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    • 34. 发明授权
    • Arrangement for attaining high-precision measurements of an eye
    • 用于获得眼睛高精度测量的布置
    • US08491122B2
    • 2013-07-23
    • US13091836
    • 2011-04-21
    • Martin HackerScott A. Meyer
    • Martin HackerScott A. Meyer
    • A61B3/14
    • A61B3/152
    • A solution for attaining high-precision and reproducible measurements during opthalmological biometry and imaging includes an illumination unit for producing a fixation marker, a device for transmitting the light of the produced fixation marker into the eye, a measurement device and a control unit. The illumination unit includes a device for the targeted change of the beam direction of the produced fixation marker. A camera for the detection of the line of vision of the eye is connected to the control unit. The control unit determines the sufficient congruity between detected line of vision and displayed beam direction of the produced fixation marker and, in dependence of the degree of probability of the congruity, triggers a measurement. The suggested arrangement is applicable for opthalmological diagnostic devices, which exhibit a camera and a measuring system, whereby measurements can be taken in all areas of the eye.
    • 用于在眼科生物测定和成像期间获得高精度和可再现的测量的解决方案包括用于产生固定标记的照明单元,用于将产生的定影标记的光透射到眼睛中的装置,测量装置和控制单元。 照明单元包括用于靶向改变所产生的定影标记的光束方向的装置。 用于检测眼睛视线的相机连接到控制单元。 控制单元确定检测到的视线与所产生的固定标记的显示光束方向之间的足够的一致性,并且根据一致性概率的程度触发测量。 该建议的布置适用于展示相机和测量系统的眼科诊断装置,由此可以在眼睛的所有区域进行测量。
    • 39. 发明授权
    • RNFL measurement analysis
    • RNFL测量分析
    • US08128229B2
    • 2012-03-06
    • US12859727
    • 2010-08-19
    • Scott A. MeyerMary K. DurbinPaul F. StetsonBagrat Amirbekian
    • Scott A. MeyerMary K. DurbinPaul F. StetsonBagrat Amirbekian
    • A61B3/10
    • A61B3/12A61B3/1241
    • One embodiment of the present invention accounts for individual anatomical variation when evaluating optical nerve fiber measurements. In one aspect, contextual information is used to compensate or correct measurement data. In another aspect, reference coordinates are remapped for improved comparison or visualization. In one embodiment of this latter aspect, the method uses measurements of nerve fiber capacity and maps of nerve fiber retinal service to improve sensitivity and specificity in eye function metrics. In one instance, we use the birefringence of nerve fibers to determine the orientation of the fibers within the RNFL. Orientation of the fibers about the ONH is indicative of the service provided by the fibers and is used to improve the interpretation of thickness measurements of the nerve fiber layer. Normalized nerve fiber measurements about the optic nerve head improve specificity and sensitivity as compared to the standard model. These improvements are a result of partitioning the normative database or modifying the measurement data prior to comparison. Statistics on normalized measurements of nerve fiber bundles also show improvements in specificity and sensitivity.
    • 评估光学神经纤维测量时,本发明的一个实施例解释了个体解剖学变化。 在一个方面,使用上下文信息来补偿或校正测量数据。 在另一方面,重新映射参考坐标以改善比较或可视化。 在后一方面的一个实施例中,该方法使用神经纤维能力的测量和神经纤维视网膜服务的图来提高眼睛功能度量中的灵敏度和特异性。 在一种情况下,我们使用神经纤维的双折射来确定RNFL内纤维的取向。 关于ONH的纤维的取向指示由纤维提供的服务,并且用于改善对神经纤维层的厚度测量的解释。 与标准模型相比,关于视神经头的规范化神经纤维测量提高了特异性和灵敏度。 这些改进是在比较之前划分规范性数据库或修改测量数据的结果。 关于神经纤维束的归一化测量的统计数据也显示出特异性和灵敏度的改善。