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31. 发明申请

US20020045889A1 Systems and methods for corneal surface ablation to correct hyperopia 有权
标题翻译：角膜表面消融矫正远视的系统和方法
公开(公告)号：US20020045889A1
公开(公告)日：2002-04-18
申请号：US09950563
申请日：2001-09-10
发明人： Richard A. Hofer , Stephen J. Koons , John Karl Shimmick
IPC分类号： A61B018/20
CPC分类号： A61F9/008 , A61F9/00804 , A61F9/00817 , A61F2009/00844 , A61F2009/00872 , A61F2009/00882
摘要： Systems, methods and apparatus for performing selective ablation of a corneal surface of an eye to effect a desired corneal shape, particularly for correcting a hyperopic/astigmatic condition by laser sculpting the corneal surface to increase its curvature. In one aspect of the invention, a method includes the steps of directing a laser beam onto a corneal surface of an eye, and changing the corneal surface from an initial curvature having hyperopic and astigmatic optical properties to a subsequent curvature having correctively improved optical properties. Thus, the curvature of the anterior corneal surface is increased to correct hyperopia, while cylindrical volumetric sculpting of the corneal tissue is performed to correct the astigmatism. The hyperopic and astigmatic corrections are preferably performed by establishing an optical correction zone on the anterior corneal surface of the eye, and directing a laser beam through a variable aperture element designed to produce a rectangular ablation (i.e., cylindrical correction) on a portion of the optical correction zone. The laser beam is then displaced by selected amounts across the optical correction zone to produce a series of rectangular ablations on the correction zone that increases the curvature of the corneal surface to correct the hyperopic refractive error.
摘要翻译：用于进行眼睛的角膜表面的选择性消融以实现期望的角膜形状的系统，方法和装置，特别是通过激光雕刻角膜表面以增加其曲率来校正远视/散光状态。在本发明的一个方面，一种方法包括以下步骤：将激光束引导到眼睛的角膜表面上，并且将角膜表面从具有远视和散光光学特性的初始曲率改变为具有校正改善的光学性质的后续曲率。因此，前角膜表面的曲率增加以校正远视，而进行角膜组织的圆柱体积雕刻以校正散光。优选通过在眼睛的前角膜表面上建立光学校正区域来引导远视和散光校正，并且将激光束引导通过可变孔径元件，所述可变孔径元件被设计成在所述眼部的一部分上产生矩形消融（即圆柱形校正）光学校正区。然后，激光束通过光学校正区域移动选定的量，以在校正区域上产生一系列矩形消融，增加角膜表面的曲率以校正远视屈光不正。

32. 发明申请

US20020016586A1 Method and system for laser treatment of refractive errors using offset imaging 审中-公开
$Method and system for laser treatment of refractive errors using offset imaging$
标题翻译：使用偏移成像激光治疗屈光不正的方法和系统
公开(公告)号：US20020016586A1
公开(公告)日：2002-02-07
申请号：US09923863
申请日：2001-08-06
发明人： John K. Shimmick , William B. Telfair , Charles R. Munnerlyn , Herrmann J. Glockler
IPC分类号： A61F009/008
CPC分类号： A61F9/008 , A61F9/00804 , A61F9/00806 , A61F9/00817 , A61F2009/00844 , A61F2009/00872 , A61F2009/00882
摘要： An ophthalmological surgery system and method for performing ablative photodecomposition of the corneal surface by offset image scanning. The image of a variable aperture, such as a variable width slit and variable diameter iris diaphragm, is scanned in a preselected pattern to perform ablative sculpting of predetermined portions of a corneal surface. The scanning is performed with a movable image offset displacement mechanism capable of effecting radial displacement and angular rotation of the profiled beam exiting from the variable aperture. The profiled beam is rotated by rotating the aperture in conjunction with the offset displacement mechanism. The invention enables wide area treatment with a laser having a narrower beam, and can be used in the treatment of many different conditions, such as hyperopia, hyperopic astigmatism, irregular refractive aberrations, post ablation smoothing and phototherapeutic keratectomy.
摘要翻译：一种用于通过偏移图像扫描进行角膜表面的烧蚀性光分解的眼科手术系统和方法。可变孔径的图像，例如可变宽度狭缝和可变直径虹膜光阑，以预选图案扫描，以进行角膜表面的预定部分的烧蚀雕刻。利用可移动图像偏移位移机构进行扫描，该移动图像偏移位移机构能够实现从可变孔径出射的成像光束的径向位移和角度旋转。通过与偏移位移机构一起旋转孔而使成型梁旋转。本发明能够利用具有较窄光束的激光进行广泛治疗，并且可以用于治疗远视，远视散光，不规则屈光像差，消融后平滑和光治疗角膜切除术等许多不同的条件。

33. 发明授权

US06312424B1 Method of vision correction 失效
公开(公告)号：US06312424B1
公开(公告)日：2001-11-06
申请号：US08506794
申请日：1995-07-25
申请人： James R. Largent
发明人： James R. Largent
IPC分类号： A61F901
CPC分类号： A61F9/008 , A61F9/00808 , A61F9/00817 , A61F2009/00872 , A61F2009/00895
摘要： A method of vision correction comprising shaping first and second regions of a cornea to provide the first region with a first vision correction power and the second region with a second vision correction power which is different from the first vision correction power to enhance vision at first and second distances, respectively.

34. 发明授权

US06302876B1 Systems and methods for imaging corneal profiles 失效
公开(公告)号：US06302876B1
公开(公告)日：2001-10-16
申请号：US09083773
申请日：1998-05-22
申请人： John K. Shimmick , Stephen J. Hinkson , Charles R. Munnerlyn
发明人： John K. Shimmick , Stephen J. Hinkson , Charles R. Munnerlyn
IPC分类号： A61F901
CPC分类号： A61F9/008 , A61F9/00804 , A61F9/00817 , A61F2009/00844 , A61F2009/00846 , A61F2009/00872 , A61F2009/00882
摘要： Systems, methods and apparatus for generating images of portions of the patient's eye, such as the anterior surface of the cornea. The methods and apparatus of the present invention are particularly useful for directly imaging the profile of the ablated region of the cornea during or immediately following a laser ablation procedure, such as photorefractive keratometry (PRK), phototherapeutic keratectomy (PTK), laser in-situ keratomileusis (LASIK) or the like. These methods and apparatus allow the surgeon to precisely image the exterior edge of the eye to characterize the profile of ablated corneas and to determine the spatial variance of tissue ablation rates during the surgical procedures. Methods and apparatus are also provided for generating one or more images depicting the profile of the ablated region of the cornea. The profile is registered with a pre-ablation profile to provide feedback regarding the true ablation properties of the eye. This feedback permits the laser system to be programmed with a laser ablation algorithm based on the measured ablation properties of the eye.

35. 发明授权

US06293939B1 Epithelium removal 有权
标题翻译：上皮去除
公开(公告)号：US06293939B1
公开(公告)日：2001-09-25
申请号：US09494993
申请日：2000-01-31
申请人： Roger F. Steinert
发明人： Roger F. Steinert
IPC分类号： A61B1818
CPC分类号： A61F9/008 , A61B2017/00061 , A61F9/00802 , A61F9/00804 , A61F9/00817 , A61F9/00819 , A61F2009/00872
摘要： Accurate, non-mechanical removal of the epithelium from essentially only the area of the cornea to be treated. In particular, an epithelium-ablative laser device irradiates the selected region of the epithelium with ablative laser energy, a spectroscopic system monitors the ablation and spectroscopically determines whether epithelium is being ablated, and a control system terminates the epithelium removal upon spectroscopic determination of a substantial absence of epithelium ablation.
摘要翻译：从基本上仅仅要治疗的角膜的区域精确地，非机械地去除上皮。特别地，消融激光设备用烧蚀激光能量照射所选择的上皮细胞区域，光谱系统监测消融并且光谱地确定上皮细胞是否被消融，并且控制系统在光谱测定实质上终止上皮细胞去除没有上皮细胞消融。

36. 发明授权

US6136012A Apparatus for operation on a cornea 失效
标题翻译：在角膜上操作的装置
公开(公告)号：US6136012A
公开(公告)日：2000-10-24
申请号：US121917
申请日：1998-07-24
申请人： Arturo S. Chayet , Yoshitaka Suzuki
发明人： Arturo S. Chayet , Yoshitaka Suzuki
IPC分类号： A61F9/01 , A61F9/00
CPC分类号： A61F9/008 , A61F9/00804 , A61F9/00817 , A61F2009/00872
摘要： An apparatus for operation on a cornea by ablating with a laser beam for correcting ametropia; the apparatus comprising an input device utilized for inputting each data necessary for correction, a first correcting device for irradiating a laser beam for correcting myopic astigmatism, a second correcting device for irradiating a laser beam for correcting hyperopic astigmatism, a calculating device for calculating each correction-data based on the each inputted data in case of combining the first and second correcting means, and a control device for ablating the cornea by controlling the first and second correcting means based on results calculated by the calculating device.
摘要翻译：一种用于通过用激光束烧蚀来矫正屈光不正的用于在角膜上操作的装置; 所述装置包括用于输入校正所需的每个数据的输入装置，用于照射用于校正近视散光的激光束的第一校正装置，用于照射用于校正远视像散的激光束的第二校正装置，用于计算每个校正的计算装置 - 基于在组合第一和第二校正装置的情况下的每个输入数据的数据，以及用于通过基于由计算装置计算的结果控制第一和第二校正装置来消融角膜的控制装置。

37. 发明授权

US6132421A Integrated epithelial removal tool 失效
标题翻译：综合上皮去除工具
公开(公告)号：US6132421A
公开(公告)日：2000-10-17
申请号：US86793
申请日：1998-05-28
申请人： Terrance N. Clapham
发明人： Terrance N. Clapham
IPC分类号： A61F9/008 , A61B18/18
CPC分类号： A61F9/00804 , A61F9/008 , A61F2009/00872 , A61F2009/00897 , A61F9/00817
摘要： The invention provides improved devices, systems, and methods for removing the epithelial layer of a patient's cornea, particularly in preparation for laser resculpting of the cornea. The invention makes use of an epithelial removal tool which is integrated into a laser eye surgery system. Structurally supporting the epithelial removal tool relative to the optical train allows precise control over the positioning of the tool relative to the cornea. The force and/or duration of epithelial abrasion can be controlled to avoid removal of excess corneal tissues, and the accurate alignment of the removal tool allows the total area of epithelium removal to be minimized while ensuring that adequate access is provided for resculpting. An orbital or concentric movement of the abrasion surface may provide a more even abrasion.
摘要翻译：本发明提供了用于去除患者角膜上皮层的改进的装置，系统和方法，特别是用于准备角膜的激光重塑。本发明利用整合到激光眼外科系统中的上皮移除工具。结构上支持相对于光学列车的上皮去除工具允许精确地控制工具相对于角膜的定位。可以控制上皮磨损的力和/或持续时间以避免去除多余的角膜组织，并且去除工具的精确对准允许最小化上皮细胞的总面积，同时确保为重塑提供足够的访问。磨损表面的轨道或同心运动可以提供更均匀的磨损。

38. 发明授权

US6056741A Dual beam laser ablation 失效
标题翻译：双光束激光烧蚀
公开(公告)号：US6056741A
公开(公告)日：2000-05-02
申请号：US894755
申请日：1997-10-21
申请人： Paul Phillip Van Saarloos
发明人： Paul Phillip Van Saarloos
IPC分类号： A61B18/20 , A61F9/01 , A61B17/36
CPC分类号： A61F9/008 , A61F9/00804 , A61B2018/207 , A61B2018/208 , A61F2009/00872 , A61F9/00817
摘要： A method for laser ablation of a tissue including directing at least one first pulsed laser beam of ultraviolet light and at least one second pulsed laser beam of infrared light to an area on the tissue to thereby ablate said tissue. The ultraviolet light has a wavelength of between 180 to 225 nm while the infrared light has a wavelength of between 1.4 to 11.0 .mu.m, and more specifically around 3.0 .mu.m. The tissue to be ablated may be the corneal tissue of the eye.
摘要翻译： PCT No.PCT / AU96 / 00108 Sec。 371日期1997年10月21日 102（e）日期1997年10月21日PCT 1996年3月1日PCT公布。公开号WO96 / 27335 日期1996年9月12日一种用于组织的激光烧蚀的方法，包括将至少一个紫外光的第一脉冲激光束和至少一个第二脉冲的红外光激光束引导到组织上的区域，从而烧蚀所述组织。紫外线的波长为180〜225nm，红外光的波长为1.4〜11.0μm，更具体为约3.0μm。要消融的组织可以是眼睛的角膜组织。

39. 发明授权

US6056739A Profiling the intensity distribution of optical beams 失效
标题翻译：分析光束的强度分布
公开(公告)号：US6056739A
公开(公告)日：2000-05-02
申请号：US748048
申请日：1996-11-12
申请人： Peter J. Klopotek
发明人： Peter J. Klopotek
IPC分类号： A61F9/008 , A61F9/01 , B23K26/067 , A61N5/06
CPC分类号： B23K26/0676 , A61F9/00804 , A61F9/00817 , B23K26/067 , A61F2009/00844 , A61F2009/00872 , A61F2009/00882
摘要： A beam profiler comprising: an intensity modifier constructed and arranged to separately modify the intensity profile of different subbeam portions of an initial beam to thereby create respective subbeams each having a respective predetermined modification; and a subbeam-directing optical system constructed and arranged to direct the multiple subbeams along respective subbeam beam paths that substantially overlap in an overlap plane, whereby, a resulting beam of radiation is created at the overlap plane that has an intensity profile equal to the optical incoherent summation of the predetermined intensity profiles of said overlapping subbeams. The intensity modifier preferably comprises an array of intensity-modifying profiling elements disposed across the initial beam each producing a corresponding subbeam.
摘要翻译：一种光束轮廓仪，包括：强度调节器，其被构造和布置成单独地修改初始光束的不同子光束部分的强度分布，从而产生各自具有相应的预定修改的子光束; 以及子束指向光学系统，其被构造和布置成沿着在重叠平面中基本重叠的相应子光束路径引导多个子光束，由此在具有等于光学器件的强度分布的重叠平面处产生所得到的辐射束所述重叠子光束的预定强度分布的非相干相加。强度调节剂优选地包括设置在初始光束两端的强度修改成像元件的阵列，每个产生相应的子光束。

40. 发明授权

US06004313A Patient fixation system and method for laser eye surgery 失效
标题翻译：激光眼科手术患者固定系统及方法
公开(公告)号：US06004313A
公开(公告)日：1999-12-21
申请号：US105690
申请日：1998-06-26
申请人： John K. Shimmick , Vladimir Lemberg , Terrance N. Clapham , Charles R. Munnerlyn
发明人： John K. Shimmick , Vladimir Lemberg , Terrance N. Clapham , Charles R. Munnerlyn
IPC分类号： A61B18/20 , A61F9/007 , A61F9/008 , A61F9/01 , A61B17/36
CPC分类号： A61F9/008 , A61F9/00804 , A61F9/00817 , A61F2009/00844 , A61F2009/00872 , A61F2009/00882
摘要： Enhancement of the alignment between the eye and a laser beam of a laser eye surgery system using a visual fixation system, the fixation system often having an adjustable optical train. The optical train of the fixation system allows an eye having a significant refractive error to be accurately focused at a fixation target. To accommodate the refractive error, the adjustable optical train will often project an image of the target so that the projected image is in focus in front of or behind the plane of the patient's eye.
摘要翻译：使用视觉固定系统增强眼睛和激光眼睛手术系统的激光束之间的对准，该固定系统通常具有可调整的光学列车。固定系统的光学系统允许具有显着的折射误差的眼睛准确地聚焦在固定目标上。为了适应折射误差，可调节的光学列车将经常投射目标的图像，使得投影图像在患者眼睛的平面前方或后方聚焦。

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