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31. 发明授权

US09554691B2 Endoscopic methods and devices for transnasal procedures 有权
标题翻译：用于经鼻手术的内镜方法和装置
公开(公告)号：US09554691B2
公开(公告)日：2017-01-31
申请号：US11803695
申请日：2007-05-14
申请人： Eric Goldfarb , Thomas R. Jenkins , Isaac J. Kim , Tom T. Vo , Thomas J. Wisted , Daniel T. Harfe
发明人： Eric Goldfarb , Thomas R. Jenkins , Isaac J. Kim , Tom T. Vo , Thomas J. Wisted , Daniel T. Harfe
IPC分类号： A61M25/00 , A61B1/005 , A61B1/00 , A61B1/01 , A61B1/07 , A61B1/233 , A61B17/24 , A61B1/04 , A61B1/06
CPC分类号： A61B1/0051 , A61B1/0014 , A61B1/00154 , A61B1/00165 , A61B1/01 , A61B1/018 , A61B1/04 , A61B1/0607 , A61B1/07 , A61B1/233 , A61B17/24 , A61B2017/246
摘要： Medical devices, systems and methods that are useable to facilitate transnasal insertion and positioning of guidewires and various other devices and instruments at desired locations within the ear, nose, throat, paranasal sinuses or cranium. Direct viewing of such placements via an endoscope.
摘要翻译：医疗装置，系统和方法，其可用于促进导线和各种其他装置和器械在耳，鼻，喉，鼻旁窦或颅骨内的期望位置的鼻鼻插入和定位。通过内窥镜直接观看这种位置。

32. 发明授权

US09089258B2 Endoscopic methods and devices for transnasal procedures 有权
标题翻译：用于经鼻手术的内镜方法和装置
公开(公告)号：US09089258B2
公开(公告)日：2015-07-28
申请号：US11725151
申请日：2007-03-15
申请人： Eric Goldfarb , Thomas R. Jenkins , Isaac J. Kim , Tom T. Vo , Thomas J. Wisted
发明人： Eric Goldfarb , Thomas R. Jenkins , Isaac J. Kim , Tom T. Vo , Thomas J. Wisted
IPC分类号： A61M31/00 , A61B1/005 , A61B1/00 , A61B1/01 , A61B1/233 , A61B17/24 , A61B5/00 , A61B5/06 , A61M25/09
CPC分类号： A61B1/0051 , A61B1/0014 , A61B1/00154 , A61B1/01 , A61B1/233 , A61B5/0084 , A61B5/061 , A61B17/24 , A61B2017/246 , A61M25/09 , A61M2025/09083
摘要： Medical devices, systems and methods that are useable to facilitate transnasal insertion and positioning of guidewires and various other devices and instruments at desired locations within the ear, nose, throat, paranasal sinuses or cranium. Direct viewing of such placements via an endoscope.
摘要翻译：医疗装置，系统和方法，其可用于促进导线和各种其他装置和器械在耳，鼻，喉，鼻旁窦或颅骨内的期望位置的鼻鼻插入和定位。通过内窥镜直接观看这种位置。

33. 发明申请

US20120265094A1 Endoscopic Methods and Devices for Transnasal Procedures 有权
标题翻译：内窥镜检查方法和手术用于经鼻手术
公开(公告)号：US20120265094A1
公开(公告)日：2012-10-18
申请号：US13451453
申请日：2012-04-19
申请人： Eric Goldfarb , Thomas R. Jenkins , Isaac J. Kim , Tom T. Vo , Thomas J. Wisted , Daniel T. Harfe
发明人： Eric Goldfarb , Thomas R. Jenkins , Isaac J. Kim , Tom T. Vo , Thomas J. Wisted , Daniel T. Harfe
IPC分类号： A61B1/018 , A61B10/02 , A61B1/005 , A61B1/06 , A61B1/00 , A61B1/12
CPC分类号： A61B1/0051 , A61B1/0014 , A61B1/00154 , A61B1/00165 , A61B1/01 , A61B1/018 , A61B1/04 , A61B1/0607 , A61B1/07 , A61B1/233 , A61B17/24 , A61B2017/246
摘要： Medical devices, systems and methods that are useable to facilitate transnasal insertion and positioning of guidewires and various other devices and instruments at desired locations within the ear, nose, throat, paranasal sinuses or cranium. Direct viewing of such placements via an endoscope.
摘要翻译：医疗装置，系统和方法，其可用于促进导线和各种其他装置和器械在耳，鼻，喉，鼻旁窦或颅骨内的期望位置的鼻鼻插入和定位。通过内窥镜直接观看这种位置。

34. 发明授权

US06319229B1 Balloon catheter and method of manufacture 失效
标题翻译：球囊导管及制造方法
公开(公告)号：US06319229B1
公开(公告)日：2001-11-20
申请号：US09432990
申请日：1999-11-03
申请人： Isaac J. Kim , Juan T. Domingo , Celso J. Bagaoisan
发明人： Isaac J. Kim , Juan T. Domingo , Celso J. Bagaoisan
IPC分类号： A61M2900
CPC分类号： A61M25/1029 , A61M25/0009 , A61M25/1034 , B29C55/04
摘要： Disclosed herein is a compliant catheter balloon with an improved elastic response and reduced longitudinal expansion, and a method of forming the same. The balloon comprises a SEBS block copolymer, which is longitudinally pre-stretched during the balloon manufacture process. In order to control the working length of a balloon on a catheter, at least one adhesive stop is provided on the catheter which prevents adhesive from wicking into the working length of the balloon. Preferably, a pair of thermoset tubings with an outer diameter size close to the size of the inner diameter of the balloon are inserted on the distal portion of the catheter. After the proper placement of the balloon, the adhesive is applied at the balloon's proximal and distal ends. As the adhesive wicks to the balloon, the thermoset tubings will eventually stop the adhesive to prevent further wicking of adhesive into the balloon's working length. In another aspect of the present invention, there is provided a method of manufacturing a balloon catheter to improve centering of the balloon on the catheter. After a balloon tubing is stretched, the stretched tubing is clamped to a fixture and stabilized at about 100° C. for 15 minutes. This stabilization step ensures that a balloon mounted on a catheter will inflate in a uniform manner.
摘要翻译：本文公开了一种具有改进的弹性响应和减小的纵向膨胀的柔顺导管气囊及其形成方法。气球包含SEBS嵌段共聚物，其在球囊制造过程中被纵向预拉伸。为了控制导管上的气球的工作长度，在导管上提供至少一个粘合阻挡件，其防止粘合剂吸入气球的工作长度。优选地，具有接近球囊内径尺寸的外径尺寸的一对热固管插入导管的远端部分。在适当放置气囊之后，将粘合剂施加在气囊的近端和远端。当粘合剂吸入气球时，热固性管将最终停止粘合剂，以防止粘合剂进一步吸入气囊的工作长度。在本发明的另一方面，提供一种制造球囊导管以改善球囊在导管上的对中的方法。在气囊管被拉伸之后，将拉伸的管道夹紧到夹具上并在约100℃下稳定15分钟。该稳定步骤确保安装在导管上的气囊将以均匀的方式充气。

35. 发明授权

US6050972A Guidewire inflation system 失效
标题翻译：导丝通货膨胀系统
公开(公告)号：US6050972A
公开(公告)日：2000-04-18
申请号：US975723
申请日：1997-11-20
申请人： Gholam-Reza Zadno-Azizi , April A. Marano-Ford , Celso J. Bagaoisan , Jefferey C. Bleam , Isaac J. Kim , Jeffrey F. Field , Roy Leguidleguid , Mukund Patel , George Tsai
发明人： Gholam-Reza Zadno-Azizi , April A. Marano-Ford , Celso J. Bagaoisan , Jefferey C. Bleam , Isaac J. Kim , Jeffrey F. Field , Roy Leguidleguid , Mukund Patel , George Tsai
IPC分类号： A61M25/01 , A61F2/958 , A61M25/00 , A61M25/16 , A61M29/02 , A61M39/00 , A61M29/00
CPC分类号： A61M25/10185 , A61M25/0009 , A61M25/0054 , A61M25/0075 , A61M25/09 , A61M25/09033 , A61M25/1018 , A61M25/104 , A61M2025/0018 , A61M2025/09008 , A61M2025/09175 , A61M2025/1015 , A61M2025/1052 , A61M2025/1079 , A61M2025/1093 , A61M25/0026 , A61M25/10
摘要： Disclosed herein is a low profile catheter valve comprising a movable sealer portion positioned within the inflation lumen of a catheter. The sealer portion forms a fluid tight seal with the inflation lumen by firmly contacting the entire circumference of a section of the inflation lumen. The sealer portion may be positioned proximally of a side-access inflation port on the catheter, to establish an unrestricted fluid pathway between the inflation port and an inflatable balloon on the distal end of the catheter. As desired, the clinician may move the sealer portion to a position distal of the inflation port, thereby preventing any fluid from being introduced into or withdrawn from the balloon via the inflation port. Also disclosed herein is an inflation adaptor for moving the sealer portion within the catheter to establish or close the fluid pathway between the inflation port and the inflatable balloon.
摘要翻译：本文公开了一种低剖面导管阀，其包括位于导管的充气腔内的可移动的密封部分。密封器部分通过牢固地接触充气腔的一部分的整个周边而与充气腔形成流体密封的密封。密封器部分可以位于导管上的侧向通过充气端口的近侧，以在充气端口和导管远端上的可充气气囊之间建立不受限制的流体通路。根据需要，临床医生可以将密封部分移动到充气端口的远侧位置，从而防止任何流体经由充气口引入或从气囊中排出。本文还公开了一种充气适配器，用于移动导管内的密封部分，以建立或关闭充气端口和可膨胀气囊之间的流体通路。

36. 发明授权

US09468362B2 Endoscopic methods and devices for transnasal procedures 有权
公开(公告)号：US09468362B2
公开(公告)日：2016-10-18
申请号：US13451453
申请日：2012-04-19
申请人： Eric Goldfarb , Thomas R. Jenkins , Isaac J. Kim , Tom T. Vo , Thomas J. Wisted , Daniel T. Harfe
发明人： Eric Goldfarb , Thomas R. Jenkins , Isaac J. Kim , Tom T. Vo , Thomas J. Wisted , Daniel T. Harfe
IPC分类号： A61B1/018 , A61B1/233
CPC分类号： A61B1/0051 , A61B1/0014 , A61B1/00154 , A61B1/00165 , A61B1/01 , A61B1/018 , A61B1/04 , A61B1/0607 , A61B1/07 , A61B1/233 , A61B17/24 , A61B2017/246
摘要： Medical devices, systems and methods that are useable to facilitate transnasal insertion and positioning of guidewires and various other devices and instruments at desired locations within the ear, nose, throat, paranasal sinuses or cranium. Direct viewing of such placements via an endoscope.

37. 发明申请

US20090030274A1 ENDOSCOPIC METHODS AND DEVICES FOR TRANSNASAL PROCEDURES 审中-公开
标题翻译：内镜方法和手术方法
公开(公告)号：US20090030274A1
公开(公告)日：2009-01-29
申请号：US12184166
申请日：2008-07-31
申请人： Eric Goldfarb , Thomas R. Jenkins , Isaac J. Kim , Tom T. Vo , Thomas J. Wisted
发明人： Eric Goldfarb , Thomas R. Jenkins , Isaac J. Kim , Tom T. Vo , Thomas J. Wisted
IPC分类号： A61B1/01 , A61B1/018
CPC分类号： A61B1/0051 , A61B1/0014 , A61B1/00154 , A61B1/01 , A61B1/233 , A61B5/0084 , A61B5/061 , A61B17/24 , A61B2017/246 , A61M2025/09083
摘要： Medical devices, systems and methods that are useable to facilitate transnasal insertion and positioning of guidewires and various other devices and instruments at desired locations within the ear, nose, throat, paranasal sinuses or cranium. Direct viewing of such placements via an endoscope.
摘要翻译：医疗装置，系统和方法，其可用于促进导线和各种其他装置和器械在耳，鼻，喉，鼻旁窦或颅骨内的期望位置的鼻鼻插入和定位。通过内窥镜直接观看这种位置。

38. 发明授权

US06355014B1 Low profile catheter valve 失效
标题翻译：薄型导管阀
公开(公告)号：US06355014B1
公开(公告)日：2002-03-12
申请号：US09039110
申请日：1998-03-13
申请人： Gholam-Reza Zadno-Azizi , April A. Marano-Ford , Celso J. Bagaoisan , Jeffrey C. Bleam , Isaac J. Kim , Jeffrey F. Field
发明人： Gholam-Reza Zadno-Azizi , April A. Marano-Ford , Celso J. Bagaoisan , Jeffrey C. Bleam , Isaac J. Kim , Jeffrey F. Field
IPC分类号： A61M2900
CPC分类号： A61M25/10185 , A61M25/0009 , A61M25/0026 , A61M25/0054 , A61M25/0075 , A61M25/09 , A61M25/09033 , A61M25/10 , A61M25/104 , A61M2025/0018 , A61M2025/09008 , A61M2025/09175 , A61M2025/1015 , A61M2025/1052 , A61M2025/1079 , A61M2025/1093
摘要： Disclosed herein is a low profile catheter valve comprising a movable sealer portion positioned within the inflation lumen of a catheter. The sealer portion forms a fluid tight seal with the inflation lumen by firmly contacting the entire circumference of a section of the inflation lumen. The sealer portion may be positioned proximally of a side-access inflation port on the catheter, to establish an unrestricted fluid pathway between the inflation port and an inflatable balloon on the distal end of the catheter. As desired, the clinician may move the sealer portion to a position distal of the inflation port, thereby preventing any fluid from being introduced into or withdrawn from the balloon via the inflation port.
摘要翻译：本文公开了一种低剖面导管阀，其包括位于导管的充气腔内的可移动的密封部分。密封器部分通过牢固地接触充气腔的一部分的整个周边而与充气腔形成流体密封的密封。密封器部分可以位于导管上的侧向通过充气端口的近侧，以在充气端口和导管远端上的可充气气囊之间建立不受限制的流体通路。根据需要，临床医生可以将密封部分移动到充气端口的远侧位置，从而防止任何流体经由充气口引入或从气囊中排出。

39. 发明授权

US06325777B1 Low profile catheter valve and inflation adaptor 有权
标题翻译：薄型导管阀和充气适配器
公开(公告)号：US06325777B1
公开(公告)日：2001-12-04
申请号：US09410456
申请日：1999-10-01
申请人： Gholam-Reza Zadno-Azizi , April A. Marano-Ford , Celso J. Bagaoisan , Jefferey C. Bleam , Isaac J. Kim , Jeffrey F. Field , Roy Leguidleguid , Mukund Patel , George Tsai
发明人： Gholam-Reza Zadno-Azizi , April A. Marano-Ford , Celso J. Bagaoisan , Jefferey C. Bleam , Isaac J. Kim , Jeffrey F. Field , Roy Leguidleguid , Mukund Patel , George Tsai
IPC分类号： A61M2900
CPC分类号： A61M25/10185 , A61M25/0009 , A61M25/0026 , A61M25/0054 , A61M25/0075 , A61M25/09 , A61M25/09033 , A61M25/10 , A61M25/104 , A61M2025/0018 , A61M2025/09008 , A61M2025/09175 , A61M2025/1015 , A61M2025/1052 , A61M2025/1079 , A61M2025/1093
摘要： Disclosed herein is a low profile catheter valve comprising a movable sealer portion positioned within the inflation lumen of a catheter. The sealer portion forms a fluid tight seal with the inflation lumen by firmly contacting the entire circumference of a section of the inflation lumen. The sealer portion may be positioned proximally of a side-access inflation port on the catheter, to establish an unrestricted fluid pathway between the inflation port and an inflatable balloon on the distal end of the catheter. As desired, the clinician may move the sealer portion to a position distal of the inflation port, thereby preventing any fluid from being introduced into or withdrawn from the balloon via the inflation port. Also disclosed herein is an inflation adaptor for moving the sealer portion within the catheter to establish or close the fluid pathway between the inflation port and the inflatable balloon.
摘要翻译：本文公开了一种低剖面导管阀，其包括位于导管的充气腔内的可移动的密封部分。密封器部分通过牢固地接触充气腔的一部分的整个周边而与充气腔形成流体密封的密封。密封器部分可以位于导管上的侧向通过充气端口的近侧，以在充气端口和导管远端上的可充气气囊之间建立不受限制的流体通路。根据需要，临床医生可以将密封部分移动到充气端口的远侧位置，从而防止任何流体经由充气口引入或从气囊中排出。本文还公开了一种充气适配器，用于移动导管内的密封部分，以建立或关闭充气端口和可膨胀气囊之间的流体通路。

40. 发明授权

US06500147B2 Flexible catheter 有权
标题翻译：柔性导管
公开(公告)号：US06500147B2
公开(公告)日：2002-12-31
申请号：US09253591
申请日：1999-02-22
申请人： Samuel L. Omaleki , Isaac J. Kim , Jefferey C. Bleam , Juan T. Domingo , Andres D. Tomas , Celso J. Bagaoisan
发明人： Samuel L. Omaleki , Isaac J. Kim , Jefferey C. Bleam , Juan T. Domingo , Andres D. Tomas , Celso J. Bagaoisan
IPC分类号： A61M2900
CPC分类号： A61M25/104 , A61M25/0054 , A61M25/09 , A61M25/09033 , A61M2025/0098 , A61M2025/09008 , A61M2025/09183 , A61M2025/1079 , A61M2025/1093
摘要： A balloon catheter having improved flexibility in and about its distal end is provided. The flexibility of the catheter is determined in part by improving the properties of a wire or catheter located within the area where the balloon is mounted. In one aspect of the present invention, connecting wires extend through the balloon from the distal end of a catheter body to the proximal end of a core wire. The core wire extends distally away from the connecting wires and the catheter body. In another aspect of the present invention, a core wire is provided having a proximal end extending within the balloon into the catheter tubular body but is not mounted therein. This allows the proximal end of the core wire to “float” within the tubular body, such that when the catheter is advanced through the vasculature of a patient, the core wire may move longitudinally within the tubular body. In another aspect of the present invention, the balloon is mounted over a tubular body which is configured to give the catheter longitudinal flexibility.
摘要翻译：提供了具有在其远端中及其远端具有改进的柔性的球囊导管。导管的灵活性部分地通过改进位于安装气球的区域内的线或导管的性质来确定。在本发明的一个方面，连接线从导管主体的远端延伸穿过球囊到芯线的近端。芯线远离连接线和导管主体延伸。在本发明的另一方面，提供了一种芯线，其具有在气囊内延伸到导管管状体中但未安装在其中的近端。这允许芯线的近端在管状体内“漂浮”，使得当导管前进通过患者的脉管系统时，芯线可以在管状体内纵向移动。在本发明的另一方面，气囊被安装在管状体上，该管状体被配置成给予导管的纵向柔性。

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