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31. 发明授权

US07384642B2 Canine influenza vaccines 有权
公开(公告)号：US07384642B2
公开(公告)日：2008-06-10
申请号：US11211983
申请日：2005-08-25
申请人： Jules Maarten Minke , Kemal Karaca , Jiansheng Yao
发明人： Jules Maarten Minke , Kemal Karaca , Jiansheng Yao
IPC分类号： A61K39/145 , A61K39/00 , A61K39/285
CPC分类号： C12Q1/6888 , C12Q2600/158
摘要： The present invention encompasses influenza vaccines, in particular canine influenza vaccines. The vaccine may be a recombinant poxvirus vaccine or an inactivated vaccine. The invention also encompasses recombinant poxvirus vectors encoding and expressing influenza antigens, epitopes or immunogens which can be used to protect animals, in particular dogs, against influenza.

32. 发明授权

US07351815B2 Canine pre-proGHRH and mature GHRH genes 有权
标题翻译：犬前proGHRH和成熟GHRH基因
公开(公告)号：US07351815B2
公开(公告)日：2008-04-01
申请号：US10838122
申请日：2004-05-03
申请人： Laurent Bernard Fisher , Nathalie Michele Cachet , Simona Barzu-Le Roux
发明人： Laurent Bernard Fisher , Nathalie Michele Cachet , Simona Barzu-Le Roux
IPC分类号： C07H21/00 , C07K14/60
CPC分类号： C07K14/60 , A61K38/00
摘要： The present invention relates to a canine pre-proGHRH polypeptide, a canine mature GHRH peptide, an isolated polynucleotide which encodes the canine pre-proGHRH or the canine mature GHRH. The invention also encompasses vectors encoding and expressing the canine pre-proGHRH or the canine GHRH which can be used to treat disease and growth hormone deficiencies by gene therapy in vertebrates, in particular in dogs.
摘要翻译：本发明涉及犬pre-proGHRH多肽，犬成熟GHRH肽，编码犬pre-proGHRH或犬成熟GHRH的分离的多核苷酸。本发明还包括编码和表达犬pre-proGHRH或犬GHRH的载体，其可用于通过脊椎动物，特别是狗中的基因治疗来治疗疾病和生长激素缺乏。

33. 发明申请

US20060002952A1 Postweaning multisystemic wasting syndrome and porcine circovirus from pigs 有权
公开(公告)号：US20060002952A1
公开(公告)日：2006-01-05
申请号：US11217562
申请日：2005-09-01
申请人： Deborah Haines , Gordon Allan , John Ellis , Brian Meehan , Edward Clark , Lori Hassard , John Harding , Catherine Charreyre , Gilles Chappuis , Francis McNeilly , Li Wang , Lorne Babiuk , Andrew Potter , Philip Willson
发明人： Deborah Haines , Gordon Allan , John Ellis , Brian Meehan , Edward Clark , Lori Hassard , John Harding , Catherine Charreyre , Gilles Chappuis , Francis McNeilly , Li Wang , Lorne Babiuk , Andrew Potter , Philip Willson
IPC分类号： C12Q1/70 , C07H21/04 , A61K39/12 , A61K48/00 , C07K14/005 , C12N15/86
CPC分类号： C07K14/005 , A61K38/00 , A61K39/00 , A61K39/12 , A61K48/00 , A61K2039/51 , A61K2039/53 , A61K2039/552 , A61K2039/70 , C12N7/00 , C12N15/86 , C12N2750/10022 , C12N2750/10034 , C12N2750/10043 , C12Q1/701
摘要： The cloning of a novel PCVII viral genome is described as is expression of proteins derived from the PCVII genome. These proteins can be used in vaccine compositions for the prevention and treatment of PCVII infections, as well as in diagnostic methods for determining the presence of PCVII infections in a vertebrate subject. Polynucleotides derived from the viral genome can be used as diagnostic primers and probes.

34. 发明申请

US20140350529A1 Sustained Release Capsules 有权
标题翻译：持续释放胶囊
公开(公告)号：US20140350529A1
公开(公告)日：2014-11-27
申请号：US14274282
申请日：2014-05-09
申请人： Merial Limited
发明人： Robert William Lachlan Holmes
IPC分类号： A61M31/00 , A61D7/00
CPC分类号： A61M31/002 , A61D7/00 , A61J3/07 , A61K9/0068 , A61K9/4808 , A61K9/4816
摘要： The invention relates to an intraruminal sustained release capsule which is capable of delivering a sustained release dose of a first medicament to an animal, as well as either or both of a dump dose of a second medicament or mineral, and an exit dose of a third medicament or mineral. The capsule can have a dissolvable overcap moulded from plasticised starch enabling a dump dose of medicament to be held between the overcap and one end of the capsule. A piston within the body of the capsule can be modified to enable it to accommodate an exit dose of medicament within its hollow interior which is aligned with an aperture at the end of the capsule which enables release of the medicaments to the rumen. After insertion of the capsule in the animal the overcap (if present) dissolves and separates from the capsule to release the dump dose of medicament. The sustained release medicament is then dispensed via the apertured end, followed by the release of the exit dose of medicament (if present).
摘要翻译：本发明涉及一种能够将第一药物的持续释放剂量递送至动物的肿瘤内缓释胶囊，以及第二种药物或矿物质的倾倒剂量和第三种药物的出口剂量中的任一种或两种药物或矿物质。胶囊可以具有由塑化淀粉模制的可溶性顶帽，从而能够将倾倒剂量的药剂保持在胶囊的顶帽和一端之间。胶囊体内的活塞可以被修改以使其能够容纳在其中空内部中的出口剂量的药物，其与胶囊末端的孔对齐，这使得药物能够释放到瘤胃。在将胶囊插入动物中之后，顶盖（如果存在）溶解并与胶囊分离以释放药物的吐出剂量。然后通过有孔端分配缓释药物，然后释放出口剂量的药物（如果存在）。

35. 发明申请

US20140341950A1 RECOMBINANT AVIAN PARAMYXOVIRUS VACCINE AND METHOD FOR MAKING AND USING THEREOF 审中-公开
标题翻译：重组禽流感疫苗及其制备和使用方法
公开(公告)号：US20140341950A1
公开(公告)日：2014-11-20
申请号：US13894582
申请日：2013-05-15
申请人： Michel Bublot , Teshome Mebatsion , Joyce Pritchard , Egbert Mundt
发明人： Michel Bublot , Teshome Mebatsion , Joyce Pritchard , Egbert Mundt
IPC分类号： A61K39/155
CPC分类号： C12N7/00 , A61K39/12 , A61K2039/5256 , A61K2039/54 , A61K2039/541 , C12N2760/18121 , C12N2760/18134 , C12N2760/18143
摘要： The present invention encompasses engineered APMV compositions or vaccines. The vaccine or composition may be a recombinant APMV composition or vaccine. The present invention encompasses methods for modifying the genome of APMV to produce recombinant APMV; modified APMV prepared by such methods; DNA and protein sequences; and methods for infecting cells and host animals with such recombinant APMV.
摘要翻译：本发明包括工程APMV组合物或疫苗。疫苗或组合物可以是重组APMV组合物或疫苗。本发明包括修饰APMV基因组以产生重组APMV的方法; 通过这种方法制备的改性APMV; DNA和蛋白质序列; 以及用这种重组APMV感染细胞和宿主动物的方法。

36. 发明授权

US08871225B2 Canine leishmania vaccine 有权
标题翻译：犬利什曼原虫疫苗
公开(公告)号：US08871225B2
公开(公告)日：2014-10-28
申请号：US12839580
申请日：2010-07-20
申请人： Laurent Bernard Fischer
发明人： Laurent Bernard Fischer
IPC分类号： A61K39/008 , C07H21/04 , A61K39/00
CPC分类号： A61K39/008 , A61K2039/53 , A61K2039/545 , Y02A50/41
摘要： The present invention provides vectors that contain and express in vivo Leishmania KMP11 or an epitope thereof that elicits an immune response in a dog against Leishmania, compositions comprising said vectors, methods of vaccination against Leishmania, and kits for use with such methods and compositions.
摘要翻译：本发明提供含有体内利什曼原虫KMP11或其表位的载体，其在狗中针对利什曼原虫引起免疫应答，包含所述载体的组合物，针对利什曼原虫接种的方法，以及用于此类方法和组合物的试剂盒。

37. 发明申请

US20140315794A1 ANTIPARISITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME 有权
标题翻译：抗生素二氢化合物及其组合物
公开(公告)号：US20140315794A1
公开(公告)日：2014-10-23
申请号：US14086712
申请日：2013-11-21
申请人： Loic Patrick Le Hir de Fallois , Hyoung Ik Lee , Douglas Edward Wilkinson , Brent Christopher Beck
发明人： Loic Patrick Le Hir de Fallois , Hyoung Ik Lee , Douglas Edward Wilkinson , Brent Christopher Beck
IPC分类号： C07D471/04 , A61K38/05 , A61K31/437 , A61K45/06 , A01N43/90 , C07K5/06 , A01N43/80
CPC分类号： C07D471/04 , A01N43/80 , A01N43/90 , A61K31/365 , A61K31/437 , A61K31/495 , A61K38/05 , A61K45/06 , C07K5/06 , A61K2300/00
摘要： The present invention relates to novel dihydroazole of formula (I) and salts thereof: Wherein R1, A1, A2, G, X and Y are as defined in the description, compositions thereof, processes for their preparation and their uses to prevent or treat parasitic infections or infestations in animals and as pesticides.
摘要翻译：本发明涉及式（I）的新型二氢唑及其盐：其中R1，A1，A2，G，X和Y如说明书中所定义，其组成，其制备方法及其用于预防或治疗寄生虫感染或感染动物和农药。

38. 发明授权

US08846569B2 Pesticidal bis-organosulfur compounds 有权
标题翻译：杀虫双有机硫化合物
公开(公告)号：US08846569B2
公开(公告)日：2014-09-30
申请号：US13511736
申请日：2010-12-05
申请人： Charles Q. Meng , Matthias Pohlman , Henricus Maria Martinus Bastiaans , Ralph Paulini , Sebastian Soergel
发明人： Charles Q. Meng , Matthias Pohlman , Henricus Maria Martinus Bastiaans , Ralph Paulini , Sebastian Soergel
IPC分类号： C07C317/28 , A01C1/06 , A01N37/34 , A01N43/40 , A01P1/00 , A61K31/275 , A61K31/44 , A61P33/00 , C07D213/57 , A01N43/653 , A01N43/82 , A01N41/10 , C07C323/60 , A01N47/02 , C07D213/64 , A01N43/56 , C07C327/42 , C07C323/65 , C07D231/12 , A01N37/36
CPC分类号： C07C323/65 , A01N37/36 , A01N41/10 , A01N43/40 , A01N43/56 , A01N43/653 , A01N43/82 , A01N47/02 , C07C323/60 , C07C327/42 , C07D213/64 , C07D231/12
摘要： The present invention provides bis-organosulfur compounds of formulae (I) and (II) and compositions comprising the compounds that are effective against animal pests, including parasites. The compounds and compositions may be used for combating parasites in or on birds and mammals and for combating pests that damage crops, plants and plant propagation material. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in birds and mammals.
摘要翻译：本发明提供式（I）和（II）的双有机硫化合物和包含对动物害虫（包括寄生虫）有效的化合物的组合物。化合物和组合物可用于对抗鸟类和哺乳动物中或鸟类上的寄生虫，并用于对付损害作物，植物和植物繁殖材料的害虫。本发明还提供了用于消除，控制和预防鸟类和哺乳动物中的寄生虫感染的改进方法。

39. 发明申请

US20140271708A1 Novel methods for providing long-term protective immunity against rabies in animals, based upon administration of replication-deficient flavivirus expressing rabies G 审中-公开
标题翻译：基于表达狂犬病的复制缺陷型黄病毒的施用，提供对动物狂犬病长期保护性免疫的新方法
公开(公告)号：US20140271708A1
公开(公告)日：2014-09-18
申请号：US13841383
申请日：2013-03-15
申请人： Frederic David
发明人： Frederic David
IPC分类号： A61K39/205
CPC分类号： A61K39/205 , A61K39/12 , A61K2039/5252 , A61K2039/5256 , A61K2039/5258 , A61K2039/552 , A61K2039/55505 , C12N2760/20134 , C12N2770/24143
摘要： The present invention relates to compositions comprising replication defective chimeric flavivirus anti-rabies vaccines, methods of producing the vaccines, and the administration of such vaccines to companion animals, including dogs. The invention further relates to methods for providing long-term protective immunity against rabies in companion animals, including dogs and cats.
摘要翻译：本发明涉及包含复制缺陷型嵌合黄病毒抗狂犬病疫苗的组合物，生产疫苗的方法以及向包括狗在内的伴侣动物施用此类疫苗。本发明还涉及用于在伴侣动物（包括狗和猫）中提供针对狂犬病的长期保护性免疫的方法。

40. 发明申请

US20140205993A1 RECOMBINANT AVIAN INFLUENZA VACCINE AND USES THEREOF 审中-公开
标题翻译：重组AVIAN流感疫苗及其用途
公开(公告)号：US20140205993A1
公开(公告)日：2014-07-24
申请号：US13744806
申请日：2013-01-18
申请人： Xuan Guo , Michel Bublot , Joyce Anita Pritchard , Lynn Dickey
发明人： Xuan Guo , Michel Bublot , Joyce Anita Pritchard , Lynn Dickey
IPC分类号： C07K14/11
CPC分类号： C07K14/005 , A61K39/12 , A61K2039/542 , A61K2039/545 , A61K2039/55566 , C07K2319/02 , C12N2710/24043 , C12N2760/16134 , C12N2760/16151 , C12N2800/22
摘要： The present invention encompasses influenza vaccines, in particular avian influenza vaccines. The vaccine may be a subunit vaccine based on the hemagglutinin of influenza. The hemagglutinin may be expressed in plants including duckweed. The invention also encompasses recombinant vectors encoding and expressing influenza antigens, epitopes or immunogens which can be used to protect animals against influenza. It encompasses also a vaccination regimen compatible with the DIVA strategy, including a prime-boost scheme using vector and subunit vaccines.
摘要翻译：本发明包括流感疫苗，特别是禽流感疫苗。疫苗可以是基于流感血凝素的亚单位疫苗。血凝素可以在植物中表达，包括浮萍。本发明还包括编码和表达可用于保护动物免受流感的流感抗原，表位或免疫原的重组载体。它还包括与DIVA策略相一致的疫苗接种方案，包括使用载体和亚单位疫苗的初次加强方案。

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