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31. 发明授权

US07481470B2 Integrated tilt/sash lock assembly 有权
标题翻译：集成倾斜/窗扇锁组件
公开(公告)号：US07481470B2
公开(公告)日：2009-01-27
申请号：US11274753
申请日：2005-11-15
申请人： Mark B. Eenigenburg , Dean Pettit , Mark V. Murphy
发明人： Mark B. Eenigenburg , Dean Pettit , Mark V. Murphy
IPC分类号： E05C3/04 , E05C1/10
CPC分类号： E05B5/003 , E05B53/003 , E05B63/06 , E05B65/0841 , E05B65/0876 , E05C1/14 , E05C3/046 , E05C9/00 , E05C9/025 , E05C9/04 , E05C2007/007 , E05D15/22 , E05Y2900/148 , Y10S292/20 , Y10S292/47 , Y10T292/0806 , Y10T292/0839 , Y10T292/0841 , Y10T292/0963 , Y10T292/0997 , Y10T292/1015 , Y10T292/1017 , Y10T292/102 , Y10T292/1041 , Y10T292/1075
摘要： An integrated sash lock and tilt latch assembly for a sash window slidable within a master frame, including a handle movable among a first, a second and a third position to adjust the assembly among a respective locked, unlocked and tiltable position. The integrated assembly further comprises a rotor coupled to the handle and having a locking cam. The integrated assembly also includes a keeper adapted to be connected to an upper sash window. The integrated assembly further includes a latch bolt housing having a latch bolt slidably disposed therein and a spring for biasing the latch bolt towards the master frame. The integrated assembly further includes a connector coupled proximate a first end to the latch bolt and operably coupled proximate a second end to the rotor.
摘要翻译：一种用于可在主框架内滑动的窗框窗口的集成的窗框锁和倾斜闩锁组件，包括可在第一，第二和第三位置之间移动的手柄，以在相应的锁定，解锁和可倾斜位置之间调整组件。集成组件还包括联接到手柄并具有锁定凸轮的转子。集成组件还包括适于连接到上窗扇的保持器。集成组件还包括闩锁螺栓壳体，其具有可滑动地设置在其中的闩锁螺栓和用于将闩锁螺栓朝向主框架偏压的弹簧。集成组件还包括连接到靠近第一端到闩锁螺栓并且可靠地靠近第二端连接到转子的连接器。

32. 发明申请

US20070234642A1 Window Operator Having Seal 审中-公开
标题翻译：窗口操作员有密封
公开(公告)号：US20070234642A1
公开(公告)日：2007-10-11
申请号：US11697506
申请日：2007-04-06
申请人： Richard L. Bildahl , Dean Pettit , Thomas J. Hansel
发明人： Richard L. Bildahl , Dean Pettit , Thomas J. Hansel
IPC分类号： E05F11/24
CPC分类号： E05F11/24
摘要： A casement window assembly has a sash window pivotally connected to a window frame. A window operator has a housing connected to the frame, including an upper and lower piece connected together. The housing has an offset countersink hole receiving a fastener. A spindle extends into the housing and has a groove therein. An arm is operably connected to the spindle and to the sash window to open and close the sash window. A resilient seal member is received within the groove in the spindle. A first gasket is positioned between the upper piece and the lower piece of the housing. A second gasket is positioned between the housing and the window frame. When the fastener is driven into the countersink hole, the housing is forced in a generally horizontal direction to compress the second gasket between the housing and the window frame.
摘要翻译：平开窗组件具有枢转地连接到窗框的窗框窗口。窗户操作者具有连接到框架的壳体，包括连接在一起的上部和下部件。壳体具有接收紧固件的偏移锪孔。心轴延伸到壳体中并且在其中具有凹槽。臂可操作地连接到主轴和窗框窗口以打开和关闭窗扇。弹性密封件容纳在主轴的槽内。第一垫圈位于壳体的上部件和下部件之间。第二垫圈位于壳体和窗框之间。当紧固件被驱动到埋头孔中时，壳体被迫在大致水平的方向上以压缩壳体和窗框之间的第二垫圈。

33. 发明申请

US20070048837A1 Site specific protein modification 审中-公开
标题翻译：位点特异性蛋白质修饰
公开(公告)号：US20070048837A1
公开(公告)日：2007-03-01
申请号：US11588655
申请日：2006-10-26
申请人： Dean Pettit
发明人： Dean Pettit
IPC分类号： C12P21/06 , C07H21/04 , C07K14/715 , C08G63/91
CPC分类号： C07K1/1077 , A61K47/60 , A61K47/62 , C07K14/7151
摘要： Processes for conjugating proteins with polyethylene glycol are disclosed. The disclosed processes provide modified proteins having little or no decrease in their activity and include the steps of deleting at least one amino acid residue on the protein, replacing the at least one amino acid residue with an amino acid residue that does not react with polyethylene glycol, and contacting the protein with polyethylene glycol under conditions sufficient to conjugate the polyethylene glycol to the protein. This advantageous retention of a desired protein activity is attributed to the availability of one or more protein binding sites which is unaltered in the conjugation process and thus remains free to interact with a binding partner ligand or cognate subsequent to the conjugation process.
摘要翻译：公开了将蛋白质与聚乙二醇缀合的方法。所公开的方法提供了其活性几乎没有或没有降低的修饰的蛋白质，包括删除蛋白质上的至少一个氨基酸残基的步骤，用不与聚乙二醇反应的氨基酸残基取代至少一个氨基酸残基并在足以将聚乙二醇与蛋白质缀合的条件下使蛋白与聚乙二醇接触。所需蛋白质活性的这种有利的保留归因于在缀合过程中未改变的一个或多个蛋白质结合位点的可用性，因此在缀合过程之后保持与结合配偶体配体或同源物相互作用。

34. 发明授权

US07013603B2 Integrated tilt/sash lock assembly 有权
公开(公告)号：US07013603B2
公开(公告)日：2006-03-21
申请号：US10289803
申请日：2002-11-07
申请人： Mark B. Eenigenburg , Dean Pettit , Aaron Eiger , Scott Rote , Scott Zeeb
发明人： Mark B. Eenigenburg , Dean Pettit , Aaron Eiger , Scott Rote , Scott Zeeb
IPC分类号： E05D15/22
CPC分类号： E05B5/003 , E05B53/003 , E05B63/06 , E05B65/0841 , E05B65/0876 , E05C1/14 , E05C3/046 , E05C9/00 , E05C9/025 , E05C9/04 , E05C2007/007 , E05D15/22 , E05Y2900/148 , Y10S292/20 , Y10S292/47 , Y10T292/0806 , Y10T292/0839 , Y10T292/0841 , Y10T292/0963 , Y10T292/0997 , Y10T292/1015 , Y10T292/1017 , Y10T292/102 , Y10T292/1041 , Y10T292/1075
摘要： An integrated tilt/sash lock assembly for a sash window is disclosed. The sash window assembly has an upper sash window and a lower sash window slideable within a master frame, the integrated assembly has a keeper adapted to be connected to the upper sash window. A rotor assembly is adapted to be supported by the lower sash window, the rotor assembly having a rotor connected to a spool. A latch bolt is adapted to be supported by the lower sash window and is adapted to engage the master frame. A connector has a first end connected to the spool and a second end connected to the latch bolt. An actuator is connected to the rotor assembly. The actuator has a locked position wherein the rotor engages the keeper. The actuator is moveable to an unlocked position wherein the rotor assembly is disengaged from the keeper, and is further moveable to a tiltable position wherein the connector retracts the latch bolt from the master frame.

35. 发明授权

US07013529B2 Block and tackle sash balance brake assembly 失效
公开(公告)号：US07013529B2
公开(公告)日：2006-03-21
申请号：US10277258
申请日：2002-10-22
申请人： Dean Pettit , Mark Eenigenburg
发明人： Dean Pettit , Mark Eenigenburg
IPC分类号： E05D15/22
CPC分类号： E05D15/22 , E05D13/1207 , E05Y2900/148 , Y10T16/6298 , Y10T16/64 , Y10T16/82
摘要： A block and tackle sash balance assembly for providing a counterbalancing force to a sash window pivotally and slideably mounted within a sash window frame is disclosed. The assembly is adapted to disable the counterbalancing force responsive to pivoting of the sash window.

36. 发明申请

US20060057103A1 Antagonists of interleukin-15 失效
标题翻译：白细胞介素15的拮抗剂
公开(公告)号：US20060057103A1
公开(公告)日：2006-03-16
申请号：US11221399
申请日：2005-09-07
申请人： Kenneth Grabstein , Dean Pettit , Raymond Paxton
发明人： Kenneth Grabstein , Dean Pettit , Raymond Paxton
IPC分类号： A61K39/395 , C07K14/54 , A61K38/20
CPC分类号： C07K16/244 , A61K38/00 , A61K47/60 , C07K14/5443 , C07K2317/76
摘要： Antagonists of mammalian interleukin-15 (“IL-15”) are disclosed and include muteins of IL-15 and modified IL-15 molecules that are each capable of binding to the IL-15Rα-subunit and that are incapable of transducing a signal through either the β- or γ-subunits of the IL-15 receptor complex. Also included are monoclonal antibodies against IL-15 that prevent IL-15 from effecting signal transduction through either the β- or γ-subunits of the IL-15 receptor complex. Methods of treating various disease states are disclosed, including treating allograft rejection and graft-versus-host disease,
摘要翻译：公开了哺乳动物白细胞介素-15（“IL-15”）的拮抗剂，并且包括IL-15和修饰的IL-15分子的突变蛋白，其各自能够结合IL-15Rα-亚基并且不能通过 IL-15受体复合物的β亚基或γ亚基。还包括针对IL-15的单克隆抗体，其阻止IL-15通过IL-15受体复合物的β亚基或γ亚基进行信号转导。公开了治疗各种疾病状态的方法，包括治疗同种异体移植排斥和移植物抗宿主病，

37. 发明申请

US20050235586A1 Clip and sash assembly for mounting components between glazing panes 有权
标题翻译：夹具和窗框组件，用于在玻璃窗之间安装组件
公开(公告)号：US20050235586A1
公开(公告)日：2005-10-27
申请号：US11138957
申请日：2005-05-25
申请人： Robert Hornung , John France , Mark Murphy , Dean Pettit , Rodney Erdman
发明人： Robert Hornung , John France , Mark Murphy , Dean Pettit , Rodney Erdman
IPC分类号： B26F1/02 , E04C2/54 , E06B3/24 , E06B3/64 , E06B3/66 , E06B3/663 , E06B3/667 , E06B3/70 , E06B3/964 , F16B20060101 , F16B1/00
CPC分类号： E06B3/6675 , E06B3/24 , E06B3/64 , E06B3/6604 , E06B3/667
摘要： Techniques are provided for mounting simulated muntin bars, preassembled muntin grids and the like between parallel glazing sheets in an integrated multipane window sash. Among the mounting techniques disclosed are clips for holding simulated muntin components to a spacing and mounting structure of an integrated multipane window sash. Clip-less embodiments are also presented, as well as a one-piece sash that includes integral muntins and an integral spacing and mounting structure for the glazing sheets.
摘要翻译：提供了一种技术，用于在整合的多窗口窗扇中的平行玻璃板之间安装模拟的木板，预组装的木地板等。所公开的安装技术中的夹具是用于将模拟的模块组件保持为集成的多窗户窗扇的间隔和安装结构。还提出了无剪切实施例，以及包括整体式的单片式窗框和用于玻璃板的整体间隔和安装结构。

38. 发明申请

US20050016067A1 Integrated tilt/sash lock assembly 有权
标题翻译：集成倾斜/窗扇锁组件
公开(公告)号：US20050016067A1
公开(公告)日：2005-01-27
申请号：US10863089
申请日：2004-06-08
申请人： Dean Pettit , Mark Eenigenburg
发明人： Dean Pettit , Mark Eenigenburg
IPC分类号： E05B53/00 , E05B63/06 , E05B65/08 , E05C1/14 , E05C3/04 , E05C9/02 , E05D15/22
CPC分类号： E05C1/14 , E05B5/003 , E05B53/003 , E05B63/06 , E05B65/0841 , E05B65/0876 , E05C3/046 , E05C9/00 , E05C9/02 , E05C9/021 , E05C9/04 , E05C9/041 , E05C9/10 , E05C2007/007 , E05D15/22 , E05Y2900/148 , Y10S292/20 , Y10S292/47
摘要： An integrated tilt/sash lock assembly for a sash window is disclosed. The sash window assembly has an upper sash window and a lower sash window slideable within a master frame, the integrated assembly has a keeper adapted to be connected to the upper sash window. A rotor assembly is adapted to be supported by the lower sash window, the rotor assembly having a rotor connected to a spool. A latch bolt is adapted to be supported by the lower sash window and is adapted to engage the master frame. A connector has a first end connected to the spool and a second end connected to the latch bolt. An actuator is connected to the rotor assembly. The actuator has a locked position wherein the rotor engages the keeper. The actuator is moveable to an unlocked position wherein the rotor assembly is disengaged from the keeper, and is further moveable to a tiltable position wherein the connector retracts the latch bolt from the master frame.
摘要翻译：公开了一种用于窗扇的集成的倾斜/窗扇锁组件。窗框组件具有可在主框架内滑动的上窗框和下窗框，该集成组件具有适于连接到上窗扇的保持件。转子组件适于由下窗扇支撑，转子组件具有连接到卷轴的转子。闩锁螺栓适于由下窗扇支撑并且适于接合主框架。连接器具有连接到卷轴的第一端和连接到闩锁螺栓的第二端。致动器连接到转子组件。致动器具有锁定位置，其中转子接合保持器。致动器可移动到解锁位置，其中转子组件与保持器脱离，并且还可移动到可倾斜的位置，其中连接器将锁闩从主框架缩回。

39. 发明授权

US06568723B2 Sash lock for a sash window 失效
公开(公告)号：US06568723B2
公开(公告)日：2003-05-27
申请号：US09961501
申请日：2001-09-24
申请人： Mark V. Murphy , Dean Pettit
发明人： Mark V. Murphy , Dean Pettit
IPC分类号： E05C304
CPC分类号： E05B65/0835 , E05B15/1635 , E05B2015/1664 , E05B2015/1671 , E05C3/046 , E05C2007/007 , Y10S292/07 , Y10S292/38 , Y10S292/47 , Y10T292/1041
摘要： A sash lock for a sash window assembly is disclosed. The sash window assembly includes an upper sash window and a lower sash window. Each of the sash windows is mounted within opposed guide rails on a master frame. At least one of the sash windows is slidable within the frame relative to the other sash window. The sash lock comprises a keeper for mounting on a style of one of the sash windows. The keeper includes a keeper surface. The sash lock also includes a locking assembly for mounting on an adjacent style of the other of the sash windows. The locking assembly includes a housing having a hole, an actuator arm, and a cam having a cam surface for engaging the keeper surface. The locking assembly also includes a shaft extending through the housing hole and operably coupling the actuator arm to the cam. The keeper, the housing, the actuator arm and the shaft are formed of plastic and the cam is formed of metal.

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