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31. 发明申请

US20070153044A1 Methods and apparatuses for sensing temperature of multi-via heater chips 有权
标题翻译：用于感测多通道加热器芯片温度的方法和装置
公开(公告)号：US20070153044A1
公开(公告)日：2007-07-05
申请号：US11323809
申请日：2005-12-30
申请人： Lucas Barkley , Bruce Gibson , Eric Hall , David King , George Parish
发明人： Lucas Barkley , Bruce Gibson , Eric Hall , David King , George Parish
IPC分类号： B41J29/38
CPC分类号： B41J2/195 , B41J2/04563 , B41J2/0458
摘要： Heater chips for use with a printing device, such as heater chips that include a first heater array, positioned substantially adjacent a first via, and a second heater array, positioned substantially adjacent a second via. The heater chip can also include a region, positioned between the first heater array and the second heater array, and a temperature sensing element operable to sense the temperature of the region, where the temperature sensing element is substantially centrally disposed with respect to the region. According to one embodiment of the invention, the temperature sensing element comprises a temperature sensing resistor.
摘要翻译：用于与打印装置一起使用的加热器芯片，例如包括基本上邻近第一通孔定位的第一加热器阵列的加热器芯片和基本上邻近第二通孔定位的第二加热器阵列。加热器芯片还可以包括位于第一加热器阵列和第二加热器阵列之间的区域，以及温度感测元件，其可操作以感测区域的温度，其中温度感测元件相对于该区域基本上居中设置。根据本发明的一个实施例，温度感测元件包括温度感测电阻器。

32. 发明申请

US20070031423A1 Antibodies to treat cancer 有权
标题翻译：治疗癌症的抗体
公开(公告)号：US20070031423A1
公开(公告)日：2007-02-08
申请号：US11414532
申请日：2006-04-28
申请人： Gary Fanger , Neil Fanger , David King , Marc Retter , Kenneth Rock
发明人： Gary Fanger , Neil Fanger , David King , Marc Retter , Kenneth Rock
IPC分类号： A61K39/395 , C08B37/00 , C07K16/30
CPC分类号： C07K16/30 , A61K2039/505 , C07K2317/73 , C07K2317/732
摘要： Compositions and methods for the treatment of cancer, particularly melanoma, myeloma, small cell lung cancer, thymic lymphoma, T-cell lymphoma, B-cell lymphoma, osteosarcoma, and acute T-cell leukemia, are disclosed. Illustrative compositions include one or more anti-ganglioside antibodies and polynucleotides that encode such anti-ganglioside antibodies. These antibodies may be for example, hamster antibodies, chimeric human/hamster antibodies, or humanized antibodies. The disclosed compositions are useful, for example, in the treatment of cancer and can be used to induce apoptosis in a cancer cell.
摘要翻译：公开了用于治疗癌症，特别是黑素瘤，骨髓瘤，小细胞肺癌，胸腺淋巴瘤，T细胞淋巴瘤，B细胞淋巴瘤，骨肉瘤和急性T细胞白血病的组合物和方法。说明性组合物包括一种或多种编码这种抗神经节苷脂抗体的抗神经节苷脂抗体和多核苷酸。这些抗体可以是例如仓鼠抗体，嵌合人/仓鼠抗体或人源化抗体。所公开的组合物可用于例如治疗癌症，并可用于诱导癌细胞中的细胞凋亡。

33. 发明申请

US20070030001A1 Resonant magnetometer device 有权
标题翻译：共振磁力计装置
公开(公告)号：US20070030001A1
公开(公告)日：2007-02-08
申请号：US10572379
申请日：2004-09-21
申请人： Kevin Brunson , David King
发明人： Kevin Brunson , David King
IPC分类号： G01R15/18 , G01R33/04 , G01R33/00
CPC分类号： G01R33/0283 , G01R33/0286
摘要： A resonant magnetometer (20) is described that comprises a substrate having an member (26) and means for passing an alternating current (AC) through said oscillatory member (26). The magnetometer is characterised in that driving means (46,48) are also provided to impart a magnetic field independent oscillatory force to said oscillatory member (26). A micro-electromechanical systems (MEMS) implementation of the magnetometer is described.
摘要翻译：描述了包括具有构件（26）的衬底和用于使交流（AC）通过所述振荡构件（26）的装置的谐振磁力计（20）。磁力计的特征在于，还提供驱动装置（46,48）以向所述振荡构件（26）施加与磁场无关的振荡力。描述了磁力计的微机电系统（MEMS）实现。

34. 发明申请

US20060263374A1 Antibodies to treat cancer 审中-公开
标题翻译：治疗癌症的抗体
公开(公告)号：US20060263374A1
公开(公告)日：2006-11-23
申请号：US11497642
申请日：2006-08-01
申请人： Gary Fanger , Neil Fanger , David King , Marc Retter , Kenneth Rock
发明人： Gary Fanger , Neil Fanger , David King , Marc Retter , Kenneth Rock
IPC分类号： A61K39/395 , C07K16/30 , C07K16/46
CPC分类号： C07K16/30 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/73 , C07K2317/732
摘要： Compositions and methods for the treatment of cancer, particularly melanoma, myeloma, small cell lung cancer, thymic lymphoma, T-cell lymphoma, B-cell lymphoma, osteosarcoma, and acute T-cell leukemia, are disclosed. Illustrative compositions include one or more anti-ganglioside antibodies and polynucleotides that encode such anti-ganglioside antibodies. These antibodies may be for example, hamster antibodies, chimeric human/hamster antibodies, or humanized antibodies. The disclosed compositions are useful, for example, in the treatment of cancer and can be used to induce apoptosis in a cancer cell.
摘要翻译：公开了用于治疗癌症，特别是黑素瘤，骨髓瘤，小细胞肺癌，胸腺淋巴瘤，T细胞淋巴瘤，B细胞淋巴瘤，骨肉瘤和急性T细胞白血病的组合物和方法。说明性组合物包括一种或多种编码这种抗神经节苷脂抗体的抗神经节苷脂抗体和多核苷酸。这些抗体可以是例如仓鼠抗体，嵌合人/仓鼠抗体或人源化抗体。所公开的组合物可用于例如治疗癌症，并可用于诱导癌细胞中的细胞凋亡。

35. 发明申请

US20060233800A1 Biological products 有权
公开(公告)号：US20060233800A1
公开(公告)日：2006-10-19
申请号：US11374231
申请日：2006-03-13
申请人： Diljeet Athwal , Derek Brown , Andrew Weir , Andrew Popplewell , Andrew Chapman , David King
发明人： Diljeet Athwal , Derek Brown , Andrew Weir , Andrew Popplewell , Andrew Chapman , David King
IPC分类号： A61K39/395 , C07K16/24 , C07K16/46
CPC分类号： C07K16/241 , A61K47/6845 , A61K47/6875 , A61K2039/505 , C07K2317/24 , C07K2317/565
摘要： There is disclosed antibody molecules containing at least one CDR derived from a mouse monoclonal antibody having specificity for human TNFα. There is also disclosed a CDR grafted antibody wherein at least one of the CDRs is a hybrid CDR. Further disclosed are DNA sequences encoding the chains of the antibody molecules, vectors, transformed host cells and uses of the antibody molecules in the treatment of diseases mediated by TNFα.

36. 发明申请

US20060103755A1 Focusing mechanism for a vision detector 失效
标题翻译：一种视觉检测器的聚焦机制
公开(公告)号：US20060103755A1
公开(公告)日：2006-05-18
申请号：US10991601
申请日：2004-11-18
申请人： George Costigan , Steven Goodspeed , David King , Robert Tremblay , John Keating , Brian Phillips , James Hoffmaster
发明人： George Costigan , Steven Goodspeed , David King , Robert Tremblay , John Keating , Brian Phillips , James Hoffmaster
IPC分类号： H04N5/225
CPC分类号： H04N5/2254 , H04N5/2252 , H04N5/2256
摘要： A machine vision image acquisition system is provided with a housing or enclosure that protects the acquisition system components from an industrial environment. The machine vision image acquisition system has a focusing mechanism that can be actuated externally to the housing. The focusing mechanism uses a gear drive to transmit externally actuated focus adjustments to the optical components of the acquisition system.
摘要翻译：机器视觉图像采集系统设置有保护采集系统组件免受工业环境的外壳或外壳。机器视觉图像采集系统具有可以从壳体外部致动的聚焦机构。聚焦机构使用齿轮传动器将外部激活的聚焦调节传送到采集系统的光学部件。

37. 发明授权

US07029631B2 Apparatus for improved light collection 有权
标题翻译：用于改进光采集的装置
公开(公告)号：US07029631B2
公开(公告)日：2006-04-18
申请号：US10126153
申请日：2002-04-19
申请人： Leslie Leonard , David King
发明人： Leslie Leonard , David King
IPC分类号： G01N21/64
CPC分类号： G01N21/645 , G01N2021/6439 , G01N2021/6469 , G01N2021/6482
摘要： An apparatus for enhancing the collection of optical signals comprises a waveguide, which comprises a structure in a channel adapted for the flow of assay fluid. In one embodiment, fluorophore is coupled to a surface of the structure, where the fluorophore has a receptor for an analyte (ligand) in the assay fluid and the structure is adapted to transmit optical signals from the fluorophore to a detector that is adapted to detect optical signals from the fluorophore coupled to the waveguide.
摘要翻译：用于增强光学信号收集的装置包括波导，其包括适于测定流体流动的通道中的结构。在一个实施方案中，荧光团耦合到结构的表面，其中荧光团具有分析流体中分析物（配体）的受体，并且该结构适于将光信号从荧光团传输到适于检测的检测器来自耦合到波导的荧光团的光信号。

38. 发明申请

US20060066681A1 Power and ground buss layout for reduced substrate size 有权
标题翻译：电源和接地总线布局，以减小基板尺寸
公开(公告)号：US20060066681A1
公开(公告)日：2006-03-30
申请号：US10956939
申请日：2004-09-30
申请人： David King , Kristi Rowe
发明人： David King , Kristi Rowe
IPC分类号： B41J2/05
CPC分类号： B41J2/04541 , B41J2/04548 , B41J2/04563 , B41J2/0458 , B41J2/14072 , B41J2/14129
摘要： A semiconductor substrate for a micro-fluid ejection device. The substrate includes plurality of micro-fluid ejection actuators disposed adjacent a fluid supply slot in the semiconductor substrate. A plurality of power transistors, occupying a power transistor active area of the substrate, are disposed adjacent the ejection actuators and are connected through a first metal conductor layer to the ejection actuators. An array of logic circuits, occupying a logic circuit area of the substrate, is disposed adjacent the plurality of power transistors and is connected through a polysilicon conductor layer to the power transistors. A power conductor and a ground conductor for the ejection actuators is routed in a second metal conductor layer. The power conductor overlaps at least a portion of the power transistor active area of the substrate and the ground conductor overlaps at least a portion of the logic circuit area of the substrate.
摘要翻译：一种用于微流体喷射装置的半导体衬底。衬底包括邻近半导体衬底中的流体供应槽设置的多个微流体喷射致动器。占据基板的功率晶体管有源区的多个功率晶体管被设置在喷射致动器附近，并且通过第一金属导体层连接到喷射致动器。占据基板的逻辑电路区域的逻辑电路阵列被布置成与多个功率晶体管相邻，并且通过多晶硅导体层连接到功率晶体管。用于喷射致动器的电源导体和接地导体在第二金属导体层中布线。电源导体与衬底的功率晶体管有源区域的至少一部分重叠，并且接地导体与衬底的逻辑电路区域的至少一部分重叠。

39. 发明申请

US20050247552A1 Devices with extended area structures for mass transfer processing of fluids 有权
标题翻译：具有扩展区域结构的装置用于流体的传质处理
公开(公告)号：US20050247552A1
公开(公告)日：2005-11-10
申请号：US11061237
申请日：2005-02-18
申请人： Ward TeGrotenhuis , Robert Wegeng , Greg Whyatt , David King , Kriston Brooks , Victoria Stenkamp
发明人： Ward TeGrotenhuis , Robert Wegeng , Greg Whyatt , David King , Kriston Brooks , Victoria Stenkamp
IPC分类号： B01J8/04 , B01J19/00
CPC分类号： B01J19/0093 , B01J2219/00822 , B01J2219/00835 , B01J2219/00844 , B01J2219/00858 , B01J2219/00873 , B01J2219/00889 , B01J2219/00905 , B01J2219/00918 , B01J2219/00921 , C01B3/384 , C01B3/48 , C01B2203/0233 , C01B2203/0283 , C01B2203/044 , C01B2203/047 , C01B2203/066 , C01B2203/0822 , C01B2203/0827 , C01B2203/1288 , C01B2203/148 , C01B2203/1614 , C01B2203/1647 , Y02P20/128
摘要： A microchannel device includes several mass transfer microchannels to receive a fluid media for processing at least one heat transfer microchannel in fluid communication with a heat transfer fluid defined by a thermally conductive wall, and at several thermally conductive fins each connected to the wall and extending therefrom to separate the mass transfer microchannels from one another. In one form, the device may optionally include another heat transfer microchannel and corresponding wall that is positioned opposite the first wall and has the fins and the mass transfer microchannels extending therebetween.
摘要翻译：微通道装置包括几个传质微通道，用于接收流体介质，用于处理至少一个与由导热壁限定的传热流体流体连通的传热微通道，以及各自连接到壁并从其延伸的多个导热翅片以将质量传递微通道彼此分开。在一种形式中，该装置可以可选地包括另一个传热微通道和与第一壁相对定位的相应的壁，并且具有在其间延伸的翅片和传质微通道。

40. 发明申请

US20050242334A1 Guardrail support, attachment, and positioning block 有权
标题翻译：护栏支撑，附件和定位块
公开(公告)号：US20050242334A1
公开(公告)日：2005-11-03
申请号：US11081821
申请日：2005-03-16
申请人： David King
发明人： David King
IPC分类号： A01K3/00 , E01F15/04
CPC分类号： E01F15/0438
摘要： A guardrail support, attachment and positioning block used to space guardrails from support posts is disclosed. The positioning or spacer block is a generally rectangular block having corded-out cavities to reduce weight and tabs or projections for cooperatively engaging the sides and top of a support post as well as the edges of the guardrail during roadway safety barrier system installation. Webbing within one or more of the cavities may be used for additional structural support. To optimize the strength to weight characteristics of the spacer block, the spacer block may be formed by low-pressure injection molding. The spacer block may also be formed from virgin and/or recycled plastic material and/or include virgin or recycled rubber material, such as that obtained from the regrind of used tires, and/or another elastomeric materials from other sources.
摘要翻译：公开了一种用于将护栏用于支撑柱的护栏支撑，附接和定位块。定位或间隔块是一个大致矩形的块体，具有用于减轻重量的带有线的空腔并且用于在道路安全屏障系统安装期间配合地接合支撑柱的侧面和顶部以及护栏的边缘。在一个或多个空腔内的织带可以用于附加的结构支撑。为了优化间隔块的强度与重量特性，可以通过低压注射成型形成间隔块。间隔块也可以由未加工的和/或再循环的塑料材料形成，和/或包括原始或再循环的橡胶材料，例如从旧轮胎的再研磨得到的橡胶材料和/或来自其他来源的其它弹性体材料。

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