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31. 发明申请

US20110259325A1 Delivery of ultra pure nitric oxide (NO) 有权
标题翻译：超纯氧化氮（NO）
公开(公告)号：US20110259325A1
公开(公告)日：2011-10-27
申请号：US13094535
申请日：2011-04-26
申请人： David H. Fine , Gregory Vasquez , Bryan Johnson , Ryan Denton , Lucas G. Gamero
发明人： David H. Fine , Gregory Vasquez , Bryan Johnson , Ryan Denton , Lucas G. Gamero
IPC分类号： A61M16/10 , B65D8/04 , B65D85/00 , B65B1/04
CPC分类号： A61M16/122 , A61M16/0666 , A61M16/10 , A61M16/105 , A61M16/1055 , A61M16/107 , A61M16/1075 , A61M16/12 , A61M2016/0027 , A61M2016/102 , A61M2202/0266 , A61M2202/0275 , A61M2202/03 , A61M2205/0238 , A61M2205/18 , A61M2205/3368 , A61M2205/3653 , A61M2205/7518 , A61M2205/8206 , A61M2207/10 , A61M2209/088 , C01B21/24
摘要： A system for deliverying a therapeutic amount of nitric oxide can include a reservoir assembly, a gas supply, and a delivery conduit including a first cartridge, wherein the first cartridge can include a surface-activated material saturated with an aqueous solution of a reducing agent.
摘要翻译：用于递送治疗量的一氧化氮的系统可以包括储存器组件，气体供应和包括第一盒的输送导管，其中第一盒可包括饱和还原剂的水溶液的表面活化材料。

32. 发明申请

US20110220103A1 NITRIC OXIDE DELIVERY SYSTEM 有权
标题翻译：氮氧化物输送系统
公开(公告)号：US20110220103A1
公开(公告)日：2011-09-15
申请号：US12951811
申请日：2010-11-22
申请人： David H. Fine , Gregory Vasquez , Bryan Johnson , Jody Fuller , Ryan Denton
发明人： David H. Fine , Gregory Vasquez , Bryan Johnson , Jody Fuller , Ryan Denton
IPC分类号： A61M16/12
CPC分类号： A61M16/104 , A61K33/00 , A61M16/0057 , A61M16/0066 , A61M16/1075 , A61M16/12 , A61M2016/102 , A61M2202/0208 , A61M2202/0275 , A61M2205/8206
摘要： An ambulatory or stationary device for delivery of a therapeutic amount of nitric oxide to an individual's lungs.
摘要翻译：用于将治疗量的一氧化氮递送至个体肺的移动或固定装置。

33. 发明申请

US20050158704A1 Method of analyzing blood 有权
标题翻译：分析血液的方法
公开(公告)号：US20050158704A1
公开(公告)日：2005-07-21
申请号：US10761535
申请日：2004-01-21
申请人： David Tyvoll , Winthrop Childers , Kirk Norton , Bryan Johnson
发明人： David Tyvoll , Winthrop Childers , Kirk Norton , Bryan Johnson
IPC分类号： A61B5/00 , G01N33/487 , G01N33/49 , C12Q1/00
CPC分类号： A61B5/1486 , A61B5/14532 , A61B2562/0295 , G01N27/3271 , G01N33/491 , Y10T436/144444 , Y10T436/25 , Y10T436/25125 , Y10T436/25375
摘要： A method of analyzing blood comprises delivering a blood sample to a test device, applying a spatially varying electric field to the blood sample to provide a depleted cell concentration in a portion of the blood sample, and sensing a property of the portion of the blood sample.
摘要翻译：分析血液的方法包括将血液样品递送到测试装置，向血液样品施加空间变化的电场，以在血液样品的一部分中提供耗尽的细胞浓度，并感测血液样品的一部分的性质。

34. 发明授权

US5483720A Sponge mop 失效
标题翻译：海绵拖把
公开(公告)号：US5483720A
公开(公告)日：1996-01-16
申请号：US267979
申请日：1994-06-29
申请人： Carl Decoopman , Bryan Johnson
发明人： Carl Decoopman , Bryan Johnson
IPC分类号： A47L13/258 , A47L13/146
CPC分类号： A47L13/258
摘要： A sponge mop including a mount connected to a handle, the mount including at least one elongate support element designed to receive a spongy layer. The spongy layer is fixed to the support by a releasable fixing element including at least two fixing slides secured to the support, and at least one hooking slab secured to the spongy layer and designed to co-operate with the fixing slides. The slides are slidably mounted in slideway-forming element. The sponge mop also includes two lateral wings that are pivotally mounted and capable of being moved by a control element between a mopping position and a wringing-out position. A socket device may be provided for connecting the handle to the mount.
摘要翻译：包括连接到手柄的安装件的海绵拖把，所述安装件包括设计成接收海绵层的至少一个细长支撑元件。海绵层通过可释放的固定元件固定到支撑件，该可释放的固定元件包括固定到支撑件上的至少两个固定滑动件，以及固定到海绵层并被设计成与固定滑块配合的至少一个钩板。滑块可滑动地安装在滑道形成元件中。海绵拖把还包括枢转地安装并能够通过控制元件在拖地位置和拧出位置之间移动的两个侧翼。可以提供用于将手柄连接到安装座的插座装置。

35. 发明申请

US20200337285A1 FISHING AID DEVICE 审中-公开
公开(公告)号：US20200337285A1
公开(公告)日：2020-10-29
申请号：US16397654
申请日：2019-04-29
申请人： Bryan Johnson
发明人： Bryan Johnson
IPC分类号： A01K87/00 , A01K87/04
摘要： A fishing aid device that is a miniature size and doesn't need a battery. The fishing aid device includes a housing; a fishing aid member disposed in the housing; and an actuating assembly disposed in the housing for energizing the fishing aid member.

36. 发明申请

US20170233877A9 SYNTHESIS OF HETERO COMPOUNDS USING DIALKYLCARBONATE QUATERNATION 有权
公开(公告)号：US20170233877A9
公开(公告)日：2017-08-17
申请号：US13526432
申请日：2012-06-18
申请人： Cody A. Friesen , Derek Wolfe , Paul Bryan Johnson
发明人： Cody A. Friesen , Derek Wolfe , Paul Bryan Johnson
IPC分类号： H01M8/22
CPC分类号： H01M6/045 , C07D471/04 , C07D471/08 , C07D487/08 , C25B9/06 , H01M2/162 , H01M4/244 , H01M4/38 , H01M10/26 , H01M12/06 , H01M2004/021 , H01M2004/023 , H01M2300/0014 , H01M2300/0045
摘要： Methods of preparing hetero ionic complexes, and ionic liquids from bisulfate salts of heteroatomic compounds using dialkylcarbonates as a primary quaternizing reactant are disclosed. Also disclosed are methods of making electrochemical cells comprising the ionic liquids, and an electrochemical cell comprising an alkaline electrolyte and a hetero ionic complex additive.

37. 发明授权

US08741491B2 Ionic liquid containing sulfonate ions 有权
标题翻译：含离子液体的磺酸根离子
公开(公告)号：US08741491B2
公开(公告)日：2014-06-03
申请号：US13448923
申请日：2012-04-17
申请人： Derek Wolfe , Cody A. Friesen , Paul Bryan Johnson
发明人： Derek Wolfe , Cody A. Friesen , Paul Bryan Johnson
IPC分类号： H01M8/22 , C07D471/04 , C07D487/08 , C07D233/58 , C07C309/08 , C07C309/14
CPC分类号： H01M6/045 , C07D471/04 , C07D471/08 , C07D487/08 , C25B9/06 , H01M2/162 , H01M4/244 , H01M4/38 , H01M10/26 , H01M12/06 , H01M2004/021 , H01M2004/023 , H01M2300/0014 , H01M2300/0045
摘要： Embodiments are related to ionic liquids and more specifically to ionic liquids used in electrochemical metal-air cells in which the ionic liquid includes sulfonate ions as the anion.
摘要翻译：实施例涉及离子液体，更具体地涉及电化学金属 - 空气电池中使用的离子液体，其中离子液体包括磺酸根离子作为阴离子。

38. 发明授权

US08476409B2 Bispecific anti-IGF-1R and anti-ErbB3 antibodies 有权
标题翻译：双特异性抗IGF-1R和抗ErbB3抗体
公开(公告)号：US08476409B2
公开(公告)日：2013-07-02
申请号：US13451135
申请日：2012-04-19
申请人： Jason Baum , Bryan Johnson , Alexey Alexandrovich Lugovskoy , Lihui Xu , Neeraj Kohli , Jonathan Basil Fitzgerald , Sharlene Adams
发明人： Jason Baum , Bryan Johnson , Alexey Alexandrovich Lugovskoy , Lihui Xu , Neeraj Kohli , Jonathan Basil Fitzgerald , Sharlene Adams
IPC分类号： C07K16/30 , C07H21/04 , A61K39/00
CPC分类号： C07K16/2863 , A61K2039/505 , C07K16/2869 , C07K16/30 , C07K16/32 , C07K16/40 , C07K16/468 , C07K2317/31 , C07K2317/33 , C07K2317/35 , C07K2317/52 , C07K2317/565 , C07K2317/60 , C07K2317/622 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要： Provided are bispecific antibodies that are useful as anti-neoplastic agents and that bind specifically to human IGF-1R and human ErbB3. Exemplary antibodies inhibit signal transduction through either or both of IGF-1R and ErbB3.
摘要翻译：提供可用作抗肿瘤剂并且特异性结合人IGF-1R和人ErbB3的双特异性抗体。示例性的抗体通过IGF-1R和ErbB3之一或两者抑制信号转导。

39. 发明申请

US20120285449A1 PRESSURIZED VESSEL OF NITRIC OXIDE (NO) 审中-公开
标题翻译：氮氧化物加压容器（NO）
公开(公告)号：US20120285449A1
公开(公告)日：2012-11-15
申请号：US13492154
申请日：2012-06-08
申请人： David H. Fine , Bryan Johnson
发明人： David H. Fine , Bryan Johnson
IPC分类号： A61M16/12
CPC分类号： A61M16/12 , A61M16/10 , A61M16/122 , A61M2202/0275 , A61M2202/03 , C01B21/24
摘要： A pharmaceutical product can include a pressure vessel containing a pressurized gas including at least about 1% nitric oxide.
摘要翻译：药物产品可包括含有包含至少约1％一氧化氮的加压气体的压力容器。

40. 发明申请

US20120269812A1 MONOSPECIFIC AND BISPECIFIC ANTI-IGF-1R AND ANTI-ERBB3 ANTIBODIES 有权
标题翻译：单一和双重抗IGF-1R和抗ERBB3抗体
公开(公告)号：US20120269812A1
公开(公告)日：2012-10-25
申请号：US13451135
申请日：2012-04-19
申请人： Jason BAUM , Bryan JOHNSON , Alexey Alexandrovich LUGOVSKOY , Lihui XU , Neeraj KOHLI , Jonathan Basil FITZGERALD , Sharlene ADAMS
发明人： Jason BAUM , Bryan JOHNSON , Alexey Alexandrovich LUGOVSKOY , Lihui XU , Neeraj KOHLI , Jonathan Basil FITZGERALD , Sharlene ADAMS
IPC分类号： C07K16/46 , A61P35/00 , C07H21/04 , A61K39/395
CPC分类号： C07K16/2863 , A61K2039/505 , C07K16/2869 , C07K16/30 , C07K16/32 , C07K16/40 , C07K16/468 , C07K2317/31 , C07K2317/33 , C07K2317/35 , C07K2317/52 , C07K2317/565 , C07K2317/60 , C07K2317/622 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要： Provided herein are novel monospecific and bispecific antibodies that are useful as anti-neoplastic agents and that bind specifically to human IGF-1R and human ErbB3. Exemplary antibodies inhibit signal transduction through either or both of IGF-1R and ErbB3. Exemplary polyvalent proteins comprise at least one anti-IGF-1R binding site and at least one anti-ErbB3 binding site. In certain embodiments the binding sites may be linked through an immunoglobulin constant region. Novel antiErbB3 and anti-IGF-1R antibodies (e.g., monoclonal antibodies) are also provided.
摘要翻译：本文提供了可用作抗肿瘤剂并且特异性结合人IGF-1R和人ErbB3的新型单特异性和双特异性抗体。示例性的抗体通过IGF-1R和ErbB3之一或两者抑制信号转导。示例性的多价蛋白质包含至少一个抗IGF-1R结合位点和至少一个抗ErbB3结合位点。在某些实施方案中，结合位点可以通过免疫球蛋白恒定区连接。还提供了新的抗ErbB3和抗IGF-1R抗体（例如，单克隆抗体）。

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