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21. 发明授权

US06978788B2 Minimally invasive treatment for breast cancer 有权
标题翻译：微创治疗乳腺癌
公开(公告)号：US06978788B2
公开(公告)日：2005-12-27
申请号：US10306117
申请日：2002-11-27
申请人： V. Suzanne Klimberg , Steven Harms , Soheila Korourian
发明人： V. Suzanne Klimberg , Steven Harms , Soheila Korourian
IPC分类号： A61B10/00 , A61B10/02 , A61B17/00 , A61B18/24 , A61B19/00
CPC分类号： A61B10/0233 , A61B10/0041 , A61B10/0283 , A61B2017/008 , A61B2018/2005 , A61B2090/374
摘要： The present invention provides a minimally invasive, comprehensive same-day diagnosis and treatment method to remove tumor and ablate margins in breast cancer patients, comprising disease diagnosis by MRI and touch preparation cytology, followed by tumor removal and ablation of tumor margins.
摘要翻译：本发明提供了一种微创，全面的同期诊断和治疗方法，用于消除乳腺癌患者的肿瘤和消融边缘，包括通过MRI和触摸准备细胞学检查的疾病诊断，随后肿瘤切除和肿瘤边缘消融。

22. 发明申请

US20040059254A1 Micro-invasive breast biopsy device 审中-公开
标题翻译：微创乳腺活检装置
公开(公告)号：US20040059254A1
公开(公告)日：2004-03-25
申请号：US10667768
申请日：2003-09-22
申请人： Stryker Puerto Rico Limited
发明人： D. Russell Pflueger
IPC分类号： A61B010/00
CPC分类号： A61B10/0266 , A61B10/0096 , A61B17/32002 , A61B2010/0225 , A61B2017/00261 , A61B2017/00685 , A61B2017/00734 , A61B2017/008
摘要： An apparatus for removing tissue and/or other material from a patient, particularly a breast of a patient, is provided. The apparatus generally includes a handpiece and a tissue removal mechanism connected thereto. The tissue removal mechanism includes a cannula having an open distal tip and an outer diameter of less than about 5 mm, or less than about 2 mm. The mechanism further includes a rotatable element having a distal portion with helical threading. The distal portion of the rotatable element extends beyond the open distal tip of the cannula in order to allow tissue to prolapse between turns of the helical threading. The apparatus is designed to draw soft tissue into the cannula upon rotation of the rotatable element and without the need for supplemental sources of aspiration.
摘要翻译：提供了一种用于从患者，特别是患者的乳房移除组织和/或其他材料的装置。该装置通常包括与其连接的手持件和组织移除机构。组织移除机构包括具有开放的远侧末端和小于约5mm或小于约2mm的外径的套管。该机构还包括具有螺旋螺纹的远侧部分的可旋转元件。可旋转元件的远端部分延伸超过套管的开放的远侧末端，以便允许组织在螺旋螺纹的转动之间脱垂。该装置被设计成在可旋转元件旋转时将软组织吸入套管中，而不需要补充吸入源。

23. 发明授权

US06626903B2 Surgical biopsy device 失效
标题翻译：手术活检装置
公开(公告)号：US06626903B2
公开(公告)日：2003-09-30
申请号：US09844729
申请日：2001-04-27
申请人： James F. McGuckin, Jr. , Peter W. J. Hinchliffe , Stephan A. Defonzo
发明人： James F. McGuckin, Jr. , Peter W. J. Hinchliffe , Stephan A. Defonzo
IPC分类号： A61B1818
CPC分类号： A61B10/02 , A61B10/0041 , A61B10/0266 , A61B17/0218 , A61B17/221 , A61B17/320016 , A61B17/32056 , A61B17/320725 , A61B18/14 , A61B18/1482 , A61B90/39 , A61B90/40 , A61B2017/00287 , A61B2017/00796 , A61B2017/008 , A61B2017/2212 , A61B2017/2215 , A61B2017/32004 , A61B2017/320072 , A61B2018/1407 , A61B2018/2238
摘要： A surgical biopsy apparatus for cutting tissue comprising a housing having a longitudinal axis, first and second members movable from a retracted position to an extended position with respect to the housing, a third member slidably positioned and extendable with respect to the first member, a fourth member slidably positioned and extendable with respect to the second member, and an electrocautery cutting wire slidable with respect to the third and fourth members to surround a region of tissue positioned between the third and fourth members to cut the tissue.
摘要翻译：一种用于切割组织的外科活检装置，包括具有纵向轴线的壳体，第一和第二构件可相对于所述壳体从缩回位置移动到延伸位置;第三构件，其相对于所述第一构件可滑动地定位和延伸;第四构件，可相对于第二构件可滑动地定位和延伸的构件，以及可相对于第三和第四构件滑动的电灼切割线，以围绕定位在第三和第四构件之间的组织区域以切割组织。

24. 发明授权

US6119033A Method of monitoring a location of an area of interest within a patient during a medical procedure 失效
标题翻译：在医疗过程期间监视患者内感兴趣区域的位置的方法
公开(公告)号：US6119033A
公开(公告)日：2000-09-12
申请号：US880477
申请日：1997-06-23
申请人： Zachary S. Spigelman , Richard H. Theriault
发明人： Zachary S. Spigelman , Richard H. Theriault
IPC分类号： A61B10/02 , A61B6/12 , A61B17/00 , A61B19/00 , A61B5/00
CPC分类号： A61B90/36 , A61B34/20 , A61B90/17 , A61B2017/00022 , A61B2017/00115 , A61B2017/008 , A61B2034/105 , A61B2034/2072 , A61B2034/256 , A61B2090/363 , A61B90/39
摘要： Methods and apparatus for a medical imaging system are disclosed. The imaging system is particulary suited for surgical procedures performed with respect to a lesion in a breast, although application of the invention is not so limited. An image of a portion of a patient's anatomy can be displayed on a computer. A surgical instrument and a lesion within the patient's anatomy can be displayed, showing the relative positions of each. A portion of the patient's anatomy can be monitored using markers or sensors that report position relative to an external reference point. Movement of a lesion within soft tissue can be calculated and displayed in response to changes in position or shape of the soft tissue. Accordingly, position of a lesion within a breast can be tracked in response to changes in the shape of the breast as the patient is moved or the breast is manipulated during the procedure. The system can show multiple views, can appropriately magnify the view when the instrument is in a critical position and can provide other signals assisting a surgeon in performing a procedure. Sensors and instruments for use in the system are disclosed. The procedure can be recorded for playback.
摘要翻译：公开了用于医学成像系统的方法和装置。成像系统特别适用于相对于乳房中的损伤进行的外科手术，尽管本发明的应用不限于此。患者解剖结构的一部分的图像可以显示在计算机上。可以显示患者解剖结构内的手术器械和病变，显示每个的相对位置。可以使用报告相对于外部参考点的位置的标记或传感器监测患者解剖结构的一部分。可以根据软组织的位置或形状的变化来计算和显示软组织内病变的运动。因此，可以在手术过程中随着患者的移动或乳房被操纵而响应于乳房形状的变化来跟踪乳房内病变的位置。该系统可以显示多个视图，可以在仪器处于临界位置时适当地放大视图，并且可以提供辅助外科医生执行过程的其他信号。公开了用于该系统的传感器和仪器。可以录制播放过程。

25. 发明授权

US06077231A Apparatus and method for localizing and removing tissue 失效
公开(公告)号：US06077231A
公开(公告)日：2000-06-20
申请号：US971539
申请日：1997-11-17
申请人： Keith L. Milliman , Mitchell J. Palmer , Lisa W. Heaton , Joseph M. DeVivo
发明人： Keith L. Milliman , Mitchell J. Palmer , Lisa W. Heaton , Joseph M. DeVivo
IPC分类号： A61B10/00 , A61B10/02 , A61B17/00 , A61B17/32 , A61B17/34 , A61B18/00 , A61B19/00 , A61B5/00
CPC分类号： A61B10/0266 , A61B17/34 , A61B90/17 , A61B90/39 , A61B17/3417 , A61B2017/008 , A61B2017/32004 , A61B2017/320044 , A61B2018/00077 , A61B2090/3908
摘要： A surgical apparatus for securing a needle extending therethrough includes a post having a channel therein mounted to a base. The post is positioned in operative alignment with the needle mounted on the base. A locking member is associated with the post in operative alignment with the needle. The locking member defines an opening therethrough to receive the needle, and the locking member is operable between a needle receiving position wherein the needle may be inserted or removed from the locking member and a needle retaining position wherein the needle is retained in at least one direction of movement. A method for surgically localizing and removing tissue includes the steps of providing a tissue cutting member mounted on a base and defining an opening near a distal end, the tissue cutting member further forming a tissue receiving cavity in communication with the opening, a needle disposed within the cavity and defining a longitudinal passageway therethrough, a post mounted on the base and a locking member mounted on the post and defining having a needle receiving opening in operative alignment with the needle, the locking member being operable between a needle receiving position wherein the needle may be inserted or removed from the locking member and a needle retaining position wherein the needle is retained in at least one direction of movement, locking the needle within the locking member by rotating the locking member into the needle retaining position, positioning the needle within target tissue, severing the tissue to be removed and removing the severed tissue from a patient.

26. 发明授权

US6036657A Apparatus for removing tissue 有权
标题翻译：用于去除组织的装置
公开(公告)号：US6036657A
公开(公告)日：2000-03-14
申请号：US178730
申请日：1998-10-26
申请人： Keith L. Milliman , Lisa W. Heaton
发明人： Keith L. Milliman , Lisa W. Heaton
IPC分类号： A61B10/00 , A61B10/02 , A61B17/00 , A61B17/32 , A61B17/34
CPC分类号： A61B10/0266 , A61B17/34 , A61B17/3417 , A61B2017/008 , A61B2017/32004 , A61B2017/320044
摘要： A surgical apparatus for removing tissue, which includes a housing, an elongated body which extends from the housing and forms an opening at a distal end, the elongated body further forming a tissue receiving cavity in communication with the opening, a cutting member operatively associated with the housing and movable transverse to the elongated body in proximity to the opening, and a tissue retaining member positioned in proximity to the opening and the cutting member, the retaining member being selectively movable from a retracted position to a deployed position, wherein when positioned in the deployed position, the tissue retaining member obstructs at least a portion of the opening at the distal end of the elongated body. A method is also provided for surgically removing tissue including the steps of positioning a tissue removing instrument including an elongated housing having a tissue receiving cavity at a distal end, a first tissue cutting surface longitudinally movable relative to the elongated housing distal end, an obturator having a sharpened distal end portion such that the sharpened end portion is positioned adjacent the tissue to be removed and a second tissue cutting surface transversely movable relative to the elongated housing, removing the obturator from the elongated housing, coring the tissue to be removed, severing the cored tissue from the surrounding tissue with the second cutting surface, and removing the severed tissue from the patient.
摘要翻译：一种用于去除组织的手术装置，其包括壳体，从所述壳体延伸并在远端形成开口的细长主体，所述细长主体进一步形成与所述开口连通的组织容纳腔，切割构件可操作地与所述壳体和靠近所述开口横向于所述细长体移动;以及组织保持构件，其定位在所述开口和所述切割构件附近，所述保持构件可选择性地从缩回位置移动到展开位置，展开位置，组织保持构件阻挡在细长主体的远端处的开口的至少一部分。还提供了一种用于手术去除组织的方法，包括以下步骤：定位包括在远端具有组织接收腔的细长壳体的组织去除器具，相对于细长壳体远端可纵向移动的第一组织切割表面，尖锐的远端部分，使得尖锐的端部部分邻近待移除的组织定位，并且第二组织切割表面相对于细长的壳体可横向移动，从细长的壳体移除填塞物，将待除去的组织取出，从具有第二切割表面的周围组织的芯组织，并且从患者身上移除切断的组织。

27. 发明授权

US11931116B2 Systems and methods for guiding tissue resection 有权
公开(公告)号：US11931116B2
公开(公告)日：2024-03-19
申请号：US17872606
申请日：2022-07-25
申请人： THE TRUSTEES OF DARTMOUTH COLLEGE
发明人： Venkataramanan Krishnaswamy , Richard J. Barth, Jr. , Keith D. Paulsen
IPC分类号： G06K9/00 , A61B34/00 , A61B34/10 , A61B34/20 , A61B90/00 , G06T7/00 , G06T7/33 , A61B17/00 , A61B17/34
CPC分类号： A61B34/20 , A61B34/10 , A61B34/25 , A61B90/361 , G06T7/0012 , G06T7/33 , A61B2017/008 , A61B2017/3405 , A61B2034/105 , A61B2034/107 , A61B2034/2065 , A61B2090/365 , A61B2090/378 , A61B2090/3908 , A61B2090/395 , G06T2207/30068
摘要： A method for guiding resection of local tissue from a patient includes generating at least one image of the patient, automatically determining a plurality of surgical guidance cues indicating three-dimensional spatial properties associated with the local tissue, and generating a visualization of the surgical guidance cues relative to the surface. A system for generating surgical guidance cues for resection of a local tissue from a patient includes a location module for processing at least one image of the patient to determine three-dimensional spatial properties of the local tissue, and a surgical cue generator for generating the surgical guidance cues based upon the three-dimensional spatial properties. A patient-specific locator form for guiding resection of local tissue from a patient includes a locator form surface matching surface of the patient, and a plurality of features indicating a plurality of surgical guidance cues, respectively.

28. 发明申请

US20170181844A1 IMPLANTABLE DEVICES AND TECHNIQUES FOR ONCOPLASTIC SURGERY 审中-公开
公开(公告)号：US20170181844A1
公开(公告)日：2017-06-29
申请号：US15456030
申请日：2017-03-10
申请人： Focal Therapeutics, Inc.
发明人： Gail S. LEBOVIC , David B. WILLIS , George D. HERMANN , Jonathan M. OLSON
IPC分类号： A61F2/12
CPC分类号： A61F2/12 , A61B17/00 , A61B17/0206 , A61B2017/008 , A61B2090/3908 , A61F2210/0004 , A61F2230/0008 , A61F2230/0013 , A61F2230/0076 , A61F2230/0091 , A61F2250/0059 , A61F2250/0097 , A61F2250/0098
摘要： Described herein are devices for placement in surgically created soft tissue spaces, potential spaces, or cavities. The implantable devices generally include a bioabsorbable body having an open framework that facilitates attachment of tissue thereto in a manner that helps avoid post-surgical deformities. Methods for using the implantable devices in oncoplastic surgery are further described.

29. 发明申请

US20170181843A1 IMPLANTABLE DEVICES AND TECHNIQUES FOR ONCOPLASTIC SURGERY 审中-公开
公开(公告)号：US20170181843A1
公开(公告)日：2017-06-29
申请号：US15455994
申请日：2017-03-10
申请人： Focal Therapeutics, Inc.
发明人： Gail S. LEBOVIC , David B. WILLIS , George D. HERMANN , Jonathan M. OLSON
IPC分类号： A61F2/12 , A61B17/00
CPC分类号： A61F2/12 , A61B17/00 , A61B17/0206 , A61B2017/008 , A61B2090/3908 , A61F2210/0004 , A61F2230/0008 , A61F2230/0013 , A61F2230/0076 , A61F2230/0091 , A61F2250/0059 , A61F2250/0097 , A61F2250/0098
摘要： Described herein are devices for placement in surgically created soft tissue spaces, potential spaces, or cavities. The implantable devices generally include a bioabsorbable body having an open framework that facilitates attachment of tissue thereto in a manner that helps avoid post-surgical deformities. Methods for using the implantable devices in oncoplastic surgery are further described.

30. 发明授权

US09615915B2 Implantable devices and techniques for oncoplastic surgery 有权
公开(公告)号：US09615915B2
公开(公告)日：2017-04-11
申请号：US14808852
申请日：2015-07-24
申请人： Focal Therapeutics, Inc.
发明人： Gail S. Lebovic , David B. Willis , George D. Hermann , Jonathan M. Olson
IPC分类号： A61F2/12
CPC分类号： A61F2/12 , A61B17/00 , A61B17/0206 , A61B2017/008 , A61B2090/3908 , A61F2210/0004 , A61F2230/0008 , A61F2230/0013 , A61F2230/0076 , A61F2230/0091 , A61F2250/0059 , A61F2250/0097 , A61F2250/0098
摘要： Described herein are devices for placement in surgically created soft tissue spaces, potential spaces, or cavities. The implantable devices generally include a bioabsorbable body having an open framework that facilitates attachment of tissue thereto in a manner that helps avoid post-surgical deformities. Methods for using the implantable devices in oncoplastic surgery are further described.

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