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    • 10. 发明授权
    • Method and system for rapid non-invasive determination of the systolic
time intervals
    • 方法和系统用于快速无创确定收缩时间间隔
    • US4094308A
    • 1978-06-13
    • US715895
    • 1976-08-19
    • Denny Charles Cormier
    • Denny Charles Cormier
    • A61B5/0245A61B5/024A61B5/025G06F17/00A61N5/02
    • A61B5/024
    • A non-invasive method and means for determining beat-by-beat assessments of a patient's cardiac performance by measuring the "pre-ejection phase" (PEP) and the "left ventricular ejection time" (LVET), the aforementioned phrases also being known as the "systolic time intervals" (STI) of the heart. The system accomplishes its function through the following method: (1) transduction of the heart sounds into an electrical phonocardiogram (PCG) signal and controlled amplification thereof; (2) extraction of initial cardiac contraction and aortic valvular events by subjecting the PCG to the general inverse-filtering technique known as "deconvolution;" (3) electronic separation of the PEP, LVET and heart pulse intervals from the deconvolved PCG with microcomputer circuitry comprising microprocessor and digital logic assemblies; (4) precise measurement and simultaneous storage of the PEP, LVET, the PEP/LVET ratio, and the heart rate with the use of electronic digital counters, timers, dividers, and buffer memories after every heart beat; and (5) finally effecting digital readout for instantly displaying the systolic time intervals, their respective ratio, and the heart rate, or for storing them for later use.
    • 通过测量“预喷射阶段”(PEP)和“左心室射血时间”(LVET)来确定患者心脏性能的逐搏评估的非侵入性方法和装置,上述短语也是已知的 作为心脏的“收缩时间间隔”(STI)。 该系统通过以下方法实现其功能:(1)将心音转换为电声心电图(PCG)信号及其控制放大; (2)通过对PCG进行称为“去卷积”的一般逆滤波技术,提取初始心脏收缩和主动脉瓣瓣事件。 (3)由包括微处理器和数字逻辑组件的微机电路与解卷积PCG电隔离PEP,LVET和心脏脉搏间隔; (4)每次心跳后使用电子数字计数器,定时器,分频器和缓冲存储器精确测量和同时存储PEP,LVET,PEP / LVET比和心率; 和(5)最终实现数字读出以立即显示收缩时间间隔,它们各自的比例和心率,或用于存储它们供以后使用。