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31. 发明授权

US08091612B2 Method for manufacturing clad material and equipment for manufacturing the same 有权
标题翻译：复合材料的制造方法及其制造方法
公开(公告)号：US08091612B2
公开(公告)日：2012-01-10
申请号：US12095983
申请日：2006-12-07
申请人： Masayuki Takada , Yasuhiro Nishioka , Tomohiro Nishimura , Kenji Tokuda , Toshiki Ueda , Makoto Morishita , Takashi Inaba , Akihiro Tsuruno , Yoshinori Kato , Fumihiro Koshigoe , Masaki Tanigawa , Naoki Sakashita , Kenji Harada , Jitsuto Shikata , Masanori Ikeda
发明人： Masayuki Takada , Yasuhiro Nishioka , Tomohiro Nishimura , Kenji Tokuda , Toshiki Ueda , Makoto Morishita , Takashi Inaba , Akihiro Tsuruno , Yoshinori Kato , Fumihiro Koshigoe , Masaki Tanigawa , Naoki Sakashita , Kenji Harada , Jitsuto Shikata , Masanori Ikeda
IPC分类号： B22D11/00 , B22D11/12 , B22D11/126 , B22D19/16
CPC分类号： B32B3/00 , B22D11/007 , B23K20/04 , B23K35/22 , B23K35/40 , B23K2101/16 , B32B15/016 , C22C21/00 , C22F1/04 , Y10T428/12736 , Y10T428/12764 , Y10T428/12993
摘要： A method for manufacturing a clad material composed of a core material and one or more skin materials which are superposed on either one or both faces of the core material, includes a clad material preparation process where an ingot for core material is manufactured by melting and casting a metal, and an ingot for skin material is manufactured by melting and casting a different metal for skin material, without hot rolling. The ingot for skin material is superposed as a skin material at a predetermined position of either one or both faces of the ingot for core material and the superposed material is hot-rolled to manufacture a clad material.
摘要翻译：一种由芯材构成的复合材料和叠层在芯材的一面或两面上的一种或多种表皮材料的包覆材料的制造方法，包括：通过熔融铸造制造芯材用铸锭的复合材料制备方法金属和用于表皮材料的锭是通过熔化和铸造用于表皮材料的不同金属而不进行热轧而制造的。将表皮材料锭作为表皮材料叠置在用于芯材的锭的一个或两个面的预定位置，并且叠加的材料被热轧以制造包覆材料。

32. 发明申请

US20090071576A1 ALUMINUM ALLOY PLATE AND PROCESS FOR PRODUCING THE SAME 有权
标题翻译：铝合金板及其制造方法
公开(公告)号：US20090071576A1
公开(公告)日：2009-03-19
申请号：US11814124
申请日：2006-01-13
申请人： Makoto Morishita , Katsushi Matsumoto , Shigenobu Yasunaga , Takashi Inaba
发明人： Makoto Morishita , Katsushi Matsumoto , Shigenobu Yasunaga , Takashi Inaba
IPC分类号： C22F1/047 , C22C21/08
CPC分类号： B22D11/003 , B21B2003/001 , B22D11/0622 , B22D11/0682 , C22C21/06 , C22C21/08 , C22F1/047
摘要： The present invention provides an Al—Mg series alloy sheet of high-Mg with improved press formability and homogeneity which can be applied to automobile outer panels and inner panels. This is an Al—Mg series aluminum alloy sheet having 3.5 to 3 mm in thickness cast by twin-roll continuous casting and cold rolled, comprising over 8% but not more than 14% Mg, 1.0% or less Fe, and 3.5% or less Si with the remainder being Al and unavoidable impurities wherein the mean conductivity of the aluminum alloy sheet is in the range of at least 20 IACS % but less than 26 IACS %, the strength-ductility balance (tensile strength×total elongation) as a material property of the aluminum alloy sheet is 11000 (MPa %) or more, and the homogeneity and press formability of the sheet have been improved.
摘要翻译：本发明提供了可以应用于汽车外板和内板的具有改善的冲压成形性和均匀性的高Mg的Al-Mg系合金板。这是通过双辊连续铸造和冷轧铸造的厚度为3.5至3mm的Al-Mg系铝合金板，包含超过8％但不超过14％的Mg，1.0％或更少的Fe和3.5％或较少的Si，其余为Al和不可避免的杂质，其中铝合金板的平均导电率在至少20IACS％但小于26IACS％的范围内，作为材料性能的强度 - 延展性平衡（拉伸强度×总伸长率）的比例为11000（MPa％）以上，片材的均匀性和冲压成形性提高。

33. 发明申请

US20080306258A1 Cyclopropane compounds and pharmaceutical use thereof 审中-公开
标题翻译：环丙烷化合物及其药物用途
公开(公告)号：US20080306258A1
公开(公告)日：2008-12-11
申请号：US12149683
申请日：2008-05-06
申请人： Takashi Inaba , Julia Haas , Makoto Shiozaki , Nicole M. Littmann , Katsutaka Yasue , Steven W. Andrews , Atushi Sakai , Andrew M. Fryer , Takafumi Matsuo , Ellen R. Laird , Akira Suma , Yuichi Shinozaki , Yoshikazu Hori , Hiroto Imai , Tamotsu Negoro
发明人： Takashi Inaba , Julia Haas , Makoto Shiozaki , Nicole M. Littmann , Katsutaka Yasue , Steven W. Andrews , Atushi Sakai , Andrew M. Fryer , Takafumi Matsuo , Ellen R. Laird , Akira Suma , Yuichi Shinozaki , Yoshikazu Hori , Hiroto Imai , Tamotsu Negoro
IPC分类号： C07D243/08 , C07D413/14
CPC分类号： C07C311/29 , C07C311/13 , C07C311/20 , C07C311/22 , C07C311/46 , C07C2601/02 , C07C2601/14 , C07C2603/08 , C07C2603/18 , C07C2603/30 , C07D205/04 , C07D207/48 , C07D209/44 , C07D211/58 , C07D211/96 , C07D213/18 , C07D213/65 , C07D213/71 , C07D213/74 , C07D213/81 , C07D213/82 , C07D217/08 , C07D231/12 , C07D233/64 , C07D237/12 , C07D239/22 , C07D243/08 , C07D257/04 , C07D261/08 , C07D271/06 , C07D271/107 , C07D277/26 , C07D277/36 , C07D277/82 , C07D295/26 , C07D307/79 , C07D307/91 , C07D333/18 , C07D333/34 , C07D333/36 , C07D333/38 , C07D333/62 , C07D401/04 , C07D409/04 , C07D409/12 , C07D413/04 , C07D417/04 , C07D417/12 , C07D471/04 , C07D487/04 , C07D513/04
摘要： The present invention provides a compound having aggrecanase inhibitory activity and MMP-13 inhibitory activity, and useful as a therapeutic agent for osteoarthritis, rheumatoid arthritis and the like, more specifically, a cyclopropane compound of formula (1): wherein R1 is —(CH2)m—X—(CH2)n-A1 etc., wherein m and n are the same or different and each is 0 to 6, X is a single bond, etc. and A1 is a substituted C3-14 hydrocarbon ring group, etc.; R2 and R3 are the same or different and each is a hydrogen atom, —(CH2)p—X1—(CH2)q-A2, etc., wherein p and q are the same or different and each is 0 to 6, X1 is a single bond, etc. and A2 is an optionally substituted C3-14 hydrocarbon ring group, etc.; R4 is —CO2R9, etc., wherein R9 is a hydrogen atom, etc.; and R20 and R21 are the same or different and each is a hydrogen atom, —(CH2)m12—X12—(CH2)m12—R30 etc., wherein m12 and m12 are the same or different and each is 0 to 6, X12 is a single bond, etc. and R30 is a hydrogen atom, etc.; or a prodrug thereof or a pharmaceutically acceptable salt thereof.
摘要翻译：本发明提供具有聚集蛋白聚糖蛋白聚糖酶抑制活性和MMP-13抑制活性的化合物，可用作骨关节炎，类风湿性关节炎等的治疗剂，更具体而言，可以使用式（1）所示的环丙烷化合物：其中，R 1为 - （CH 2 ）mX-（CH2）n-A1等，其中m和n相同或不同，各自为0至6，X为单键等，而A1为取代的C3-14烃环基等。 ; R2和R3相同或不同，各自为氢原子， - （CH2）p-X1-（CH2）q-A2等，其中p和q相同或不同，各自为0至6，X1 是单键等，A2是任选取代的C 3-14烃环基等; R4是-CO 2 R 9等，其中R9是氢原子等; 和R 20和R 21相同或不同，各自为氢原子， - （CH 2）m 12 -X 12 - （CH 2）m 12 -R 30等，其中m12和m12相同或不同，各自为0至6，X12 是单键等，R30是氢原子等; 或其前药或其药学上可接受的盐。

34. 发明申请

US20080261994A1 CYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF 审中-公开
标题翻译：环丙沙星化合物及其药物用途
公开(公告)号：US20080261994A1
公开(公告)日：2008-10-23
申请号：US12016755
申请日：2008-01-18
申请人： Takashi INABA , Julia Hass , Makoto Shiozaki , Nicole M. Littmann , Katsutaka Yasue , Steven W. Andrews , Atushi Sakai , Andrew M. Fryer , Takafumi Matsuo , Ellen R. Laird , Akira Suma , Yuichi Shinozaki , Yoshikazu Hori , Hiroto Imai , Tamotsu Negoro
发明人： Takashi INABA , Julia Hass , Makoto Shiozaki , Nicole M. Littmann , Katsutaka Yasue , Steven W. Andrews , Atushi Sakai , Andrew M. Fryer , Takafumi Matsuo , Ellen R. Laird , Akira Suma , Yuichi Shinozaki , Yoshikazu Hori , Hiroto Imai , Tamotsu Negoro
IPC分类号： A61K31/496 , A61K31/4436 , A61K31/416 , C07D411/00 , C07D217/00 , C07D265/00 , C07D311/00 , A61P19/02
CPC分类号： C07C311/29 , C07C311/13 , C07C311/20 , C07C311/22 , C07C311/46 , C07C2601/02 , C07C2601/14 , C07C2603/08 , C07C2603/18 , C07C2603/30 , C07D205/04 , C07D207/48 , C07D209/44 , C07D211/58 , C07D211/96 , C07D213/18 , C07D213/65 , C07D213/71 , C07D213/74 , C07D213/81 , C07D213/82 , C07D217/08 , C07D231/12 , C07D233/64 , C07D237/12 , C07D239/22 , C07D243/08 , C07D257/04 , C07D261/08 , C07D271/06 , C07D271/107 , C07D277/26 , C07D277/36 , C07D277/82 , C07D295/26 , C07D307/79 , C07D307/91 , C07D333/18 , C07D333/34 , C07D333/36 , C07D333/38 , C07D333/62 , C07D401/04 , C07D409/04 , C07D409/12 , C07D413/04 , C07D417/04 , C07D417/12 , C07D471/04 , C07D487/04 , C07D513/04
摘要： The present invention provides a compound having aggrecanase inhibitory activity and MMP-13 inhibitory activity, and useful as a therapeutic agent for osteoarthritis, rheumatoid arthritis and the like, more specifically, a cyclopropane compound of formula (1): wherein R1 is —(CH2)m—X—(CH2)n-A1 etc., wherein m and n are the same or different and each is 0 to 6, X is a single bond, etc. and A1 is a substituted C3-14 hydrocarbon ring group, etc.; R2 and R3 are the same or different and each is a hydrogen atom, —(CH2)p—X1—(CH2)q-A2, etc., wherein p and q are the same or different and each is 0 to 6, X1 is a single bond, etc. and A2 is an optionally substituted C3-14 hydrocarbon ring group, etc.; R4 is —CO2R9, etc., wherein R9 is a hydrogen atom, etc.; and R20 and R21 are the same or different and each is a hydrogen atom, —(CH2)m12—X12—(CH2)m12—R30, etc., wherein m12 and m12 are the same or different and each is 0 to 6, X12 is a single bond, etc. and R30 is a hydrogen atom, etc.; or a prodrug thereof or a pharmaceutically acceptable salt thereof.
摘要翻译：本发明提供具有聚集蛋白聚糖蛋白聚糖酶抑制活性和MMP-13抑制活性的化合物，可用作骨关节炎，类风湿性关节炎等的治疗剂，更具体而言，可以使用式（1）的环丙烷化合物：其中R 1 是 - （CH 2）2 -X-（CH 2）n - SUP> 1等，其中m和n相同或不同，并且各自为0至6，X为单键等，而A 1为取代的C _{3-14个烃环基等; R 2和R 3相同或不同，并且各自为氢原子， - （CH 2）2 N 其中p和q为 - （CH 2）2 - - - - CH 2 - 相同或不同，并且各自为0至6，X 1为单键等，而A 2为任选取代的C 3-14烷基，烃环等; R 4是-CO 2 R 9等，其中R 9是氢原子等。 ; 和R 20和R 21相同或不同，各自为氢原子， - （CH 2 CH 2）m 12 其中m12和m12（其中m12和m12）相同或不同，各自为0至6，X 12为单键等，R 30为氢原子等; 或其前药或其药学上可接受的盐。}

35. 发明申请

US20060240270A1 Aluminum alloy sheet, method for producing the same, and aluminum alloy container 有权
标题翻译：铝合金板，其制造方法和铝合金容器
公开(公告)号：US20060240270A1
公开(公告)日：2006-10-26
申请号：US11109637
申请日：2005-04-20
申请人： Kenji Kuroda , Etsuko Kuroda , Takashi Inaba
发明人： Kenji Kuroda , Etsuko Kuroda , Takashi Inaba
IPC分类号： C22F1/04 , B32B15/20
CPC分类号： C22C21/08
摘要： An aluminum alloy sheet contains 0.1% to 0.4% by mass of Cu, 0.5% to 1.5% by mass of Mg, 0.5% to 1.5% by mass of Mn, 0.2% to 0.7% by mass of Fe, and 0.1% to 0.3% by mass of Si. The number density of Al—Mn—Fe—Si-based intermetallic compound having a maximum length of 8 to 15 μm per unit area is 179 grains/mm2 or less. An oxide film having an average thickness of 30 nm or less is formed on the surface of the aluminum alloy sheet. The arithmetic average roughness Ra of the surface of the aluminum alloy sheet is 0.30 to 0.45 μm.
摘要翻译：铝合金板含有0.1质量％〜0.4质量％的Cu，0.5〜1.5质量％的Mg，0.5〜1.5质量％的Mn，0.2〜0.7质量％的Fe，0.1〜0.3 质量％的Si。每单位面积最大长度为8〜15μm的Al-Mn-Fe-Si系金属间化合物的数密度为179粒/ mm 2以下。在铝合金板的表面上形成平均厚度为30nm以下的氧化膜。铝合金板的表面的算术平均粗糙度Ra为0.30〜0.45μm。

36. 发明申请

US20060199826A1 Cyclopropane compounds and pharmaceutical use thereof 失效
标题翻译：环丙烷化合物及其药物用途
公开(公告)号：US20060199826A1
公开(公告)日：2006-09-07
申请号：US11011773
申请日：2004-12-15
申请人： Takashi Inaba , Julia Haas , Makoto Shiozaki , Nicole Littmann , Katsutaka Yasue , Steven Andrews , Atushi Sakai , Andrew Fryer , Takafumi Matsuo , Ellen Laird , Akira Suma , Yuichi Shinozaki , Yoshikazu Hori , Hiroto Imai , Tamotsu Negoro
发明人： Takashi Inaba , Julia Haas , Makoto Shiozaki , Nicole Littmann , Katsutaka Yasue , Steven Andrews , Atushi Sakai , Andrew Fryer , Takafumi Matsuo , Ellen Laird , Akira Suma , Yuichi Shinozaki , Yoshikazu Hori , Hiroto Imai , Tamotsu Negoro
IPC分类号： A61K31/496 , A61K31/4436 , A61K31/416 , C07D49/02
CPC分类号： C07C311/29 , C07C311/13 , C07C311/20 , C07C311/22 , C07C311/46 , C07C2601/02 , C07C2601/14 , C07C2603/08 , C07C2603/18 , C07C2603/30 , C07D205/04 , C07D207/48 , C07D209/44 , C07D211/58 , C07D211/96 , C07D213/18 , C07D213/65 , C07D213/71 , C07D213/74 , C07D213/81 , C07D213/82 , C07D217/08 , C07D231/12 , C07D233/64 , C07D237/12 , C07D239/22 , C07D243/08 , C07D257/04 , C07D261/08 , C07D271/06 , C07D271/107 , C07D277/26 , C07D277/36 , C07D277/82 , C07D295/26 , C07D307/79 , C07D307/91 , C07D333/18 , C07D333/34 , C07D333/36 , C07D333/38 , C07D333/62 , C07D401/04 , C07D409/04 , C07D409/12 , C07D413/04 , C07D417/04 , C07D417/12 , C07D471/04 , C07D487/04 , C07D513/04
摘要： The present invention provides a compound having aggrecanase inhibitory activity and MMP-13 inhibitory activity, and useful as a therapeutic agent for osteoarthritis, rheumatoid arthritis and the like, more specifically, a cyclopropane compound of formula (1): wherein R1 is —(CH2)m—X—(CH2)n-A1 etc., wherein m and n are the same or different and each is 0 to 6, X1 is a single bond, etc. and A1 is a substituted C3-14 hydrocarbon ring group, etc.; R2 and R3 are the same or different and each is a hydrogen atom, —(CH2)p—X1-(CH2)q-A2, etc., wherein p and q are the same or different and each is 0 to 6, X1 is a single bond, etc. and A2 is an optionally substituted C3-14 hydrocarbon ring group, etc.; R4 is —CO2R9, etc., wherein R9 is a hydrogen atom, etc.; and R20 and R21 are the same or different and each is a hydrogen atom, —(CH2)m12—X12—(CH2)m12—R30, etc., wherein m12 and m12 are the same or different and each is 0 to 6, X12 is a single bond, etc. and R30 is a hydrogen atom, etc.; or a prodrug thereof or a pharmaceutically acceptable salt thereof.
摘要翻译：本发明提供具有聚集蛋白聚糖蛋白聚糖酶抑制活性和MMP-13抑制活性的化合物，可用作骨关节炎，类风湿性关节炎等的治疗剂，更具体而言，可以使用式（1）的环丙烷化合物：其中R 1 是 - （CH 2）2 -X-（CH 2）n - SUP> 1等，其中m和n相同或不同，并且各自为0至6，X 1是单键等，而A 1， SUP>是取代的C 3-14烃环基等; R 2和R 3相同或不同，并且各自为氢原子， - （CH 2）2 N 其中p和q为 - （CH 2）2 - - - - CH 2 - 相同或不同，并且各自为0至6，X 1为单键等，而A 2为任选取代的C 3-14烷基，烃环等; R 4是-CO 2 R 9等，其中R 9是氢原子等。 ; 和R 20和R 21相同或不同，各自为氢原子， - （CH 2 CH 2）m 12 其中m12和m12（其中m12和m12）相同或不同，各自为0至6，X 12为单键等，R 30为氢原子等; 或其前药或其药学上可接受的盐。

37. 发明申请

US20050202207A1 Method of manufacturing ceramic honeycomb structure 审中-公开
标题翻译：陶瓷蜂窝结构的制造方法
公开(公告)号：US20050202207A1
公开(公告)日：2005-09-15
申请号：US11067703
申请日：2005-03-01
申请人： Takashi Inaba
发明人： Takashi Inaba
IPC分类号： B01D39/20 , B01D53/86 , B01J35/04 , B28B3/26 , B32B3/12 , B65D1/00
CPC分类号： B28B3/269 , B01J35/04 , Y10T428/131 , Y10T428/24149
摘要： A method of manufacturing a ceramic honeycomb structure, includes: an extruding step of extruding a raw material including a ceramic material, and obtaining a ceramic honeycomb intermediate formed article which has substantially the same shape as that of the ceramic honeycomb structure to obtain and whose outer peripheral wall has a thickness of 1/15 to 1/120 with respect to an outer diameter of ceramic honeycomb intermediate formed article; a firing step of firing the obtained ceramic honeycomb intermediate formed article to obtain a ceramic honeycomb fired article; and a machining step of machining the outer peripheral wall of the obtained ceramic honeycomb fired article, and securing a dimensional precision of a predetermined outer diameter. According to the method of manufacturing a ceramic honeycomb structure, a partition wall inside an outer peripheral wall, or the outer peripheral wall itself does not easily deform at an extruding time, and the inside partition walls and through-holes are not exposed at the time of machining of the outer peripheral wall, and any coating layer does not have to be disposed.
摘要翻译：一种陶瓷蜂窝结构体的制造方法，其特征在于，包括：挤出含有陶瓷材料的原料的挤出工序，得到与陶瓷蜂窝结构体的形状大致相同形状的陶瓷蜂窝中间成型体，周壁相对于陶瓷蜂窝中间成型体的外径具有1/15至1/120的厚度; 烧制所得到的陶瓷蜂窝状中间成形体的烧成工序，得到陶瓷蜂窝烧制品; 以及加工所获得的陶瓷蜂窝烧制品的外周壁并确保预定外径的尺寸精度的加工步骤。根据陶瓷蜂窝结构体的制造方法，外周壁内的分隔壁或外周壁本身在挤出时不容易变形，并且在此时内侧隔壁和通孔不露出外周壁的机械加工，并且不必设置任何涂层。

38. 发明授权

US06475635B1 Sliding material made of copper alloy, method of producing same, and sliding bearing 失效
标题翻译：由铜合金制成的滑动材料，其制造方法和滑动轴承
公开(公告)号：US06475635B1
公开(公告)日：2002-11-05
申请号：US09734572
申请日：2000-12-13
申请人： Kenji Sakai , Naohisa Kawakami , Satoru Kurimoto , Takashi Inaba , Koichi Yamamoto , Takayuki Shibayama
发明人： Kenji Sakai , Naohisa Kawakami , Satoru Kurimoto , Takashi Inaba , Koichi Yamamoto , Takayuki Shibayama
IPC分类号： B32B1520
CPC分类号： F16C33/24 , B22F1/0003 , B22F2998/00 , B22F2998/10 , C22C1/0425 , F16C33/121 , F16C2204/12 , Y10T428/12063 , Y10T428/12097 , Y10T428/12118 , Y10T428/1291 , B22F7/02 , B22F3/10
摘要： A copper alloy sliding material which can bring about superior resistance to fatigue as well as good anti-seizure property without containing any Pb. The copper alloy sliding material is made to have the structure in which both of the hard copper alloy phase and the soft copper alloy phase coexist in a mixture state. On the surface of the sliding material, the soft copper alloy phase comes to have a shape more concave than that of the hard copper alloy phase when receiving a load or when being in a sliding wear relation, in which concave portions is retained lubricant with the result that the anti-seizure property is enhanced. Further, since the soft phase and the hard phase are made of the same copper alloy, the wettability thereof becomes good, and Ni and etc. contained in the hard copper alloy phase are diffused into the soft copper alloy phase, so that the hardness of the boundary portion defined between the phases come to be gradually varied. Thus, because of the unclear boundary, the load received in the hard phase comes to be spread in a wide range without being concentrated at the boundary, so that the fatigue strength is enhanced.
摘要翻译：一种铜合金滑动材料，可以带来优异的抗疲劳性以及良好的抗咬合性能，不含任何Pb。使铜合金滑动材料具有混合状态下硬铜合金相和软铜合金相共存的结构。在滑动材料的表面上，软铜合金相的形状比硬铜合金相的形状比承受载荷或滑动磨损关系时更凹形，其中凹部保持有润滑剂导致抗发作性能得到提高。此外，由于软相和硬相由相同的铜合金制成，所以其润湿性良好，硬铜合金相中所含的Ni等扩散到软铜合金相中，使得硬度两相之间界定的边界部分逐渐变化。因此，由于边界不清楚，硬相中承受的载荷在宽范围内扩散而不会集中在边界处，从而提高了疲劳强度。

39. 发明授权

US06378670B1 Sliding member 失效
标题翻译：滑动构件
公开(公告)号：US06378670B1
公开(公告)日：2002-04-30
申请号：US09457326
申请日：1999-12-09
申请人： Naohisa Kawakami , Tsukimitsu Higuchi , Takashi Inaba , Koichi Yamamoto , Toshio Egami , Takayuki Shibayama
发明人： Naohisa Kawakami , Tsukimitsu Higuchi , Takashi Inaba , Koichi Yamamoto , Toshio Egami , Takayuki Shibayama
IPC分类号： F16D6900
CPC分类号： E04H9/021 , F16D2069/002
摘要： There is disclosed a sliding member which slidably contacts an counterpart member with friction and in which a friction force is varied without changing a contact pressure. A sliding member 11 is formed by covering a steel plate with sliding materials 13a to 13e different in friction coefficient. In this case, when a sliding direction of the counterpart member 14 is set to directions of arrows A and B, a sliding material 13a of a low friction coefficient is disposed in the middle, and the sliding materials 13b to 13e are arranged so that the friction coefficient gradually increases toward both terminal sides in the directions of arrows A and B of the sliding material 13a. According to the sliding member 11, the friction force increases as the counterpart member 14 moves in the directions of arrows A and B from the middle.
摘要翻译：公开了一种滑动构件，其以摩擦力滑动地接触配对构件，并且摩擦力在不改变接触压力的情况下变化。滑动构件11通过用摩擦系数不同的滑动材料13a至13覆盖钢板而形成。在这种情况下，当将配对构件14的滑动方向设定为箭头A和B的方向时，在中间设置低摩擦系数的滑动材料13a，并且滑动材料13b至13e被布置成使得摩擦系数沿着滑动材料13a的箭头A和B的方向朝向两个末端侧逐渐增加。根据滑动构件11，摩擦力随着对方构件14从中间沿箭头A和B的方向移动而增加。

40. 发明授权

US06252085B1 Production of amide derivatives and intermediates therefor 失效
标题翻译：酰胺衍生物及其中间体的生产
公开(公告)号：US06252085B1
公开(公告)日：2001-06-26
申请号：US09580831
申请日：2000-05-30
申请人： Takashi Inaba , Yasuki Yamada
发明人： Takashi Inaba , Yasuki Yamada
IPC分类号： C07D26308
CPC分类号： C07D413/04 , C07C319/14 , C07D217/26 , C07D263/14 , C07D321/06 , C07C323/25 , C07C323/42
摘要： A method for producing an amide derivative of the formula [XV] wherein each-symbol is as defined in the specification, and an enantiomer thereof, a novel intermediate useful for producing said compound and a production method thereof. The production method of the present invention is extremely easy and simple as compared to the conventional methods, and enables effective production of compound [XV] at high yields, which includes compound [XVI] having an HIV protease inhibitory action. In addition, the novel intermediates of the present invention are extremely useful as intermediates for producing not only the aforementioned compound [XVI] but also compounds useful as X-ray contrast media.
摘要翻译：一种制备式[XV]的酰胺衍生物的方法，其中每个符号如说明书中所定义，及其对映异构体，可用于制备所述化合物的新型中间体及其制备方法。本发明的制备方法与常规方法相比非常容易和简单，并且能够以高产率有效生产化合物[XV]，其包括具有HIV蛋白酶抑制作用的化合物[XVI]。此外，本发明的新型中间体作为用于生产上述化合物[XVI]的中间体以及用作X射线造影剂的化合物是非常有用的。

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