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    • 33. 发明授权
    • Triphendioxazine pigments
    • 三苯并二恶嗪颜料
    • US07524953B2
    • 2009-04-28
    • US10586093
    • 2005-01-12
    • David BlumCarsten PluegTanja Reipen
    • David BlumCarsten PluegTanja Reipen
    • C07D498/02C09B19/02
    • C09B19/02
    • The invention relates to novel triphendioxazine pigments of formula (I) wherein X represents hydrogen or chlorine, while R1 represents phenyl substituted by one to five radicals from the group comprising C1-C4-alkyl, halogen, C1-C4-alkoxy, acetylamino, aminocarbonyl, methylaminocarbonyl and C1-C4-alkoxycarbonyl, or phenyl annelated in the 2,3- or 3,4- with a divalent radical of the formula —NH—(CO)m—NR2—, —CR2═CH—CO—NH—, —CR2═N—CO—NH—, —CO—NH—CO—NR2—, —CO—(NH)m—CO— or —O—(CO)m—NH— so as to form a five- or six-membered ring, R2 representing hydrogen, methyl, ethyl or phenyl and m representing 1 or 2.
    • 本发明涉及式(I)的新型三苯并二恶嗪颜料,其中X表示氢或氯,而R1表示被一至五个基团取代的苯基,该基团包括C 1 -C 4烷基,卤素,C 1 -C 4 - 烷氧基,乙酰氨基,氨基羰基 或甲基氨基羰基和C 1 -C 4烷氧基羰基,或在2,3-或3,4-中与式-NH-(CO)m -NR 2 - ,-CR 2 -CH-CO-NH- ,-CR2-N-CO-NH-,-CO-NH-CO-NR2-,-CO-(NH)m -CO-或-O-(CO)m-NH-,以便形成五 六元环,R 2代表氢,甲基,乙基或苯基,m代表1或2。
    • 35. 发明申请
    • Process for preparation of 4-amino-3-quinolinecarbonitriles
    • 制备4-氨基-3-喹啉碳腈的方法
    • US20080033175A1
    • 2008-02-07
    • US11973259
    • 2007-10-05
    • Karen SutherlandGregg FeigelsonDiane BoschelliDavid BlumHenry Strong
    • Karen SutherlandGregg FeigelsonDiane BoschelliDavid BlumHenry Strong
    • C07D401/00C07D471/02
    • C07D405/04C07D215/54C07D495/04
    • This invention discloses a process for the preparation of a 4-amino-3-quinolinecarbonitrile comprising combining an amine compound with a cyanoacetic acid and an acid catalyst to yield a cyanoacetamide; condensing the cyanoacetamide with an optionally up to tetra-substituted aniline in an alcoholic solvent and a trialkylorthoformate to yield a 3-amino-2-cyanoacrylamide; combining the 3-amino-2-cyanoacrylamide with phosphorus oxychloride in acetonitrile, butyronitrile, toluene or xylene, optionally in the presence of a catalyst to yield a 4-amino-3-quinolinecarbonitrile and also discloses a process for the preparation of a 7-amino-thieno[3,2-b]pyridine-6-carbonitrile comprising combining a disubstituted 3-amino thiophene with a cyanoacetamide and trialkylorthoformate in an alcoholic solvent to obtain a 3-amino-2-cyanoacrylamide; and combining the 3-amino-2-cyanoacrylamide with phosphorus oxychloride and acetonitrile, butyronitrile, toluene or xylene, optionally in the presence of a catalyst to yield a 7-amino-thieno[3,2-b]pyridine-6-carbonitrile and also discloses a process for the preparation of a 4-amino-3-quinolinecarbonitrile by combining an amine compound with a cyanoacetic acid and a peptide coupling reagent to obtain a suspension; filtering the suspension to yield a cyanoacetamide; condensing the cyanoacetamide with an optionally up to tetra-substituted aniline, an alcoholic solvent, and triethylorthoformate to yield a 3-amino-2-cyanoacrylamide; and combining the 3-amino-2-cyanoacrylamide with phosphorus oxychloride to yield a 4-amino-3-quinolinecarbonitrile.
    • 本发明公开了一种制备4-氨基-3-喹啉甲腈的方法,包括将胺化合物与氰基乙酸和酸催化剂混合以产生氰基乙酰胺; 将氰基乙酰胺与任选至多四取代的苯胺在醇溶剂和三烷基原甲酸酯中缩合,得到3-氨基-2-氰基丙烯酰胺; 任选在催化剂存在下,将3-氨基-2-氰基丙烯酰胺与三氯氧化磷在乙腈,丁腈,甲苯或二甲苯中的混合,得到4-氨基-3-喹啉腈,并公开了制备7-氨基-2-氰基丙烯酰胺的方法, 氨基 - 噻吩并[3,2-b]吡啶-6-甲腈,其包括在醇溶剂中组合二取代的3-氨基噻吩与氰基乙酰胺和三烷基酯,得到3-氨基-2-氰基丙烯酰胺; 并将3-氨基-2-氰基丙烯酰胺与磷酰氯和乙腈,丁腈,甲苯或二甲苯组合,任选在催化剂存在下,得到7-氨基 - 噻吩并[3,2-b]吡啶-6-甲腈和 还公开了通过将胺化合物与氰基乙酸和肽偶联剂组合以制备悬浮液来制备4-氨基-3-喹啉腈的方法; 过滤悬浮液,得到氰基乙酰胺; 将氰基乙酰胺与任选的高达四取代的苯胺,醇溶剂和原甲酸三乙酯缩合,得到3-氨基-2-氰基丙烯酰胺; 并将3-氨基-2-氰基丙烯酰胺与磷酰氯组合,得到4-氨基-3-喹啉腈。
    • 39. 发明授权
    • Paper gripping device
    • 纸夹持装置
    • US5570907A
    • 1996-11-05
    • US338849
    • 1994-11-14
    • Aviva DromiDavid BlumAbraham Pick
    • Aviva DromiDavid BlumAbraham Pick
    • B42F9/00B42F13/42
    • B42F9/00
    • A device for clamping together a plurality of loose leafs including first and second clamp members arranged in a jaw-like arrangement; force responsive closure apparatus for closing the first and second clamp members together in response to an externally applied closure force so as cause the first and second clamp members to enclose therebetween a selected plurality of loose leafs and so as to apply a clamping force thereto; and releasable locking apparatus for selectably locking the first and second clamp members together in clamping engagement with the plurality of loose leafs.
    • 一种用于将多个松散叶片夹紧在一起的装置,包括以颚状布置布置的第一和第二夹紧构件; 力响应闭合装置,用于响应于外部施加的闭合力将第一和第二夹紧构件关闭在一起,从而使第一和第二夹紧构件在其间包围所选择的多个松散叶片并且向其施加夹紧力; 以及用于将第一和第二夹紧构件可选择地锁定在一起以与多个松散叶片夹紧接合的可释放锁定装置。