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41. 发明申请

US20110198843A1 PORT STRUCTURE AND FLUID DEVICE INCLUDING THE PORT STRUCTURE 审中-公开
标题翻译：港口结构和流体装置，包括港口结构
公开(公告)号：US20110198843A1
公开(公告)日：2011-08-18
申请号：US13007138
申请日：2011-01-14
申请人： Shinji IKENOYA , Kiyoshi NAGAI
发明人： Shinji IKENOYA , Kiyoshi NAGAI
IPC分类号： F16L19/00
CPC分类号： F16L47/04 , F16L19/065 , F16L19/07
摘要： A port structure for connecting a resin tube to a port part includes a tube insertion hole in which the tube is inserted, a female screw portion provided in an opening of the tube insertion hole, and a tapered hole provided on a inward side of the female screw portion and formed with a taper with a diameter decreasing from the female screw side to the rear end. When a nut is screwed into the female screw portion to press the ferrule against the tapered hole, a repulsive force of the tapered hole acts on a tapered surface of the ferrule, elastically deforming the ferrule radially inward so that the ferrule bites into the tube and is pressed against the tapered hole to provide a seal.
摘要翻译：用于将树脂管连接到端口部分的端口结构包括插入管的管插入孔，设置在管插入孔的开口中的阴螺纹部分和设在母体内侧的锥形孔螺纹部分形成有直径从内螺纹侧到后端的锥度。当螺母拧入内螺纹部分以将套圈压靠锥形孔时，锥形孔的排斥力作用在套圈的锥形表面上，径向向内使套圈弹性变形，使得套圈咬入管中，被压靠在锥形孔上以提供密封。

42. 发明授权

US06514776B1 Instrument and method for measuring contamination of wafer surface 有权
标题翻译：用于测量晶片表面污染的仪器和方法
公开(公告)号：US06514776B1
公开(公告)日：2003-02-04
申请号：US09599205
申请日：2000-06-22
申请人： Kumiko Yanagi , Harumi Shibata , Kiyoshi Nagai
发明人： Kumiko Yanagi , Harumi Shibata , Kiyoshi Nagai
IPC分类号： H01L2166
CPC分类号： H01L21/68721 , H01L21/67028 , H01L21/67069 , H01L21/6835 , H01L21/68764 , H01L21/68785
摘要： There is described an instrument capable of immediately and accurately extracting contaminants from solely either side of a wafer surface or from a certain area on the wafer surface. O-rings, each of which is partially cut, are attached to respective sides of wafer holding members. A wafer is held from respective sides by the wafer holding members. Extraction of contaminants from the upper surface of the wafer is carried out independently of extraction of contaminants from the underside of the wafer, by means of feeding extraction solvent to the interior spaces defined by the respective O-rings. Thereby, quick and appropriate extraction of contaminants from either side of a wafer.
摘要翻译：描述了能够从晶片表面的任一侧或晶片表面上的特定区域立即且准确地提取污染物的仪器。每一个被部分切割的O形环连接到晶片保持构件的相应侧。晶片由晶片保持构件从相应的侧面保持。通过将提取溶剂供给到由各个O形环限定的内部空间，从晶片的上表面提取污染物是独立于从晶片的下侧提取污染物而进行的。因此，从晶片的任一侧快速和适当地提取污染物。

43. 发明授权

US5962476A Azolylamine derivative 失效
标题翻译：唑基胺衍生物
公开(公告)号：US5962476A
公开(公告)日：1999-10-05
申请号：US966527
申请日：1997-11-10
申请人： Takanobu Naito , Haruhito Kobayashi , Hironobu Ogura , Kiyoshi Nagai , Tokiko Nishida , Tadashi Arika , Mamoru Yokoo , Satoko Shusse
发明人： Takanobu Naito , Haruhito Kobayashi , Hironobu Ogura , Kiyoshi Nagai , Tokiko Nishida , Tadashi Arika , Mamoru Yokoo , Satoko Shusse
IPC分类号： C07D521/00 , A61K31/445 , C07D401/06
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08
摘要： There is disclosed a fungicide containing, as an effective ingredient, a compound having the general formula (I): ##STR1## or an acid addition salt thereof, particularly the compound wherein an absolute configuration of the asymmetric carbon atoms is R,R-configuration or an acid addition salt thereof.
摘要翻译：公开了含有具有通式（I）的化合物或其酸加成盐作为有效成分的杀真菌剂，特别是不对称碳原子的绝对构型为R，R构型或酸的化合物加成盐。

44. 发明授权

US5844089A Genetically fused globin-like polypeptides having hemoglobin-like activity 失效
标题翻译：具有血红蛋白样活性的遗传融合的球蛋白样多肽
公开(公告)号：US5844089A
公开(公告)日：1998-12-01
申请号：US450733
申请日：1995-05-25
申请人： Stephen J. Hoffman , Douglas L. Looker , Mary S. Rosendahl , Gary L. Stetler , Michael Wagenbach , David C. Anderson , Antony James Mathews , Kiyoshi Nagai
发明人： Stephen J. Hoffman , Douglas L. Looker , Mary S. Rosendahl , Gary L. Stetler , Michael Wagenbach , David C. Anderson , Antony James Mathews , Kiyoshi Nagai
IPC分类号： A61K38/16 , A61K38/00 , A61K47/48 , A61P7/08 , C07K20060101 , C07K1/113 , C07K14/805 , C12N15/00 , C12N15/09 , C12N15/12 , C12N15/81 , C12P21/02 , C12R1/19 , C12R1/91
CPC分类号： C07K14/805 , A61K47/48307 , C12N15/81 , A61K38/00 , C07K2319/00 , C07K2319/50 , C07K2319/92
摘要： The alpha subunits of hemoglobin, which in nature are formed as separate polypeptide chains which bind noncovalently to the beta subunits, are here provided in the form of the novel molecule di-alpha globin, a single polypeptide chain defined by connecting the two alpha subunits either directly via peptide bond or indirectly by a flexible amino acid or peptide linker. Di-alpha globin may be combined in vivo or in vitro with beta globin and heme to form hemoglobin. Di-alpha globin is expressed by recombinant DNA techniques. Di-beta globin may be similarly obtained.
摘要翻译：在本文中，血红蛋白的α亚基本质上被形成为与β-亚基非共价结合的分离的多肽链，这里以新分子二-α球蛋白的形式提供，单链多肽链通过将两个α亚基连接而定义直接通过肽键或通过柔性氨基酸或肽接头间接。 Di-α珠蛋白可以在体内或体外与β球蛋白和血红素组合以形成血红蛋白。 Di-α球蛋白通过重组DNA技术表达。可以类似地获得二β-珠蛋白。

45. 发明授权

US5661124A Blood substitutes 失效
标题翻译：血液替代品
公开(公告)号：US5661124A
公开(公告)日：1997-08-26
申请号：US396866
申请日：1995-03-01
申请人： Stephen J. Hoffman , Kiyoshi Nagai
发明人： Stephen J. Hoffman , Kiyoshi Nagai
IPC分类号： A61K38/00 , C07K14/805 , A61K38/16 , C07K14/00
CPC分类号： C07K14/805 , A61K38/00 , C07K2319/00 , Y10S514/832 , Y10S514/833
摘要： The present invention provides blood substitutes comprised of recombinantly produced mutant hemoglobin having an osmolarity greater than 303 milliosmoles per liter and less than 800 milliosmoles per liter. Such hyperosmolar blood substitute additionally comprises a physiologically acceptable molecule less diffusible than dextrose.
摘要翻译：本发明提供血液替代物，其包含重组产生的突变体血红蛋白，其渗透压大于303毫摩尔每升且小于800毫摩尔每升。这种高渗血液替代品另外包含比葡萄糖更不易扩散的生理上可接受的分子。

46. 发明授权

US5563254A Polynucleotides encoding genetically engineered mutant hemoglobins 失效
标题翻译：编码基因工程突变体血红蛋白的多核苷酸
公开(公告)号：US5563254A
公开(公告)日：1996-10-08
申请号：US170095
申请日：1993-12-20
申请人： Stephen J. Hoffman , Kiyoshi Nagai
发明人： Stephen J. Hoffman , Kiyoshi Nagai
IPC分类号： A61K38/00 , C07K14/805 , C07H17/00 , C07K14/085 , C12P9/00 , C12P21/06
CPC分类号： C07K14/805 , A61K38/00 , C07K2319/00 , Y10S514/832 , Y10S514/833
摘要： The present invention provides for polynucleotides capable of producing recombinant hemoglobins that have a P.sub.50 of 26-36 torr. This invention makes possible the commercial production of wholly artificial hemoglobin, whether conventional or mutant in form, which can be used as blood substitutes.
摘要翻译：本发明提供能够产生P50为26-36托的重组血红蛋白的多核苷酸。本发明使得可以商业生产完全人造血红蛋白，无论是常规的还是突变的形式，其可以用作血液代用品。

47. 发明授权

US5449759A Hemoglobins with intersubunit desulfide bonds 失效
标题翻译：血红蛋白与亚基间脱硫键
公开(公告)号：US5449759A
公开(公告)日：1995-09-12
申请号：US158483
申请日：1993-11-29
申请人： Stephen J. Hoffman , Kiyoshi Nagai
发明人： Stephen J. Hoffman , Kiyoshi Nagai
IPC分类号： A61K38/00 , C07K14/805 , A61K38/42
CPC分类号： C07K14/805 , A61K38/00 , C07K2319/00 , Y10S514/832 , Y10S514/833
摘要： Cysteine substitution mutants of alpha and/or beta globin mutants are produced by recombinant DNA techniques and used in the construction, intracellularly or otherwise, of mutant hemoglobins in which alpha- and beta-globin like subunits are crosslinked by disulfide bonds. Solutions of these mutant hemoglobins are used as blood substitutes.Preferably, these mutant hemoglobins contain further mutations which reduce their affinity for oxygen.Hemoglobins are preferably obtained by recombinant DNA techniques. Both alpha and beta globin chains can now be readily expressed, making possible the commercial production of wholly artificial hemoglobin, whether conventional or mutant in form. Solutions of wholly artificial hemoglobins are also used as blood substitutes. Expression of the alpha globin gene was substantially improved by means of a beta globin gene "header".
摘要翻译： α和/或β球蛋白突变体的半胱氨酸取代突变体通过重组DNA技术产生并用于构建，细胞内或其它突变体血红蛋白，其中α和β-珠蛋白样亚基通过二硫键交联。这些突变体血红蛋白的溶液用作血液代用品。优选地，这些突变体血红蛋白含有进一步降低其对氧的亲和力的突变。血红蛋白优选通过重组DNA技术获得。现在可以容易地表达α和β球蛋白链，使得完全人造血红蛋白的商业生产成为可能，无论是常规的还是突变形式。完全人造血红蛋白的溶液也用作血液代用品。通过β球蛋白基因“头”，α球蛋白基因的表达显着改善。

48. 发明授权

US5084806A Light emitting display device and stem for light emitting display device 失效
标题翻译：用于发光显示装置的发光显示装置和灯杆
公开(公告)号：US5084806A
公开(公告)日：1992-01-28
申请号：US599630
申请日：1990-10-18
申请人： Kiyoshi Nagai
发明人： Kiyoshi Nagai
IPC分类号： G09F13/28 , F21S8/00 , H01K7/04 , H01K9/00
CPC分类号： H01K9/00 , H01K7/04 , F21W2111/00
摘要： Disclosed is a light emitting display device comprising: a stem member comprising a lidless container having a plural number of chambers divided by partially chipped walls, filaments and their support posts arranged in each chamber; and a lid panel having transparent windows and light-shielding face. The lid panel is airtightly fixed on the upper side of the container so that the light-shielding face covers the upper portions of the chipped parts of the walls. The inside of the device is made vacuum.
摘要翻译：本发明公开了一种发光显示装置，其特征在于，包括：杆构件，其包括无孔容器，所述无盖容器具有多个室，所述多个室由部分切开的壁分隔开;灯丝及其支撑柱布置在每个室中; 以及具有透明窗口和遮光面的盖板。盖板被气密地固定在容器的上侧，使得遮光面覆盖壁的切屑部分的上部。设备的内部是真空的。

49. 发明授权

US5055420A Process for fabricating semiconductor integrated circuit devices 失效
标题翻译：制造半导体集成电路器件的工艺
公开(公告)号：US5055420A
公开(公告)日：1991-10-08
申请号：US351323
申请日：1989-05-09
申请人： Shuji Ikeda , Kouichi Nagasawa , Makoto Motoyoshi , Kiyoshi Nagai , Satoshi Meguro
发明人： Shuji Ikeda , Kouichi Nagasawa , Makoto Motoyoshi , Kiyoshi Nagai , Satoshi Meguro
IPC分类号： H01L21/8238 , H01L27/092 , H01L29/08
CPC分类号： H01L21/823814 , H01L29/0847 , H01L27/0928
摘要： After contact holes for the P- and N-type source or drain regions of P- and N-channel MOSFETs have been made at a common step, an N-type impurity is ion-implanted into at least the N-type source or drain regions through the contact holes. The N-type impurity is annealed to fornm an N-type region which is deeper than the N-type source or drain regions. During the annealing treatment, the N-type source or drain regions are covered with an insulating film.

50. 发明授权

US4448809A Method of silver plating stainless steel vacuum bottle surfaces 失效
标题翻译：镀银方法不锈钢真空瓶表面
公开(公告)号：US4448809A
公开(公告)日：1984-05-15
申请号：US429890
申请日：1982-09-30
申请人： Kiyoshi Nagai , Hiroshi Shinohara , Nobuo Imamura
发明人： Kiyoshi Nagai , Hiroshi Shinohara , Nobuo Imamura
IPC分类号： C23C18/18 , B05D7/22 , B05D7/14 , C23C3/02
CPC分类号： C23C18/1817 , C23C18/42
摘要： A method of silver plating stainless steel vacuum bottle surfaces includes the steps of thermally treating the surfaces to be coated at a temperature of at least 200.degree. C. and then using an electroless plating technique to silver plate the thermally treated surfaces. The thermal treatment can be as low as 200.degree. C. if it occurs in an atmosphere of at least 5% hydrogen gas. If the thermal treatment occurs in a vacuum, however, the temperature must be at least 700.degree. C.
摘要翻译：镀银不锈钢真空瓶表面的方法包括以下步骤：在至少200℃的温度下对待涂覆的表面进行热处理，然后使用化学镀技术将热处理表面镀银。如果发生在氢气至少5％的气氛中，则热处理可以低至200℃。然而，如果热处理发生在真空中，则温度必须至少为700℃

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