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31. 发明申请

US20060068928A1 Golf club with customizable alignment sighting & weighting device 失效
标题翻译：高尔夫俱乐部，可定制瞄准和加重装置
公开(公告)号：US20060068928A1
公开(公告)日：2006-03-30
申请号：US10949076
申请日：2004-09-24
申请人： Lajos Nagy
发明人： Lajos Nagy
IPC分类号： A63B69/36 , A63B53/06
CPC分类号： A63B53/04 , A63B53/0466 , A63B53/047 , A63B53/0487 , A63B60/00 , A63B69/3632 , A63B69/3685 , A63B2053/0437 , A63B2053/0441 , A63B2053/0491
摘要： A customizable alignment sighting device for a golf club is mounted to an upper surface of the head of the golf club with a sighting element providing the user a visual target indicator for desired alignment of the club head with the user's line of sight. The sighting element can be readily adjusted for the user's preferences. When not aligned, the sighting element provides an indication of the magnitude and direction of misalignment. In one embodiment, the device is shaped as a planar disc mounted on the upper surface of the club head by leveling posts spaced around its periphery. The sighting element is a concave lens or lenticulated grid or grill superimposed on a target image. In another embodiment, the device has a 3D device body mounted in a mounting cup or socket fastened to or formed in the head of the golf club. The device body has a larger-diameter circle marked around an annular opening, and a smaller-diameter circle marked depthwise inside the opening in the device body to provide a target of concentric circles by parallax effect. The device body can be formed as a sphere with axially split sides that are expanded outward when an expansion plug is threaded in the bottom, providing an interference fit holding it in position in the mounting cup. The spherical body can be formed with 4 alignment sighting holes at 90° intervals around a vertical plane and provided with a weighting element fixed at an offset position, such that it can be rotated to use any of the different alignment holes for adjusting the weight distribution in the club head.
摘要翻译：用于高尔夫球杆的可定制的对准瞄准装置安装在高尔夫球杆的头部的上表面，其具有瞄准元件，为瞄准器提供用于使球杆头与用户视线的期望对准的视觉目标指示器。可以根据用户的喜好容易地调整瞄准元件。当不对准时，瞄准元件提供未对准的大小和方向的指示。在一个实施例中，该装置被成形为平面盘，其通过围绕其周边间隔的平台安装在球杆头的上表面上。瞄准元件是叠加在目标图像上的凹透镜或微透镜格栅或格栅。在另一个实施例中，该装置具有安装在固定于高尔夫球杆头部或形成于高尔夫球杆头部的安装杯或插座中的3D装置主体。装置主体具有围绕环形开口标记的较大直径的圆圈，以及在装置主体的开口内部深度方向标记的较小直径的圆，以通过视差效应提供同心圆的目标。装置主体可以形成为具有轴向分开的侧面的球体，当膨胀塞螺纹穿过底部时向外扩张，从而提供了将其保持在安装杯中的位置的过盈配合。球形体可以围绕垂直平面以90°的间隔形成有4个定位瞄准孔，并且设置有固定在偏移位置的加权元件，使得其可以旋转以使用任何不同的对准孔来调节重量分布在球杆头。

32. 发明申请

US20050153973A1 Compounds 失效
标题翻译：化合物
公开(公告)号：US20050153973A1
公开(公告)日：2005-07-14
申请号：US10518114
申请日：2003-06-11
申请人： Peter Aranyl , Laszlo Balazs , Imre Bata , Sandor Batori , Eva Boronkay , Zoltan Kapui , Edit Susan , Tibor Szabo , Lajos Nagy , Katalin Urban-Szabo , Marton Varga
发明人： Peter Aranyl , Laszlo Balazs , Imre Bata , Sandor Batori , Eva Boronkay , Zoltan Kapui , Edit Susan , Tibor Szabo , Lajos Nagy , Katalin Urban-Szabo , Marton Varga
IPC分类号： A61K31/439 , A61K31/444 , A61K31/496 , A61K31/506 , A61P3/00 , A61P3/10 , A61P13/12 , A61P17/00 , A61P25/18 , A61P25/22 , A61P29/00 , A61P31/18 , A61P35/00 , A61P37/06 , A61P37/08 , A61P43/00 , C07D207/06 , C07D207/16 , C07D263/06 , C07D277/06 , C07D451/04 , C07D451/14 , C07D417/14 , A61K31/4439 , A61K31/497 , A61K31/501
CPC分类号： C07D451/04 , C07D207/06 , C07D207/16 , C07D263/06 , C07D277/06 , C07D451/14
摘要： Heterocyclic amides useful as inhibitors of dipeptylpeptidase-IV (DPP-IV) enzyme, process for the preparation thereof and intermediates therefore.
摘要翻译：可用作二肽肽酶-IV（DPP-IV）酶抑制剂的杂环酰胺，因此其制备方法和中间体。

33. 发明授权

US06600039B1 PROCESS FOR THE PREPARATION OF N-(1,1-DIMETHYLETHYL)-4-[[5′-ETHOXY-4-CIS[2-(4-MORPHOLINO)ETHOXY]-2′-OXOSPIRO[CYCLOHEXAN-1,3′[H]INDOL]1′(2′-H)-YL]-SULFONYL]-3-METHOXYBENZAMIDE AND ITS SALTS 失效
标题翻译：制备N-（1,1-二甲基乙基）-4 - [[5'-乙氧基-4- CIS [2-（4-吗啉基）乙氧基] -2'-氧代吡咯并[环己基] -1,3- H]吲哚] 1'（2'-H）-YL] - 磺基] -3-甲氧基苯甲酸及其盐
公开(公告)号：US06600039B1
公开(公告)日：2003-07-29
申请号：US10030647
申请日：2002-04-17
申请人： Gergely Héja , Éva Csikós , Tünde Erösné Takácsy , Csaba Gönczi , Judit Halász , István Hermecz , Csilla Majláth , Lajos Nagy , Andrea Sántáné Csutor , Péter Sárosi , Kálmán Simon , Tiborné Szomor , Györgyné Szvoboda
发明人： Gergely Héja , Éva Csikós , Tünde Erösné Takácsy , Csaba Gönczi , Judit Halász , István Hermecz , Csilla Majláth , Lajos Nagy , Andrea Sántáné Csutor , Péter Sárosi , Kálmán Simon , Tiborné Szomor , Györgyné Szvoboda
IPC分类号： C07D27300
CPC分类号： C07D209/96
摘要： The invention relates to a process for the preparation of a compound of formula (I) and the salts thereof by reacting the compound of formula (II) with the compound of formula (III), which comprises carrying out the reaction in dimethyl sulfoxide, at a temperature between 10° C. and 40° C., preferably at room temperature and transforming the resulting base of formula (I), if desired, into its salt by a method known per se.
摘要翻译：本发明涉及制备式（I）化合物及其盐的方法，其通过使式（II）化合物与式（III）化合物反应，其包括在二甲基亚砜中进行反应，温度在10℃至40℃之间，优选在室温下，如果需要，通过本身已知的方法将得到的式（I）碱转化成其盐。

34. 发明授权

US06573386B1 Process for the preparation of spiro[(4-cyclohexanone)-[3H]indol]-2′[1′H]-one derivatives 失效
标题翻译：制备螺[（4-环己酮） - [3H]吲哚] -2'[1'H] - 酮衍生物的方法
公开(公告)号：US06573386B1
公开(公告)日：2003-06-03
申请号：US10030648
申请日：2002-04-17
申请人： Csaba Gönczi , Éva Csikós , István Hermecz , Gergely Héja , Árpád Illár , Lajos Nagy , Andrea Sántáné Csutor , Attila Simon , Kálmán Simon , Ágota Smelkóné Esek , Tiborné Szomor , Györgyné Szvoboda
发明人： Csaba Gönczi , Éva Csikós , István Hermecz , Gergely Héja , Árpád Illár , Lajos Nagy , Andrea Sántáné Csutor , Attila Simon , Kálmán Simon , Ágota Smelkóné Esek , Tiborné Szomor , Györgyné Szvoboda
IPC分类号： C07D20954
CPC分类号： C07D405/04 , C07D209/34 , C07D209/96 , Y02P20/55
摘要： The invention relates to a process for the preparation of spiro [(4-cyclohexanone)-[3H]indol]-2′[1′H]-one derivatives of general formula I—wherein R1 and R2 independently stand for hydrogen, C1-4alkyl, C1-4alkoxy, C1-4alkylthio, C1-4polyfluoroalkyl, C1-4polyfluoroalkoxy, C3-7cycloalkyloxy, C3-7cycloalkylthio, phenoxy, benzyloxy or nitro group—, characterized by reacting an indolin-2-one derivative of general formula II—wherein R1 and R2 are as defined above—with a compound capable for introducing a protective group, coupling the compound of general formula III, thus obtained—wherein R1 and R2 are as defined above and A stands for a protective group—with acrylic acid C1-4ester; cyclizing the resulting compound of general formula IV—wherein R1 and R2 are as defined above—with a compound capable for introducing a protective group, coupling the compound of formula III thus obtained,—wherein R1 and R2 are as defined above and A stands for a protective group—with an acrylic acid C1-4ester, cyclizing the resulting compound of formula IV—wherein R1 and R2 are as defined above R3 stands for C1-4alkyl and A stands for a protective group—, eliminating the—COOR3 group and the A protective group of the keto-ester of general formula V—wherein R1 and R2 are as defined above, R3 stands for C1-4alkyl and A stands for a protective group—, optionally without isolation of the compounds of general formulae IV and/or V and/or VI.
摘要翻译：本发明涉及制备通式I的螺[（4-环己酮） - [3 H]吲哚] -2'[1'H] - 酮衍生物的方法，其中R 1和R 2独立代表氢，C1- 4-烷基，C 1-4烷氧基，C 1-4烷硫基，C 1-4多氟烷基，C 1-4多氟烷氧基，C 3-7环烷氧基，C 3-7环烷硫基，苯氧基，苄氧基或硝基，其特征在于使通式II的二氢吲哚-2-酮衍生物 - R1和R2如上定义 - 与能够引入保护基团的化合物偶合，由此得到的通式III化合物 - 其中R 1和R 2如上所定义，A代表保护基 - 与丙烯酸C1- 4ester; 使所得到的通式IV化合物（其中R 1和R 2如上定义）与可引入保护基的化合物环化，将所得式III化合物偶联，其中R 1和R 2如上所定义，A代表保护基 - 与丙烯酸C1-4酯，使所得到的式IV化合物环化，其中R 1和R 2如上所定义。R3代表C 1-4烷基，A代表保护基，除去-COOR 3基团和通式V的酮酯的保护基 - 其中R 1和R 2如上所定义，R 3表示C 1-4烷基，A代表保护基 - 任选地不分离通式IV和/或 V和/或VI。

35. 发明授权

US5639905A Process for preparing N-phenyl-N-methoxyacetyl-DL-alanine methyl ester derivatives 失效
标题翻译：制备N-苯基-N-甲氧基乙酰基-DL-丙氨酸甲酯衍生物的方法
公开(公告)号：US5639905A
公开(公告)日：1997-06-17
申请号：US368271
申请日：1994-09-13
申请人： Lajos Nagy , Jeno Pelyva , Pal Agocs , Csaba Soptei , Judit Benczik nee Pasztor , Zoltan Kolonics , Sandor Balint , Dezso Sebok , Jolan Cseke , Tibor Kranitz , Laszlo Legradi
发明人： Lajos Nagy , Jeno Pelyva , Pal Agocs , Csaba Soptei , Judit Benczik nee Pasztor , Zoltan Kolonics , Sandor Balint , Dezso Sebok , Jolan Cseke , Tibor Kranitz , Laszlo Legradi
IPC分类号： C07C1/12 , C07C231/08 , C07C235/16 , C07C235/68 , C07C269/04
CPC分类号： C07C235/16 , C07C231/08 , C07C235/68
摘要： Process for the preparation of N-phenyl-N-methoxyacetyl-DL-alanine methyl ester derivatives of the formula (I). ##STR1## wherein R is a C.sub.1-4 alkyl residue; and n is a cardinal number between from 1 to 3,which comprises reacting an N-methoxyacetyl derivative of the formula (II). ##STR2## wherein R and n are as defined above, with a stoichiometric amount of an alkaline metal alkoxide, at a temperature between 80.degree. C. and 150.degree. C., until completion of the removal of the alkanol present in the system, then reacting the thus obtained alkaline metal salt of the compound of formula (II) directly or after isolation with a methyl DL-x-halopropionate.
摘要翻译：制备式（I）的N-苯基-N-甲氧基乙酰基-DL-丙氨酸甲基酯衍生物的方法。（I）其中R是C 1-4烷基残基; n为1〜3的基数，包括使式（II）的N-甲氧基乙酰基衍生物反应。其中R和n如上所定义，化学计量的碱金属醇盐在80℃至150℃之间，直至完全除去存在于然后将由此得到的式（II）化合物的碱金属盐直接或分离后与DL-x-卤代丙酸甲酯反应。

36. 发明授权

US4859772A Process for the preparation of 3-isopropyl-benzo-2-thia-1,3-diazinone-(4)-2,2-dioxide 失效
标题翻译：制备3-异丙基 - 苯并-2-硫杂-1,3-二嗪酮 - （4）-2,2-二氧化物的方法
公开(公告)号：US4859772A
公开(公告)日：1989-08-22
申请号：US105230
申请日：1987-07-15
申请人： Jeno Pelyva , K. Istvan Vecsey , Zoltan Kolonics , Laszlo Legradi , Lajos Nagy , Andras Horvath , Ferenc Fodor, deceased , Csaba Soptei , Dezso Sebok , Elemer Tomordi , Laszlo Lendvai , Bela Karacsonyi , Erzsebet Dioszegi
发明人： Jeno Pelyva , K. Istvan Vecsey , Zoltan Kolonics , Laszlo Legradi , Lajos Nagy , Andras Horvath , Ferenc Fodor, deceased , Csaba Soptei , Dezso Sebok , Elemer Tomordi , Laszlo Lendvai , Bela Karacsonyi , Erzsebet Dioszegi
IPC分类号： C07D285/16
CPC分类号： C07D285/16
摘要： The present invention relates to a process for the preparation of 3-isopropyl-benzo-2-thia-1,3-diazinone-(4)-2,2-dioxide which comprises preparing isopropyl sulfamoyl chloride in one step by reacting N,N'-diisopropyl-urea with phosphorus trichloride and chlorine in the presence of oleum and sulfuric acid and condensing the so obtained isopropyl sulfamoyl chloride at room temperature without any solvent in the presence of an excess of N,N-diethyl aniline with anthranylic acid methyl ester and subjecting the thus obtained N-isopropyl-N'-o-carbomethoxy-phenyl-sulfamide to cyclization in the presence of sodium methylate, extracting the obtained crude 3-isopropyl-benzo-2-thia-1,3-diazinone-(4)-2,2-dioxide with a mixture of methanol and water and after adding water to the aqueous-methanolic mixture and sedimenting the contaminations isolating a product of high purity.
摘要翻译： PCT No.PCT / HU86 / 00065 Sec。 371日期1987年7月15日 102（e）日期1987年7月15日PCT提交1986年12月3日PCT公布。第WO87 / 03588号公报日本6月18日，1987。本发明涉及3-异丙基 - 苯并-2-硫杂-1,3-二嗪酮 - （4）-2,2-二氧化物的制备方法，其包括制备异丙基氨磺酰氯在发烟硫酸和硫酸的存在下，使N，N'-二异丙基脲与三氯化磷和氯反应一步，在室温下将所得异丙基氨磺酰氯在没有任何溶剂的条件下，在过量的N，二乙基苯胺与苯甲酸甲酯反应，并将得到的N-异丙基-N'-邻甲氧基苯基磺酰胺在甲醇钠存在下环化，得到粗产物3-异丙基 - 苯并-2-硫杂-1- （4）-2,2-二氧化物与甲醇和水的混合物，并在向含水甲醇混合物中加入水并沉淀分离高纯度产物的污染物。

37. 发明授权

US4788217A Pesticidal carbamates 失效
标题翻译：杀虫氨基甲酸酯
公开(公告)号：US4788217A
公开(公告)日：1988-11-29
申请号：US901448
申请日：1986-07-21
申请人： Grorgy Lanyi , Lajos Nagy , Eva Somfai , Valeria Denes nee Lustig , Erzsebet Radvany nee Hegedos , Leszloo Pap , Tamas Detre , Andras Szego , Maria Visnyovszky neee Bvez
发明人： Grorgy Lanyi , Lajos Nagy , Eva Somfai , Valeria Denes nee Lustig , Erzsebet Radvany nee Hegedos , Leszloo Pap , Tamas Detre , Andras Szego , Maria Visnyovszky neee Bvez
IPC分类号： A01N47/18 , A01N47/22 , A01P5/00 , A01P7/02 , A01P7/04 , C07D307/86 , A01N47/10
CPC分类号： A01N47/22 , C07D307/86
摘要： The invention relates to new compounds of the Formula I ##STR1## wherein R.sup.2 stands for hydrogen or C.sub.1-4 alkyl; andR.sup.3 represents C.sub.1-4 alkyl or a group of the Formula R.sup.4 --(CH.sub.2).sub.n -- wherein n is 1 or 2;R.sup.4 represents C.sub.1 to C.sub.4 alkoxy-carbonylor a group of the Formula II ##STR2## and R.sup.6 and R.sup.7 stand for hydrogen or C.sub.1-4 alkoxy; orR.sup.2 and R.sup.3 together may form a group of the Formula --(CH.sub.2).sub.2 --O--CH.sub.2).sub.2 -- with the proviso that R.sup.2 and R.sup.3 do not both stand for methyl, and salts thereof and a process for the preparation of the same.
摘要翻译： PCT No.PCT / HU85 / 00068 Sec。一九八六年七月二十一日 102（e）日期1986年7月21日PCT提交1985年11月15日PCT公布。出版物WO86 / 03202 日期：1986年6月5日。本发明涉及式I的新化合物（Ⅰ），其中R2代表氢或C1-4烷基; 并且R 3表示C 1-4烷基或式R4-（CH 2）n - 的基团，其中n为1或2; R 4表示C 1至C 4烷氧基 - 羰基或式II的基团（II），R 6和R 7表示氢或C 1-4烷氧基; 或者R 2和R 3一起可以形成式 - （CH 2）2 -O-CH 2）2 - ，条件是R 2和R 3不同时代表甲基，及其盐及其制备方法。

38. 发明授权

US4564706A Process for the preparation of propargyl amines 失效
标题翻译：炔丙胺的制备方法
公开(公告)号：US4564706A
公开(公告)日：1986-01-14
申请号：US514149
申请日：1983-07-14
申请人： Zoltan Ecsery , Eva Somfai , Judit Hermann nee Voros , Lajos Nagy , Gabor Szabo , Otto Orban , Laslzo Arvai
发明人： Zoltan Ecsery , Eva Somfai , Judit Hermann nee Voros , Lajos Nagy , Gabor Szabo , Otto Orban , Laslzo Arvai
IPC分类号： C07C67/00 , C07C209/00 , C07C209/08 , C07C211/63 , C07C87/28 , C07C85/04
CPC分类号： C07C209/08
摘要： The invention relates to a new process for the preparation of propargyl ammonium chlorides of the Formula I ##STR1## by alkaline decomposition of the d-tartarate of the 1-isomer of an amine of the Formula II ##STR2## and subsequent reaction of the amine of the Formula II with a halide of the Formula IIIX--CH.sub.2 --C.tbd.CH (III)in the presence of an organic solvent, alkali and waterin which in Formulae II and III respectively,n is 1 or 0 andX stands for halogenwhich comprises reacting the d-tartarate of the 1-isomer of an amine of the Formula II in aqueous suspension with an alkali, dissolving the base of the Formula II, thus set free without isolation in a water non-miscible organic solvent and reacting the same in the said phase with a halide of the Formula III, and thereafter--preferably after separating the aqueous layer--reacting the mixture which contains the amines of the Formulae II and IV ##STR3## in the organic phase in the presence of water with an organic acid or a solution which has a pH value of 1.5-6 and consists of an inorganic acid and water, thus dissolving in the two-phase mixture formed the salt of the amine of the Formula II in the aqueous layer and selectively separating the amine of the Formula II from the amine of the Formula IV, and thereafter adding after the separation of the phases hydrogen chloride to the amine of the Formula IV being in the organic phase and thus precipitating the salt of the Formula I.The compounds of Formula I are known pharmaceutical active ingredients. The advantage of the process of the present invention that it is highly economical and enables the recovery of the starting materials on large scale production too.
摘要翻译：本发明涉及通过碱式分解通式II（XIIX）的胺的1-异构体的d-酒石酸来制备式I的炔丙基氯化铵的新方法（I）和随后的式II的胺与式III的X-CH 2 -C 3 CH 3（III）的卤化物在有机溶剂，碱和水的存在下分别反应，其中式II和III分别为n为1 或0和X表示卤素，其包括使式II的胺的1-异构体在水悬浮液中与碱反应，溶解式II的碱，因此在不分离的情况下在水中非游离在所述相中与其反应，与式III的卤化物反应，然后优选在将含有式II和IV的胺的混合物（IV）的水层分离成在有机酸存在下的有机相或pH值为1.5-6且由无机酸和水组成的溶液，因此溶解在两相混合物中形成水性层中式II的胺的盐，并选择性地分离式II的式II化合物，然后在将相氯化氢分离为式IV的胺之后加入有机相，由此沉淀式I的盐。式I的化合物是已知的药用活性成分。本发明方法的优点是高度经济且能够在大规模生产中回收原料。

39. 发明授权

US4403776A Logic toy 失效
标题翻译：逻辑玩具
公开(公告)号：US4403776A
公开(公告)日：1983-09-13
申请号：US257920
申请日：1981-04-27
申请人： Gyula Subotics , Gyulane Subotics , Lajos Nagy
发明人： Gyula Subotics , Gyulane Subotics , Lajos Nagy
IPC分类号： G09B29/00 , A63F3/04 , A63F9/00 , A63F9/06 , A63F9/08
CPC分类号： A63F9/24 , A63F9/0873 , A63F2003/00649 , A63F2003/0439 , A63F2003/0444 , A63F2009/2451 , A63F9/0604 , A63F9/0612
摘要： A logic toy for distinctive indication of bordering zones on a surface, especially existing administrative districts, such as countries, facilitating herewith the development of logic way of thinking and depth perception together with the memorization of colored vision or other kind of signalling. The body of the logic toy is for example a parallelepiped, a sphere or globe or the like, the surface thereof is divided into separated zones, whereby the body is provided with built-in signalling means for displaying a signal simultaneously for each separated zone. Comparing the logic toy according to the invention to the known logic toys, such as the magic cube or the like, it means in each occasion a new logic task to be solved, therefore the playing can not become a routine work. Furthermore, a given task can be solved in different ways, and the tasks can be made gradually more and more complicated.
摘要翻译：一个逻辑玩具，用于特别指示表面上的边界区域，特别是现有的行政区域，如国家，随着逻辑思维方式和深度感知的发展，以及彩色视觉或其他类型信号的记忆的发展。逻辑玩具的主体例如是平行六面体，球体或球体等，其表面被分成分离的区域，由此身体设置有内置的信号装置，用于同时为每个分离的区域显示信号。将根据本发明的逻辑玩具与诸如魔法等的已知逻辑玩具进行比较，这意味着在每种场合都需要解决新的逻辑任务，因此玩法不能成为日常工作。此外，可以以不同的方式解决给定的任务，任务逐渐变得越来越复杂。

40. 发明授权

US4369252A Fermentation process for the preparation of ergot alkaloids, primarily ergocornine and .beta.-ergocryptine 失效
标题翻译：用于制备麦角生物碱的发酵方法，主要是麦角糖和β-麦角蛋白
公开(公告)号：US4369252A
公开(公告)日：1983-01-18
申请号：US232172
申请日：1981-02-06
申请人： Geza Wack , Janos Kiss , Zsuzsa Lengyel nee Szemenyei , Lajos Nagy , Eva Udvardy Nagy nee Cserey Pechany , Karoly Zalai , Erzsebet Zsoka nee Somkuti
发明人： Geza Wack , Janos Kiss , Zsuzsa Lengyel nee Szemenyei , Lajos Nagy , Eva Udvardy Nagy nee Cserey Pechany , Karoly Zalai , Erzsebet Zsoka nee Somkuti
IPC分类号： C12P21/00 , A61K35/66 , C07D519/02 , C12P1/06 , C12P17/18 , C12R1/645 , C12N1/14
CPC分类号： C12P17/183 , C07D519/02 , Y10S435/911
摘要： The invention relates to a new process for the preparation of ergot alkaloids, primarily ergocornine and .beta.-ergocryptine, by subjecting a Claviceps purpurea strain to fermentation under aerobic conditions in a culture medium which contains carbon and nitrogen sources, mineral salts and optionally other additives, too. According to the invention a Claviceps purpurea variant strain deposited under No. MNG 00186 is applied as alkaloid-producing strain.
摘要翻译：本发明涉及通过使Claviceps紫草菌株在需氧条件下在含有碳源和氮源的培养基，矿物盐和任选的其它添加剂中发酵来制备麦角生物碱，主要是麦角糖和β-麦角灵素的新方法，太。根据本发明，以生物碱生产菌株的形式施用在MNG 00186号下保藏的克拉维酵母紫薇变体菌株。

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