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31. 发明授权

US07704248B2 Ablation device with compression balloon 有权
标题翻译：消融装置与压缩气球
公开(公告)号：US07704248B2
公开(公告)日：2010-04-27
申请号：US11315426
申请日：2005-12-21
申请人： Paul DiCarlo
发明人： Paul DiCarlo
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B2018/0016 , A61B2018/00285 , A61B2018/143 , A61B2018/1432
摘要： A tissue ablation device includes an array of elongate electrodes configured to be deployed in tissue, wherein the deployed electrode array defines a tissue ablation region, an inflatable balloon configured to be deployed in tissue, and a coupler securing the balloon relative to the one or more elongate electrodes, wherein the balloon, when inflated, is configured to apply a force to tissue located in the tissue ablation region. An ablation device includes a first array of electrodes, a second array of electrodes, a first inflatable balloon, and a coupler securing the first balloon relative to the first and second electrode arrays. A method of ablating tissue includes positioning an array of elongate electrodes and an inflatable balloon proximate tissue to be ablated, inflating the balloon to compress a tissue region located between the balloon and the electrode array, and energizing the electrode array to ablate the tissue region.
摘要翻译：组织消融装置包括构造成部署在组织中的细长电极的阵列，其中所展开的电极阵列限定组织消融区域，构造成部署在组织中的可充气气囊，以及将球囊相对于一个或多个细长电极，其中所述气囊在充气时被配置为向位于所述组织消融区域中的组织施加力。消融装置包括第一电极阵列，第二电极阵列，第一可充气气囊和联接器，其相对于第一和第二电极阵列固定第一球囊。消融组织的方法包括将细长电极阵列和靠近要消融的组织的可充气球囊定位，使球囊膨胀以压缩位于球囊和电极阵列之间的组织区域，以及激励电极阵列以消融组织区域。

32. 发明申请

US20090068271A1 EMBOLIZATION PARTICLES 审中-公开
标题翻译：嵌合颗粒
公开(公告)号：US20090068271A1
公开(公告)日：2009-03-12
申请号：US12179115
申请日：2008-07-24
申请人： Paul DiCarlo , Barron W. Tenney , Yixin Xu , Michael N. Helmus
发明人： Paul DiCarlo , Barron W. Tenney , Yixin Xu , Michael N. Helmus
IPC分类号： A61K9/14 , B32B15/02 , B32B27/02
CPC分类号： A61K9/1635 , A61K9/146 , Y10T428/2933 , Y10T428/2935 , Y10T428/2936 , Y10T428/294 , Y10T428/298
摘要： Embolic particles, embolic particle chains, and methods for making embolic particles and embolic particle chains are described.
摘要翻译：描述了栓塞颗粒，栓塞颗粒链和制备栓塞颗粒和栓塞颗粒链的方法。

33. 发明授权

US07238184B2 Ablation probe with peltier effect thermal control 有权
标题翻译：消融探头与珀耳帖效应热控制
公开(公告)号：US07238184B2
公开(公告)日：2007-07-03
申请号：US10802092
申请日：2004-03-15
申请人： Joseph Megerman , Paul DiCarlo
发明人： Joseph Megerman , Paul DiCarlo
IPC分类号： A61B18/14 , A61B18/02
CPC分类号： A61B18/02 , A61B18/1477 , A61B2018/0237 , A61B2018/0243 , A61B2018/087 , A61B2018/143 , A61B2018/1432
摘要： A tissue ablation probe, system, and method are provided. The ablation probe comprises an elongated member, an ablative element mounted on the distal end of the elongated member, and at least one thermoelectric device mounted to the member in thermal communication with the ablative element. The system may include the ablation probe, thermal control circuitry for controlling the thermal effect of the thermoelectric device, and an ablation source for suppying ablation energy to the ablative element. A plurality of circumferentially distributed thermoelectric devices can be provided, so that radial tissue sectors can be selectively affected by independently controlling the thermal effect of the thermoelectric devices. In one embodiment, the thermoelectric device(s) can be used to cool a heat ablative element. In another embodiment, the thermoelectric device(s) can be used to heat an ablative element, thereby forming a heat ablative element. In still another embodiment, the thermoelectric device(s) can be used to cryogenically cool an ablative element, thereby forming a cryogenic ablative element.
摘要翻译：提供组织消融探针，系统和方法。消融探针包括细长构件，安装在细长构件的远端上的消融元件以及安装到与烧蚀元件热连通的构件的至少一个热电装置。该系统可以包括消融探针，用于控制热电装置的热效应的热控制电路，以及用于将烧蚀能量用于烧蚀元件的消融源。可以提供多个周向分布的热电装置，使得可以通过独立地控制热电装置的热效应来选择性地影响径向组织扇区。在一个实施例中，热电装置可以用于冷却热消融元件。在另一个实施例中，热电装置可用于加热烧蚀元件，从而形成热消融元件。在另一个实施例中，热电装置可用于低温冷却烧蚀元件，从而形成低温烧蚀元件。

34. 发明申请

US20070142830A1 Ablation device with compression balloon 有权
标题翻译：消融装置与压缩气球
公开(公告)号：US20070142830A1
公开(公告)日：2007-06-21
申请号：US11315426
申请日：2005-12-21
申请人： Paul DiCarlo
发明人： Paul DiCarlo
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B2018/0016 , A61B2018/00285 , A61B2018/143 , A61B2018/1432
摘要： A tissue ablation device includes an array of elongate electrodes configured to be deployed in tissue, wherein the deployed electrode array defines a tissue ablation region, an inflatable balloon configured to be deployed in tissue, and a coupler securing the balloon relative to the one or more elongate electrodes, wherein the balloon, when inflated, is configured to apply a force to tissue located in the tissue ablation region. An ablation device includes a first array of electrodes, a second array of electrodes, a first inflatable balloon, and a coupler securing the first balloon relative to the first and second electrode arrays. A method of ablating tissue includes positioning an array of elongate electrodes and an inflatable balloon proximate tissue to be ablated, inflating the balloon to compress a tissue region located between the balloon and the electrode array, and energizing the electrode array to ablate the tissue region.
摘要翻译：组织消融装置包括构造成部署在组织中的细长电极的阵列，其中所展开的电极阵列限定组织消融区域，构造成部署在组织中的可充气气囊，以及将球囊相对于一个或多个细长电极，其中所述气囊在充气时被配置为向位于所述组织消融区域中的组织施加力。消融装置包括第一电极阵列，第二电极阵列，第一可充气气囊和联接器，其相对于第一和第二电极阵列固定第一球囊。消融组织的方法包括将细长电极阵列和靠近要消融的组织的可充气球囊定位，使球囊膨胀以压缩位于球囊和电极阵列之间的组织区域，以及激励电极阵列以消融组织区域。

35. 发明申请

US20070135709A1 Radiation ablation tracking system and method 失效
标题翻译：辐射消融跟踪系统及方法
公开(公告)号：US20070135709A1
公开(公告)日：2007-06-14
申请号：US11298807
申请日：2005-12-09
申请人： Robert Rioux , Paul DiCarlo
发明人： Robert Rioux , Paul DiCarlo
IPC分类号： A61B5/05
CPC分类号： A61N5/1049 , A61B18/1477 , A61B18/148 , A61B2018/1425 , A61B2018/143 , A61B2018/1432 , A61N5/1065 , A61N2005/1061
摘要： A system and method for treating a target tissue region (e.g., malignant tissue) is provided. A hyperthermic probe is placed into contact with the target tissue region, and the target tissue region is exposed to a therapeutic x-ray radiation beam. The probe is operated to increase the temperature of the target tissue region, thereby facilitating a therapeutic effect of the radiation beam. Image data of the probe containing a fiducial datum is acquired while in contact with the target tissue region, a position of the target tissue region within a treatment coordinate system is determined based on the fiducial datum, and the radiation beam is spatially adjusted relative to the target tissue region based on the determined position of the target tissue region.
摘要翻译：提供了用于治疗靶组织区域（例如，恶性组织）的系统和方法。将高温探针放置成与目标组织区域接触，并且将目标组织区域暴露于治疗性X射线辐射束。操作探针以增加靶组织区域的温度，从而有助于辐射束的治疗效果。在与目标组织区域接触的同时获取包含基准数据的探针的图像数据，基于基准原理确定处理坐标系内的目标组织区域的位置，并且相对于基于所确定的目标组织区域的位置的目标组织区域。

36. 发明申请

US20060200120A1 Apparatus for switching nominal and attenuated power between ablation probes 失效
公开(公告)号：US20060200120A1
公开(公告)日：2006-09-07
申请号：US11073917
申请日：2005-03-07
申请人： Paul DiCarlo , Robert Rioux
发明人： Paul DiCarlo , Robert Rioux
IPC分类号： A61B18/14
CPC分类号： A61B18/14 , A61B18/1206 , A61B18/1477 , A61B2018/124 , A61B2018/1273 , A61B2018/1425 , A61B2560/0214
摘要： A tissue ablation system comprises an ablation source, such as an RF ablation source, configured for generating a common power signal, and a power multiplexor configured for splitting the power signal into first and second power signals, substantially attenuating the second power signal relative to the first power signal to create nominal and attenuated power signals, and sequentially delivering the nominal power signal to each tissue ablation probe, while delivering the attenuated power signal to the remaining ablation probes to which the nominal power signal is currently not delivered.

37. 发明授权

US06994722B2 Implant having improved fixation to a body lumen and method for implanting the same 失效
公开(公告)号：US06994722B2
公开(公告)日：2006-02-07
申请号：US09898936
申请日：2001-07-03
申请人： Paul DiCarlo
发明人： Paul DiCarlo
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2/90 , A61F2002/075 , A61F2230/0054
摘要： A device for improving fixation and sealing of a prosthetic component when implanted in a body lumen during laparoscopic, endovascular, or open surgical procedures. In one embodiment, the prosthetic component comprises a graft having a hem defining an interior space. Enclosed within the space is an absorbent cord. The cord expands as it comes in contact with body fluids. The expansion due to the absorbed fluids forms a seal closely following the irregular shape of the lumen and improves fixation at the junction of the body lumen and the prosthetic component. Hem and cord arrangement also used to improve fixation of one prosthetic component to another in a modular graft. In another embodiment, an attachment tab has one part affixed to the outer periphery of the graft and another part attached to an area adjacent to the body lumen upon implantation, to resist forces tending to move the implant.

38. 发明授权

US06929626B2 Intraluminally placeable textile catheter, drain and stent 失效
标题翻译：腔内可放置纺织导管，排水管和支架
公开(公告)号：US06929626B2
公开(公告)日：2005-08-16
申请号：US10342950
申请日：2003-01-15
申请人： Paul DiCarlo , Christopher J. Elliott , William J. Shaw , Brett Haarala
发明人： Paul DiCarlo , Christopher J. Elliott , William J. Shaw , Brett Haarala
IPC分类号： A61F2/04 , A61F2/90 , A61L29/08 , A61L31/10 , A61M25/00 , A61M5/00
CPC分类号： A61L31/10 , A61F2/90 , A61F2002/048 , A61L29/085 , A61M25/0043
摘要： An intraluminally placeable tubular device includes an elongate hollow tubular member having a luminal surface and an exterior surface defining a wall portion therebetween. The hollow tubular member has an open proximal end and an opposed distal end. The wall portion has sufficient self-supporting rigidity to permit the device to be advanced through a body lumen during intraluminal placement. The tubular member includes yarns interconnected in a pattern defining opposed interior and exterior textile surfaces. At least one of the textile surfaces is the body fluid-contacting luminal surface or the body lumen-contacting exterior surface. A textile infusion and/or a textile aspiration valve is also provided. A percutaneously or orificially placeable catheter with such textile valves is provided.
摘要翻译：腔内可置放管状装置包括细长的中空管状构件，其具有腔表面和限定其间的壁部分的外表面。中空管状构件具有敞开的近端和相对的远端。壁部分具有足够的自支撑刚度，以允许装置在腔内放置期间通过体腔前进。管状构件包括以限定相对的内部和外部织物表面的图案互连的纱线。织物表面中的至少一个是与体液接触的腔表面或体腔内接触的外表面。还提供纺织品输液和/或织物抽吸阀。提供具有这种织物阀的经皮或人造可放置的导管。

39. 发明授权

US06607504B2 Percutaneous access 有权
标题翻译：经皮进入
公开(公告)号：US06607504B2
公开(公告)日：2003-08-19
申请号：US09896822
申请日：2001-06-29
申请人： Brett T. Haarala , Brian Bergeron , Paul DiCarlo
发明人： Brett T. Haarala , Brian Bergeron , Paul DiCarlo
IPC分类号： A61M3100
CPC分类号： A61M39/0247 , A61M2039/0261 , A61M2039/0264 , A61M2039/0279 , A61M2039/0282 , A61M2039/0288 , A61M2039/0291
摘要： Medical devices and related methods enable physicians and/or other medical personnel to access percutaneously the interior of a patient. One particular device includes a housing which defines a cavity, a first opening into the cavity, and a second opening into the cavity. The housing is implantable in a patient. The cavity is placed subcutaneously within the patient. The first opening is substantially flush with the surface of the skin of the patient and creates a percutaneous passageway from the exterior of the skin of the patient into the cavity, and the second opening creates a passageway from the cavity into the interior of the patient. A connector is coupled to the second opening and disposed substantially within the cavity to enable a connection between a first device and a second device disposed within the interior of the patient.
摘要翻译：医疗设备和相关方法使得医师和/或其他医务人员能够经皮通过患者的内部。一个特定装置包括限定空腔的壳体，进入空腔的第一开口和进入空腔的第二开口。外壳可植入患者体内。将腔体皮下放置在患者体内。第一开口基本上与患者皮肤表面平齐，并且产生从患者皮肤外部进入空腔的经皮通道，并且第二开口形成从空腔进入患者内部的通道。连接器联接到第二开口并且基本上设置在空腔内，以实现第一装置和设置在患者内部之间的第二装置之间的连接。

40. 发明授权

US06520983B1 Stent delivery system 有权
标题翻译：支架输送系统
公开(公告)号：US06520983B1
公开(公告)日：2003-02-18
申请号：US09270949
申请日：1999-03-17
申请人： Darragh Colgan , Peter A. Hamilton , Paul DiCarlo , Andrew J. Campbell , Sean Gilligan , Albert Chin , Kristian DiMatteo
发明人： Darragh Colgan , Peter A. Hamilton , Paul DiCarlo , Andrew J. Campbell , Sean Gilligan , Albert Chin , Kristian DiMatteo
IPC分类号： A61F206
CPC分类号： A61F2/90 , A61F2/07 , A61F2/95 , A61F2/966 , A61F2002/9517 , A61F2002/9534 , A61F2002/9665 , A61F2210/0076 , A61F2220/0016 , A61F2230/0054 , A61F2250/0098
摘要： The present invention relates to a system for delivering a medical prosthesis into a body lumen. A preferred embodiment of the invention utilizes a catheter having a stent mounted at the distal end that is released into the body lumen by movement of an outer sheath covering the stent in the proximal direction. The stent expands to conform to the inner wall of the lumen and the catheter is withdrawn.
摘要翻译：本发明涉及一种用于将医用假体递送到体腔中的系统。本发明的优选实施例利用具有安装在远端的支架的导管，其通过在近端方向上覆盖支架的外护套的移动而释放到体腔内。支架膨胀以符合内腔的内壁，导管被取出。

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