A61M2205/3344 , A61M2205/3355 , A61M2205/366 , Y10S623/904
摘要： Devices, systems, and methods are provided for accessing the interior of the heart and performing procedures therein while the heart is beating. In one embodiment, a tubular access device having an inner lumen is provided for positioning through a penetration in a muscular wall of the heart, the access device having a means for sealing within the penetration to inhibit leakage of blood through the penetration. The sealing means may comprise a balloon or flange on the access device, or a suture placed in the heart wall to gather the heart tissue against the access device. An obturator is removably positionable in the inner lumen of the access device, the obturator having a cutting means at its distal end for penetrating the muscular wall of the heart. The access device is preferably positioned through an intercostal space and through the muscular wall of the heart. Elongated instruments may be introduced through the tubular access device into an interior chamber of the heart to perform procedures such as septal defect repair and electrophysiological mapping and ablation. A method of septal defect repair includes positioning a tubular access device percutaneously through an intercostal space and through a penetration in a muscular wall of the heart, passing one or more instruments through an inner lumen of the tubular access device into an interior chamber of the heart, and using the instruments to close the septal defect. Devices and methods for closing the septal defect with either sutures or with patch-type devices are disclosed.

45. 外观设计

USD394109S Bi-leaf surgical instrument handle 失效
公开(公告)号：USD394109S
公开(公告)日：1998-05-05
申请号：US062408
申请日：1996-11-04
申请人： Scott H. Miller , Alex T. Roth
设计人： Scott H. Miller , Alex T. Roth

46. 发明授权

US08403839B2 Remote tissue retraction device 有权
公开(公告)号：US08403839B2
公开(公告)日：2013-03-26
申请号：US11955036
申请日：2007-12-12
申请人： Alex T. Roth , Craig Gerbi , Andrew H. Hancock , Gary Weller , Christopher Julian , James Gannoe
发明人： Alex T. Roth , Craig Gerbi , Andrew H. Hancock , Gary Weller , Christopher Julian , James Gannoe
IPC分类号： A61B1/32
CPC分类号： A61B17/0218 , A61B17/072 , A61B2017/003 , A61B2017/00314 , A61B2017/00323 , A61B2017/00827 , A61B2017/07214 , A61B2017/306
摘要： A medical device for managing tissue in an organ, such as the stomach, for retracting or positioning tissue and related organs to allow certain regions of the stomach to be acquired for a gastroplasty procedure. The medical device includes an elongated body having a proximal end and a distal end, and a tissue treatment device attached to the distal end of the elongated body. The tissue treatment device includes a first jaw opposite a second jaw, and each jaw is adapted to acquire tissue. A retractor is disposed along the tissue treatment device and adapted to be moveable from a delivery position to a retraction position to move or manage the tissue of the stomach. The medical device also includes a collapsible barrier disposed between the first and second jaws of the tissue treatment device to direct tissue into the first and second jaws separately.

47. 发明授权

US08357174B2 Single fold device for tissue fixation 有权
公开(公告)号：US08357174B2
公开(公告)日：2013-01-22
申请号：US13049628
申请日：2011-03-16
申请人： Alex T. Roth , Andrew H. Hancock , Gary Weller , Gilbert Mata, Jr. , Craig Gerbi , James Gannoe , Christopher Julian
发明人： Alex T. Roth , Andrew H. Hancock , Gary Weller , Gilbert Mata, Jr. , Craig Gerbi , James Gannoe , Christopher Julian
IPC分类号： A61B17/08 , A61B17/04
CPC分类号： A61F5/0083 , A61B1/3132 , A61B17/07207 , A61B17/1114 , A61B17/29 , A61B2017/00278 , A61B2017/003 , A61B2017/00323 , A61B2017/0034 , A61B2017/00353 , A61B2017/00876 , A61B2017/00946 , A61B2017/07214 , A61B2017/1103 , A61B2017/2905 , A61B2017/306 , A61B2090/08021 , A61F5/005 , A61F5/0076
摘要： A system for tissue approximation and fixation is described herein. A device is advanced in a minimally invasive manner within a patient's body to create one or several divisions or plications within a hollow body organ. The system comprises a stapler assembly having a tissue acquisition member and a tissue fixation member. The stapler assembly approximates tissue from within the hollow body organ with the acquisition member and then affixes the approximated tissue with the fixation member. In one method, the system can be used as a secondary procedure to reduce the size of a stoma within the hollow body organ.

48. 发明申请

US20120303005A1 Torque Shaft and Torque Drive 审中-公开
标题翻译：扭矩轴和扭矩传动
公开(公告)号：US20120303005A1
公开(公告)日：2012-11-29
申请号：US13569090
申请日：2012-08-07
申请人： David C. Forster , Brian Beckey , Brandon Walsh , Scott Heneveld , Alex T. Roth
发明人： David C. Forster , Brian Beckey , Brandon Walsh , Scott Heneveld , Alex T. Roth
IPC分类号： A61B17/00 , F16D3/00 , F16C1/04 , F16B17/00
CPC分类号： A61M25/0113 , A61F2/2427 , A61M25/0043 , A61M25/0138 , A61M25/0147 , F16C1/04 , F16C2226/78 , F16C2316/10 , Y10T403/70 , Y10T403/7045 , Y10T403/7073
摘要： Torque shafts and other related systems and methods are described herein. The torque shafts are both flexible and capable of transmitting torque. The torque shafts are useful for procedures that require torque and pushability to drive or deploy a device. The flexibility and pushability of the torque shafts enable them to curve along a tortuous path, and the torque transferring capability of the shafts enable them to transmit torque along the shaft.
摘要翻译：本文描述了扭矩轴和其它相关的系统和方法。扭矩轴既灵活又能够传递扭矩。扭矩轴对于要求扭矩和推动性来驱动或部署设备的过程非常有用。扭矩轴的灵活性和推力使其能够沿着曲折的路径弯曲，并且轴的转矩传递能力使得它们能够沿轴传递扭矩。

49. 发明申请

US20120095536A1 METHOD AND SYSTEM FOR CONTROL OF A PATIENT'S BODY TEMPERATURE BY WAY OF A TRANSLUMINALLY INSERTABLE HEAT EXCHANGE CATHETER 审中-公开
标题翻译：方法和系统通过一个透明的热交换导管的方式控制患者身体温度
公开(公告)号：US20120095536A1
公开(公告)日：2012-04-19
申请号：US13164648
申请日：2011-06-20
申请人： Timothy R. Machold , Wade A. Keller , Alex T. Roth , Nicole Denise Bloom
发明人： Timothy R. Machold , Wade A. Keller , Alex T. Roth , Nicole Denise Bloom
IPC分类号： A61F7/12
CPC分类号： A61F7/0085 , A61B2017/00092 , A61B2017/00119 , A61B2017/00123 , A61B2017/00199 , A61B2017/22051 , A61F7/0097 , A61F7/10 , A61F7/123 , A61F2007/0054 , A61F2007/0096 , A61F2007/126 , A61M25/10 , A61M25/1011 , A61M2025/1072 , A61M2025/1086 , A61M2205/12 , A61M2205/127
摘要： Methods and apparatuses for temperature modification of a patient, or selected regions thereof, including an induced state of hypothermia. The temperature modification is accomplished using an in-dwelling heat exchange catheter within which a fluid heat exchange medium circulates. A heat exchange cassette of any one of several disclosed variations is attached to the circulatory conduits of the catheter, the heat exchange cassette being sized to engage a cavity within one of various described re-usable control units. The control units include a heater/cooler device, a user input device, and a processor connected to receive input from various sensors around the body and the system. The heater/cooler device may be thermoelectric to enable both heating and 15″ cooling based on polarity. A temperature control scheme for ramping the body temperature up or down without overshoot is provided. The disposable heat exchange cassettes may include an integral pump head that engages with a pump drive mechanism within the re-usable control unit. More than one control unit may be provided to receive the same heat exchange cassette so that, for example, a large capacity control unit can be used initially, and a smaller, battery-powered unit can be substituted once the patient reaches the desired target temperature.
摘要翻译：包括诱导低温的状态的患者的温度改变方法和装置，或其选定区域。使用在其中流体热交换介质循环的内部热交换导管来实现温度改变。几个公开的变型中的任何一个的热交换盒附接到导管的循环导管，热交换盒的尺寸适于接合各种所描述的可重复使用的控制单元之一内的空腔。控制单元包括加热器/冷却器装置，用户输入装置和连接以接收来自身体和系统周围的各种传感器的输入的处理器。加热器/冷却器装置可以是热电，以使得能够基于极性进行加热和15“冷却。提供了一种用于使体温上升或下降而没有过冲的温度控制方案。一次性热交换盒可以包括与可再使用的控制单元内的泵驱动机构接合的整体泵头。可以提供多于一个控制单元以接收相同的热交换盒，使得例如最初可以使用大容量控制单元，并且一旦患者达到期望的目标温度，可以取代较小的电池供电的单元。

50. 发明申请

US20120083657A1 Remote Tissue Retraction Device 审中-公开
标题翻译：远程组织退缩装置
公开(公告)号：US20120083657A1
公开(公告)日：2012-04-05
申请号：US13326709
申请日：2011-12-15
申请人： Alex T. Roth , Craig Gerbi , Andrew H. Hancock , Gary Weller , Christopher Julian , James Gannoe
发明人： Alex T. Roth , Craig Gerbi , Andrew H. Hancock , Gary Weller , Christopher Julian , James Gannoe
IPC分类号： A61B1/32
CPC分类号： A61B17/0218 , A61B17/072 , A61B2017/003 , A61B2017/00314 , A61B2017/00323 , A61B2017/00827 , A61B2017/07214 , A61B2017/306
摘要： A medical device for managing tissue in an organ, such as the stomach, for retracting or positioning tissue and related organs to allow certain regions of the stomach to be acquired for a gastroplasty procedure. The medical device includes an elongated body having a proximal end and a distal end, and a tissue treatment device attached to the distal end of the elongated body. The tissue treatment device includes a first jaw opposite a second jaw, and each jaw is adapted to acquire tissue. A retractor is disposed along the tissue treatment device and adapted to be moveable from a delivery position to a retraction position to move or manage the tissue of the stomach. The medical device also includes a collapsible barrier disposed between the first and second jaws of the tissue treatment device to direct tissue into the first and second jaws separately.
摘要翻译：用于管理诸如胃的器官中的组织的医疗装置，用于缩回或定位组织和相关器官，以允许为胃成形术获得胃的某些区域。医疗装置包括具有近端和远端的细长主体，以及连接到细长主体的远端的组织处理装置。组织处理装置包括与第二钳口相对的第一钳口，并且每个钳口适于获取组织。牵开器沿着组织处理装置设置并适于从输送位置移动到缩回位置以移动或管理胃的组织。医疗装置还包括设置在组织处理装置的第一和第二钳口之间的可折叠屏障，以将组织分别引导到第一和第二钳口中。

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