专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

31. 发明授权

US08208995B2 Method and apparatus for imaging of vessel segments 有权
标题翻译：用于血管段成像的方法和装置
公开(公告)号：US08208995B2
公开(公告)日：2012-06-26
申请号：US11211483
申请日：2005-08-24
申请人： Guillermo J. Tearney , Milen Shishkov , Brett Eugene Bouma
发明人： Guillermo J. Tearney , Milen Shishkov , Brett Eugene Bouma
IPC分类号： A61B6/00
CPC分类号： A61B5/6852 , A61B5/0062 , A61B5/0066 , A61B5/0084 , A61B5/02007
摘要： An apparatus, method and software arrangement for imaging a surface of a structure that is in contact with an opaque fluid is provided. The apparatus includes an article of manufacture (e.g., a housing), a fluid delivery arrangement and an imaging arrangement. The housing includes an aperture formed in the article of manufacture. The fluid delivery arrangement is configured to deliver a volume of substantially transparent fluid to the aperture formed in the housing. The imaging arrangement is configured to image the surface of the structure using an imaging modality after the volume of the transparent fluid is delivered to the aperture, wherein the imaging arrangement and/or the article of manufacture is translated along the surface of the structure while imaging the surface of the structure.
摘要翻译：提供了一种用于对与不透明流体接触的结构的表面进行成像的装置，方法和软件装置。该装置包括制品（例如，壳体），流体输送装置和成像装置。壳体包括形成在制品中的孔。流体输送装置构造成将一定体积的基本上透明的流体输送到形成在壳体中的孔。成像装置被配置为在将透明流体的体积传送到孔之后使用成像模态来对结构的表面进行成像，其中成像装置和/或制品在结构的表面上被平移，而成像结构的表面。

32. 发明申请

US20110275899A1 SPECTRALLY ENCODED MINIATURE ENDOSCOPIC IMAGING PROBE 审中-公开
标题翻译：光谱编码微型内窥镜成像探头
公开(公告)号：US20110275899A1
公开(公告)日：2011-11-10
申请号：US13187106
申请日：2011-07-20
申请人： Guillermo J. Tearney , Brett Eugene Bouma , Milen Stefanov Shishkov , Jonathan Jay Rosen
发明人： Guillermo J. Tearney , Brett Eugene Bouma , Milen Stefanov Shishkov , Jonathan Jay Rosen
IPC分类号： A61B1/06
CPC分类号： A61B5/0059 , A61B1/00096 , A61B1/0017 , A61B1/043 , A61B1/07 , A61B5/0062 , A61B5/0071 , A61B5/0084 , G02B21/0036 , G02B21/0048 , G02B21/0064
摘要： A spectrally encoded endoscopic probe having high resolution and small diameter comprising at least one flexible optical fiber; an energy source; a grating through which said energy is transmitted such that the energy spectrum is dispersed; a lens for focusing the dispersed energy spectrum onto a sample such that the impingement spot for each wavelength is a separate position on the sample, the wavelength spectrum defining a wavelength encoded axis; means for mechanically scanning the sample with focused energy in a direction perpendicular to the wavelength encoded axis; a means for receiving energy reflected from the sample; and, a means for detecting the received reflected energy. The probe grating and lens delivers a beam of multi-spectral light having spectral components extending in one dimension across a target region and which is moved to scan in another direction. The reflected spectrum is measured to provide two dimensional imaging of the region.
摘要翻译：一种具有高分辨率和小直径的光谱编码内窥镜探针，包括至少一个柔性光纤; 能源; 所述能量通过所述光栅传播，使得能谱被分散; 用于将分散的能谱聚焦到样品上的透镜，使得每个波长的冲击点是样品上的分离位置，所述波长谱定义波长编码轴; 用于在垂直于波长编码轴的方向上以聚焦能量机械扫描样品的装置; 用于接收样品反射的能量的方法; 以及用于检测所接收的反射能量的装置。探测光栅和透镜提供具有在一个维度上延伸穿过目标区域并且被移动以沿另一个方向扫描的光谱分量的多光谱光束。测量反射光谱以提供该区域的二维成像。

33. 发明授权

US07995210B2 Devices and arrangements for performing coherence range imaging using a common path interferometer 有权
标题翻译：使用公共路径干涉仪进行相干距离成像的装置和装置
公开(公告)号：US07995210B2
公开(公告)日：2011-08-09
申请号：US11285301
申请日：2005-11-21
申请人： Guillermo J. Tearney , Brett Eugene Bouma
发明人： Guillermo J. Tearney , Brett Eugene Bouma
IPC分类号： G01B9/02 , G01B11/02
CPC分类号： A61B5/6852 , A61B5/0066 , G01B9/02004 , G01B9/02044 , G01B9/0205 , G01B9/02057 , G01B9/02091 , G01B2290/70 , G01D5/35303 , G01N21/4795
摘要： Devices, arrangements and apparatus adapted to propagate at least one electro-magnetic radiation are provided. In particular, a probe housing, a sample arm section and a reference arm section can be included. For example, the sample arm section can be at least partially situated within the probe housing, and configured to propagate a first portion of the electro-magnetic radiation that is intended to be forwarded to a sample. The reference arm section can be at least partially situated within the probe housing, and configured to propagate a second portion of the electro-magnetic radiation that is intended to be forwarded to a reference. In addition or as an alternative, an interferometer may be situated within the probe housing. The first and second portions may travel along substantially the same paths, and the electro-magnetic radiation can be generated by a narrowband light source that has a tunable center wavelength. Further, the first and second portions may be at least partially transmitted via at least one optical fiber. A splitting arrangement may be provided which splits the electro-magnetic radiation into the first and second portions, and positioned closer to the sample than to the source of the electro-magnetic radiation, and the first and second portions may be adapted to propagate in different directions. An apparatus may be provided that is configured to control an optical path length of the second portion.
摘要翻译：提供适于传播至少一个电磁辐射的装置，装置和装置。特别地，可以包括探针壳体，样品臂部分和参考臂部分。例如，样品臂部分可以至少部分地位于探针壳体内，并且被配置为传播旨在被转发到样品的电磁辐射的第一部分。参考臂部分可以至少部分地位于探针壳体内，并且被配置为传播旨在被转发到参考的电磁辐射的第二部分。另外或作为替代，干涉仪可以位于探针外壳内。第一和第二部分可以沿着基本上相同的路径行进，并且电磁辐射可以由具有可调谐中心波长的窄带光源产生。此外，第一和第二部分可以经由至少一根光纤至少部分地传输。可以提供分裂装置，其将电磁辐射分裂成第一和第二部分，并且比电磁辐射源更靠近样品定位，并且第一和第二部分可适于以不同的方式传播方向。可以提供被配置为控制第二部分的光路长度的装置。

34. 发明授权

US07859679B2 System, method and arrangement which can use spectral encoding heterodyne interferometry techniques for imaging 有权
标题翻译：可以使用频谱编码外差干涉测量技术进行成像的系统，方法和布置
公开(公告)号：US07859679B2
公开(公告)日：2010-12-28
申请号：US11445131
申请日：2006-05-31
申请人： Brett Eugene Bouma , Guillermo J. Tearney , Dvir Yelin , Seok-Hyun Yun
发明人： Brett Eugene Bouma , Guillermo J. Tearney , Dvir Yelin , Seok-Hyun Yun
IPC分类号： G01B9/02 , G01B11/02
CPC分类号： G01N21/4795 , A61B5/0066 , A61B5/0084 , A61B5/7257
摘要： Systems, arrangements and methods for obtaining three-dimensional imaging data are provided. For example, a broadband light source can provide a particular radiation. A first electro-magnetic radiation can be focused and diffracted, and then provided to at least one sample to generate a spectrally-encoded line. A second electro-magnetic radiation may be provided to a reference, which may include a double-pass rapidly-scanning optical delay, where the first and second electro-magnetic radiations can be based on the particular radiation. An interference between a third electro-magnetic radiation (associated with the first electro-magnetic radiation) and a fourth electro-magnetic radiation (associated with the second electro-magnetic radiation) can be detected. The spectrally-encoded line may be scanned over the sample in a direction approximately perpendicular to the line. Image data containing three-dimensional information can then be obtained based on the interference. The exemplary imaging methods and systems can be used in a small fiber optic or endoscopic probe.
摘要翻译：提供了用于获得三维成像数据的系统，布置和方法。例如，宽带光源可以提供特定的辐射。可以将第一电磁辐射聚焦和衍射，然后提供给至少一个样品以产生光谱编码的线。可以将第二电磁辐射提供给参考，其可以包括双遍快速扫描光学延迟，其中第一和第二电磁辐射可以基于特定辐射。可以检测第三电磁辐射（与第一电磁辐射相关联）和第四电磁辐射（与第二电磁辐射相关联）之间的干扰。光谱编码的线可以在大致垂直于线的方向上扫描样品。然后可以基于干扰获得包含三维信息的图像数据。示例性的成像方法和系统可以用于小型光纤或内窥镜探针。

35. 发明授权

US07796270B2 Systems and methods for generating data based on one or more spectrally-encoded endoscopy techniques 有权
标题翻译：基于一个或多个频谱编码的内窥镜技术产生数据的系统和方法
公开(公告)号：US07796270B2
公开(公告)日：2010-09-14
申请号：US11621694
申请日：2007-01-10
申请人： Dvir Yelin , Seok-Hyun Yun , Brett Eugene Bouma , Guillermo J Tearney
发明人： Dvir Yelin , Seok-Hyun Yun , Brett Eugene Bouma , Guillermo J Tearney
IPC分类号： G01B9/02 , G01J3/45 , G01N21/00
CPC分类号： G01N21/4795 , A61B5/0066 , A61B5/6852 , A61B5/7257 , A61B5/726 , G01B9/02002 , G01B9/02036 , G01B9/02037 , G01B9/02044 , G01B9/02091 , G01N21/359 , G01N2021/1782 , G01N2021/1787 , G01N2021/3595
摘要： Exemplary systems and methods for generating data associated with at least one portion of a sample can be provided. For example, according to one exemplary embodiment of such systems and methods, it is possible to provide a particular radiation using at least one first arrangement. The particular radiation can include at least one first electro-magnetic radiation directed to at least one sample and at least one second electro-magnetic radiation directed to a reference arrangement. The first radiation and/or the second radiation can comprise a plurality of wavelengths. The first electro-magnetic radiation can be spectrally dispersed along at least one portion of the sample. The second electro-magnetic radiation measured at two or more different lengths of the reference arrangement with respect to the first arrangement. Data can be generated which is associated with the first and second electro-magnetic radiations obtained at the two different lengths using at least one second arrangement which comprises a spectrometer arrangement.
摘要翻译：可以提供用于产生与样品的至少一部分相关联的数据的示例性系统和方法。例如，根据这样的系统和方法的一个示例性实施例，可以使用至少一个第一布置来提供特定的辐射。特定的辐射可以包括被引导至至少一个样品的至少一个第一电磁辐射和指向参考装置的至少一个第二电磁辐射。第一辐射和/或第二辐射可以包括多个波长。第一电磁辐射可沿样品的至少一部分光谱分散。在参考装置的两个或多个不同长度处相对于第一装置测量的第二电磁辐射。可以生成与使用包括光谱仪布置的至少一个第二布置在两个不同长度获得的第一和第二电磁辐射相关联的数据。

36. 发明授权

US07742173B2 Methods, arrangements and systems for polarization-sensitive optical frequency domain imaging of a sample 有权
标题翻译：样品的偏振敏感光学频域成像的方法，布置和系统
公开(公告)号：US07742173B2
公开(公告)日：2010-06-22
申请号：US11697012
申请日：2007-04-05
申请人： Seok-Hyun Yun , Johannes F. De Boer , Guillermo J. Tearney , Brett Eugene Bouma
发明人： Seok-Hyun Yun , Johannes F. De Boer , Guillermo J. Tearney , Brett Eugene Bouma
IPC分类号： G01B9/02
CPC分类号： G01N21/4795 , G01B9/02002 , G01B9/02004 , G01B9/02011 , G01B9/02091 , G01B2290/70
摘要： Arrangements and methods are provided for obtaining data associated with a sample. For example, at least one first electro-magnetic radiation can be provided to a sample and at least one second electro-magnetic radiation can be provided to a reference (e.g., a non-reflective reference). A frequency of such radiation(s) can repetitively vary over time with a first characteristic period. In addition, a polarization state of the first electro-magnetic radiation, the second electro-magnetic radiation, a third electro-magnetic radiation (associated with the first radiation) or a fourth electro-magnetic radiation (associated with the second radiation) can repetitively vary over time with a second characteristic period which is shorter than the first period. The data for imaging at least one portion of the sample can be provided as a function of the polarization state. In addition or alternatively, the third and fourth electro-magnetic radiations can be combined so as to determine an axial reflectance profile of at least one portion of the sample.
摘要翻译：提供了用于获取与样本相关的数据的安排和方法。例如，可以向样品提供至少一个第一电磁辐射，并且可以向参考（例如，非反射参考）提供至少一个第二电磁辐射。这种辐射的频率可以在第一特征周期内随时间重复地变化。此外，第一电磁辐射，第二电磁辐射，第三电磁辐射（与第一辐射相关联）或第四电磁辐射（与第二辐射相关联）的极化状态可以重复地随着时间而变化，其具有比第一周期短的第二特征周期。用于成像至少一部分样品的数据可以作为偏振态的函数提供。另外或替代地，可以组合第三和第四电磁辐射，以便确定样品的至少一部分的轴向反射率分布。

37. 发明申请

US20100094576A1 APPARATUS AND METHOD FOR RANGING AND NOISE REDUCTION OF LOW COHERENCE INTERFEROMETRY LCI AND OPTICAL COHERENCE TOMOGRAPHY OCT SIGNALS BY PARALLEL DETECTION OF SPECTRAL BANDS 有权
标题翻译：通过平行检测光谱仪的低相干干涉LCI和光学相干TOMOGRAPHY OCT信号的范围和噪声降低的装置和方法
公开(公告)号：US20100094576A1
公开(公告)日：2010-04-15
申请号：US12570443
申请日：2009-09-30
申请人： Johannes F. de Boer , Guillermo J. Tearney , Brett Eugene Bouma
发明人： Johannes F. de Boer , Guillermo J. Tearney , Brett Eugene Bouma
IPC分类号： G01B9/02 , G06F19/00
CPC分类号： G01B9/02007 , A61B5/0059 , A61B5/0066 , A61B5/7257 , G01B9/02008 , G01B9/0201 , G01B9/02032 , G01B9/02044 , G01B9/02045 , G01B9/02079 , G01B9/0209 , G01B9/02091 , G01B2290/45 , G01N21/4795
摘要： Apparatus and method for increasing the sensitivity in the detection of optical coherence tomography and low coherence interferometry (“LCI”) signals by detecting a parallel set of spectral bands, each band being a unique combination of optical frequencies. The LCI broad bandwidth source is split into N spectral bands. The N spectral bands are individually detected and processed to provide an increase in the signal-to-noise ratio by a factor of N. Each spectral band is detected by a separate photo detector and amplified. For each spectral band the signal is band pass filtered around the signal band by analog electronics and digitized, or, alternatively, the signal may be digitized and band pass filtered in software. As a consequence, the shot noise contribution to the signal is reduced by a factor equal to the number of spectral bands. The signal remains the same. The reduction of the shot noise increases the dynamic range and sensitivity of the system.
摘要翻译：通过检测并行的一组光谱带来增加光学相干断层扫描和低相干干涉测量（“LCI”）信号的灵敏度的装置和方法，每个频带是光频率的唯一组合。 LCI宽带宽源分为N个频谱带。 N个光谱带被单独检测和处理，以使信噪比增加N倍。每个光谱带由单独的光检测器检测并被放大。对于每个光谱带，信号通过模拟电子装置在信号带周围进行带通滤波，并且被数字化，或者，信号可以被数字化并且在软件中进行带通滤波。结果，对信号的散粒噪声贡献减小了等于光谱带数的因子。信号保持不变。喷射噪声的降低增加了系统的动态范围和灵敏度。

38. 发明申请

US20070236700A1 METHODS, ARRANGEMENTS AND SYSTEMS FOR POLARIZATION-SENSITIVE OPTICAL FREQUENCY DOMAIN IMAGING OF A SAMPLE 有权
标题翻译：方法，用于样品的偏振光敏频域成像的安排和系统
公开(公告)号：US20070236700A1
公开(公告)日：2007-10-11
申请号：US11697012
申请日：2007-04-05
申请人： Seok-Hyun Yun , Johannes F. De Boer , Guillermo J. Tearney , Brett Eugene Bouma
发明人： Seok-Hyun Yun , Johannes F. De Boer , Guillermo J. Tearney , Brett Eugene Bouma
IPC分类号： G01B9/02
CPC分类号： G01N21/4795 , G01B9/02002 , G01B9/02004 , G01B9/02011 , G01B9/02091 , G01B2290/70
摘要： Arrangements and methods are provided for obtaining data associated with a sample. For example, at least one first electro-magnetic radiation can be provided to a sample and at least one second electro-magnetic radiation can be provided to a reference (e.g., a non-reflective reference). A frequency of such radiation(s) can repetitively vary over time with a first characteristic period. In addition, a polarization state of the first electro-magnetic radiation, the second electro-magnetic radiation, a third electro-magnetic radiation (associated with the first radiation) or a fourth electro-magnetic radiation (associated with the second radiation) can repetitively vary over time with a second characteristic period which is shorter than the first period. The data for imaging at least one portion of the sample can be provided as a function of the polarization state. In addition or alternatively, the third and fourth electro-magnetic radiations can be combined so as to determine an axial reflectance profile of at least one portion of the sample.
摘要翻译：提供了用于获取与样本相关的数据的安排和方法。例如，可以向样品提供至少一个第一电磁辐射，并且可以向参考（例如，非反射参考）提供至少一个第二电磁辐射。这种辐射的频率可以在第一特征周期内随时间重复地变化。此外，第一电磁辐射，第二电磁辐射，第三电磁辐射（与第一辐射相关联）或第四电磁辐射（与第二辐射相关联）的偏振状态可以重复地随着时间而变化，其具有比第一周期短的第二特征周期。用于成像至少一部分样品的数据可以作为偏振态的函数提供。另外或替代地，可以组合第三和第四电磁辐射，以便确定样品的至少一部分的轴向反射率分布。

39. 发明授权

US08965487B2 Process, system and software arrangement for measuring a mechanical strain and elastic properties of a sample 有权
标题翻译：用于测量样品的机械应变和弹性性能的工艺，系统和软件布置
公开(公告)号：US08965487B2
公开(公告)日：2015-02-24
申请号：US11211482
申请日：2005-08-24
申请人： Brett Eugene Bouma , Raymond C. Chan , Guillermo J. Tearney
发明人： Brett Eugene Bouma , Raymond C. Chan , Guillermo J. Tearney
IPC分类号： A61B5/02 , A61B5/00
CPC分类号： A61B5/0066 , A61B5/0059 , A61B5/02007
摘要： A system, process and software arrangement are provided to determining data associated with at least one structural change of tissue. In particular, a first optical coherence tomography (“OCT”) signal which contains first information regarding the tissue at a first stress level, and a second OCT signal which contains second information regarding the tissue at a second stress level are received. The first and second information are compared to produce comparison information. The data associated with the at least one structural change is determined as a function of the comparison information and further information associated with (i) at least one known characteristics of the tissue and/or (ii) characteristics of an OCT system. Further, at least one optical coherence tomography (“OCT”) signal which contains information regarding the tissue can be received, and the modulus of the tissue may be determined as a function of the received at least one OCT signal.
摘要翻译：提供系统，过程和软件布置以确定与组织的至少一个结构变化相关联的数据。特别地，接收包含关于第一应力水平的组织的第一信息的第一光学相干断层摄影（“OCT”）信号和包含关于第二应力水平的组织的第二信息的第二OCT信号。比较第一和第二信息以产生比较信息。与至少一个结构变化相关联的数据被确定为比较信息和与（i）组织的至少一个已知特征和/或（ii）OCT系统的特征相关联的进一步信息的函数。此外，可以接收包含关于组织的信息的至少一个光学相干断层摄影（“OCT”）信号，并且可以根据所接收的至少一个OCT信号来确定组织的模量。

40. 发明授权

US08922781B2 Arrangements, devices, endoscopes, catheters and methods for performing optical imaging by simultaneously illuminating and detecting multiple points on a sample 有权
标题翻译：用于通过同时照射和检测样品上的多个点来执行光学成像的装置，装置，内窥镜，导管和方法
公开(公告)号：US08922781B2
公开(公告)日：2014-12-30
申请号：US11288994
申请日：2005-11-29
申请人： Guillermo J. Tearney , Johannes F. de Boer , Brett Eugene Bouma
发明人： Guillermo J. Tearney , Johannes F. de Boer , Brett Eugene Bouma
IPC分类号： G01B9/02 , G02B21/00 , A61B5/00 , G02B23/24 , G02B23/26
CPC分类号： G02B23/2469 , A61B5/0066 , A61B5/0073 , A61B5/6852 , G01B9/02001 , G01B9/02091 , G02B21/0032 , G02B21/0056 , G02B23/2453 , G02B23/26
摘要： Devices, arrangements, endoscopes, catheters and methods adapted to propagate at least one electro-magnetic radiation are provided. In particular, a waveguide apparatus specifically configured may be utilized to split the electro-magnetic radiation into a plurality of beams that are intended to illuminate a biological sample, and impart a unique associated characteristic unto each of the beams. The beams may be intended to illuminate a biological sample at distinct locations, and impart a unique associated characteristic unto each of the beams. In addition, a control apparatus may be provided which is configured to control at least one of the fibers and which can be input to the fibers so as to modify the unique associated characteristics of the beams being propagated along the fibers, and thereby modify the characteristics of the distinct locations on the sample.
摘要翻译：提供了适于传播至少一个电磁辐射的装置，布置，内窥镜，导管和方法。特别地，可以使用专门配置的波导装置将电磁辐射分割成旨在照射生物样品的多个光束，并且向每个光束赋予独特的相关特征。光束可以用于在不同的位置照射生物样品，并且赋予每个光束唯一的相关特征。此外，可以提供控制装置，其被配置为控制光纤中的至少一个并且可以输入到光纤，以便改变沿着光纤传播的光束的独特相关特性，从而改变特性的样品上不同的位置。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式