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21. 发明授权

US4036629A 3-(3,4-Epoxy-4-methylcyclohexyl)butyl esters 失效
标题翻译： 3-（3,4-环氧-4-甲基环己基）丁酯
公开(公告)号：US4036629A
公开(公告)日：1977-07-19
申请号：US659079
申请日：1976-02-18
申请人： Jerry G. Strong
发明人： Jerry G. Strong
IPC分类号： A01N43/20 , A01N53/00 , C07D303/16 , A01N9/28
CPC分类号： A01N43/20 , A01N53/00 , C07D303/16
摘要： 3-(3,4-Epoxy-4-methylcyclohexyl)butyl esters form a new class of compounds exhibiting fungicidal activity and plant growth regulant activity. In fungicide tests, the compounds of this invention prove effective against Fusarium oxysporium, Pythium debaryanum, Rhizoctonia solani and Sclerotium rolfsii. In herbicide tests, post-emergent application of the compounds of this invention provides plant growth regulant action, such as cotton defoliation and plant growth retardation activity.
摘要翻译： 3-（3,4-环氧-4-甲基环己基）丁酯形成了一类具有杀真菌活性和植物生长调节活性的化合物。在杀真菌剂试验中，本发明的化合物证明是有效的针对尖孢镰孢，腐败腐霉，茄子丝核菌和罗氏苏格兰菌。在除草剂试验中，本发明化合物的出苗后施用提供植物生长调节作用，例如脱棉和植物生长迟缓活性。

22. 发明授权

US4032543A PG-type 1,11-lactones 失效
标题翻译： PG-TYPE 1,11-LACTONES
公开(公告)号：US4032543A
公开(公告)日：1977-06-28
申请号：US670523
申请日：1976-03-29
申请人： Gordon L. Bundy
发明人： Gordon L. Bundy
IPC分类号： C07C405/00 , C07D309/12 , C07D313/00 , C07D321/00 , A01N9/28
CPC分类号： C07C405/00 , C07D309/12 , C07D313/00 , C07D321/00 , Y10S514/822 , Y10S514/826 , Y10S514/853
摘要： The present invention provides novel lactones of prostaglandin-type free acids and a process for their preparation. These lactones are useful for the same pharmacological purposes as the corresponding prostaglandin-type free acids.
摘要翻译：本发明提供了前列腺素型游离酸的新型1,15内酯及其制备方法。这些内酯可用于与相应的前列腺素型游离酸相同的药理学目的。

23. 发明授权

US4031237A Carbamate insecticides from 5,8-dihydro-5,8-methano-1-naphthol and its derivatives 失效
标题翻译：来自5,8-二氢-5,8-亚甲基-1-萘酚的氨基甲酸酯杀虫剂及其衍生物
公开(公告)号：US4031237A
公开(公告)日：1977-06-21
申请号：US129628
申请日：1971-03-30
申请人： Stanley T. Gough , Michael A. Tobias , Roger P. Napier
发明人： Stanley T. Gough , Michael A. Tobias , Roger P. Napier
IPC分类号： A01N47/22 , A01N47/48 , C07C49/453 , C07C49/643 , C07D303/22 , C07D303/36 , A01N9/28
CPC分类号： C07D303/22 , A01N47/22 , A01N47/48 , C07C49/453 , C07C49/643
摘要： N-substituted carbamates derived from 5,8-dihydro-5,8-methano-1-naphthol and substituted derivatives therefor are new compounds having insecticidal activity. These tricyclic phenols are prepared, for example, by Diels-Alder condensation of cyclopentadiene with 2-cyclohexen-1-one (or substituted derivative), followed by dehydrogenation.
摘要翻译：衍生自5,8-二氢-5,8-亚甲基-1-萘酚及其取代衍生物的N-取代氨基甲酸酯是具有杀虫活性的新化合物。这些三环酚例如由环戊二烯与2-环己烯-1-酮（或取代的衍生物）的狄尔斯 - 阿尔德缩合，然后脱氢制备。

24. 发明授权

US4024236A Anthelmintic compositions and uses employing amidophenylisothioureas 失效
标题翻译：驱虫组合物和使用酰胺二异硫脲的用途
公开(公告)号：US4024236A
公开(公告)日：1977-05-17
申请号：US578742
申请日：1975-05-19
申请人： Arno Widdig , Engelbert Kuhle , Herbert Thomas , Hans Peter Schulz
发明人： Arno Widdig , Engelbert Kuhle , Herbert Thomas , Hans Peter Schulz
IPC分类号： A61K31/17 , C07C335/38 , A01N9/12 , A01N9/20 , A01N9/28
CPC分类号： C07C335/38 , A61K31/17
摘要： Helmintic infestations can be treated with an N-carbalkoxy-N'-(2-amido-5-alkylphenyl)-S-substituted-isothiourea. A typical embodiment is the treatment of Bunostomum trigonocephalum in sheep utilizing N-methoxycarbonyl-N'-(2-butyramido-5-n-butylphenyl)-S-methylisothiourea. Compositions adapted for this use are also described.
摘要翻译：可以用N-烷基氧基-N' - （2-酰氨基-5-烷基苯基）-S-取代的异硫脲处理螺旋形侵袭物。一个典型的实施方案是使用N-甲氧基羰基-N' - （2-丁酰氨基-5-正丁基苯基）-S-甲基异硫脲处理绵羊中的布诺诺木三叶草。还描述了适用于此用途的组合物。

25. 发明授权

US4013445A 1-(Bis-trifluoromethylphenyl)-2-oxo-pyrrolidine-4-carboxylic acid derivatives, their production and their use as plant-growth regulators and herbicides 失效
标题翻译： 1-（双三氟甲基苯基）-2-氧代 - 吡咯烷-4-羧酸衍生物，其生产及其作为植物生长调节剂和除草剂的用途
公开(公告)号：US4013445A
公开(公告)日：1977-03-22
申请号：US625234
申请日：1975-10-23
申请人： Daniel Bellus , Werner Fory
发明人： Daniel Bellus , Werner Fory
IPC分类号： A01N43/36 , A01N43/60 , A01N55/00 , A01N55/10 , A01P13/00 , A01P21/00 , C07D207/26 , C07D207/277 , C07D401/06 , C07D405/12 , C07F7/18 , A01N9/28
CPC分类号： C07D207/277 , C07F7/1896
摘要： The present invention relates to new 1-(bis-trifluoromethylphenyl)-2-oxo-pyrrolidine-4-carboxylic acid derivatives, to processes for their production, to compositions containing these active substances, as well as to the use of these active substances and compositions for the regulation of plant growth and as herbicides.These derivatives correspond to formula I ##STR1## wherein A represents the nitrile or carboxylic acid group or a derivative of the carboxylic acid.
摘要翻译：本发明涉及新的1-（双三氟甲基苯基）-2-氧代 - 吡咯烷-4-羧酸衍生物，其制备方法，含有这些活性物质的组合物，以及这些活性物质的使用和用于调节植物生长和作为除草剂的组合物。

26. 发明授权

US4009265A Methods and formulations for the treatment of obesity 失效
标题翻译：治疗肥胖的方法和制剂
公开(公告)号：US4009265A
公开(公告)日：1977-02-22
申请号：US338257
申请日：1973-03-05
申请人： Alan Norman Howard
发明人： Alan Norman Howard
IPC分类号： A23L1/29 , A23L1/30 , A23L1/305 , A01N9/00 , A01N9/28
CPC分类号： A23L33/18 , A23L33/115 , A23L33/30 , A23L33/40 , A23V2002/00
摘要： It has been discovered that the unfavorable effects observed in weight reduction treatments based on severe dietary restriction (less than 600 Kcals/day) or total fasting (as regards fat, carbohydrates and aminoacids) are avoided by the administration of aminoacids and carbohydrates in critical but much lower amounts than has been believed to be necessary. Nitrogen loss with aminoacid intake between about 15 and 30 g per day is affected by carbohydrate intake. Nitrogen balance is maintained and ketosis and water retention are controlled when the daily intake includes, in addition to necessary minerals and vitamins, at least 15 g of aminoacids in the proportions required by man, and from 15 to 75 g, preferably 30 to 45 g, of carbohydrates, with a total caloric value of from 160 to about 600 Kcals, preferably less than 400 Kcals, very desirably less than 360 Kcals, and optimally in the range of from 180 to 360 Kcals. Formulations are described in which the least amount containing the minimum daily requirement of minerals also contains at least 15 g of aminoacids (as a monomeric aminoacid mixture or as natural protein) and from 15 to 75 g, preferably from 30 to 45 g, of carbohydrates, together with optional other constituents.

27. 发明授权

US4008253A Bicycloalkanes 失效
标题翻译：双环烷烃
公开(公告)号：US4008253A
公开(公告)日：1977-02-15
申请号：US317549
申请日：1972-12-22
申请人： Gerhard Sauer , Helmut Hauser , Gregor Haffer , Jurgen Ruppert , Ulrich Eder , Rudolf Wiechert
发明人： Gerhard Sauer , Helmut Hauser , Gregor Haffer , Jurgen Ruppert , Ulrich Eder , Rudolf Wiechert
IPC分类号： C07C49/417 , C07D317/30 , C07D317/46 , C07D319/06 , C07D319/12 , A01N9/28
CPC分类号： C07C321/00 , C07C317/00 , C07C323/00 , C07D317/30 , C07D317/46 , C07D319/06
摘要： Bicycloalkane derivatives of the formula ##STR1## WHEREIN N IS 1 OR 2, R.sub.1 is lower alkyl, X is free or ketalized carbonyl or a free, esterified, or etherified hydroxymethylene, and Y is --S--R.sub.2, --SO.sub.m --R.sub.2, or ##STR2## wherein m is 1 or 2, R.sub.2 is alkyl, aryl, or aralkyl, R.sub.3 is hydrogen or lower alkyl, R.sub.4 is alkoxycarbonyl, or acyl or phenyl optionally substituted with lower alkoxy or benzyloxy- or acyloxy; and Z is nitrile, nitro, lower alkoxycarbonyl, lower alkanoyl, lower alkylsulfinyl, or lower alkylsulfonyl are useful intermediates in the total synthesis of steroids. The compounds are prepared by reacting a corresponding compound lacking the CH.sub.2 Y substituent with formaldehyde and a mercaptan or a sulfinic acid, followed if desired by oxidation and optional salt condensation.
摘要翻译：式中，R 1为低级烷基，X为游离的或缩酮化的羰基或游离的，酯化的或醚化的羟基亚甲基，Y为-S-R 2，-SO m -R 2或其中m为1或2，R2为烷基，芳基或芳烷基，R3为氢或低级烷基，R4为烷氧基羰基，或酰基或任选被低级烷氧基或苄氧基或酰氧基取代的苯基; Z是腈，硝基，低级烷氧基羰基，低级烷酰基，低级烷基亚磺酰基或低级烷基磺酰基，是类固醇总合成中的有用中间体。通过使相应的缺少CH 2 Y取代基的化合物与甲醛和硫醇或亚磺酸反应来制备化合物，随后如果需要，通过氧化和任选的盐缩合。

28. 发明授权

US4007206A 2,3:4,6-Di-O(substituted)-2-keto-L-gulonic acid, salts and esters 失效
标题翻译： 2,3：4,6-Di-O（取代的）-2-酮-L-古洛糖酸，盐和酯
公开(公告)号：US4007206A
公开(公告)日：1977-02-08
申请号：US559209
申请日：1975-03-17
申请人： William Szkrybalo
发明人： William Szkrybalo
IPC分类号： C07H9/04 , C07D319/06 , A01N9/28
CPC分类号： C07H9/04
摘要： Plant growth regulant compounds represented by the formula: ##STR1## WHEREIN, WHEN N IS 1, R is hydrogen, sodium, potassium, ammonium, substituted ammonium, straight or branched chain alkyl of from 1 to 20 carbon atoms, straight or branched chain alkenyl of from 1 to 20 carbon atoms, straight or branched chain alkynyl of from 1 to 20 carbon atoms or halo-lower alkyl and, when n is 2, R is calcium, magnesium or lower alkylene, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are hydrogen, straight or branched chain alkyl of from 1 to 7 carbon atoms, straight or branched chain alkenyl of from 1 to 7 carbon atoms, straight or branched chain alkynyl of from 1 to 7 carbon atoms, halo-lower alkyl, aryl or R.sub.1 and R.sub.2 together and R.sub.3 and R.sub.4 together are each a saturated ring containing from 3 to 8 carbon atoms, n is an integer from 1 to 2 and X is a number from 0 to 1; enantiomers and racemic mixtures.These compounds are useful as post-emergence and pre-emergence plant growth regulants and herbicides.
摘要翻译：由下式表示的植物生长调节剂化合物：当N = 1时，R是氢，钠，钾，铵，取代的铵，具有1至20个碳原子的直链或支链烷基，直链或支链烯基 1至20个碳原子的直链或支链炔基或卤代低级烷基，当n为2时，R为钙，镁或低级亚烷基，R 1，R 2，R 3和R 4为氢，1至7个碳原子的直链或支链烷基，1至7个碳原子的直链或支链烯基，1至7个碳原子的直链或支链炔基，卤代低级烷基，芳基或R1和R2 R 3和R 4一起为含有3至8个碳原子的饱和环，n为1至2的整数，X为0至1的数; 对映体和外消旋混合物。

29. 发明授权

US3988464A Cyclopropylamines as pharmaceuticals 失效
标题翻译：环丙胺作为药物
公开(公告)号：US3988464A
公开(公告)日：1976-10-26
申请号：US427999
申请日：1973-12-26
申请人： Charles Malen , Monique Desnos , Michel Laubie , Jean-Claude Poignant
发明人： Charles Malen , Monique Desnos , Michel Laubie , Jean-Claude Poignant
IPC分类号： C07D243/04 , A61K31/13 , A61K31/33 , A61K31/415 , A61K31/42 , A61K31/421 , A61K31/425 , A61K31/426 , A61K31/495 , A61K31/496 , A61K31/505 , A61K31/535 , A61K31/5377 , A61K31/54 , A61K31/55 , A61P9/00 , A61P9/12 , A61P25/00 , A61P25/04 , A61P25/18 , A61P25/20 , A61P27/02 , C07C209/08 , C07C209/60 , C07C211/17 , C07C275/18 , C07C335/08 , C07D233/48 , C07D239/14 , C07D247/02 , C07D263/16 , C07D263/28 , C07D265/06 , C07D265/08 , C07D267/06 , C07D277/18 , C07D279/06 , C07D281/02 , A01N9/22 , A01N9/28
CPC分类号： C07C335/08 , C07C275/18 , C07D233/48 , C07D263/28 , C07D265/06 , C07D277/18 , C07C2101/02
摘要： The present invention relates to cyclopropylmethyl amines substituted by a heterocyclic radical.More particularly the heterocyclic radical is a nitrogen containing ring with 5, 6 or 7 links interrupted by another hetero atom selected from the group consisting of oxygen, sulphur and imino--NH--The invention also relates to the acid addition salts thereof with physiologically compatible mineral or organic acids.The invention extends to the processes for making them and the intermediates produced hereto.The invention also includes the pharmaceutical compositions incorporating as active ingredient at least one compound of the invention with an inert carrier.The compounds have therapeutic utility namely on the cardio-vascular diseases and on the neuro-psychological disturbances.
摘要翻译：本发明涉及被杂环基取代的环丙基甲胺。

30. 发明授权

US3987187A Fungicidal dispersions of 2-methyl-5,6-dihydropyran-3-carboxylic acid anilide 失效
标题翻译： 2-甲基-5,6-二氢吡喃-3-羧酸酰胺的杀菌剂分散体
公开(公告)号：US3987187A
公开(公告)日：1976-10-19
申请号：US618572
申请日：1975-10-01
申请人： Konrad Albrecht , Heinz Frensch , Kurt Hartel
发明人： Konrad Albrecht , Heinz Frensch , Kurt Hartel
IPC分类号： A01N9/28
CPC分类号： Y10S514/943
摘要： Dispersions of 2-methyl-5,6-dihydropyran-3-carboxylic acid anilide in paraffinic mineral oils, liquid triglycerides and/or liquid esters of C.sub.1 to C.sub.12 monoalcohols have an improved effect against rust diseases and an extended spectrum of effectiveness against diseases caused by Colletotrichum types. The dispersions can be stabilized against crystal growth by adding aluminum chelates of certain hydroxy quinones, e.g. allzarin.

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