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    • 32. 发明授权
    • Switching device with a switching element driven via a flexible shaft
    • 具有通过柔性轴驱动的开关元件的开关装置
    • US08779310B2
    • 2014-07-15
    • US13560677
    • 2012-07-27
    • Klaus KeimMichael MannTobias ErfordDaniel KuhlDavid SaxlPeter Klonecki
    • Klaus KeimMichael MannTobias ErfordDaniel KuhlDavid SaxlPeter Klonecki
    • H01H9/20H01H11/00
    • H01H9/16H01H3/02H01H3/38H01H3/40H01H71/04H01H71/56
    • A switching device includes a switching element movable from a first position into a second position, a drive unit producing a rotary movement, and a flexible shaft transmitting the rotary movement to the switching element. The shaft has rotatable input and output sections on input- and output-drive sides, respectively. During movement of the shaft, a first rotary angle is producible at the output section, which first rotary angle is less than a second rotary angle at the input section at the same time, such that a first rotary angle shift is produced. The input section is connected to a switching position detection element having a control means with a first region which corresponds to the first position of the switching element and is coupled to the detection element. An identical indication of the detection element can be achieved in case of different rotary angle shifts in the same electrical switching state.
    • 开关装置包括可从第一位置移动到第二位置的开关元件,产生旋转运动的驱动单元和将旋转运动传递到开关元件的柔性轴。 轴在输入和输出驱动侧分别具有可旋转的输入和输出部分。 在轴的移动期间,在输出部分可以产生第一旋转角度,该第一旋转角度在输入部分同时第一旋转角度小于第二旋转角度,使得产生第一旋转角度偏移。 输入部分连接到具有控制装置的切换位置检测元件,该控制装置具有对应于开关元件的第一位置的第一区域并耦合到检测元件。 在相同的电开关状态下的不同的旋转角度偏移的情况下,可以实现检测元件的相同指示。
    • 37. 发明申请
    • METHODS OF INCREASING LEAN TISSUE MASS USING OB PROTEIN COMPOSITIONS
    • 使用OB蛋白组合物增加组织质量的方法
    • US20070224193A1
    • 2007-09-27
    • US11687591
    • 2007-03-16
    • Mary PelleymounterChristopher ToombsMichael Mann
    • Mary PelleymounterChristopher ToombsMichael Mann
    • A61K39/395A61K39/00C12N1/21C12N15/63C12P21/02
    • C07K14/5759A61K38/2264C07K2319/30
    • DNA sequences comprising nucleic acids encoding fusion proteins comprising an Fc portion of an antibody attached at the N-terminus of an OB protein moiety, vectors comprising such DNA sequences, host cells comprising such vectors or DNA sequences, and processes for preparing such fusion proteins, and pharmaceutical compositions comprising such fusion proteins, are described. The DNA sequences, vectors comprising such DNA sequences, host cells comprising such vectors or DNA sequences, and processes for preparing such fusion proteins, and pharmaceutical compositions comprising such fusion proteins are useful, for example, in providing therapeutically effective amounts of compositions useful for, for example, increasing insulin sensitivity, decreasing the dose of insulin required for the treatment of diabetes, controlling serum glucose levels, increasing lean tissue mass, increasing overall body strength, or regulating bone resorption, or effecting any combination of such, in subjects in need or desirous thereof to which the compositions are administered.
    • 包含编码融合蛋白的核酸的DNA序列,其包含在OB蛋白部分的N末端连接的抗体的Fc部分,包含该DNA序列的载体,包含该载体或DNA序列的宿主细胞,以及制备该融合蛋白的方法, 和包含这种融合蛋白的药物组合物。 包含这种DNA序列的DNA序列,包含这种载体或DNA序列的宿主细胞,以及制备这种融合蛋白的方法,以及包含这种融合蛋白的药物组合物可用于例如提供治疗有效量的组合物, 例如,增加胰岛素敏感性,减少治疗糖尿病所需的胰岛素剂量,控制血清葡萄糖水平,增加瘦组织质量,增加整体体力或调节骨吸收,或在需要的受试者中进行任何组合 或希望给予组合物。
    • 40. 发明申请
    • Business analysis and management systems utilizing emergent structures
    • 利用紧急结构的业务分析和管理系统
    • US20050177415A1
    • 2005-08-11
    • US10959640
    • 2004-10-07
    • Michael MannArne Haugland
    • Michael MannArne Haugland
    • G06Q10/00G06F17/60G06F7/00
    • G06Q10/06G06Q10/0637
    • The emergent structure analysis of the present invention enhances a computer-supported tool for improved enterprise process analysis and change management. The new and improved system and method of the present invention collects data on the patterns of interaction among people in an organization, analyzes these relationships with respect to specific organizational processes and issues, and presents the results in a graphical format useful for business management organization decisions. The emergent structure analysis is a selection and transformation process. Its data are the issues that have been defined as important for an organizational or system study and the organization members' reported perceptions of their regular interactions with others about those issues, as gathered by a specialized data collection instrument. According to criteria defined by an analyst using appropriate software in accordance with the invention, the process selects a subset of this raw data, creates a suitable structure, and connects each person record to its appropriate level in the structure.
    • 本发明的紧急结构分析增强了用于改进企业过程分析和变更管理的计算机支持的工具。 本发明的新的和改进的系统和方法收集关于组织中的人之间的交互模式的数据,分析关于特定组织过程和问题的这些关系,并且以对于业务管理组织决策有用的图形格式呈现结果 。 紧急结构分析是一个选择和转型过程。 其数据是针对组织或系统研究以及组织成员报告的与其他人就这些问题进行的定期互动的看法,被专门的数据收集工具收集的问题。 根据根据本发明的使用适当软件的分析者定义的标准,该过程选择该原始数据的子集,创建合适的结构,并将每个人记录连接到其结构中的适当水平。