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31. 发明授权

US6125095A Luminescent recording layer holding a plurality of positive or negative charges 失效
标题翻译：保持多个正电荷或负电荷的发光记录层
公开(公告)号：US6125095A
公开(公告)日：2000-09-26
申请号：US28477
申请日：1998-02-24
申请人： Nobuhiro Gemma , Hiroyuki Hieda , Kuniyoshi Tanaka
发明人： Nobuhiro Gemma , Hiroyuki Hieda , Kuniyoshi Tanaka
IPC分类号： G11B7/244 , G03G5/02 , G11B7/0045 , G11B7/005 , G11B7/24 , G11B9/00 , G11B9/14 , G11B11/08 , G01N1/00
CPC分类号： B82Y10/00 , G03G5/0202 , G11B11/08 , G11B7/00455 , G11B7/0052 , G11B7/24 , G11B9/1409 , Y10S428/917 , Y10S977/947
摘要： This invention is characterized in that information is recorded by injecting electric charge into a charge holding region made from a donor or acceptor, and the recorded information is reproduced by using changes in luminescence characteristics of the luminescent material contained in the charge holding region or a light emitting region formed near the charge holding region, that occur in accordance with the charge condition of the charge holding region.
摘要翻译：本发明的特征在于，通过将电荷注入由施主或受体制成的电荷保持区域来记录信息，并且通过使用包含在电荷保持区域中的发光材料的发光特性或光的变化来再现记录信息在电荷保持区域附近形成的与电荷保持区域的充电状态相对应的发光区域。

32. 发明授权

US6028873A Optical device capable of functioning without a population inversion 失效
标题翻译：能够没有人口反演的光学装置
公开(公告)号：US6028873A
公开(公告)日：2000-02-22
申请号：US931846
申请日：1997-09-16
申请人： Kazushige Yamamoto , Kouichi Ichimura , Nobuhiro Gemma
发明人： Kazushige Yamamoto , Kouichi Ichimura , Nobuhiro Gemma
IPC分类号： H01S3/0933 , G02F1/35 , H01S3/00 , H01S3/05 , H01S3/094 , H01S3/16 , H01S3/14
CPC分类号： H01S3/00 , G02F1/3515 , G02F1/3523
摘要： Two mirrors comprising a resonator, arranged facing to each other interpose an EIT layer, which is a solid containing an impurity. A controlling light from a controlling light source and a pumping light from a pumping light source enter the EIT layer. A photodiode detects the intensity of an LWI laser light (a signal light outputted from the EIT layer) outputted from one of the mirrors. A filter for cutting the controlling light is provided between the photodiode and the mirror. Two kinds of lights, that is, the controlling light and the pumping light are used in all the .LAMBDA., V, .XI. type three levels. In the .LAMBDA. type three levels, the controlling light is used for supposedly exciting between the levels, and the pumping light is used for pumping electrons from the level to the level via the level. In the V type three levels, the controlling light is used for exciting between the levels, and the pumping light is used for pumping electrons from the level to the level via the level. In the .XI. type three levels, the controlling light is used for supposedly exciting between the levels, and the pumping light is used for pumping electrons from the level to the level via the level.
摘要翻译：包括彼此面对的共振器的两个反射镜插入了EIT层，其是含有杂质的固体。来自控制光源的控制光和来自泵送光源的泵浦光进入EIT层。光电二极管检测从一个反射镜输出的LWI激光（从EIT层输出的信号光）的强度。用于切割控制光的滤光器设置在光电二极管和反射镜之间。所有LAMBDA，V，XI型三级都采用两种灯光，即控制灯和抽光灯。在LAMBDA型三个级别中，控制光用于在电平之间推测的激励，并且泵浦光用于通过电平将电子从电平泵送到电平。在V型三电平中，控制光用于在电平之间激发，并且泵浦光用于通过电平将电子从电平泵送到电平。在XI型三个级别中，控制光用于在电平之间据称激发，并且泵浦光用于通过电平将电子从电平泵送到电平。

33. 发明授权

US5970039A Optical recording medium, method of recording information, method of reproducing information, apparatus for recording information, and apparatus for reproducing information 失效
标题翻译：光记录介质，记录信息的方法，再现信息的方法，用于记录信息的设备和用于再现信息的设备
公开(公告)号：US5970039A
公开(公告)日：1999-10-19
申请号：US39636
申请日：1998-03-16
申请人： Kouichi Ichimura , Kazushige Yamamoto , Nobuhiro Gemma
发明人： Kouichi Ichimura , Kazushige Yamamoto , Nobuhiro Gemma
IPC分类号： G11B7/004 , G11B7/00 , G11B7/0045 , G11B7/005 , G11B7/12 , G11B7/125 , G11B7/243 , G11B9/00 , G11B13/00 , G11B13/04
CPC分类号： G11B7/127 , G11B7/00455 , G11B7/0052 , G11B13/00 , G11B13/045 , G11B7/12
摘要： A method of recording information in an optical recording medium, which comprises two steps. In the first step, a coherent light pulse train which resonates with a transition between the first and third energy levels and coherent light which resonates with a transition between the second and third energy levels or a transition between the first and second energy levels are applied to the optical recording medium, thereby causing the light pulse train to pass through the optical recording medium. In the second step, an intensity change of an external field is supplied to the medium, while the light pulse train is passing through the optical recording medium, thereby fixing sites in a thickness direction of the medium, at which the absorption spectrum of the medium is changed.
摘要翻译：一种在光学记录介质中记录信息的方法，包括两个步骤。在第一步骤中，与第一和第三能量级之间的过渡共振的相干光脉冲串和与第二和第三能级之间的转变共振的相干光或第一和第二能级之间的转变被应用于光记录介质，从而使光脉冲串通过光记录介质。在第二步骤中，当光脉冲串通过光记录介质时，外部场的强度变化被提供给介质，从而固定介质的厚度方向上的位置，在介质的厚度方向上介质的吸收光谱改变了

34. 发明授权

US5754511A Optical information reproduction by irradiating two laser beams into a recording medium of at least three energy levels and detecting absorption or photoluminescence 失效
标题翻译：通过将两束激光照射到至少三个能级的记录介质中并检测吸收或光致发光来进行光学信息再现
公开(公告)号：US5754511A
公开(公告)日：1998-05-19
申请号：US713357
申请日：1996-09-13
申请人： Nobuhiro Gemma , Kouichi Ichimura , Kazushige Yamamoto
发明人： Nobuhiro Gemma , Kouichi Ichimura , Kazushige Yamamoto
IPC分类号： G11B7/0045 , G11B7/005 , G11B7/24 , G11B7/00 , G01N1/00
CPC分类号： G11B7/0052 , G11B7/24 , G11B7/00455 , Y10S977/951
摘要： There is provided an optical detection method comprising the steps of preparing a solid body having an energy level structure constituted by at least three energy levels, and irradiating first and second coherent light on the solid body to optically detect the physical structure of the solid body, wherein the detection step satisfies the following conditions: min(.epsilon..sub.i31)
摘要翻译：提供了一种光学检测方法，包括以下步骤：制备具有由至少三个能级构成的能级结构的固体，并且在固体上照射第一和第二相干光以光学地检测固体的物理结构，其中所述检测步骤满足以下条件：min（εi31）

35. 发明授权

US5699374A Solid-state material, method of manufacturing the solid-state material, frequency-converting element, and frequency-measuring instrument incorporating the element, and frequency modulator/amplifier incorporating the element 失效
标题翻译：固体材料，固态材料的制造方法，频率转换元件和结合该元件的频率测量仪器，以及掺入该元件的频率调制器/放大器
公开(公告)号：US5699374A
公开(公告)日：1997-12-16
申请号：US702035
申请日：1996-08-23
申请人： Kouichi Ichimura , Kazushige Yamamoto , Nobuhiro Gemma
发明人： Kouichi Ichimura , Kazushige Yamamoto , Nobuhiro Gemma
IPC分类号： H01S3/14
CPC分类号： H01S3/14
摘要： A method of manufacturing a solid-state material comprises a first step of preparing a starting material having an energy-level structure with at least first, second and third energy levels, each having a specific level width, the first energy level is the lowest of the three levels, one of the second and third energy levels changing the energy-level structure when light having a predetermined wavelength is applied to the material, and the energy-level structure remaining so changed even after the application of the light, and a second step of irradiating the starting material with a first coherent light beam resonating with transition between the first and third energy levels and a second coherent light beam resonating with transition between the second and third energy levels in a case that the third level is a level which changes the energy level structure, thereby changing a distribution of angular frequency in a plane one axis of which is a first transition angular frequency corresponding to the transition between the first and third energy levels and the other axis of which is a second transition angular frequency corresponding to the transition between the second and third energy levels, thereby to form a solid-state material having new distribution of transition angular frequency, wherein the second step includes a step of setting a spectral width of the first light beam, Rabi characteristic angular frequency for transition of the second light beam and Rabi characteristic angular frequency for transition of the second light beam within one of two inhomogeneous widths for the first and second transition angular frequencies which is broader than the other.
摘要翻译：制造固态材料的方法包括：制备具有至少具有第一，第二和第三能级的能级结构的起始材料的第一步骤，每个能级具有特定的电平宽度，第一能级是三个等级，当具有预定波长的光被施加到材料时，第二和第三能级中的一个能级改变能级结构，并且能量级结构即使在施加光之后也保持改变，并且第二级用第一和第三能级之间的跃迁共振的第一相干光束照射起始材料的步骤和在第三电平是改变的电平的情况下与第二和第三能级之间的过渡谐振的第二相干光束能量级结构，从而改变角度频率在其一轴的平面中的分布，其中第一跃迁角频率相应涉及到第一和第三能级之间的转变，其另一轴是对应于第二和第三能级之间的转变的第二过渡角频率，从而形成具有新的过渡角频率分布的固态材料其中第二步骤包括设置第一光束的光谱宽度的步骤，用于第二光束的转变的Rabi特性角频率和用于第二光束的两个非均匀宽度之一的转变的Rabi特征角频率第一和第二过渡角频率比另一个更宽。

36. 发明授权

US08673595B2 Sample analysis method and assay kit used therein 失效
标题翻译：其中使用的样品分析方法和测定试剂盒
公开(公告)号：US08673595B2
公开(公告)日：2014-03-18
申请号：US13340572
申请日：2011-12-29
申请人： Naoko Nakamura , Koji Hashimoto , Nobuhiro Gemma
发明人： Naoko Nakamura , Koji Hashimoto , Nobuhiro Gemma
IPC分类号： C12P19/34
CPC分类号： C12Q1/6837 , C12Q1/6809 , C12Q1/6853 , C12Q2525/161 , C12Q2525/301 , C12Q2537/143 , C12Q2563/179 , C12Q2565/514
摘要： One embodiment is related to a method of analyzing plural samples. The method includes amplifying a plurality of samples using a first primer and second primer, wherein the first primer includes a tag sequence having a sequence different from a sample to one another and wherein a second primer used in pair with the first primer in independent reaction systems for the respective samples to obtain an amplified product in which the tag sequence is introduced, mixing amplified products obtained in the plurality of reaction systems, making the mixed amplified product react with a nucleic acid probe immobilized on a substrate, and detecting the amount of hybridization that has occurred.
摘要翻译：一个实施例涉及分析多个样本的方法。该方法包括使用第一引物和第二引物扩增多个样品，其中第一引物包含具有不同于样品的序列的标签序列，并且其中与独立反应体系中的第一引物成对配对的第二引物对于各样品获得其中引入标签序列的扩增产物，混合在多个反应体系中获得的扩增产物，使得混合的扩增产物与固定在底物上的核酸探针反应，并检测杂交的量已经发生了。

37. 发明申请

US20100099094A1 METHOD OF DETECTING NUCLEIC ACID AMPLIFICATION REACTION 审中-公开
标题翻译：检测核酸放大反应的方法
公开(公告)号：US20100099094A1
公开(公告)日：2010-04-22
申请号：US12498721
申请日：2009-07-07
申请人： Jun OKADA , Nobuhiro Gemma
发明人： Jun OKADA , Nobuhiro Gemma
IPC分类号： C12Q1/68
CPC分类号： C12Q1/682 , C12Q1/6825 , C12Q2565/607 , C12Q2565/301 , C12Q2563/113
摘要： The present invention provides a method of detecting a nucleic acid amplification reaction, including the steps of adding a sample nucleic acid to a nucleic acid amplification buffer containing a reducing agent molecule, a redox molecule and a magnesium ion, to conduct an amplification reaction, measuring a reduction current produced by a reduction reaction of the reducing agent molecule with the redox molecule, under the conditions that when the amplification reaction of the sample nucleic acid has proceeded in the buffer, pyrophosphoric acid formed with the progress of amplification of the sample nucleic acid forms magnesium pyrophosphate with the magnesium ion, thereby decreasing a magnesium ion concentration of the buffer, and determining, from the magnitude of the reduction current measured above, whether the sample nucleic acid has been amplified or not.
摘要翻译：本发明提供一种检测核酸扩增反应的方法，包括以下步骤：将样品核酸加入到含有还原剂分子，氧化还原分子和镁离子的核酸扩增缓冲液中进行扩增反应，测定在还原剂分子与氧化还原分子的还原反应产生的还原电流在样品核酸的扩增反应在缓冲液中进行的条件下，随着样品核酸的扩增进行而形成的焦磷酸与镁离子形成焦磷酸镁，从而降低缓冲液的镁离子浓度，并根据上述测定的还原电流的大小来确定样品核酸是否已被放大。

38. 发明申请

US20100021907A1 METHOD OF DETECTING A PLURALITY OF NUCLEIC ACIDS 审中-公开
标题翻译：检测多种核酸的方法
公开(公告)号：US20100021907A1
公开(公告)日：2010-01-28
申请号：US12483840
申请日：2009-06-12
申请人： Jun OKADA , Nobuhiro Gemma
发明人： Jun OKADA , Nobuhiro Gemma
IPC分类号： C12Q1/68 , C12M1/34
CPC分类号： C12Q1/6837
摘要： The present invention provides a method of detecting a plurality of nucleic acid samples, includes a first step of preparing a nucleic acid sample detection device, a second step of preparing 1st to nth nucleic acid sample discrimination reagents, a third step of adding the 1st to nth nucleic acid sample discrimination reagents to 1st to nth nucleic acid samples respectively, a fourth step of injecting the 1st to nth nucleic acid samples into 1st to nth wells respectively, a fifth step of detecting the presence or absence of a reaction in positive control immobilization regions in the 1st to nth wells, and a sixth step of detecting the presence or absence of a reaction in detection nucleic acid probe immobilization regions in the 1st to nth wells.
摘要翻译：本发明提供检测多个核酸样品的方法，包括制备核酸样品检测装置的第一步骤，制备第1至第n核酸样品鉴别试剂的第二步骤，将第1步骤添加至第1步骤第n个核酸样品鉴别试剂分别对第1至第n个核酸样品，第4步骤，将第1至第n个核酸样品分别注射到第1至第n个孔中;第五步骤，检测阳性对照固定中存在或不存在反应第1〜第n孔的检测核酸探针固定区域的反应的存在或不存在的第6工序。

39. 发明申请

US20090061433A1 NUCLEOTIDE PRIMER SET AND NUCLEOTIDE PROBE FOR DETECTING GENOTYPE OF SERUM AMYLOID A1(SAA1) 审中-公开
标题翻译：用于检测血清AMYLOID A1（SAA1）基因组的核酸酶基因组和核酸探针
公开(公告)号：US20090061433A1
公开(公告)日：2009-03-05
申请号：US12049475
申请日：2008-03-17
申请人： Naoko NAKAMURA , Keiko Ito , Masayoshi Takahashi , Koji Hashimoto , Nobuhiro Gemma
发明人： Naoko NAKAMURA , Keiko Ito , Masayoshi Takahashi , Koji Hashimoto , Nobuhiro Gemma
IPC分类号： C12Q1/68 , C07H21/04
CPC分类号： C12Q1/6853 , C12Q2531/119 , C12Q2525/155
摘要： Provided is a LAMP-amplification nucleotide primer set for detection of the genotype of single nucleotide polymorphisms C-13T, C2995T and T3010C of the SAA1 gene. Also provided is a nucleotide probe for detection of the amplification product amplified with the primer set according to the present invention. Further provided is a method of detecting the genotype of the single nucleotide polymorphisms C-13T, C2995T and T3010C of the SAA1 gene by using the primer set according to the present invention.
摘要翻译：提供了用于检测SAA1基因的单核苷酸多态性C-13T，C2995T和T3010C的基因型的LAMP扩增核苷酸引物组。还提供了用于检测用根据本发明的引物组扩增的扩增产物的核苷酸探针。进一步提供了通过使用本发明的引物组检测SAA1基因的单核苷酸多态性C-13T，C2995T和T3010C的基因型的方法。

40. 发明申请

US20090053716A1 METHOD OF DETECTING HUMAN CYTOCHROME P450 (CYP) 2D6 GENE MUTATION 审中-公开
标题翻译：检测人细胞色素P450（CYP）2D6基因突变的方法
公开(公告)号：US20090053716A1
公开(公告)日：2009-02-26
申请号：US12175070
申请日：2008-07-17
申请人： Naoko Nakamura , Tsuyoshi Fukuda , Junichi Azuma , Nobuhiro Gemma
发明人： Naoko Nakamura , Tsuyoshi Fukuda , Junichi Azuma , Nobuhiro Gemma
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6876 , C12Q2600/156 , C12Q2600/172
摘要： A defect or multi-existence of a CYP2D6 gene is detected with a primer includes a complementary sequence to a sequence which is common between the CYP2D6 gene and a CYP2D8 gene but different from a CYP2D7 gene and which contains one or more of bases at the 86-, 90- and 93-positions in Exon 9 region of the CYP2D6 gene.
摘要翻译：用引物检测CYP2D6基因的缺陷或多重存在，其包括与CYP2D6基因和CYP2D8基因之间共同但与CYP2D7基因不同但在86位含有一个或多个碱基的序列的互补序列 - ，CYP2D6基因的外显子9区域的90-93位。

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