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    • 35. 发明申请
    • Everting Heart Valve
    • 永恒心脏瓣膜
    • US20090264997A1
    • 2009-10-22
    • US12492512
    • 2009-06-26
    • Amr SalahiehUlrich R. HaugHans F. ValenciaRobert A. GeshliderTom SaulDwight P. MorejohnKenneth J. Michlitsch
    • Amr SalahiehUlrich R. HaugHans F. ValenciaRobert A. GeshliderTom SaulDwight P. MorejohnKenneth J. Michlitsch
    • A61F2/24
    • A61F2/2418A61F2/2412A61F2/2433A61F2/2436A61F2/2439A61F2220/0016A61F2220/0033A61F2220/005A61F2220/0058A61F2220/0075A61F2230/005A61F2230/0054A61F2230/0065A61F2230/0078
    • The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an expandable anchor configured for endovascular delivery to a vicinity of the patient's heart valve. In some embodiments, the replacement valve is adapted to wrap about the anchor, for example, by everting during endovascular deployment. In some embodiments, the replacement valve is not connected to expandable portions of the anchor. In some embodiments, the anchor is configured for active foreshortening during endovascular deployment. In some embodiments, the anchor includes expandable lip and skirt regions for engaging the patient's heart valve during deployment. In some embodiments, the anchor comprises a braid fabricated from a single strand of wire. In some embodiments, the apparatus includes a lock configured to maintain anchor expansion. The invention also includes methods for endovascularly replacing a patient's heart valve. In some embodiments, the method includes the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve, wrapping at least a portion of the replacement valve about the anchor, and expanding the anchor to a deployed configuration.
    • 本发明提供了用于血管内替代患者心脏瓣膜的方法和装置。 该装置包括置换瓣膜和可扩张锚固件,其可构造成用于血管内递送至患者心脏瓣膜附近。 在一些实施例中,替换瓣膜适于例如在血管内部署过程中绕过锚固件。 在一些实施例中,替换阀不连接到锚的可膨胀部分。 在一些实施例中,锚定构件用于在血管内部署过程中进行主动缩短。 在一些实施例中,锚固件包括用于在展开期间与患者的心脏瓣膜接合的可扩张唇缘和裙部区域。 在一些实施例中,锚固件包括由单股线制成的编织物。 在一些实施例中,该装置包括被配置成保持锚固扩展的锁。 本发明还包括用于血管内替代患者心脏瓣膜的方法。 在一些实施例中,该方法包括以下步骤:将置换瓣膜和可膨胀锚固件血管内输送到心脏瓣膜附近,将替代瓣膜的至少一部分围绕锚定件包裹,并将锚固件扩展至展开构造。