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    • 33. 发明授权
    • Proteins having effects of controlling cell migration and cell death
    • 蛋白质具有控制细胞迁移和细胞死亡的作用
    • US07829670B2
    • 2010-11-09
    • US12037561
    • 2008-02-26
    • Makoto SatoTakashi Nagano
    • Makoto SatoTakashi Nagano
    • C07K14/00
    • C07K14/4747A61K38/00C07K14/47G01N33/68
    • The present invention relates to proteins which have a role in controlling neuronal cell migration and cell death as well as to the DNA which encode those proteins. It is an object of the present invention to provide control of cell migration and/or cell death by providing a method for screening for promoters or inhibitors of proteins which affect the control of cell migration and/or cell death of neurons by interacting with an actin-binding protein, Filamin 1, through promoting the degradation of Filamin 1 or the DNA encoding Filamin 1. The cDNAs of S-FILIP, L-FILIP and h-FILIP cDNAs, which interact with Filamin 1, thereby negatively affecting cell migration and cell death by promoting the degradation of the Filamin 1, were isolated and the full nucleotide and amino acid sequences thereof were determined.
    • 本发明涉及在控制神经元细胞迁移和细胞死亡以及编码这些蛋白质的DNA中起作用的蛋白质。 本发明的目的是通过提供通过与肌动蛋白相互作用来影响神经元细胞迁移和/或细胞死亡控制的蛋白质启动子或抑制剂的筛选方法来提供对细胞迁移和/或细胞死亡的控制 结合蛋白,Filamin 1,通过促进Filamin 1或编码Filamin 1的DNA的降解。与Filamin 1相互作用的S-FILIP,L-FILIP和h-FILIP cDNA的cDNAs对细胞迁移和细胞有负面影响 分离出促进纤维素1降解的死亡,并确定其全部核苷酸和氨基酸序列。
    • 36. 发明申请
    • SWITCHING POWER SOURCE DEVICE
    • 切换电源设备
    • US20100182808A1
    • 2010-07-22
    • US12664649
    • 2008-03-12
    • Makoto SatoMizuki Utsuno
    • Makoto SatoMizuki Utsuno
    • H02M3/335
    • H02M3/33592Y02B70/1433Y02B70/1475
    • A pseudo-resonant switching power source device is provided which comprises a primary winding 2a of a transformer 2 and a main MOS-FET 3 connected in series to a DC power source 1, a voltage-resonant capacitor 12 connected in parallel to main MOS-FET 3, a rectification smoother 4 connected to a secondary winding 2b of transformer 2 and having a rectification MOS-FET 51 and a smoothing capacitor 6, a synchronized rectification controller 52 for turning rectification MOS-FET 51 on after turning-off of main MOS-FET 3 and turning rectification MOS-FET 51 off before turning-on of main MOS-FET 3, a pulse width elongation circuit 55 for extending on-pulse width of rectification MOS-FET 51, and a main control circuit 8 for producing main drive signals to turn main MOS-FET 3 off and on with operation frequency responsive to on-pulse width of rectification MOS-FET 51 extended by pulse width elongation circuit 55 to vary operation frequency of main MOS-FET 3 so as to restrain noise by high frequency components in main drive signals from main control circuit 8.
    • 提供了一种模拟谐振开关电源装置,其包括变压器2的初级绕组2a和与直流电源1串联连接的主MOS-FET 3,与主MOS-FET并联连接的电压 - 谐振电容器12, FET3,与变压器2的次级绕组2b连接并具有整流MOS-FET51和平滑电容器6的整流平滑器4,用于在主MOS闭合之后使整流MOS-FET51导通的同步整流控制器52 在主MOS-FET 3的导通之前,FETFET3和转向整流MOS-FET51截止,用于延长整流MOS-FET51的脉冲宽度的脉冲宽度延长电路55以及用于产生主MOS-FET3的主控制电路8 驱动信号,使脉冲宽度延长电路55延长的整流MOS-FET51的脉冲宽度响应于操作频率而使主MOS-FET3断开和接通,以改变主MOS-FET 3的工作频率,从而抑制噪声 高频率 来自主控制电路8的主驱动信号中的ncy分量。
    • 37. 发明申请
    • PICKUP DEVICE
    • 扒手装置
    • US20100177619A1
    • 2010-07-15
    • US12376595
    • 2006-10-04
    • Makoto SatoMasakazu OgasawaraTakuma Yanagisawa
    • Makoto SatoMasakazu OgasawaraTakuma Yanagisawa
    • G11B7/00
    • G11B7/0901G11B7/0909G11B7/133G11B7/1353G11B2007/0013
    • A pickup device which, focusing a ray bundle on a track of a recording surface of an optical recording medium to form a light spot, comprises a detection optical system including a photo detector to receive return light reflected from the light spot via an objective lens and perform photoelectric conversion. The photo detector has at least two photoreceptor sections positioned axis-symmetrical with respect to a detection-side division line extending through an optical axis of the return light and parallel to the track. A dividing element placed in an optical path between the photo detector and the objective lens includes at least two inner divided areas positioned axis-symmetrical with respect to a deflection-side division line extending through the optical axis of the return light and parallel to the track, and at least two outer divided areas positioned sandwiching the inner divided areas and axis-symmetrical with respect to the deflection-side division line. The inner divided areas are formed such that parts of a light beam from the other region than overlap regions, divided axis-symmetrically along the deflection-side division line, are exchanged in position across the detection-side division line and directed to the photoreceptor sections of the photo detector so as to be axis-symmetrical with respect to the detection-side division line.
    • 一种拾取装置,其将光束聚焦在光记录介质的记录表面的轨道上以形成光点,包括检测光学系统,其包括光电检测器,以接收经由物镜从光点反射的返回光;以及 执行光电转换。 光检测器具有至少两个相对于延伸通过返回光的光轴并平行于轨道的检测侧分割线轴对称的感光体部分。 放置在光检测器和物镜之间的光路中的分隔元件包括至少两个相对于延伸穿过返回光的光轴并平行于轨道的偏转侧分割线轴对称的内分割区域 以及至少两个外分割区域,其定位为夹着内分割区域并相对于偏转侧分割线轴对称。 内部分割区域被形成为使得来自另一区域的光束的部分比沿着偏转侧分割线轴对称分割的重叠区域的部分在检测侧分割线上交替位置并且被引导到感光体部分 的光检测器相对于检测侧分割线轴对称。
    • 40. 发明申请
    • COMMUNICATIONS APPARATUS AND METHOD, STORAGE MEDIUM, AS WELL AS PROGRAM
    • 通信设备和方法,存储介质,作为程序
    • US20100093286A1
    • 2010-04-15
    • US12640448
    • 2009-12-17
    • Takuro NODAYoriko KomatsuzakiMakoto SatoHiroshi Kakuda
    • Takuro NODAYoriko KomatsuzakiMakoto SatoHiroshi Kakuda
    • H04B17/00G09G5/00G06F3/048
    • H04W48/14H04W84/18
    • The present invention relates to a communications apparatus and method, a storage medium and a program that make it possible for the user to select a device to be made a communications partner more quickly and reliably. The searcher device 21 performs a search so as to detect only one device. If the response message from the searchee device 32 is obtained by the searcher device 21, on the display section of the searcher device 21 is displayed a selection screen for selecting whether or not to make the searchee device 32 a communications partner. If the searchee device 32 is not selected as a communications partner, the searcher device 21 performs another search so as to detect two devices. If the searchee device 31 and the searchee device 32 are detected in the second search, the searcher device 21 excludes the searchee device 32, which was not selected as a communications partner in the previous search, and displays a selection screen for selecting whether or not to perform communications with the searchee device 31. The present invention is applicable to various kinds of communications apparatuses, such as personal computers, PDAs, mobile phones and the like.
    • 本发明涉及通信装置和方法,存储介质和程序,其使得用户可以更快速和可靠地选择要成为通信对象的设备。 搜索器21执行搜索,以仅检测一个设备。 如果搜索设备21获得来自搜索设备32的响应消息,则在搜索器设备21的显示部分上显示用于选择是否使搜索设备32成为通信对方的选择屏幕。 如果搜索设备32未被选择为通信伙伴,则搜索器设备21执行另一搜索,以便检测两个设备。 如果在第二搜索中检测到搜索设备31和搜索设备32,则搜索器设备21排除在先前搜索中未被选择为通信对方的搜索设备32,并且显示用于选择是否选择的选择屏幕 与搜索设备31进行通信。本发明可应用于各种通信设备,例如个人计算机,PDA,移动电话等。