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    • 30. 发明申请
    • Hybrid valve apparatus and method for fluid handling
    • 用于流体处理的混合阀装置和方法
    • US20050129584A1
    • 2005-06-16
    • US11034389
    • 2005-01-11
    • James JohnsonNeil PichaMitchel Doktycz
    • James JohnsonNeil PichaMitchel Doktycz
    • B01J19/00B67D7/02C12M1/00C40B60/14G01N1/00G01N1/14G01N35/10G01N37/00B32B27/04
    • G01N35/1097B01J19/0046B01J2219/00315B01J2219/00394B01J2219/00412B01J2219/00605B01J2219/00659C40B60/14F16K11/0743F16K99/0001F16K99/0013F16K99/0028F16K2099/0084G01N1/14G01N2035/1041Y10T137/86863Y10T137/87249Y10T436/2575
    • A hybrid valve apparatus for use with an aspiration actuator and a dispensing actuator to transfer fluid from a reservoir to a test site on a substrate surface. The hybrid valve includes a valve assembly movable between an aspiration condition and a dispensing condition, and a manifold device coupled to the valve assembly. The manifold device includes a fluid aspiration conduit having a first aspiration port in fluid communication with the aspiration actuator. On an opposite end of the aspiration conduit is a second aspiration port in selective fluid communication with the valve assembly to selectively aspirate a liquid sample slug from the reservoir into a discrete sample path when the valve assembly is in the aspiration condition. The manifold device further includes a fluid dispensing conduit having a first dispensing port in fluid communication with the dispensing actuator, and a second dispensing port in selective fluid communication with the valve assembly. When the valve assembly is in the dispensing condition, the sample path is fluidly coupled to the dispensing actuator to selectively dispense at least one droplet of the liquid sample slug therefrom, while simultaneously being out of fluid communication with the aspiration actuator. In contrast, in the aspiration condition, the sample path is in fluid communication with the aspiration actuator, while being out of fluid communication with the dispensing actuator.
    • 一种用于吸入致动器和分配致动器的混合阀装置,用于将流体从储存器传送到衬底表面上的测试位置。 所述混合阀包括可在抽吸条件和分配状态之间移动的阀组件以及联接到所述阀组件的歧管装置。 歧管装置包括具有与抽吸致动器流体连通的第一抽吸端口的流体抽吸导管。 在抽吸导管的另一端是与阀组件选择性流体连通的第二抽吸端口,以便当阀组件处于抽吸状态时,将液体样品块从储存器中选择性地吸入离散的样品路径。 歧管装置还包括具有与分配致动器流体连通的第一分配端口和与阀组件选择性流体连通的第二分配端口的流体分配管道。 当阀组件处于分配状态时,样品路径流体地联接到分配致动器,以选择性地从其中分配液体样品块的至少一个液滴,同时与抽吸致动器脱离流体连通。 相反,在抽吸条件下,样品路径与抽吸致动器流体连通,同时不与分配致动器流体连通。