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31. 发明申请

US20080316020A1 RFID ANTENNA FOR IN-BODY DEVICE 有权
标题翻译： RFID天线用于身体内装置
公开(公告)号：US20080316020A1
公开(公告)日：2008-12-25
申请号：US12126798
申请日：2008-05-23
申请人： TIMOTHY L. ROBERTSON , Olivier Colliou , Eric J. Snyder , Mark J. Zdeblick
发明人： TIMOTHY L. ROBERTSON , Olivier Colliou , Eric J. Snyder , Mark J. Zdeblick
IPC分类号： H04Q7/00
CPC分类号： A61B5/07 , A61B1/00016 , A61B1/041 , H01Q1/2208 , H01Q1/36
摘要： RFID antennas for ingestible devices, such as ingestible event markers, are provided. Aspects of the ingestible devices of the invention include RFID signal transmission antennas with a battery that is activated upon being exposed to fluid in the body. Embodiments of the RFID antennas are configured to emit a detectable signal upon contact with a target physiological site. Also provided are methods of making and using the devices of the invention.
摘要翻译：提供了可摄取装置的RFID天线，例如可摄取事件标记。本发明的可摄取装置的方面包括具有电池的RFID信号传输天线，其在暴露于身体中的流体时被激活。 RFID天线的实施例被配置为在与目标生理部位接触时发出可检测信号。还提供了制造和使用本发明的装置的方法。

32. 发明申请

US20080306360A1 LOW PROFILE ANTENNA FOR IN BODY DEVICE 有权
标题翻译：用于身体装置的低剖面天线
公开(公告)号：US20080306360A1
公开(公告)日：2008-12-11
申请号：US12126792
申请日：2008-05-23
申请人： Timothy L. Robertson , Olivier Colliou , Eric J. Snyder , Mark J. Zdeblick
发明人： Timothy L. Robertson , Olivier Colliou , Eric J. Snyder , Mark J. Zdeblick
IPC分类号： A61B5/07 , H01Q1/36
CPC分类号： A61B5/07 , A61B1/00016 , A61B1/041 , H01Q1/2208 , H01Q1/36
摘要： Low profile antennas for ingestible devices, such as ingestible event markers, are provided. Aspects of the ingestible devices of the invention include low profile signal transmission antennas configured such that they are flexible or degrade after use, allowing the antenna and attached components to pass easily through the body. Embodiments of the low profile antennas are configured to emit a detectable signal upon contact with a target physiological site. Also provided are methods of making and using the devices of the invention.
摘要翻译：提供用于可摄取装置的低轮廓天线，例如可摄取事件标记。本发明的可摄取装置的方面包括配置成在使用后它们是柔性的或降级的低轮廓信号传输天线，允许天线和附接的部件容易地穿过身体。低轮廓天线的实施例被配置为在与目标生理部位接触时发出可检测信号。还提供了制造和使用本发明的装置的方法。

33. 发明申请

US20080306359A1 Medical Diagnostic and Treatment Platform Using Near-Field Wireless Communication of Information Within a Patient's Body 有权
标题翻译：医疗诊断和治疗平台使用病人体内信息的近场无线通信
公开(公告)号：US20080306359A1
公开(公告)日：2008-12-11
申请号：US12063095
申请日：2006-09-01
申请人： Mark J. Zdeblick , Timothy Robertson
发明人： Mark J. Zdeblick , Timothy Robertson
IPC分类号： A61B5/07 , A61B5/0265 , A61N1/362 , A61M37/00 , A61B5/145
CPC分类号： A61B5/0022 , A61B5/0028 , A61B5/0031 , A61B5/01 , A61B5/0215 , A61B5/026 , A61B5/0265 , A61B5/145 , A61B5/14535 , A61B5/415 , A61B5/418 , A61B5/6862 , A61B5/6876 , A61M5/172 , A61N1/37217 , A61N1/37223 , G06F19/00 , H02J50/20 , Y02A90/26
摘要： The present invention provides implantable systems that communicate wirelessly with each other using a unique format that enables devices configurations and applications heretofore not possible. Embodiments of the present invention provide communication apparatuses and methods for exchanging information with implantable medical devices. In some embodiments, two implantable devices communicate with each other using quasi-electrostatic signal transmission in a long wavelength/low frequency electromagnetic band, with the patient's body acting as a conductive medium.
摘要翻译：本发明提供了使用能够使设备配置和应用迄今不可能的唯一格式彼此无线通信的可植入系统。本发明的实施例提供了与可植入医疗装置交换信息的通信装置和方法。在一些实施例中，两个可植入装置通过长波长/低频电磁波带中的准静电信号传输彼此进行通信，患者的身体用作导电介质。

34. 发明申请

US20080242976A1 Electric field tomography 审中-公开
标题翻译：电场断层扫描
公开(公告)号：US20080242976A1
公开(公告)日：2008-10-02
申请号：US11664468
申请日：2007-03-30
申请人： Timothy L. Robertson , Olivier Colliou , Benedict J. Costello , George M. Savage , Todd Thompson , Mark J. Zdeblick
发明人： Timothy L. Robertson , Olivier Colliou , Benedict J. Costello , George M. Savage , Todd Thompson , Mark J. Zdeblick
IPC分类号： A61B5/04
CPC分类号： A61B5/1107 , A61B5/686 , A61B2562/046 , A61N1/056 , A61N1/3627 , A61N1/36514 , A61N1/36578 , A61N1/368 , A61N1/3684 , A61N1/375 , A61N1/3752 , A61N1/3756 , A61N2001/0585
摘要： Methods for evaluating motion of a tissue, such as of a cardiac location, e.g., heart wall, via continuous field tomography are provided. In the subject methods, a continuous field (e.g., an electrical, mechanical, electromechanical, or other field) sensing element is stably associated with the tissue location. A property of the applied continuous field is detected with the sensing element to evaluate movement of the tissue location. Also provided are systems, devices and related compositions for practicing the subject methods. The subject methods and devices find use in a variety of different applications, including cardiac resynchronization therapy.
摘要翻译：提供了通过连续场断层摄影评估诸如心脏位置（例如心脏壁）的组织运动的方法。在主题方法中，连续场（例如，电，机械，机电或其他场）感测元件与组织位置稳定地相关联。使用感测元件检测所施加的连续场的属性，以评估组织位置的运动。还提供了用于实践主题方法的系统，装置和相关组合物。主题方法和设备可用于各种不同的应用，包括心脏再同步治疗。

35. 发明授权

US08956287B2 Patient customized therapeutic regimens 有权
标题翻译：患者定制治疗方案
公开(公告)号：US08956287B2
公开(公告)日：2015-02-17
申请号：US12299303
申请日：2007-05-02
申请人： Mark J. Zdeblick , Andrew Thompson , George M. Savage
发明人： Mark J. Zdeblick , Andrew Thompson , George M. Savage
IPC分类号： G06Q50/00 , A61B5/00 , A61B5/07 , H01M8/02 , G06Q10/00 , G06Q50/22 , G06F19/00 , H04B13/00 , H01M8/00
CPC分类号： G06F19/3456 , A61B5/0002 , A61B5/0028 , A61B5/073 , A61B5/4833 , A61B5/4848 , G06F19/00 , G06F19/34 , G06F19/3418 , G06F19/345 , G06F19/3475 , G06Q10/00 , G06Q50/22 , G16H50/20 , H01M8/02 , H01M2220/10 , H04B13/005 , Y10S128/903 , Y10S128/92
摘要： Methods, systems and compositions that allow for treating a patient according to a patient customized therapeutic regimen are provided. Embodiments of the invention include obtaining dosage administration information from a patient and using the same to tailor a therapeutic regimen for the patient. Embodiments of the invention further include preparing and forwarding to the patient physical pharmaceutical dosages based on the customized therapeutic regimen.
摘要翻译：提供了允许根据患者定制的治疗方案治疗患者的方法，系统和组合物。本发明的实施方案包括从患者获得剂量给药信息并使用它来定制患者的治疗方案。本发明的实施方案还包括基于定制的治疗方案制备并转发患者物理药物剂量。

36. 发明申请

US20130018434A1 Void-Free Implantable Hermetically Sealed Structures 审中-公开
标题翻译：无孔植入式密封结构
公开(公告)号：US20130018434A1
公开(公告)日：2013-01-17
申请号：US13619055
申请日：2012-09-14
申请人： Mark J. Zdeblick , Benedict James Costello , Jeremy Frank , Marc Jensen , Todd Thompson , Mohammed Z. Islam
发明人： Mark J. Zdeblick , Benedict James Costello , Jeremy Frank , Marc Jensen , Todd Thompson , Mohammed Z. Islam
IPC分类号： A61N1/375 , H01R43/00
CPC分类号： A61N1/05 , H01L21/561 , H01L23/3107 , H01L24/63 , H01L2924/01005 , H01L2924/01006 , H01L2924/01013 , H01L2924/01024 , H01L2924/01033 , H01L2924/01044 , H01L2924/01045 , H01L2924/01047 , H01L2924/01049 , H01L2924/01074 , H01L2924/01076 , H01L2924/01077 , H01L2924/01078 , H01L2924/01079 , H01L2924/01082 , H01L2924/10253 , H01L2924/12042 , H01L2924/14 , H01L2924/1461 , H01L2924/15787 , Y10T29/49117 , H01L2924/00
摘要： An implantable integrated circuit structure comprising a conformal thin-film sealing layer for hermetically sealing circuitry layers is provided. Also disclosed are electrode structures, leads that include the same, implantable pulse generators that include the leads, as well as systems and kits having components thereof, other implantable devices utilizing the structures, and methods of making and using the subject structures.
摘要翻译：提供了一种包括用于密封电路层的保形薄膜密封层的可植入集成电路结构。还公开了电极结构，包括相同的引线，包括引线的可植入脉冲发生器，以及具有其部件的系统和套件，利用该结构的其它可植入装置，以及制造和使用受试结构的方法。

37. 发明授权

US08258962B2 Multi-mode communication ingestible event markers and systems, and methods of using the same 有权
标题翻译：多模式通信可摄取事件标记和系统及其使用方法
公开(公告)号：US08258962B2
公开(公告)日：2012-09-04
申请号：US12398941
申请日：2009-03-05
申请人： Timothy Robertson , Mark J. Zdeblick
发明人： Timothy Robertson , Mark J. Zdeblick
IPC分类号： G08B23/00
CPC分类号： H04B5/0062 , A61B5/0031 , A61B5/073 , A61B5/4833 , A61B5/4839 , A61B5/4848 , A61B5/6861 , A61B2562/08 , A61B2562/162 , G06K7/10297
摘要： Aspects of the invention include multi-mode communication ingestible event marker devices. Ingestible event marker devices of the invention include an ingestible component comprising a conductive communication module and at least one additional non-conductive communication module. The non-conductive communication module may be integrated with the ingestible component or at least a portion or all of the non-conductive communication module may be associated with a packaging component of the ingestible event marker device. Additional aspects of the invention include systems that include the devices and one or more receivers, as well as methods of using the same.
摘要翻译：本发明的方面包括多模式通信可摄取事件标记装置。本发明的可摄入事件标记装置包括可摄入组件，其包括导电通信模块和至少一个附加的非导电通信模块。非导电通信模块可以与可摄取组件集成，或者非导电通信模块的至少一部分或全部可以与可摄入事件标记设备的包装组件相关联。本发明的另外的方面包括包括装置和一个或多个接收器的系统，以及使用该装置的方法。

38. 发明申请

US20120220838A1 System for Supply Chain Management 有权
标题翻译：供应链管理系统
公开(公告)号：US20120220838A1
公开(公告)日：2012-08-30
申请号：US13508327
申请日：2010-11-04
申请人： Mark J. Zdeblick
发明人： Mark J. Zdeblick
IPC分类号： A61B5/07
CPC分类号： H04B5/0012 , A61B5/061 , G06K7/01 , G06Q10/06
摘要： A system for tracking a product from origin to destination is disclosed. The system includes a probe that comprises two plates, a power source and a processor. The power source is controlled by the processor to produce an oscillating output at the plates. Using the oscillating voltage, the probe interrogates a device through capacitive coupling. The device includes a control unit, a memory unit, and first and second materials physically associated with the device for communication using capacitive coupling. Information associated with the device is transferred from the device to the probe through capacitive coupling between the first and second materials and the first and second plates, respectively.
摘要翻译：公开了一种从原产地到目的地跟踪产品的系统。该系统包括一个包括两个板，一个电源和一个处理器的探头。电源由处理器控制，以在板上产生振荡输出。使用振荡电压，探头通过电容耦合来询问器件。该装置包括控制单元，存储器单元以及物理上与用于使用电容耦合进行通信的装置相关联的第一和第二材料。与装置相关的信息通过第一和第二材料与第一和第二板之间的电容耦合从装置传送到探针。

39. 发明授权

US08195308B2 Implantable hermetically sealed structures 有权
标题翻译：可植入密封结构
公开(公告)号：US08195308B2
公开(公告)日：2012-06-05
申请号：US11794016
申请日：2005-12-22
申请人： Jeremy Frank , Vladimier Gelfandbein , Marc Jensen , Mark J. Zdeblick , Benedict James Costello
发明人： Jeremy Frank , Vladimier Gelfandbein , Marc Jensen , Mark J. Zdeblick , Benedict James Costello
IPC分类号： A61N1/05
CPC分类号： A61N1/375 , A61N1/05 , A61N1/37205 , A61N1/3756
摘要： Implantable hermetically sealed structures and methods for making the same. Devices, systems and kits including the hermetically sealed structures, as well as methods of using such devices and systems are included.
摘要翻译：可植入的密封结构及其制造方法。还包括包括密封结构在内的装置，系统和试剂盒以及使用这些装置和系统的方法。

40. 发明授权

US07983751B2 Measuring conduction velocity using one or more satellite devices 有权
标题翻译：使用一个或多个卫星设备测量传导速度
公开(公告)号：US07983751B2
公开(公告)日：2011-07-19
申请号：US12063097
申请日：2006-08-09
申请人： Mark J. Zdeblick , Timothy Robertson , George M. Savage
发明人： Mark J. Zdeblick , Timothy Robertson , George M. Savage
IPC分类号： A61N1/00
CPC分类号： A61B5/04011
摘要： A method for measuring the conduction velocity of a depolarization wave in a tissue employs a first satellite located within the tissue and a second that satellite is located within the tissue a distance away from the first satellite, e.g., by using the time of depolarization wave as reported from each satellite and the distance to determine velocity of the wave. Also provided are systems and kits that find use in accordance with the invention.
摘要翻译：用于测量组织中去极化波的传导速度的方法使用位于组织内的第一卫星，并且第二卫星位于组织内距离第一卫星一定距离，例如通过使用去极化波的时间作为报道从每颗卫星和距离来确定波的速度。还提供了根据本发明使用的系统和试剂盒。

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