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31. 发明申请

US20110021976A1 METHOD AND DEVICE FOR TISSUE REMOVAL AND FOR DELIVERY OF A THERAPEUTIC AGENT OR BULKING AGENT 有权
标题翻译：用于组织去除和用于递送治疗剂或者破坏剂的方法和装置
公开(公告)号：US20110021976A1
公开(公告)日：2011-01-27
申请号：US12893168
申请日：2010-09-29
申请人： Jamie (Jianmin) Li , Weenna Bucay-Couto
发明人： Jamie (Jianmin) Li , Weenna Bucay-Couto
IPC分类号： A61M37/00 , A61B17/3205
CPC分类号： A61M37/00 , A61B10/0241 , A61B17/22 , A61B17/32002 , A61B2017/00274 , A61B2017/00685 , A61B2017/320775 , A61B2018/00547
摘要： According to an aspect of the present invention, a medical device is provided, which comprises the following: (a) a hollow elongate body (e.g., a elongate cylinder, such as a needle) having distal and proximal ends; and (b) a rotatable member comprising a tissue morselizer and an elongate shaft (e.g., an auger-like tissue-drilling bit). In the devices of the present invention, the elongate shaft is disposed within the hollow elongate body and cooperates with the hollow elongate body to (i) advance material (e.g., morselated tissue) toward the proximal end of the hollow elongate body when the shaft is rotated in a first direction, and (ii) advance material (e.g., a therapeutic agent and/or a bulking agent) toward the distal end of the hollow elongate body when the shaft is rotated in a second direction that is opposite the first direction. According to another aspect of the invention a method of treatment is provided that comprises: (a) inserting the a medical device like that above into the tissue of a patient; (b) morselizing and removing tissue from within the patient while rotating the shaft in a first direction, thereby creating a void within the patient; and (c) introducing a therapeutic agent and/or a bulking agent into the void.
摘要翻译：根据本发明的一个方面，提供一种医疗装置，其包括：（a）具有远端和近端的中空细长体（例如细长圆柱体，例如针头）; 和（b）可旋转构件，其包括组织修整器和细长轴（例如，螺旋状组织钻头）。在本发明的装置中，细长轴设置在中空细长主体内并且与中空细长主体配合以（i）当轴是轴向时将材料（例如，微小的组织）推向中空细长体的近端在第一方向上旋转，并且（ii）当轴沿与第一方向相反的第二方向旋转时，将材料（例如，治疗剂和/或填充剂）推向中空细长体的远端。根据本发明的另一方面，提供了一种治疗方法，其包括：（a）将如上所述的医疗装置插入患者的组织中; （b）在沿着第一方向旋转所述轴的同时从所述患者内进行细致和去除组织，从而在所述患者体内产生空洞; 和（c）将治疗剂和/或填充剂引入空隙中。

32. 发明申请

US20110009748A1 TRANSPERINEAL PROSTATE BIOPSY SYSTEM AND METHODS 审中-公开
标题翻译： TRANSPERINE PROSTATE BIOPSY系统和方法
公开(公告)号：US20110009748A1
公开(公告)日：2011-01-13
申请号：US12814007
申请日：2010-06-11
申请人： Damien GREENE , Ofri VAISMAN , Natan KARMON
发明人： Damien GREENE , Ofri VAISMAN , Natan KARMON
IPC分类号： A61B8/13 , A61B18/02 , A61B10/02
CPC分类号： A61B8/08 , A61B8/12 , A61B10/0241 , A61B18/02 , A61B90/11 , A61B2018/0231 , A61B2090/378
摘要： Method and systems for performing ultrasound guided transperineal prostate biopsies. A template having a plurality of apertures and attached to a transrectal ultrasound probe is used for planning and guiding the biopsy. The template is placed against the patient's perineum and transverse ultrasound images having a projected template image are displayed. Planned biopsy locations are marked on the projected aperture image and biopsy samples are obtained through the corresponding template apertures. Sagittal ultrasounds may be viewed to ensure the correct depth of the biopsy needle during the biopsy. Information about the location of the biopsy sample can be recorded by identifying the template aperture through which the biopsy was obtained. Stored biopsy location information can be used for planning later treatments which can use a template having the same set of apertures.
摘要翻译：用于执行超声引导经腹导管前列腺活检的方法和系统。使用具有多个孔并连接到经直肠超声探头的模板来规划和引导活组织检查。将模板放置在患者的会阴上，并且显示具有投影模板图像的横向超声图像。计划的活检位置在投影的孔径图像上标记，并通过相应的模板孔获得活检样本。可以观察矢状超声，以确保活检期间活检针的正确深度。通过识别通过其获得活组织检查的模板孔可以记录关于活检样本的位置的信息。存储的活检位置信息可以用于规划可以使用具有相同组孔径的模板的后续处理。

33. 发明授权

US07264596B2 Methods and apparatus for securing medical instruments to desired locations in a patient's body 有权
标题翻译：将医疗器械固定在患者身体所需位置的方法和装置
公开(公告)号：US07264596B2
公开(公告)日：2007-09-04
申请号：US10010213
申请日：2001-12-04
申请人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick
发明人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick
IPC分类号： A61B10/00 , A61B17/32
CPC分类号： A61B10/04 , A61B10/02 , A61B10/0241 , A61B10/0266 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/12 , A61B18/14 , A61B18/1477 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B90/39 , A61B2017/320064 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2019/5487 , A61B2019/5491 , A61B2090/3908 , A61B2090/3991
摘要： Devices and methods are provided for securely affixing a medical instrument to desired tissue in a patient's body, using a fixation agent. Such medical instruments may comprise localization wires or tissue acquisition instruments, such as biopsy instruments, for example. In the case of tissue acquisition instruments, the inventors have discovered significant advantages for securely affixing the distal end of the tissue acquisition instrument to a particular tissue target area. For example, such an approach permits the imaging environment to be uncoupled from the procedural environment so that expensive and often unavailable imaging equipment, such as stereotactic imaging equipment, need not be used. In a preferred embodiment, a bonding agent, such as adhesive, surgical glue, or a solvent, is used as the fixation agent.
摘要翻译：提供了设备和方法，用于使用固定剂将医疗器械牢固地固定在患者体内的期望的组织上。这样的医疗器械可以包括定位线或组织采集器械，例如活检器械。在组织采集仪器的情况下，本发明人已经发现了将组织采集仪器的远端牢固地固定到特定组织靶区域的显着优点。例如，这种方法允许成像环境与程序环境分离，从而不需要使用诸如立体定向成像设备之类的昂贵和经常不可用的成像设备。在优选的实施方案中，使用粘合剂，例如粘合剂，手术胶或溶剂作为固定剂。

34. 发明申请

US20050245842A1 Methods and apparatus for securing medical instruments to desired locations in a patient's body 有权
标题翻译：将医疗器械固定在患者身体所需位置的方法和装置
公开(公告)号：US20050245842A1
公开(公告)日：2005-11-03
申请号：US11179277
申请日：2005-07-11
申请人： Fred Burbank , Paul Lubock , Michael Jones , Richard Quick
发明人： Fred Burbank , Paul Lubock , Michael Jones , Richard Quick
IPC分类号： A61B10/02 , A61B10/00 , A61B17/00 , A61B17/22 , A61B17/32 , A61B17/34 , A61B18/12 , A61B18/14 , A61B19/00 , A61F2/82
CPC分类号： A61B10/04 , A61B10/02 , A61B10/0241 , A61B10/0266 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/12 , A61B18/14 , A61B18/1477 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B90/39 , A61B2017/320064 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2019/5487 , A61B2019/5491 , A61B2090/3908 , A61B2090/3991
摘要： Devices and methods are provided for securely affixing a medical instrument to desired tissue in a patient's body, using a fixation agent. Such medical instruments may comprise localization wires or tissue acquisition instruments, such as biopsy instruments, for example. In the case of tissue acquisition instruments, the inventors have discovered significant advantages for securely affixing the distal end of the tissue acquisition instrument to a particular tissue target area. For example, such an approach permits the imaging environment to be uncoupled from the procedural environment so that expensive and often unavailable imaging equipment, such as stereotactic imaging equipment, need not be used. In a preferred embodiment, a bonding agent, such as adhesive, surgical glue, or a solvent, is used as the fixation agent.
摘要翻译：提供了设备和方法，用于使用固定剂将医疗器械牢固地固定在患者体内的期望的组织上。这样的医疗器械可以包括定位线或组织采集器械，例如活检器械。在组织采集仪器的情况下，本发明人已经发现了将组织采集仪器的远端牢固地固定到特定组织靶区域的显着优点。例如，这种方法允许成像环境与程序环境分离，从而不需要使用诸如立体定向成像设备之类的昂贵和经常不可用的成像设备。在优选的实施方案中，使用粘合剂，例如粘合剂，手术胶或溶剂作为固定剂。

35. 发明申请

US20050203440A1 System and method for tissue sampling and therapeutic treatment 有权
标题翻译：用于组织取样和治疗的系统和方法
公开(公告)号：US20050203440A1
公开(公告)日：2005-09-15
申请号：US10798085
申请日：2004-03-11
申请人： Barry Gellman , Jozef Slanda
发明人： Barry Gellman , Jozef Slanda
IPC分类号： A61B10/00 , A61B10/02 , A61B17/00 , A61B17/22 , A61B17/32 , A61B17/34 , A61B18/14 , A61B19/00
CPC分类号： A61B10/0275 , A61B10/0241 , A61B10/0283 , A61B17/3203 , A61B17/34 , A61B18/1477 , A61B90/92 , A61B2017/00464 , A61B2017/22082 , A61B2018/1425 , A61B2018/143 , A61B2018/1432 , A61B2090/0801 , A61B2090/3908
摘要： A biopsy system comprises a first placeholder element insertable through tissue to a first selected location in a patient's body, the first placeholder element including a first element guide and a tissue sampling element insertable to the first selected location via the first element guide for obtaining a sample of tissue from the first selected location, the tissue sampling element being removable from the first element guide while leaving the first placeholder element at the first selected location in combination with a tissue treatment element insertable to the first selected location via the first element guide.
摘要翻译：活检系统包括可穿过组织插入患者体内的第一选定位置的第一占位符元件，第一占位符元件包括第一元件引导件和可经由第一元件引导件插入到第一选定位置的组织取样元件，用于获得样本的组织采样元件可从第一元件引导件移除，同时通过第一元件引导件将第一占位符元件与可插入到第一选定位置的组织处理元件组合在第一选定位置。

36. 发明申请

US20050010203A1 Medical probe device and method 有权
公开(公告)号：US20050010203A1
公开(公告)日：2005-01-13
申请号：US10910333
申请日：2004-08-03
申请人： Stuart Edwards , Ronald Lax , Ingemar Lundquist , Hugh Sharkey
发明人： Stuart Edwards , Ronald Lax , Ingemar Lundquist , Hugh Sharkey
IPC分类号： A61B5/01 , A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61M1/00 , A61M3/02 , A61M25/00 , A61M25/092 , A61M25/14 , A61N1/06 , A61N1/40 , A61N5/02 , A61N5/04 , A61N5/06 , A61B18/04
CPC分类号： A61N5/02 , A61B10/02 , A61B10/0241 , A61B18/00 , A61B18/082 , A61B18/1206 , A61B18/1477 , A61B18/148 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/0075 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00869 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1412 , A61B2018/1425 , A61B2018/1861 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61F2007/0054 , A61M3/0279 , A61M25/0068 , A61M25/0069 , A61M25/008 , A61M25/0082 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/009 , A61M2025/0096 , A61M2025/018 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/04 , A61N5/045
摘要： A medical probe device comprises a catheter having a stylet guide housing with one or more stylet ports in a side wall thereof and a stylet guide for directing a flexible stylet outward through the stylet port and through intervening tissue at a preselected, adjustable angle to a target tissue. The total catheter assembly includes a stylet guide lumen communicating with the stylet port and a stylet positioned in said stylet guide lumen for longitudinal movement from the port through intervening tissue to a target tissue. The stylet can be an electrical conductor enclosed within a non-conductive layer, the electrical conductor being a radiofrequency electrode. Preferably, the non-conductive layer is a sleeve which is axially moveable on the electrical conductor to expose a selected portion of the electrical conductor surface in the target tissue. The stylet can also be a microwave antenna. The stylet can also be a hollow tube for delivering treatment fluid to the target tissue. It can also include a fiber optic cable for laser treatment. The catheter can include one or more inflatable balloons located adjacent to the stylet port for anchoring the catheter or dilation. Ultrasound transponders and temperature sensors can be attached to the probe end and/or stylet. The stylet guide can define a stylet path from an axial orientation in the catheter through a curved portion to a lateral orientation at the stylet port.

37. 发明授权

US06540693B2 Methods and apparatus for securing medical instruments to desired locations in a patients body 有权
标题翻译：将医疗器械固定在患者身体所需位置的方法和装置
公开(公告)号：US06540693B2
公开(公告)日：2003-04-01
申请号：US09146185
申请日：1998-09-01
申请人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick
发明人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick
IPC分类号： A61B1000
CPC分类号： A61B10/04 , A61B10/02 , A61B10/0241 , A61B10/0266 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/12 , A61B18/14 , A61B18/1477 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B90/39 , A61B2017/320064 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2019/5487 , A61B2019/5491 , A61B2090/3908 , A61B2090/3991
摘要： Devices and methods are provided for securely affixing a medical instrument to desired tissue in a patient's body, using a fixation agent. Such medical instruments may comprise localization wires or tissue acquisition instruments, such as biopsy instruments, for example. In the case of tissue acquisition instruments, the inventors have discovered significant advantages for securely affixing the distal end of the tissue acquisition instrument to a particular tissue target area. For example, such an approach permits the imaging environment to be uncoupled from the procedural environment so that expensive and often unavailable imaging equipment, such as stereotactic imaging equipment, need not be used. In a preferred embodiment, a bonding agent, such as adhesive, surgical glue, or a solvent, is used as the fixation agent.
摘要翻译：提供了设备和方法，用于使用固定剂将医疗器械牢固地固定在患者体内的期望的组织上。这样的医疗器械可以包括定位线或组织采集器械，例如活检器械。在组织采集仪器的情况下，本发明人已经发现了将组织采集仪器的远端牢固地固定到特定组织靶区域的显着优点。例如，这种方法允许成像环境与程序环境分离，从而不需要使用诸如立体定向成像设备之类的昂贵和经常不可用的成像设备。在优选的实施方案中，使用粘合剂，例如粘合剂，手术胶或溶剂作为固定剂。

38. 发明申请

US20010011161A1 Medical probe with stylets 失效
标题翻译：医疗探头与风格
公开(公告)号：US20010011161A1
公开(公告)日：2001-08-02
申请号：US09819151
申请日：2001-03-27
申请人： VIDAMED, INC.
发明人： Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James Allen Baker JR.
IPC分类号： A61B017/20
CPC分类号： A61B10/0233 , A61B1/00188 , A61B10/02 , A61B10/0241 , A61B10/0275 , A61B10/06 , A61B18/00 , A61B18/14 , A61B18/1477 , A61B18/148 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/0075 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00869 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61B2217/005 , A61B2217/007 , A61K31/465 , A61M3/0279 , A61M25/0032 , A61M25/0045 , A61M25/008 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/009 , A61M2025/0096 , A61M2025/018 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/04 , A61N5/045
摘要： A medical probe device of this invention comprising a catheter having a control end and a probe end. The probe end includes a stylet guide housing having at least one stylet port and stylet guide means for directing a flexible stylet outward through at least one stylet port and through intervening tissue to targeted tissues. A stylet is positioned in at least one of said stylet guide means, the stylet comprising a non-conductive sleeve having a RF electrode lumen and an optional a fluid supply lumen and a temperature sensor lumen therein. At least one portion of an opposed surface of the electrode lumen and the electrode can be spaced apart to define a liquid supply passageway for delivery of medicament liquid. The RF electrode enclosed within the non-conductive sleeve has a distal length optionally having at least one current focusing groove means thereon and a distal tip shaped to focus current crowding on its terminal end, whereby Rf current passing therefrom into surrounding tissue forms a lesion extending outward from the groove and tip. The focusing groove means can be a plurality of annular focusing grooves or a spiral focusing groove thereon.
摘要翻译：本发明的医疗探针装置包括具有控制端和探针端的导管。探针端部包括具有至少一个探针端口和探针引导装置的探针引导壳体，用于将柔性探针向外引导通过至少一个通管孔，并通过介入组织引导到靶组织。探针定位在所述探针引导装置中的至少一个上，所述探针包括具有RF电极腔和可选的流体供应管腔和其中的温度传感器腔的非导电套管。电极腔和电极的相对表面的至少一部分可以间隔开以限定用于输送药液的液体供应通道。封闭在非导电套筒内的RF电极具有任选地在其上具有至少一个电流聚焦槽装置的远端长度，以及形成为将电流拥挤聚焦在其末端上的远端，其中从其进入周围组织的Rf电流形成延伸的病变从凹槽和尖端向外。聚焦槽装置可以是多个环形聚焦槽或其上的螺旋形聚焦槽。

39. 发明授权

US5895370A Medical probe (with stylets) device 失效
标题翻译：医用探头（带样式）装置
公开(公告)号：US5895370A
公开(公告)日：1999-04-20
申请号：US779421
申请日：1997-01-07
申请人： Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James Allen Baker, Jr.
发明人： Stuart D. Edwards , Hugh R. Sharkey , Ingemar H. Lundquist , Ronald G. Lax , James Allen Baker, Jr.
IPC分类号： A61B18/12 , A61B1/00 , A61B5/01 , A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61K31/465 , A61M1/00 , A61M3/02 , A61M25/00 , A61M25/14 , A61N1/06 , A61N1/40 , A61N5/02 , A61N5/04 , A61N5/06 , A61B17/39
CPC分类号： A61B10/0233 , A61B10/0275 , A61B10/06 , A61B18/00 , A61B18/1477 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61K31/465 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/045 , A61B1/00188 , A61B10/02 , A61B10/0241 , A61B18/14 , A61B18/1442 , A61B18/148 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/0075 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00869 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61B2217/005 , A61B2217/007 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/009 , A61M2025/0096 , A61M2025/018 , A61M25/0032 , A61M25/0045 , A61M25/008 , A61M3/0279 , A61N5/04
摘要： A medical probe device of this invention comprising a catheter having a control end and a probe end. The probe end includes a stylet guide housing having at least one stylet port and stylet guide means for directing a flexible stylet outward through at least one stylet port and through intervening tissue to targeted tissues. A stylet is positioned in at least one of said stylet guide means, the stylet comprising a non-conductive sleeve having a RF electrode lumen and an optional a fluid supply lumen and a temperature sensor lumen therein. At least one portion of an opposed surface of the electrode lumen and the electrode can be spaced apart to define a liquid supply passageway for delivery of medicament liquid. The RF electrode enclosed within the non-conductive sleeve has a distal length optionally having at least one current focusing groove means thereon and a distal tip shaped to focus current crowding on its terminal end, whereby Rf current passing therefrom into surrounding tissue forms a lesion extending outward from the groove and tip. The focusing groove means can be a plurality of annular focusing grooves or a spiral focusing groove thereon.
摘要翻译：本发明的医疗探针装置包括具有控制端和探针端的导管。探针端部包括具有至少一个探针端口和探针引导装置的探针引导壳体，用于将柔性探针向外引导通过至少一个通管孔，并通过介入组织引导到靶组织。探针定位在所述探针引导装置中的至少一个上，所述探针包括具有RF电极腔和可选的流体供应管腔和其中的温度传感器腔的非导电套管。电极腔和电极的相对表面的至少一部分可以间隔开以限定用于输送药液的液体供应通道。封闭在非导电套筒内的RF电极具有任选地在其上具有至少一个电流聚焦槽装置的远端长度，以及形成为将电流拥挤聚焦在其末端上的远端，其中从其进入周围组织的Rf电流形成延伸的病变从凹槽和尖端向外。聚焦槽装置可以是多个环形聚焦槽或其上的螺旋形聚焦槽。

40. 发明授权

US5848986A Medical probe with electrode guide for transurethral ablation 失效
标题翻译：带电极导管的医用探头用于经尿道消融
公开(公告)号：US5848986A
公开(公告)日：1998-12-15
申请号：US667452
申请日：1996-06-21
申请人： Ingemar H. Lundquist , Stuart D. Edwards
发明人： Ingemar H. Lundquist , Stuart D. Edwards
IPC分类号： A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61M1/00 , A61M3/02 , A61M25/00 , A61M25/01 , A61M25/092 , A61N1/06 , A61N1/40 , A61N5/04 , A61B17/20
CPC分类号： A61B10/0233 , A61B10/0275 , A61B10/06 , A61B17/3403 , A61B17/3417 , A61B17/3478 , A61B18/00 , A61B18/1477 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61M25/0136 , A61M25/0138 , A61M25/0147 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/045 , A61B10/02 , A61B10/0241 , A61B18/14 , A61B18/1442 , A61B18/148 , A61B18/1492 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00101 , A61B2017/00106 , A61B2017/00123 , A61B2017/00181 , A61B2017/00194 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00469 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00083 , A61B2018/00095 , A61B2018/00101 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1425 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/378 , A61B2090/3782 , A61B2090/3786 , A61B2090/3925 , A61B2217/005 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/0096 , A61M2025/018 , A61M25/0068 , A61M25/008 , A61M25/0082 , A61M3/0279 , A61N5/04
摘要： A medical probe for the treatment by radio frequency ablation of a target volume in tissue of a human having a urethral channel extending into a base of a bladder along a longitudinal axis. The probe comprises an elongate probe member having proximal and distal extremities and sized so that it can be introduced into the urethra. The elongate probe member has a passage extending from the proximal extremity to the distal extremity. Guide cannulae are mounted in the passage of the elongate probe member and have proximal and distal extremities with the distal extremities of the guide cannulae being in the vicinity of the distal extremity of the elongate probe member. Each of the guide cannulae has a lumen extending therethrough from the proximal extremity to the distal extremity. A radio frequency conductive electrode is disposed in each lumen. A control handle is secured to the proximal extremity of the elongate probe member. The control handle is connected to each radio frequency electrode whereby each radio frequency electrode can be advanced and retracted.
摘要翻译：一种用于通过射线消融处理的医疗探针，其具有沿着纵向轴线延伸到膀胱的基部中的具有尿道的人的组织中的靶体积。探针包括具有近端和远端的细长探针部件，并且其尺寸使其能够被引入到尿道中。细长的探针构件具有从近端延伸到远端的通道。引导套管安装在细长探针构件的通道中，并且具有近端和远端，引导套管的远端在细长探针构件的远端附近。每个引导套管具有从近端到远端延伸穿过的内腔。射频导电电极设置在每个管腔中。控制手柄固定到细长探针构件的近端。控制手柄连接到每个射频电极，由此每个射频电极可以前进和后退。

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