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41. 发明申请

US20080097543A1 Cardiac rhythm management system and method 有权
标题翻译：心律管理系统及方法
公开(公告)号：US20080097543A1
公开(公告)日：2008-04-24
申请号：US12001154
申请日：2007-12-10
申请人： Qingsheng Zhu , Avram Scheiner
发明人： Qingsheng Zhu , Avram Scheiner
IPC分类号： A61N1/362
CPC分类号： A61N1/3712
摘要： A system and method for cardiac rhythm management, which includes an electrode system having at least one electrode and control circuitry coupled to the electrode system from which a first cardiac signal is sensed. The control circuitry includes a pulse circuit to produce electrical pulses at a first value to be delivered to the electrode system in a first cardiac region. At least one cardiac signal is sensed from a second cardiac region, where the cardiac signal includes indications of cardiac depolarizations from the second cardiac region which occurs in direct reaction to the electrical pulses delivered to the first cardiac region. The first value of the electrical pulses are then modified by a pulse adjustment circuit when a cardiac depolarization which occurs in direct reaction to the electrical pulse delivered to the first cardiac region is detected from the second cardiac region.
摘要翻译：一种用于心律管理的系统和方法，其包括具有耦合到所述电极系统的至少一个电极和控制电路的电极系统，从所述电极系统感测到第一心脏信号。控制电路包括脉冲电路，以在第一心脏区域产生将被传送到电极系统的第一值的电脉冲。从第二心脏区域感测至少一个心脏信号，其中心脏信号包括来自第二心脏区域的心脏去极化的指示，其发生在与递送至第一心脏区域的电脉冲直接反应中。当从第二心脏区域检测到与传送到第一心脏区域的电脉冲直接反应发生的心脏去极化时，脉冲调节电路修改电脉冲的第一值。

42. 发明授权

US08478391B2 Apparatus and method for outputting heart sounds 有权
公开(公告)号：US08478391B2
公开(公告)日：2013-07-02
申请号：US13456795
申请日：2012-04-26
申请人： Avram Scheiner , Qingsheng Zhu , Arthur L. Olive , Don Villalta
发明人： Avram Scheiner , Qingsheng Zhu , Arthur L. Olive , Don Villalta
IPC分类号： A61B5/025
CPC分类号： A61B7/04 , A61B5/0002 , A61B5/0031 , A61B5/04012 , A61B5/04014 , A61B5/0402 , A61B5/042 , A61B5/044 , A61B5/0452 , A61B5/1118 , A61B5/742 , A61B7/023 , G06F19/00
摘要： An apparatus for outputting heart sounds includes an implantable system and an external system. The implantable system includes a sensor for generating sensed signals representing detected heart sounds, an interface circuit and a control circuit for receiving the sensed signals, generating data representing the heart sounds therefrom, and transmitting the data to the external system via the interface circuit. The external system includes an interface circuit for communicating with the implantable system, and a control circuit for receiving the data representing the heart sounds and for generating control signals that cause an output device to generate outputs representing the sounds. The implantable system may also include a sensor(s) for detecting cardiac electrical signals. In this case, outputs representing the cardiac electrical signals are also output.

43. 发明授权

US08167811B2 Apparatus and method for outputting heart sounds 有权
标题翻译：用于输出心音的装置和方法
公开(公告)号：US08167811B2
公开(公告)日：2012-05-01
申请号：US13004543
申请日：2011-01-11
申请人： Avram Scheiner , Qingsheng Zhu , Arthur L. Olive , Don Villalta
发明人： Avram Scheiner , Qingsheng Zhu , Arthur L. Olive , Don Villalta
IPC分类号： A61B5/02
CPC分类号： A61B7/04 , A61B5/0002 , A61B5/0031 , A61B5/04012 , A61B5/04014 , A61B5/0402 , A61B5/042 , A61B5/044 , A61B5/0452 , A61B5/1118 , A61B5/742 , A61B7/023 , G06F19/00
摘要： An apparatus for outputting heart sounds includes an implantable system and an external system. The implantable system includes a sensor for generating sensed signals representing detected heart sounds, an interface circuit and a control circuit for receiving the sensed signals, generating data representing the heart sounds therefrom, and transmitting the data to the external system via the interface circuit. The external system includes an interface circuit for communicating with the implantable system, and a control circuit for receiving the data representing the heart sounds and for generating control signals that cause an output device to generate outputs representing the sounds. The implantable system may also include a sensor(s) for detecting cardiac electrical signals. In this case, outputs representing the cardiac electrical signals are also output.
摘要翻译：用于输出心音的装置包括可植入系统和外部系统。可植入系统包括用于产生表示检测到的心音的感测信号的传感器，接口电路和用于接收感测信号的控制电路，产生表示心音的数据，以及经由接口电路将数据发送到外部系统。外部系统包括用于与可植入系统进行通信的接口电路，以及用于接收表示心脏声音的数据的控制电路，以及用于产生使输出设备产生表示声音的输出的控制信号。可植入系统还可以包括用于检测心脏电信号的传感器。在这种情况下，还输出表示心电信号的输出。

44. 发明申请

US20110105933A1 APPARATUS AND METHOD FOR OUTPUTTING HEART SOUNDS 有权
标题翻译：用于输出心脏声音的装置和方法
公开(公告)号：US20110105933A1
公开(公告)日：2011-05-05
申请号：US13004543
申请日：2011-01-11
申请人： Avram Scheiner , Qingsheng Zhu , Arthur L. Olive , Don Villalta
发明人： Avram Scheiner , Qingsheng Zhu , Arthur L. Olive , Don Villalta
IPC分类号： A61B5/02
CPC分类号： A61B7/04 , A61B5/0002 , A61B5/0031 , A61B5/04012 , A61B5/04014 , A61B5/0402 , A61B5/042 , A61B5/044 , A61B5/0452 , A61B5/1118 , A61B5/742 , A61B7/023 , G06F19/00
摘要： An apparatus for outputting heart sounds includes an implantable system and an external system. The implantable system includes a sensor for generating sensed signals representing detected heart sounds, an interface circuit and a control circuit for receiving the sensed signals, generating data representing the heart sounds therefrom, and transmitting the data to the external system via the interface circuit. The external system includes an interface circuit for communicating with the implantable system, and a control circuit for receiving the data representing the heart sounds and for generating control signals that cause an output device to generate outputs representing the sounds. The implantable system may also include a sensor(s) for detecting cardiac electrical signals. In this case, outputs representing the cardiac electrical signals are also output.
摘要翻译：用于输出心音的装置包括可植入系统和外部系统。可植入系统包括用于产生表示检测到的心音的感测信号的传感器，接口电路和用于接收感测信号的控制电路，产生表示心音的数据，以及经由接口电路将数据发送到外部系统。外部系统包括用于与可植入系统进行通信的接口电路，以及用于接收表示心脏声音的数据的控制电路，以及用于产生使输出设备产生表示声音的输出的控制信号。可植入系统还可以包括用于检测心脏电信号的传感器。在这种情况下，还输出表示心电信号的输出。

45. 发明授权

US06363281B1 Cardiac rhythm management system and method 有权
标题翻译：心律管理系统及方法
公开(公告)号：US06363281B1
公开(公告)日：2002-03-26
申请号：US09571786
申请日：2000-05-16
申请人： Qingsheng Zhu , Avram Scheiner
发明人： Qingsheng Zhu , Avram Scheiner
IPC分类号： A61N137
CPC分类号： A61N1/3712
摘要： A system and method for cardiac rhythm management, which includes an electrode system having at least one electrode and control circuitry coupled to the electrode system from which a first cardiac signal is sensed. The control circuitry includes a pulse circuit to produce electrical pulses at a first value to be delivered to the electrode system in a first cardiac region. At least one cardiac signal is sensed from a second cardiac region, where the cardiac signal includes indications of cardiac depolarizations from the second cardiac region which occurs in direct reaction to the electrical pulses delivered to the first cardiac region. The first value of the electrical pulses are then modified by a pulse adjustment circuit when a cardiac depolarization which occurs in direct reaction to the electrical pulse delivered to the first cardiac region is detected from the second cardiac region.
摘要翻译：一种用于心律管理的系统和方法，其包括具有耦合到所述电极系统的至少一个电极和控制电路的电极系统，从所述电极系统感测到第一心脏信号。控制电路包括脉冲电路，以在第一心脏区域产生将被传送到电极系统的第一值的电脉冲。从第二心脏区域感测至少一个心脏信号，其中心脏信号包括来自第二心脏区域的心脏去极化的指示，其发生在与递送至第一心脏区域的电脉冲直接反应中。当从第二心脏区域检测到与传送到第一心脏区域的电脉冲直接反应发生的心脏去极化时，脉冲调节电路修改电脉冲的第一值。

46. 发明申请

US20120215294A1 CORONARY VEIN LEADS HAVING PRE-FORMED BIASED PORTIONS FOR FIXATION 有权
标题翻译：具有用于固定的预先形成的偏心部分的冠状动脉引导
公开(公告)号：US20120215294A1
公开(公告)日：2012-08-23
申请号：US13251466
申请日：2011-10-03
申请人： Avram Scheiner , Ronald W. Heil , Peter T. Kelley , Bruce Tockman , Randy Westlund , Jay A. Warren , Christina Repasky , Lyle A. Bye , Brian D. Soltis
发明人： Avram Scheiner , Ronald W. Heil , Peter T. Kelley , Bruce Tockman , Randy Westlund , Jay A. Warren , Christina Repasky , Lyle A. Bye , Brian D. Soltis
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead having a pre-formed biased portion is adapted for implantation with a body vessel and for connection to a signal generator. The lead is constructed and arranged so that when it is implanted, the electrodes are biased toward a vessel wall by the preformed biased portion, which operates to fixate the lead against the vessel wall.
摘要翻译：具有预成形的偏置部分的引线适于用身体容器注入并连接到信号发生器。引线被构造和布置成使得当其被植入时，电极通过预先形成的偏压部分朝向血管壁偏压，该部分操作以将引线固定在血管壁上。

47. 发明授权

US09572982B2 Techniques for placing medical leads for electrical stimulation of nerve tissue 有权
标题翻译：放置用于电刺激神经组织的医疗线的技术
公开(公告)号：US09572982B2
公开(公告)日：2017-02-21
申请号：US12433766
申请日：2009-04-30
申请人： John E. Burnes , Kenneth C. Gardeski , Ruth N. Klepfer , Patrick E. Macaulay , Mary M. Morris , Avram Scheiner
发明人： John E. Burnes , Kenneth C. Gardeski , Ruth N. Klepfer , Patrick E. Macaulay , Mary M. Morris , Avram Scheiner
IPC分类号： A61B19/00 , A61N1/36 , A61N1/05 , A61M25/09
CPC分类号： A61N1/36053 , A61M25/09 , A61N1/05 , A61N1/0551 , A61N1/0558 , A61N1/057 , A61N1/36085 , A61N1/36114 , A61N1/36125 , A61N1/36128
摘要： This disclosure is directed to extra, intra, and transvascular medical lead placement techniques for arranging medical leads and electrical stimulation and/or sensing electrodes proximate nerve tissue within a patient.
摘要翻译：本公开涉及用于在患者体内靠近神经组织布置医疗引线和电刺激和/或感测电极的额外的，内部的和经血管内的医疗引线放置技术。

48. 发明授权

US09026206B2 Therapy system including cardiac rhythm therapy and neurostimulation capabilities 有权
标题翻译：治疗系统包括心律治疗和神经刺激能力
公开(公告)号：US09026206B2
公开(公告)日：2015-05-05
申请号：US12610160
申请日：2009-10-30
申请人： Paul G. Krause , Avram Scheiner
发明人： Paul G. Krause , Avram Scheiner
IPC分类号： A61N1/362 , A61N1/36 , A61N1/365
CPC分类号： A61N1/36114 , A61N1/36514 , A61N1/36521
摘要： An implantable medical system that includes a cardiac therapy module and a neurostimulation therapy module may identify when neurostimulation electrodes have migrated toward a patient's heart. In some examples, the system may determine whether the neurostimulation electrodes have migrated toward the patient's heart based on a physiological response to an electrical signal delivered to the patient via the neurostimulation electrodes. In addition, in some examples, the system may determine whether the neurostimulation electrodes have migrated toward the patient's heart based on an electrical cardiac signal sensed via the neurostimulation electrodes.
摘要翻译：包括心脏治疗模块和神经刺激治疗模块的可植入医疗系统可以识别神经刺激电极何时向患者的心脏移动。在一些示例中，系统可以基于对通过神经刺激电极递送给患者的电信号的生理反应来确定神经刺激电极是否已经向患者的心脏迁移。此外，在一些示例中，系统可以基于经由神经刺激电极感测的电心脏信号来确定神经刺激电极是否已经向患者的心脏迁移。

49. 发明授权

US08660638B2 Syncope logbook and method of using same 有权
标题翻译：晕厥日志及其使用方法
公开(公告)号：US08660638B2
公开(公告)日：2014-02-25
申请号：US12616536
申请日：2009-11-11
申请人： Jeffrey E. Stahmann , John D. Hatlestad , Jesse W. Hartley , Avram Scheiner
发明人： Jeffrey E. Stahmann , John D. Hatlestad , Jesse W. Hartley , Avram Scheiner
IPC分类号： A61B5/0402
CPC分类号： A61B5/02028 , A61B5/0031 , A61B5/0205 , A61B5/0215 , A61B5/02405 , A61B5/0402 , A61B5/0476 , A61B5/11 , A61B5/1116 , A61B5/145 , A61B5/14532 , A61B5/14546 , A61N1/362 , A61N1/37247 , G06F19/00 , G06F19/3418 , G06F19/3481 , G16H40/63
摘要： Methods and systems are directed to acquiring and organizing information associated with at least one syncope event. A syncope event may be a suspected syncope event, a verified syncope event or a syncope event that is suspected and verified. Automated processes are used to collect information associated with at least one syncope event and organize the information as a syncope log entry. At least one of acquiring the information and organizing the information is performed at least in part implantably.
摘要翻译：方法和系统旨在获取和组织与至少一个晕厥事件相关联的信息。晕厥事件可能是疑似晕厥事件，经过验证的晕厥事件或怀疑和验证的晕厥事件。自动进程用于收集与至少一个晕厥事件相关的信息，并将该信息组织为晕厥日志条目。至少部分地可植入地执行获取信息和组织信息中的至少一个。

50. 发明授权

US08634921B2 Implantable and rechargeable neural stimulator 有权
标题翻译：可植入和可充电的神经刺激器
公开(公告)号：US08634921B2
公开(公告)日：2014-01-21
申请号：US13402196
申请日：2012-02-22
申请人： Abhi V. Chavan , Anthony V. Caparso , Avram Scheiner
发明人： Abhi V. Chavan , Anthony V. Caparso , Avram Scheiner
IPC分类号： A61N1/05
CPC分类号： A61N1/36117 , A61N1/3605 , A61N1/36071 , A61N1/36135 , A61N1/37205 , A61N1/37217 , A61N1/37288 , A61N1/3787
摘要： One aspect of the present subject matter relates to an implantable medical device. An embodiment of the device comprises a rechargeable power supply adapted to be recharged through an ultrasound signal, a neural stimulator connected to the rechargeable power supply, and a controller connected to the rechargeable power supply. The neural stimulator is adapted to generate a neural stimulation signal for delivery to a neural stimulation target through an electrode. The controller is further connected to the neural stimulator to control the neural stimulator according to a neural stimulation protocol. Other aspects are provided herein.
摘要翻译：本主题的一个方面涉及可植入医疗装置。该装置的实施例包括适于通过超声信号再充电的可再充电电源，连接到可再充电电源的神经刺激器和连接到可再充电电源的控制器。神经刺激器适于产生用于通过电极递送到神经刺激靶的神经刺激信号。控制器进一步连接到神经刺激器，以根据神经刺激方案来控制神经刺激器。本文提供了其他方面。

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