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    • 29. 发明授权
    • Capillary tube hemoglobinometer and oximeter
    • 毛细管血红蛋白计和血氧计
    • US5061632A
    • 1991-10-29
    • US304744
    • 1989-01-31
    • A. P. ShepherdJohn M. Steinke
    • A. P. ShepherdJohn M. Steinke
    • G01N21/31
    • G01N21/314G01N2021/3144G01N2021/3155G01N2021/3181
    • An oximeter that measures both the total hemoglobin concentration in whole, undiluted blood and the percentage of the hemoglobin saturated with oxygen. The oximeter uses red and infrared light-emitting diodes to illuminate a capillary tube filled with a sample of whole, undiluted blood. Light scattered by the blood travels a short distance down the length of the capillary tube and reaches a photodetector, the output of which is amplified, digitized, and fed to a microprocessor. The microprocessor computes the total hemoglobin concentration as a nonlinear monotonic function of the infrared light intensity. Oxyhemoglobin saturation is computed from the ratio of the logarithms of the intensities of red and infrared light. The invention provides a measurement of oxygen saturation without calibration shifts present in other oximeters due to fluctuations in total hemoglobin concentration. In addition, the present invention is accurate over a wide range of oxygen saturation, and the blood samples are not diluted or hemolyzed and can thus be preserved for further analysis.
    • 测量全血,未稀释血液中的总血红蛋白浓度和用氧饱和血红蛋白的百分比的血氧计。 血氧仪使用红色和红外发光二极管来照亮填充有全部未稀释血液的样品的毛细管。 由血液散射的光沿毛细管的长度向下移动一小段距离,并到达光电检测器,其输出被放大,数字化并送入微处理器。 微处理器将总血红蛋白浓度计算为红外光强度的非线性单调函数。 氧化血红蛋白饱和度是根据红色和红外光强度的对数比计算的。 本发明提供氧饱和度的测量,而由于总血红蛋白浓度的波动,在其它血氧计中不存在校准位移。 此外,本发明在宽范围的氧饱和度范围内是准确的,并且血液样本不被稀释或溶血,因此可以被保留以供进一步分析。