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21. 发明授权

US07645594B2 Method of preparing assay sample for discriminating bacteria by flow cytometer 有权
标题翻译：用流式细胞仪分析细菌的方法
公开(公告)号：US07645594B2
公开(公告)日：2010-01-12
申请号：US10803667
申请日：2004-03-18
申请人： Yasuhiro Sakai , Yasuyuki Kawashima , Junya Inoue , Yoshiro Ikeuchi
发明人： Yasuhiro Sakai , Yasuyuki Kawashima , Junya Inoue , Yoshiro Ikeuchi
IPC分类号： C12Q1/04 , G01N1/30
CPC分类号： G01N1/30 , C12Q1/04 , G01N2001/302 , Y10T436/108331
摘要： A method of staining bacteria comprises: working a polymethine dye on a sample in the presence of a substance capable of reducing nitrite ions to stain bacteria in the sample. A method of detecting bacteria comprises the following steps of: (1) working a polymethine dye on a sample by a method as described above to stain bacteria in the sample, (2) introducing the thus treated sample into a detecting part of a flow cytometer and irradiating cells of the stained bacteria one by one with light to measure scattered light and fluorescent light emitted from each of the cells; and (3) discriminating the bacteria from other components in accordance with an intensity of a scattered light signal and an intensity of a fluorescent light signal or a pulse width reflecting the length of particles to count the bacteria.
摘要翻译：染色细菌的方法包括：在能够还原亚硝酸根离子的物质存在下在样品上加工聚甲炔染料以染色样品中的细菌。检测细菌的方法包括以下步骤：（1）通过上述方法在样品上加工聚甲炔染料以染色样品中的细菌，（2）将如此处理的样品引入流式细胞仪的检测部分用光照射染色细菌的细胞，测量从每个细胞发出的散射光和荧光; 和（3）根据散射光信号的强度和荧光信号的强度或反映粒子长度的脉冲宽度来区别细菌与其它成分，以计数细菌。

22. 发明授权

US07422870B2 Bacteria counting method 有权
标题翻译：细菌计数法
公开(公告)号：US07422870B2
公开(公告)日：2008-09-09
申请号：US10679146
申请日：2003-10-03
申请人： Yasuyuki Kawashima , Yoshiro Ikeuchi , Yasuhiro Sakai
发明人： Yasuyuki Kawashima , Yoshiro Ikeuchi , Yasuhiro Sakai
IPC分类号： C12Q1/04
CPC分类号： G01N1/30 , C12Q1/06 , G01N15/14
摘要： Methods for counting bacteria are described that include: (a) preparing an assay sample by staining a specimen using a fluorescent dye, thereby producing a difference in fluorescent intensity between live bacteria and dead bacteria; (b) detecting optical information from the assay sample; and (c) classifying and counting the live bacteria and the dead bacteria based on the detected optical information. Bacteria counting apparatuses and reagent kits for counting bacteria are also described.
摘要翻译：描述了计数细菌的方法，包括：（a）通过使用荧光染料染色样品来制备测定样品，从而产生活细菌和死菌之间的荧光强度差异; （b）检测来自测定样品的光学信息; 和（c）根据检测到的光学信息对活细菌和死菌进行分类和计数。还描述了细菌计数装置和用于计数细菌的试剂盒。

23. 发明授权

US07259155B2 Phosphonic diester derivatives 失效
标题翻译：膦酸二酯衍生物
公开(公告)号：US07259155B2
公开(公告)日：2007-08-21
申请号：US10838297
申请日：2004-05-05
申请人： Yasuhiro Sakai , Kazuyoshi Miyata , Takahiro Tomoyasu , Akiyoshi Kuroda , Yasuhide Inoue , Akifumi Hagi , Shinya Miki , Norihiro Yoshinaga , Masako Doi , Yoshihiko Tsuda , Seiichirou Kanou
发明人： Yasuhiro Sakai , Kazuyoshi Miyata , Takahiro Tomoyasu , Akiyoshi Kuroda , Yasuhide Inoue , Akifumi Hagi , Shinya Miki , Norihiro Yoshinaga , Masako Doi , Yoshihiko Tsuda , Seiichirou Kanou
IPC分类号： A61K31/517 , A61K31/675 , A01N43/54 , C07D239/72 , C07D265/32 , C07D413/00 , C07F9/02 , C07D401/00 , C07D403/02 , C07F9/28 , C07F9/547
CPC分类号： C07F9/65586 , C07F9/65068 , C07F9/65583
摘要： The present invention provides a phosphonic acid diester compound represented by General Formula wherein R1, R2, R3 and R4 are the same or different, and represent hydrogen, halogen, lower alkyl or lower alkoxy; R5 is phenyl having on the phenyl ring 1–3 substituents selected from the group consisting of lower alkyl, halogen-substituted lower alkyl, lower alkoxy, halogen-substituted lower alkoxy, phenoxy, benzyloxy, hydroxyl, halogen, nitro, lower alkylthio, di(lower alkyl)amino, lower alkanolyamino, pyrrolidinyl and phenyl, or the like, provided that R5 is not mono(lower alkoxy)pheny; and R6 is lower alkyl; and an ACAT-1 inhibitor containing the compound as an active ingredient.
摘要翻译：本发明提供由通式其中R 1，R 2，R 3和R 4代表的膦酸二酯化合物， / SUB>相同或不同，代表氢，卤素，低级烷基或低级烷氧基; R 5是在苯环上具有1-3个选自低级烷基，卤素取代的低级烷基，低级烷氧基，卤素取代的低级烷氧基，苯氧基，苄氧基，羟基，卤素，硝基，低级烷硫基，二（低级烷基）氨基，低级链烷氨基，吡咯烷基和苯基等，条件是R 5不是单（低级烷氧基）苯基; 和R 6是低级烷基; 和含有该化合物作为活性成分的ACAT-1抑制剂。

24. 发明授权

US07049959B2 Powerless type security device 失效
标题翻译：无电源型安全装置
公开(公告)号：US07049959B2
公开(公告)日：2006-05-23
申请号：US10501912
申请日：2004-02-24
申请人： Yasuhiro Sakai
发明人： Yasuhiro Sakai
IPC分类号： G08B13/08
CPC分类号： H02N2/183 , E05B45/06 , E05B2047/0062 , E05B2047/0068 , E05C3/046 , F03G5/06 , F03G7/08 , G08B13/1654
摘要： The present invention provides a non-power source type monitor device installed in a place where a non-power source system needs to be used or a place preferably suitable for the non-power source system, in which a quantity generated energy not lower than several ten times as much as an output of electric current obtained by usual piezoelectric power generating device using steel balls can be assuredly obtained by striking a piezoelectric ceramics element once. A piezoelectric power generating device is formed commonly with capable of automatically repeatedly striking the piezoelectric ceramics element so that a quantity of generated energy of a practical level can be assuredly ensured as a power source of such type monitor device.
摘要翻译：本发明提供一种非电源型监视装置，其安装在需要使用非电源系统的地方或优选地适合于非电源系统的场合，其中产生的能量不低于数个可以通过将压电陶瓷元件击打一次来确定地获得通过使用钢球的普通压电发电装置获得的电流输出的十倍。压电发电装置通常形成能够自动重复地敲击压电陶瓷元件，从而可以确保确保确保确保确保数量的生成的能量作为这种类型的监视装置的电源。

25. 发明授权

US06972903B2 Visual aid 失效
标题翻译：视觉辅助
公开(公告)号：US06972903B2
公开(公告)日：2005-12-06
申请号：US10474415
申请日：2002-04-12
申请人： Hideo Hara , Kazunaga Shimizu , Fumiaki Koizumi , Yasuhiro Sakai
发明人： Hideo Hara , Kazunaga Shimizu , Fumiaki Koizumi , Yasuhiro Sakai
IPC分类号： G02C9/00 , G02B25/00 , G02B27/00 , G02B27/01 , G02B27/02 , H04N5/64 , G02C1/00
CPC分类号： G02B27/0172 , G02B2027/0129 , G02B2027/0178
摘要： A vision assisting apparatus includes a casing for forming an inversely U-shaped optical path, a light entry, provided at one end of the optical path, through which light enters, a light exit, provided at another end of the optical path, through which light exits in an opposite direction to the light entry, an optical system for processing an image entered via the light entry by using the optical pass and outputting a processed image via the light exit, and attaching structure for attaching the casing to a wearer so that the light exit is positioned close to an eye of the wearer. By forming the inversely U-shaped optical path with the casing, it is possible to provide a sufficiently long optical path in a compact form. Accordingly it is possible to provide the vision assisting apparatus that does not hide facial expressions, is easy to use, and can provide a sufficient length for setting a magnifying optical system without extending the distance in the horizontal direction between the light entry and the light exit.
摘要翻译：视觉辅助装置包括用于形成反U型光路的壳体，设置在光路入射的光路的一端的光入口，设置在光路的另一端的光出射口，通过该光入口光以与光入口相反的方向射出，用于通过使用光学通过处理通过光入口输入的图像的光学系统，并且经由光出口输出经处理的图像，以及用于将外壳附接到佩戴者的附接结构，使得光出口靠近佩戴者的眼睛定位。通过与壳体形成相反的U形光路，可以以紧凑的形式提供足够长的光路。因此，可以提供不隐藏面部表情的视觉辅助装置，易于使用，并且可以提供足够的长度来设置放大光学系统，而不会延伸光入射和光出口之间的水平方向上的距离。

26. 发明授权

US06763869B2 Device for producing thermoplastic resin continuous length sections reinforced with long fibers 有权
标题翻译：用长纤维增强热塑性树脂连续长度段的装置
公开(公告)号：US06763869B2
公开(公告)日：2004-07-20
申请号：US09799582
申请日：2001-03-07
申请人： Yasuhiro Sakai , Rikio Yonaiyama
发明人： Yasuhiro Sakai , Rikio Yonaiyama
IPC分类号： B29C7052
CPC分类号： B29C70/523 , B29B15/125
摘要： In a pultrusion device for producing continuous length sections prepared from thermoplastic resins reinforced with long fibers, the vertical angle (&agr;) of an upstream conical surface of a conical portion, which constitutes a shaping nozzle perforated through the downstream end wall of the device ranges from 15 to 35 degrees and the shaping nozzle has a land portion having a length of 1 to 5 mm in the downstream area subsequent to the upstream conical surface. According to this pultrusion device for producing continuous length sections prepared from thermoplastic resins reinforced with long fibers, the long fibers never undergo any breakage nor fluffing during the opening treatment and this accordingly leads to the substantial reduction of pill-formation. As a result, the opening-impregnation device of the present invention provided at least with the downstream end wall carrying the shaping nozzle (including the land portion) can stably and continuously be operated over a long period of time, without any trouble such as those encountered in the conventional devices.
摘要翻译：在用于生产由长纤维增强的热塑性树脂制备的连续长度段的拉挤成型装置中，构成通过装置的下游端壁穿孔的成形喷嘴的锥形部分的上游锥形表面的垂直角（α）从 15至35度，并且成形喷嘴在上游锥形表面之后的下游区域中具有长度为1至5mm的岸台部分。根据用于生产由长纤维增强的热塑性树脂制备的连续长度部分的该拉挤成型装置，长纤维在开放处理期间不会发生任何断裂或起毛，因此导致药丸形成的显着减少。结果，本发明的开口浸渍装置至少具有承载成形喷嘴（包括焊盘部分）的下游端壁能够长时间稳定且连续地操作，没有任何麻烦，例如那些遇到了传统的设备。

27. 发明授权

US06468992B1 Phosphonic acid diester derivatives 失效
标题翻译：膦酸二酯衍生物
公开(公告)号：US06468992B1
公开(公告)日：2002-10-22
申请号：US09674145
申请日：2000-12-13
申请人： Yasuhiro Sakai , Kazuyoshi Miyata , Kenichi Kawamura , Yoshihiko Tsuda , Yasuhide Inoue
发明人： Yasuhiro Sakai , Kazuyoshi Miyata , Kenichi Kawamura , Yoshihiko Tsuda , Yasuhide Inoue
IPC分类号： C07F940
CPC分类号： C07F9/4065 , C07F9/4006 , C07F9/58 , C07F9/650952
摘要： The present invention provides novel phosphonic acid diester derivatives useful as medicines. The phosphonic acid diester derivatives are represented by the general formula: wherein R1 represents amino group, N-lower alkylamino group, N-lower alkenylamino group, or the like; R2 and R3 represent hydrogen atom, lower alkyl group, halogen atom, lower alkoxy group, or the like; R4 represents hydrogen atom, lower alkyl group or phenyl(lower)alkyl group; R5 and R6 represent lower alkyl group; X, Y and Z represent that all of them are carbon atoms or one of them is nitrogen atom and the other two are carbon atoms; Q represents a single bond or alkylene group; or the pharmacologically acceptable salts thereof.
摘要翻译：本发明提供了可用作药物的新型膦酸二酯衍生物。膦酸二酯衍生物由以下通式表示：其中R1表示氨基，N-低级烷基氨基，N-低级链烯基氨基等; R2和R3表示氢原子，低级烷基，卤素原子，低级烷氧基等; R4表示氢原子，低级烷基或苯基（低级）烷基; R5和R6表示低级烷基; X，Y和Z表示全部为碳原子或其中一个为氮原子，另外两个是碳原子; Q表示单键或亚烷基;或其药理学上可接受的盐。

28. 发明申请

US20140091645A1 LINEAR ACTUATOR 有权
标题翻译：线性执行器
公开(公告)号：US20140091645A1
公开(公告)日：2014-04-03
申请号：US14122085
申请日：2012-04-02
申请人： Hiroshi Nakagawa , Takayoshi Fujii , Takashi Fukunaga , Yasuhiro Sakai , Takashi Onoue
发明人： Hiroshi Nakagawa , Takayoshi Fujii , Takashi Fukunaga , Yasuhiro Sakai , Takashi Onoue
IPC分类号： H02K41/035
CPC分类号： H02K33/18 , H02K33/16 , H02K41/035
摘要： A linear actuator includes an inner core, and an outer core that is provided outside the inner core in a radial direction while being supported by a pair of flat springs. Permanent magnets are formed at one of the inner core and the outer core, and magnetic pole portions are formed at the other of the inner core and the outer core to face the permanent magnet with predetermined gaps formed therebetween. Spacers are respectively provided between the inner core and the flat springs, abutting portions are respectively configured by abutting facing surfaces of the spacers and the inner core and facing surfaces of the spacers and the flat springs adjacent to the spacers in the axial direction, and a plurality of engagement portions including recesses and protrusions are arranged at the abutting portions.
摘要翻译：线性致动器包括内芯和外芯，其在径向方向上设置在内芯的外侧，同时被一对平板弹簧支撑。在内芯和外芯之一处形成永磁体，并且在内芯和外芯之间的另一个上形成磁极部，以与它们之间形成有预定间隙的方式面对永磁体。间隔件分别设置在内芯和板簧之间，邻接部分分别由间隔件的邻接表面和间隔件的内芯和相对表面以及沿轴向方向与间隔件相邻的平面弹簧构成，并且在邻接部分处布置有包括凹部和突起的多个接合部。

29. 发明授权

US08558363B2 Lead frame substrate and method of manufacturing the same, and semiconductor device 失效
标题翻译：引线框架基板及其制造方法以及半导体器件
公开(公告)号：US08558363B2
公开(公告)日：2013-10-15
申请号：US13064205
申请日：2011-03-10
申请人： Takehito Tsukamoto , Susumu Maniwa , Junko Toda , Yasuhiro Sakai
发明人： Takehito Tsukamoto , Susumu Maniwa , Junko Toda , Yasuhiro Sakai
IPC分类号： H01L23/495
CPC分类号： H01L21/4832 , H01L23/3107 , H01L23/49541 , H01L24/32 , H01L24/45 , H01L24/48 , H01L2224/32057 , H01L2224/32245 , H01L2224/45015 , H01L2224/45144 , H01L2224/48091 , H01L2224/48247 , H01L2224/73265 , H01L2224/83385 , H01L2924/00014 , H01L2924/01005 , H01L2924/01006 , H01L2924/01019 , H01L2924/01029 , H01L2924/01033 , H01L2924/01046 , H01L2924/01047 , H01L2924/0105 , H01L2924/01078 , H01L2924/01079 , H01L2924/01082 , H01L2924/014 , H01L2924/15183 , H01L2924/181 , H01L2924/351 , H01L2924/00 , H01L2924/20753 , H01L2924/00015 , H01L2224/05599 , H01L2924/00012
摘要： A lead frame substrate, includes: a metal plate having first and second surfaces; a semiconductor element mounting section, semiconductor element electrode connection terminals, and a first outer frame section formed on the first surface; external connection terminals formed on the second surface and electrically connected with the semiconductor element electrode connection terminals; a second outer frame section formed on the second surface; and a resin layer formed on a gap between the first outer frame and the second outer frame. Each external connection terminal buried in the resin layer has at least one projection formed on a side surface thereof throughout a side lower portion of the first surface.
摘要翻译：引线框架基板，包括：具有第一和第二表面的金属板; 半导体元件安装部，半导体元件电极连接端子和形成在第一面上的第一外框部; 外部连接端子，形成在第二表面上并与半导体元件电极连接端子电连接; 形成在所述第二表面上的第二外框架部分; 以及形成在第一外框和第二外框之间的间隙上的树脂层。埋在树脂层中的每个外部连接端子在其第一表面的整个侧下部具有形成在其侧表面上的至少一个突起。

30. 发明申请

US20110163435A1 Lead frame substrate and method of manufacturing the same, and semiconductor device 失效
标题翻译：引线框架基板及其制造方法以及半导体器件
公开(公告)号：US20110163435A1
公开(公告)日：2011-07-07
申请号：US13064205
申请日：2011-03-10
申请人： Takehito Tsukamoto , Susumu Maniwa , Junko Toda , Yasuhiro Sakai
发明人： Takehito Tsukamoto , Susumu Maniwa , Junko Toda , Yasuhiro Sakai
IPC分类号： H01L23/495 , H01L21/48
CPC分类号： H01L21/4832 , H01L23/3107 , H01L23/49541 , H01L24/32 , H01L24/45 , H01L24/48 , H01L2224/32057 , H01L2224/32245 , H01L2224/45015 , H01L2224/45144 , H01L2224/48091 , H01L2224/48247 , H01L2224/73265 , H01L2224/83385 , H01L2924/00014 , H01L2924/01005 , H01L2924/01006 , H01L2924/01019 , H01L2924/01029 , H01L2924/01033 , H01L2924/01046 , H01L2924/01047 , H01L2924/0105 , H01L2924/01078 , H01L2924/01079 , H01L2924/01082 , H01L2924/014 , H01L2924/15183 , H01L2924/181 , H01L2924/351 , H01L2924/00 , H01L2924/20753 , H01L2924/00015 , H01L2224/05599 , H01L2924/00012
摘要： A lead frame substrate, includes: a metal plate having first and second surfaces; a semiconductor element mounting section, semiconductor element electrode connection terminals, and a first outer frame section formed on the first surface; external connection terminals formed on the second surface and electrically connected with the semiconductor element electrode connection terminals; a second outer frame section formed on the second surface; and a resin layer formed on a gap between the first outer frame and the second outer frame. Each external connection terminal buried in the resin layer has at least one projection formed on a side surface thereof throughout a side lower portion of the first surface.
摘要翻译：引线框架基板，包括：具有第一和第二表面的金属板; 半导体元件安装部，半导体元件电极连接端子和形成在第一面上的第一外框部; 外部连接端子，形成在第二表面上并与半导体元件电极连接端子电连接; 形成在所述第二表面上的第二外框架部分; 以及形成在第一外框和第二外框之间的间隙上的树脂层。埋在树脂层中的每个外部连接端子在其第一表面的整个侧下部具有形成在其侧表面上的至少一个突起。

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