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1. 发明授权

US08496696B2 System and method for microablation of tissue 有权
公开(公告)号：US08496696B2
公开(公告)日：2013-07-30
申请号：US11730017
申请日：2007-03-29
申请人： Vladimir Lemberg , Vitali Epshtein , Yoni Iger , John Lee Pannell
发明人： Vladimir Lemberg , Vitali Epshtein , Yoni Iger , John Lee Pannell
IPC分类号： A61N5/06
CPC分类号： A61B18/203 , A61B2017/00761 , A61B2017/00765 , A61B2018/00452 , A61B2018/00458
摘要： The present invention generally relates to the field of laser treatment of tissue, and particularly, to a system and method for creating microablated channels in skin. The present invention is more particularly directed to treating subsurface tissue through the created channels.

2. 发明申请

US20120083777A1 SYSTEM AND METHOD FOR MICROABLATION OF TISSUE 审中-公开
标题翻译：用于组织微阵列的系统和方法
公开(公告)号：US20120083777A1
公开(公告)日：2012-04-05
申请号：US13314548
申请日：2011-12-08
申请人： VLADIMIR LEMBERG , VITALI EPSHTEIN , YONI IGER , JOHN LEE PANNELL
发明人： VLADIMIR LEMBERG , VITALI EPSHTEIN , YONI IGER , JOHN LEE PANNELL
IPC分类号： A61B18/20
CPC分类号： A61B18/203 , A61B2017/00761 , A61B2017/00765 , A61B2018/00452 , A61B2018/00458
摘要： The present invention generally relates to the field of laser treatment of tissue, and particularly, to a system and method for creating microablated channels in skin. The present invention is more particularly directed to treating subsurface tissue through the created channels.
摘要翻译：本发明一般涉及组织的激光治疗领域，特别涉及用于在皮肤中产生微细通道的系统和方法。本发明更具体地涉及通过所产生的通道处理地下组织。

3. 发明申请

US20110077627A1 System and method for Microablation of tissue 有权
标题翻译：组织微消融的系统和方法
公开(公告)号：US20110077627A1
公开(公告)日：2011-03-31
申请号：US12799064
申请日：2010-04-15
申请人： Vladimir Lemberg , Ray Choye
发明人： Vladimir Lemberg , Ray Choye
IPC分类号： A61B18/20 , A61N5/067
CPC分类号： A61B18/203 , A61B2017/00057 , A61B2018/00452 , A61B2018/00458 , A61B2018/00577 , A61B2018/00642 , A61B2018/00994
摘要： The present invention generally relates to the field of laser treatment of tissue, and particularly, to a system and method for creating microablated channels in skin. The present invention is more particularly directed to treating subsurface tissue through the created channels.
摘要翻译：本发明一般涉及组织的激光治疗领域，特别涉及用于在皮肤中产生微细通道的系统和方法。本发明更具体地涉及通过所产生的通道处理地下组织。

4. 发明授权

US06491686B2 Method and system for scanning non-overlapping patterns of laser energy with diffractive optics 有权
$Method and system for scanning non-overlapping patterns of laser energy with diffractive optics$
标题翻译：用衍射光学器件扫描不重叠的激光能量图案的方法和系统
公开(公告)号：US06491686B2
公开(公告)日：2002-12-10
申请号：US09537201
申请日：2000-03-28
申请人： Vladimir Lemberg
发明人： Vladimir Lemberg
IPC分类号： A61B1818
CPC分类号： A61F9/008 , A61F9/00804 , A61F9/00817 , A61F2009/00844 , A61F2009/00872
摘要： A system for laser treatment of the eye comprises one or more diffractive optical elements for producing unique treatment segments within an ablation zone on the eye. The treatment segments may be annular, pie-shaped, or have other geometries or patterns selected to apply energy in a particular manner, usually in a non-overlapping manner so that energy dosages can be precisely controlled. In a first embodiment of the system, a single diffractive optical element is used and a beam expander expands or converges the beam to achieve the different treatment segments. In a second embodiment, a plurality of diffractive optical elements are used, each of which produces a single treatment segment.
摘要翻译：用于激光治疗眼睛的系统包括一个或多个衍射光学元件，用于在眼睛的消融区域内产生独特的治疗段。处理段可以是环形的，饼形的，或者具有其它几何形状或图案，以特定方式施加能量，通常以非重叠的方式施加能量，从而能够精确地控制能量剂量。在系统的第一实施例中，使用单个衍射光学元件，并且光束扩展器使光束扩展或收敛以实现不同的处理段。在第二实施例中，使用多个衍射光学元件，每个衍射光学元件产生单个处理段。

5. 发明授权

US06406473B1 Patient fixation system and method for laser eye surgery 有权
标题翻译：激光眼科手术患者固定系统及方法
公开(公告)号：US06406473B1
公开(公告)日：2002-06-18
申请号：US09411785
申请日：1999-10-01
申请人： John K. Shimmick , Vladimir Lemberg , Terrance N. Clapham , Charles R. Munnerlyn
发明人： John K. Shimmick , Vladimir Lemberg , Terrance N. Clapham , Charles R. Munnerlyn
IPC分类号： A61B1818
CPC分类号： A61F9/008 , A61B3/152 , A61F9/00804 , A61F2009/00846 , A61F2009/00872
摘要： A visual fixation system which enhances the alignment between the eye and a laser beam of a laser eye surgery system, the fixation system often having an adjustable optical train. The optical train of the fixation system allows an eye having a significant refractive error to be accurately focused at a fixation target. To accommodate the refractive error, the adjustable optical train will often project an image of the target so that the projected image is in focus in front of or behind the plane of the patient's eye. The proper projection distance is calculated to accommodate the refractive error of the eye, the calculation preferably based at least in-part on the eye glass prescription for that eye.
摘要翻译：一种视觉固定系统，其增强了眼睛与激光眼睛手术系统的激光束之间的对准，该固定系统通常具有可调整的光学列车。固定系统的光学系统允许具有显着的折射误差的眼睛准确地聚焦在固定目标上。为了适应折射误差，可调节的光学列车将经常投射目标的图像，使得投影图像在患者眼睛的平面前方或后方聚焦。计算适当的投影距离以适应眼睛的屈光不正，该计算优选至少部分地基于该眼睛的眼玻璃处方。

6. 发明授权

US06793654B2 Optical feedback system for vision correction 有权
标题翻译：光学反馈系统用于视力矫正
公开(公告)号：US06793654B2
公开(公告)日：2004-09-21
申请号：US10160211
申请日：2002-05-28
申请人： Vladimir Lemberg
发明人： Vladimir Lemberg
IPC分类号： A61B1818
CPC分类号： A61B3/12 , A61B3/103 , A61B2017/00022 , A61F9/00804 , A61F2009/00844 , A61F2009/00848 , A61F2009/00872
摘要： The invention provides laser eye surgery devices, systems, and methods which measure the refractive error in the eye before, during, and/or after vision correction surgery. The invention allows adjustments during the vision correction operation, and allows qualitative and/or quantitative measurements of the progress of photorefractive treatments by projecting and imaging reference images though the cornea and other components of the ocular optical system. A slope of an image quality value such as an Optical Transfer Function may be monitored during the procedure to help determine when to terminate treatment.
摘要翻译：本发明提供了在视力矫正手术之前，期间和/或之后测量眼睛中的屈光不正的激光眼手术装置，系统和方法。本发明允许在视力矫正操作期间进行调节，并允许通过投影和成像通过眼睛光学系统的角膜和其它部件的参考图像来定性和/或定量地测量光折射治疗的进展。可以在该过程期间监视诸如光学传递函数的图像质量值的斜率，以帮助确定何时终止治疗。

7. 发明授权

US06004313A Patient fixation system and method for laser eye surgery 失效
标题翻译：激光眼科手术患者固定系统及方法
公开(公告)号：US06004313A
公开(公告)日：1999-12-21
申请号：US105690
申请日：1998-06-26
申请人： John K. Shimmick , Vladimir Lemberg , Terrance N. Clapham , Charles R. Munnerlyn
发明人： John K. Shimmick , Vladimir Lemberg , Terrance N. Clapham , Charles R. Munnerlyn
IPC分类号： A61B18/20 , A61F9/007 , A61F9/008 , A61F9/01 , A61B17/36
CPC分类号： A61F9/008 , A61F9/00804 , A61F9/00817 , A61F2009/00844 , A61F2009/00872 , A61F2009/00882
摘要： Enhancement of the alignment between the eye and a laser beam of a laser eye surgery system using a visual fixation system, the fixation system often having an adjustable optical train. The optical train of the fixation system allows an eye having a significant refractive error to be accurately focused at a fixation target. To accommodate the refractive error, the adjustable optical train will often project an image of the target so that the projected image is in focus in front of or behind the plane of the patient's eye.
摘要翻译：使用视觉固定系统增强眼睛和激光眼睛手术系统的激光束之间的对准，该固定系统通常具有可调整的光学列车。固定系统的光学系统允许具有显着的折射误差的眼睛准确地聚焦在固定目标上。为了适应折射误差，可调节的光学列车将经常投射目标的图像，使得投影图像在患者眼睛的平面前方或后方聚焦。

8. 发明申请

US20050049582A1 Method and apparatus for fractional photo therapy of skin 审中-公开
$Method and apparatus for fractional photo therapy of skin$
标题翻译：皮肤分光疗法的方法和装置
公开(公告)号：US20050049582A1
公开(公告)日：2005-03-03
申请号：US10888356
申请日：2004-07-09
申请人： Leonard DeBenedictis , G. Herron , Robert Sink , David Eimerl , Vladimir Lemberg , George Voevodkin , Michael Black
发明人： Leonard DeBenedictis , G. Herron , Robert Sink , David Eimerl , Vladimir Lemberg , George Voevodkin , Michael Black
IPC分类号： A61B5/00 , A61B17/00 , A61B18/20
CPC分类号： A61B18/20 , A61B18/203 , A61B2017/00057 , A61B2018/00452 , A61B2018/0047 , A61B2018/20351 , A61B2018/20359 , A61B2018/205545 , A61B2018/2075 , A61B2018/208
摘要： A method and apparatus for providing fractional treatment of tissue (e.g., skin) using lasers is disclosed. The method involves creating one or more microscopic treatment zones of necrotic tissue and thermally-altered tissue and intentionally leaving viable tissue to surround the microscopic treatment zones. The dermatological apparatus includes one or more light sources and a delivery system to generate the microscopic treatment zones in a predetermined pattern. The microscopic treatment zones may be confined to the epidermis, dermis or span the epidermal-dermal junction, and further the stratum corneum above the microscopic treatment zones may be spared.
摘要翻译：公开了一种使用激光提供对组织（例如皮肤）的分数次处理的方法和装置。该方法包括创建坏死组织和热改变组织的一个或多个微观治疗区域，并有意地留下活组织以包围微观治疗区域。皮肤病学装置包括一个或多个光源和用于以预定图案产生微观治疗区的递送系统。微观处理区域可能被限制在表皮，真皮层或跨越表皮 - 皮肤接合处，并且可以避免在微观处理区域上方的角质层。

9. 发明授权

US5786924A Method and apparatus for treating a surface with a scanning laser beam having an improved intensity cross-section 失效
公开(公告)号：US5786924A
公开(公告)日：1998-07-28
申请号：US700685
申请日：1996-08-12
申请人： Michael Black , Vladimir Lemberg
发明人： Michael Black , Vladimir Lemberg
IPC分类号： A61B17/00 , A61B18/20 , G02B26/10 , G02B26/08
CPC分类号： G02B26/10 , A61B18/203 , G02B26/101 , A61B18/20 , A61B2017/00747 , A61B2018/00452 , A61B2018/2025 , A61B2018/2095 , Y10S359/90
摘要： A method and apparatus are disclosed for laser treatment of surfaces, such as tissue. In a preferred embodiment, the invention employs a unique reflective optical delivery system which produces an improved beam intensity cross-section which reduces thermal injury, increases the precision of the tissue interaction and allows the creation of craters with decreased sizes. Reflective optics provide precise, single-layer vaporization at low power levels without thermal injury to the underlying papillary dermis. Movable optical elements focus and direct the laser beam in a scanning pattern to treat a large area of the surface.

10. 发明授权

US09078680B2 System and method for microablation of tissue 有权
标题翻译：组织微消融的系统和方法
公开(公告)号：US09078680B2
公开(公告)日：2015-07-14
申请号：US12799064
申请日：2010-04-15
申请人： Vladimir Lemberg , Ray Choye
发明人： Vladimir Lemberg , Ray Choye
IPC分类号： A61N5/06 , A61B18/20 , A61B17/00 , A61B18/00
CPC分类号： A61B18/203 , A61B2017/00057 , A61B2018/00452 , A61B2018/00458 , A61B2018/00577 , A61B2018/00642 , A61B2018/00994
摘要： The present invention generally relates to the field of laser treatment of tissue, and particularly, to a system and method for creating microablated channels in skin. The present invention is more particularly directed to treating subsurface tissue through the created channels.
摘要翻译：本发明一般涉及组织的激光治疗领域，特别涉及用于在皮肤中产生微细通道的系统和方法。本发明更具体地涉及通过所产生的通道处理地下组织。

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