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    • 35. 发明授权
    • Laser dermatology with feedback control
    • 激光皮肤科与反馈控制
    • US6015404A
    • 2000-01-18
    • US759036
    • 1996-12-02
    • Gregory AltshulerAndrei V. Erofeev
    • Gregory AltshulerAndrei V. Erofeev
    • A61B17/00A61B18/00A61B18/20A61N5/06
    • A61B18/203A61B2017/00057A61B2017/00106A61B2018/00005A61B2018/00452A61B2018/00476
    • Method and apparatus are provided for use with systems applying laser energy to treat a selected dermatology problem. The method and apparatus protect skin not under treatment in skin regions affected by the laser by detecting, with a suitable sensor, at least a selected parameter in the skin region affected by the delivered laser energy and performing a control function to effect the desired protection by use of a feedback mechanism which is operative in response to an output from the sensor. For some embodiments, two laser pulses may be utilized, which pulses are spaced by a time which is preferably greater than the thermal relaxation time for affected regions not under treatment, for example an epidermis through which the energy is passed to an area under treatment, but is less than the thermal relaxation time of the area under treatment. The first of the pulses serves as a prediagnosis pulse which is clearly below the damage threshold for protected areas, with the sensor output for the first pulse being utilized to control at least one parameter of the second pulse.
    • 提供了与应用激光能量以处理选定的皮肤病学问题的系统一起使用的方法和装置。 所述方法和装置通过用合适的传感器检测受所传送的激光能量影响的皮肤区域中的至少一个选定参数,并且通过检测由所传送的激光能量产生的所需保护来执行控制功能来保护受激光影响的皮肤区域中的皮肤不受治疗 使用响应于来自传感器的输出操作的反馈机构。 对于一些实施例,可以使用两个激光脉冲,这些脉冲间隔一段时间,该时间优选地大于未处理的受影响区域的热松弛时间,例如通过该表皮将能量传递到处理区域的表皮, 但小于处理区域的热松弛时间。 脉冲中的第一个用作预定义脉冲,其明显低于受保护区域的损伤阈值,第一脉冲的传感器输出用于控制第二脉冲的至少一个参数。
    • 36. 发明申请
    • Method And Apparatus For Improved Vascular Related Treatment
    • 改善血管相关治疗的方法和装置
    • US20090149844A1
    • 2009-06-11
    • US12210427
    • 2008-09-15
    • Gregory AltshulerMichael Z. Smirnov
    • Gregory AltshulerMichael Z. Smirnov
    • A61B18/18A61N5/06
    • A61B18/203A61B2018/00452A61B2018/00458A61B2018/2075
    • Methods and apparatus are provided for selectively heating blood vessels in a patients skin to effect a desired dermatological (medical or cosmetic) treatment. For shallow vessels, particularly plexus vessels and superficial vessels/veins, radiation is applied to the vessels involved in the treatment which includes substantial radiation in a blue band of approximately 380-450 nm. The invention also involves maximizing the radiation used for which the safety radio for the area being treated is greater then one and minimizing the radiation used for which the safety ratio is less then one. This generally involves, depending on the blood vessel involved in the treatment and the patient's skin type, using radiation in one or more of a blue, green-yellow and near infrared wavelength band and filtering out radiation at other wavelengths, including radiation between the wavelength bands used.
    • 提供了用于选择性加热患者皮肤中的血管以实现期望的皮肤病学(医学或美容)治疗的方法和装置。 对于浅血管,特别是神经血管和浅表血管/静脉,辐射被施加到涉及治疗的血管,其包括大约380-450nm的蓝色波段的实质辐射。 本发明还涉及最大化所使用的辐射,其中被处理区域的安全无线电装置大于一个,并使安全比小于1的辐射最小化。 这通常涉及根据治疗中涉及的血管和患者的皮肤类型,使用蓝色,绿色 - 黄色和近红外波长带中的一种或多种的辐射并滤出其它波长的辐射,包括在波长 使用乐队。
    • 37. 发明申请
    • METHODS AND APPARATUS FOR PERFORMING PHOTOBIOSTIMULATION
    • 用于进行光合作用的方法和装置
    • US20080033516A1
    • 2008-02-07
    • US11866770
    • 2007-10-03
    • Gregory AltshulerIlya YaroslavskyMichail PankratovDov Gal
    • Gregory AltshulerIlya YaroslavskyMichail PankratovDov Gal
    • A61B18/18
    • A61N5/0616A61B2017/00057A61F7/00A61N5/0601A61N5/062
    • The present invention provides methods and devices for modulating the efficacy and/or increasing the efficiency of treatment of disease and/or cosmetic conditions through photobiostimulation combined with heating and/or cooling of the treatment region. In one aspect, methods and devices of the present invention are directed to modulating the efficacy of photobiostimulation in a target region by controlling the temperature in the region and/or its surrounding volume. According to some aspects of the present invention, tissue is heated such that biostimulation is applied to tissue that is hyperthermic. Alternatively, portions of the target region can be cooled to selectively target biostimulation to a specific region at a desired depth below the skin surface. A feedback mechanism is also provided so that the temperature of the target region can be selectively and accurately controlled.
    • 本发明提供了通过光热刺激与加热和/或冷却治疗区域来调节治疗疾病和/或美容条件的功效和/或提高效率的方法和装置。 在一个方面,本发明的方法和装置旨在通过控制区域和/或其周围体积中的温度来调节靶区域中光沸石的功效。 根据本发明的一些方面,加热组织使得生物刺激被施加到高热的组织。 或者,可以将目标区域的部分冷却以选择性地将生物刺激定位到皮肤表面下方所需深度的特定区域。 还提供了反馈机构,使得可以选择性和精确地控制目标区域的温度。