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31. 发明申请

US20150223791A1 CLOSING OPENINGS IN ANATOMICAL TISSUE 有权
标题翻译：在解剖组织中闭合开口
公开(公告)号：US20150223791A1
公开(公告)日：2015-08-13
申请号：US14694521
申请日：2015-04-23
申请人： Kardium Inc.
发明人： Samuel LICHTENSTEIN
IPC分类号： A61B17/00 , A61B17/08 , A61B17/10
CPC分类号： A61B17/0057 , A61B17/00234 , A61B17/068 , A61B17/08 , A61B17/10 , A61B2017/00477 , A61B2017/00557 , A61B2017/00579 , A61B2017/00592 , A61B2017/0061 , A61B2017/00623 , A61B2017/00668 , A61B2017/22068 , A61B2017/2927 , A61B2090/08021
摘要： A device for closing at least one opening leading to an anatomical cavity is delivered via a catheter positioned in a first opening leading to the anatomical cavity. An orientation control unit is positioned within the anatomical cavity. The orientation control unit defines an orientation of a portion of a tissue surface within the anatomical cavity that is skewed with respect to the first opening and orients a closure member of the device with the tissue surface. An occluding member and a constricting unit of the device are positioned within the anatomical cavity with the occluding member blocking a portion of an opening that is constricted by the constricting unit. An intermediate member of the device is positioned within the anatomical cavity and a closure unit employing at least one piercing element pierces through the intermediate member into a tissue wall surrounding the anatomical cavity.
摘要翻译：用于关闭通向解剖腔的至少一个开口的装置经由定位在通向解剖腔的第一开口中的导管递送。定向控制单元位于解剖腔内。取向控制单元限定解剖腔内的组织表面的一部分相对于第一开口倾斜并使组织表面的封闭构件定向。装置的闭塞构件和收缩单元定位在解剖腔内，阻塞构件阻塞由收缩单元收缩的开口的一部分。装置的中间构件定位在解剖腔内，并且使用至少一个刺穿元件的闭合单元穿过中间构件穿过围绕解剖腔的组织壁。

32. 发明申请

US20150196300A1 RETRIEVAL WIRE CENTERING DEVICE 有权
标题翻译：检索线中心设备
公开(公告)号：US20150196300A1
公开(公告)日：2015-07-16
申请号：US14586707
申请日：2014-12-30
申请人： BOSTON SCIENTIFIC SCIMED INC.
发明人： Brian J. Tischler , Christopher J. Clark , Mark McPhail , Dennis A. Peiffer , Burns P. Doran
IPC分类号： A61B17/12
CPC分类号： A61B17/12122 , A61B17/0057 , A61B17/12172 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00623 , A61B2017/1205 , A61B2017/12095
摘要： An occlusive implant system may include a catheter having a lumen extending therethrough, a core wire slidably and rotatably disposed within the lumen, the core wire having a threaded member disposed at a distal end, and a medical implant having an expandable frame, an occlusive element disposed on the frame, and a threaded insert coupled to a proximal portion of the frame, wherein the threaded member is removably coupled to the threaded insert.
摘要翻译：闭塞植入系统可以包括具有延伸穿过其中的内腔的导管，可滑动和可旋转地设置在内腔内的芯线，芯线具有设置在远端的螺纹构件，以及具有可扩张框架的医疗植入物，闭塞元件设置在框架上，以及联接到框架的近侧部分的螺纹插入件，其中螺纹构件可拆卸地联接到螺纹插入件。

33. 发明申请

US20140371787A1 VASCULAR CLOSURE DEVICE 有权
标题翻译：血管闭合装置
公开(公告)号：US20140371787A1
公开(公告)日：2014-12-18
申请号：US14473649
申请日：2014-08-29
申请人： Cook Medical Technologies LLC
发明人： Darin G Schaeffer
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00579 , A61B2017/00592 , A61B2017/00601 , A61B2017/00615 , A61B2017/00623 , A61B2017/00668 , A61B2017/00778
摘要： A device for closure of an opening formed through a wall of a body vessel of a patient is provided, as well as an introducer system for delivery of the closure device. Various embodiments include the closure device having hook members configured to engage the tissue interior of the body vessel wall, hook members configured to engage interstitial tissue adjacent to the body vessel, a plug member to contact sealably the opening from inside the body vessel, and combinations thereof. A retraction member is removably attached to the each of the embodiments to permit manipulation of the device. Remodelable material may be included with each of the embodiments to promote quicker healing. The introducer includes a sheath that is insertable through the opening and a pusher disposed within the lumen of the sheath and movable within the sheath lumen to deploy the device.
摘要翻译：提供了用于封闭通过患者的身体容器的壁形成的开口的装置，以及用于输送封闭装置的导引器系统。各种实施例包括闭合装置，该闭合装置具有构造成接合身体血管壁的组织内部的钩构件，构造成接合邻近身体血管的间隙组织的钩构件，与身体容器内部的开口可密封地接触的塞构件，以及组合其中。缩回构件可移除地附接到每个实施例，以允许操纵装置。每个实施方案可以包括可重塑的材料以促进愈合愈合。导引器包括可插入通过开口的护套和设置在护套的内腔内的推动器，并可在护套管腔内移动以展开该装置。

34. 发明申请

US20140316458A1 Tissure Closure Device and Method 审中-公开
标题翻译：断裂装置及方法
公开(公告)号：US20140316458A1
公开(公告)日：2014-10-23
申请号：US14321476
申请日：2014-07-01
申请人： MICRO INTERVENTIONAL DEVICES, INC.
发明人： Michael P. Whitman , Peter Datcuk
IPC分类号： A61B17/00 , A61B17/04
CPC分类号： A61B17/0057 , A61B17/0401 , A61B17/0466 , A61B17/06166 , A61B17/064 , A61B17/068 , A61B17/08 , A61B2017/00243 , A61B2017/00526 , A61B2017/00535 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/0061 , A61B2017/00623 , A61B2017/00632 , A61B2017/00637 , A61B2017/00663 , A61B2017/00668 , A61B2017/00867 , A61B2017/0408 , A61B2017/0409 , A61B2017/0412 , A61B2017/0414 , A61B2017/0427 , A61B2017/0437 , A61B2017/0464 , A61B2017/0475 , A61B2017/0496 , A61B2017/0618 , A61B2017/0641 , A61B2017/0645 , A61B2017/0647 , A61B2017/081 , A61B2090/065
摘要： A device having a plurality of anchors configured to be driven into a tissue, and a closure element extending between the anchors and configured to urge the anchors toward each other, closing a wound and complying with motion of the tissue.
摘要翻译：具有构造成被驱动到组织中的多个锚固件的装置以及在锚固件之间延伸并且构造成朝向彼此推动锚固件的关闭元件，闭合伤口并且符合组织的运动。

35. 发明申请

US20140236198A1 FIXATION DEVICES, SYSTEMS AND METHODS FOR ENGAGING TISSUE 审中-公开
标题翻译：固定装置，系统和方法用于组织组织
公开(公告)号：US20140236198A1
公开(公告)日：2014-08-21
申请号：US14259826
申请日：2014-04-23
申请人： Evalve, Inc.
发明人： Eric A. GOLDFARB , Alfred H. RASCHDORF, JR. , Jaime E. SARABIA , Sylvia Wen-Chin ERICKSON , Kent D. DELL , Jan KOMTEBEDDE , Ferolyn T. POWELL
IPC分类号： A61B17/122 , A61B17/00
CPC分类号： A61B17/122 , A61B8/10 , A61B17/00234 , A61B17/04 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/0625 , A61B17/064 , A61B17/0643 , A61B17/0644 , A61B17/068 , A61B17/07207 , A61B17/08 , A61B17/10 , A61B17/1227 , A61B17/1285 , A61B17/29 , A61B18/1492 , A61B18/18 , A61B18/20 , A61B50/30 , A61B2017/00243 , A61B2017/00575 , A61B2017/00579 , A61B2017/00588 , A61B2017/00592 , A61B2017/00606 , A61B2017/00615 , A61B2017/00619 , A61B2017/00623 , A61B2017/00783 , A61B2017/00867 , A61B2017/0406 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0429 , A61B2017/0435 , A61B2017/0458 , A61B2017/0464 , A61B2017/047 , A61B2017/0472 , A61B2017/0474 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/06057 , A61B2017/06076 , A61B2017/061 , A61B2017/06171 , A61B2017/0641 , A61B2017/088 , A61B2017/2908 , A61B2017/2926 , A61F2/24 , A61F2/2442 , A61F2/2445 , A61F2/2466 , A61M25/0136 , A61M25/0138 , A61M25/0147 , A61M25/02 , A61M2025/0161
摘要： The invention provides devices, systems and methods for tissue approximation and repair at treatment sites. The devices, systems and methods of the invention will find use in a variety of therapeutic procedures, including endovascular, minimally-invasive, and open surgical procedures, and can be used in various anatomical regions, including the abdomen, thorax, cardiovascular system, heart, intestinal tract, stomach, urinary tract, bladder, lung, and other organs, vessels, and tissues. The invention is particularly useful in those procedures requiring minimally-invasive or endovascular access to remote tissue locations, where the instruments utilized must negotiate long, narrow, and tortuous pathways to the treatment site. In addition, many of the devices and systems of the invention are adapted to be reversible and removable from the patient at any point without interference with or trauma to internal tissues.
摘要翻译：本发明提供了用于在治疗部位组织近似和修复的装置，系统和方法。本发明的装置，系统和方法将用于各种治疗方法，包括血管内，微创和开放性外科手术，并可用于各种解剖学领域，包括腹部，胸部，心血管系统，心脏，肠道，胃，尿道，膀胱，肺和其他器官，血管和组织。本发明在需要微创或血管内进入远程组织位置的那些程序中特别有用，其中所使用的仪器必须协商到治疗部位的长，窄和曲折的路径。此外，本发明的许多装置和系统适于在任何点处可逆地从患者移除，而不会干扰或损伤内部组织。

36. 发明申请

US20140236186A1 TISSUE APERTURE SECURING AND SEALING APPARATUSES AND RELATED METHODS OF USE 有权
标题翻译：组合式安全保护和密封装置及相关使用方法
公开(公告)号：US20140236186A1
公开(公告)日：2014-08-21
申请号：US14259624
申请日：2014-04-23
申请人： Boston Scientific Scimed, Inc.
发明人： Paul SMITH , John B. GOLDEN , Barry WEITZNER
IPC分类号： A61B17/128
CPC分类号： A61B17/128 , A61B17/0057 , A61B17/0218 , A61B17/0469 , A61B17/0643 , A61B17/0644 , A61B2017/00349 , A61B2017/00579 , A61B2017/00584 , A61B2017/00592 , A61B2017/00623 , A61B2017/00637 , A61B2017/00659 , A61B2017/00663 , A61B2017/00668 , A61B2017/00818 , A61B2017/0414 , A61B2017/0427 , A61B2017/047 , A61B2017/0472 , A61B2017/06042 , A61B2017/0641
摘要： Embodiments of the invention may be directed to apparatuses for securing and sealing apertures in tissue and related methods of use.
摘要翻译：本发明的实施例可以涉及用于固定和密封组织中的孔和相关使用方法的装置。

37. 发明申请

US20140188157A1 MEDICAL DEVICES HAVING FIXATION ANCHOR 有权
标题翻译：具有固定锚的医疗装置
公开(公告)号：US20140188157A1
公开(公告)日：2014-07-03
申请号：US14145035
申请日：2013-12-31
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： Christopher J. Clark
IPC分类号： A61B17/12
CPC分类号： A61B17/12172 , A61B17/12109 , A61B17/12122 , A61B2017/00477 , A61B2017/00526 , A61B2017/00579 , A61B2017/00632 , A61F2/01 , A61F2/013 , A61F2002/018 , A61F2220/0016 , Y10T29/49826
摘要： A medical device including a medical device body that includes a first support structure, the medical device further comprising a first fixation anchor that includes a first anchor body extending between a first end and an opposing second end, and a hook portion extending from the first end, wherein the first anchor body engages the first support structure, and wherein the first fixation anchor is fabricated separate and apart from the medical device body. A method of making a medical device is disclosed.
摘要翻译：一种医疗装置，包括包括第一支撑结构的医疗装置主体，所述医疗装置还包括第一固定锚，所述第一固定锚具包括在第一端部和相对的第二端部之间延伸的第一锚固体，以及从所述第一端部延伸的钩部，其中所述第一锚固体接合所述第一支撑结构，并且其中所述第一固定锚与所述医疗装置主体分离制造。公开了制造医疗装置的方法。

38. 发明申请

US20140179993A1 SYSTEMS AND METHODS FOR IMPROVING CARDIAC FUNCTION 有权
标题翻译：改善心脏功能的系统和方法
公开(公告)号：US20140179993A1
公开(公告)日：2014-06-26
申请号：US14189856
申请日：2014-02-25
申请人： Miles D. ALEXANDER , Matthew L. PEASE , Barry L TEMPLIN , Serjan D. NIKOLIC
发明人： Miles D. ALEXANDER , Matthew L. PEASE , Barry L TEMPLIN , Serjan D. NIKOLIC
IPC分类号： A61M1/10
CPC分类号： A61F2/2487 , A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B2017/00243 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00615 , A61B2017/00632 , A61B2017/00867 , A61B2017/0649 , A61B2017/12095 , A61M1/10 , A61M1/1003 , A61M1/1008 , A61M1/1068 , A61M1/12 , A61M1/122 , A61M2205/32
摘要： A system for improving cardiac function is provided. A foldable and expandable frame having at least one anchoring formation is attached to an elongate manipulator and placed in a catheter tube while folded. The tube is inserted into a left ventricle of a heart where the frame is ejected from the tube and expands in the left ventricle. Movements of the elongate manipulator cause the anchor to penetrate the heart muscle and the elongate manipulator to release the frame. The installed frame minimizes the effects of an akinetic portion of the heart forming an aneurysmic bulge. Devices and methods are described herein which are directed to the treatment of a patient's heart having, or one which is susceptible to heart failure, to improve diastolic function.
摘要翻译：提供了一种改善心脏功能的系统。具有至少一个锚固结构的可折叠和可扩张的框架附接到细长的操纵器并且在折叠时放置在导管中。将管插入心脏的左心室，其中框架从管中弹出并在左心室中扩张。细长机械手的运动导致锚固体穿透心脏肌肉和细长操纵器以释放框架。安装的框架最小化形成动脉瘤隆起的心脏的运动部分的影响。本文描述了针对治疗患有心力衰竭或改善舒张功能的患者的心脏的装置和方法。

39. 发明申请

US20140114345A1 Flow Obstructor and Transapical Closure Device 有权
标题翻译：流动阻塞器和经络闭合装置
公开(公告)号：US20140114345A1
公开(公告)日：2014-04-24
申请号：US13658025
申请日：2012-10-23
申请人： MEDTRONIC VASCULAR GALWAY LIMITED
发明人： Constantin Ciobanu , Evin Donnelly , Frank Harewood , Padraig Savage
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00623 , A61B2017/00632 , A61B2017/00884
摘要： Medical devices and methods for closing an anatomical aperture in a tissue are disclosed. The medical devices can include distal and proximal support structures, which can include a plurality of anchor members. A connection element can connect the distal and proximal support structures, and be configured to twist to create a seal within the medical device. In certain embodiments, a sheath about the medical device can be retracted to expose the distal support structure, which can allow it to revert to an anchoring configuration from a delivery configuration, such that the anchor members can engage an interior surface of the tissue. After twisting the connection element to form a seal, the sheath can be further retracted to expose the proximal support structure, which can allow it to revert to an anchoring configuration from a delivery configuration, such that the anchor members can engage an exterior surface of the tissue.
摘要翻译：公开了用于关闭组织中的解剖孔的医疗装置和方法。医疗装置可以包括远端和近端支撑结构，其可以包括多个锚构件。连接元件可以连接远端和近端支撑结构，并且被构造成扭曲以在医疗装置内产生密封。在某些实施例中，围绕医疗装置的护套可以缩回以露出远侧支撑结构，其可以允许其远离输送构造而恢复到锚定构型，使得锚定构件可以接合组织的内表面。在扭转连接元件以形成密封件之后，护套可以进一步缩回以露出近端支撑结构，其可以允许其从输送构造回复到锚固构型，使得锚定构件可以接合外部表面组织。

40. 发明申请

US20140100594A1 SYSTEM AND METHOD FOR TRANSAPICAL ACCESS AND CLOSURE 审中-公开
标题翻译：用于透视访问和关闭的系统和方法
公开(公告)号：US20140100594A1
公开(公告)日：2014-04-10
申请号：US13725903
申请日：2012-12-21
申请人： ENTOURAGE MEDICAL TECHNOLOGIES, INC.
发明人： Frank LITVACK , John F. SHANLEY , Alan E. SHLUZAS , Stephen H. DIAZ , Gary STEESE-BRADLEY
IPC分类号： A61B17/34
CPC分类号： A61B17/3423 , A61B17/00234 , A61B17/0057 , A61B17/0218 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/08 , A61B17/10 , A61B17/3468 , A61B90/30 , A61B90/361 , A61B2017/00243 , A61B2017/00247 , A61B2017/00349 , A61B2017/00579 , A61B2017/00592 , A61B2017/00601 , A61B2017/00606 , A61B2017/00615 , A61B2017/00619 , A61B2017/00623 , A61B2017/00637 , A61B2017/00654 , A61B2017/00668 , A61B2017/0237 , A61B2017/0414 , A61B2017/0427 , A61B2017/0464 , A61B2017/0472 , A61B2017/0496 , A61B2017/06009 , A61B2017/06023 , A61B2017/06042 , A61B2017/06076 , A61B2017/06176 , A61B2017/22067 , A61B2017/22069 , A61B2017/306 , A61B2017/3425 , A61B2017/3445 , A61B2017/3484 , A61B2017/3488 , A61B2090/036 , A61B2090/306 , A61B2090/3735
摘要： Embodiments are described for creating and closing tissue access ports, such as transapical access ports, which involve placement of an introducer across the subject tissue structure, and deployment of a controllable port closure device assembly configured to remain in place with a ratcheting mechanism, and to hold the tissue surrounding the previous access port location closed against a sealing disc with proximal and distal strut assemblies, after the introducer has been removed.
摘要翻译：描述了用于创建和关闭组织进入端口（例如经验性访问端口）的实施例，其涉及导引器跨越对象组织结构的放置，以及配置成利用棘轮机构保持就位的可控制的端口闭合装置组件的展开，以及在引导器已经被移除之后，将围绕先前进入端口位置的组织保持靠近具有近端和远端支柱组件的密封盘。

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