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21. 发明授权

US08920835B2 Paliperidone double-layered osmotic pump controlled release tablet and preparation method thereof 有权
标题翻译：哌啶酮双层渗透泵控释片及其制备方法
公开(公告)号：US08920835B2
公开(公告)日：2014-12-30
申请号：US13512402
申请日：2010-11-22
申请人： Yong Gan , Chunliu Zhu , Qingmin Yang , Jingyi Wang , Xiaoqing Zheng , Li Gan , Xinxin Zhang
发明人： Yong Gan , Chunliu Zhu , Qingmin Yang , Jingyi Wang , Xiaoqing Zheng , Li Gan , Xinxin Zhang
IPC分类号： A61K9/24 , A61K9/28 , A61K31/519 , A61P25/18 , B05D5/00 , A61K9/00 , A61K9/20 , A61K31/517
CPC分类号： A61K9/0004 , A61K9/2086 , A61K9/2866 , A61K31/517
摘要： A paliperidone double-layered osmotic pump controlled release tablet and the preparation method thereof are disclosed. The double-layered osmotic pump controlled release tablet comprises a rigid membrane, a push layer, a drug layer, an isolation layer and an aesthetic coating, wherein the rigid membrane contains a semi-permeable polymer, a porogen and/or a plasticizer and has one or more drug release orifices on one end, the push layer comprises an expanding material, an osmotic agent, a binder, a colorant and a lubricant, the drug layer contains a pharmaceutically active ingredient, a hydrophilic polymer, an osmotic agent, a colorant, a lubricant and an antistatic agent, the isolation layer is located between the inner surface of the rigid membrane and the push layer, and contains a hydrophilic polymer. The paliperidone double-layered osmotic pump controlled release tablet shows an increasing drug release rate at early stage and keeps a constant drug release rate at later stage.
摘要翻译：披露了一种帕培酮双层渗透泵控释片及其制备方法。双层渗透泵控制释放片剂包括刚性膜，推层，药物层，隔离层和美容涂层，其中刚性膜含有半透性聚合物，致孔剂和/或增塑剂，并且具有一个或多个药物释放孔在一端，推层包括膨胀材料，渗透剂，粘合剂，着色剂和润滑剂，药物层含有药物活性成分，亲水性聚合物，渗透剂，着色剂，润滑剂和抗静电剂，隔离层位于刚性膜的内表面和推层之间，并含有亲水性聚合物。帕潘立酮双层渗透泵控释片剂在早期阶段呈现出药物释放速率的增加，药物释放速率在后期保持不变。

22. 发明申请

US20130270775A1 SHAFT SEALING SYSTEM FOR STEAM TURBINES 审中-公开
标题翻译：蒸汽涡轮轴封密封系统
公开(公告)号：US20130270775A1
公开(公告)日：2013-10-17
申请号：US13446696
申请日：2012-04-13
申请人： Daniel Robert Coffey , Guoqiang Lu , John Richard Powers , Steven Paul Scarlata , Christopher David Suttles , Xiaoqing Zheng
发明人： Daniel Robert Coffey , Guoqiang Lu , John Richard Powers , Steven Paul Scarlata , Christopher David Suttles , Xiaoqing Zheng
IPC分类号： F16J15/40
CPC分类号： F01D11/003 , F01D11/04 , F02C7/28 , F05D2220/31 , F05D2240/63 , F05D2260/6022
摘要： A shaft sealing system and method are disclosed for a low pressure turbine section having a rotating member including a shaft and a stationary member surrounding the rotating member and defining a steam flow path. The shaft sealing system comprises at least one seal disposed about each of a first end and a second end of the shaft; and a connection line for conducting steam from the first turbine section to a downstream portion of the turbine. The downstream portion of the turbine has a lower pressure than both of the first turbine section and ambient pressure conditions.
摘要翻译：公开了一种用于低压涡轮机部分的轴密封系统和方法，所述低压涡轮部分具有旋转部件，所述旋转部件包括轴和围绕所述旋转部件并限定蒸汽流动路径的静止部件。所述轴密封系统包括围绕所述轴的第一端和第二端中的每一个设置的至少一个密封件; 以及用于将蒸汽从第一涡轮部分传导到涡轮机的下游部分的连接管线。涡轮机的下游部分的压力低于第一涡轮部分和环境压力条件。

23. 发明授权

US08328198B2 Brush seal 有权
标题翻译：刷子密封
公开(公告)号：US08328198B2
公开(公告)日：2012-12-11
申请号：US12898952
申请日：2010-10-06
申请人： William Edward Adis , Xiaoqing Zheng , Bernard Arthur Couture , Michael Dennis Mack
发明人： William Edward Adis , Xiaoqing Zheng , Bernard Arthur Couture , Michael Dennis Mack
IPC分类号： F16J15/44
CPC分类号： F16J15/16 , F01D11/003 , F05D2240/56 , F16J15/3288
摘要： A brush seal and brush seal segment for use in a rotary device are provided. In one embodiment, the invention provides a brush seal comprising: a plurality of brush seal segments, each segment including: an arcuate fence; an arcuate backplate substantially circumferentially coextensive with the arcuate fence, the arcuate backplate including a first end and a second end; and a plurality of brush seal bristles between the arcuate backplate and the arcuate fence, the plurality of brush seal bristles being angled with respect to a radial axis of the arcuate backplate and at least one of the first end and the second end of the arcuate backplate; and a static member to which at least one of the plurality of brush seal segments is affixed.
摘要翻译：提供用于旋转装置的刷密封和刷密封段。在一个实施例中，本发明提供了一种刷子密封件，其包括：多个刷子密封段，每个段包括：弓形围栏; 基本上与弓形围栏共同延伸的弓形背板，该弧形背板包括第一端和第二端; 以及在所述弓形背板和所述弧形挡板之间的多个刷密封刷毛，所述多个刷密封刷毛相对于所述弧形背板的径向轴线成角度，并且所述弓形背板的第一端和第二端中的至少一个 ; 以及固定所述多个刷子密封段中的至少一个的静止部件。

24. 发明申请

US20110285090A1 SEAL ASSEMBLY INCLUDING PLATEAU AND CONCAVE PORTION IN MATING SURFACE FOR SEAL TOOTH IN TURBINE 有权
标题翻译：密封组件，包括用于在涡轮机中密封牙齿的表面中的板材和凹槽部分
公开(公告)号：US20110285090A1
公开(公告)日：2011-11-24
申请号：US12782330
申请日：2010-05-18
申请人： Xiaoqing Zheng
发明人： Xiaoqing Zheng
IPC分类号： F01D11/02 , F16J15/44
CPC分类号： F01D11/001 , F01D5/225 , F01D11/02 , F01D11/025 , F01D11/16 , F05D2250/28 , F05D2250/29 , F05D2250/293
摘要： A seal assembly for sealing a stationary component and a rotating component including a seal tooth mating surface for mating with a seal tooth, the seal tooth mating surface including a plateau portion for sealingly receiving the seal tooth during a steady-state operation of the seal assembly and a first concave portion adjacent to the plateau portion for receiving the seal tooth with a clearance during a first non-steady-state operation of the seal assembly, wherein the seal tooth is coupled to one of the stationary component and the rotating component and the seal tooth mating surface is coupled to the other of the stationary component and the rotating component.
摘要翻译：一种用于密封固定部件的密封组件和包括用于与密封齿配合的密封齿配合表面的旋转部件，密封齿配合表面包括用于在密封组件的稳态操作期间密封地接收密封齿的平台部分以及与所述平台部分相邻的第一凹部，用于在所述密封组件的第一非稳态操作期间以间隙接收所述密封齿，其中所述密封齿与所述固定部件和所述旋转部件中的一个连接，密封齿配合表面联接到固定部件和旋转部件中的另一个。

25. 发明授权

US07967297B2 Thermally-activated control gap brush seal 有权
标题翻译：热敏控制间隙刷密封
公开(公告)号：US07967297B2
公开(公告)日：2011-06-28
申请号：US11685527
申请日：2007-03-13
申请人： Xiaoqing Zheng , Charles A. Trabert , Anthony G. O'Meara , Joshua J. Duquette
发明人： Xiaoqing Zheng , Charles A. Trabert , Anthony G. O'Meara , Joshua J. Duquette
IPC分类号： F16J15/44
CPC分类号： F16J15/3288 , F16J15/164 , Y10T29/53439
摘要： A brush seal for use with a housing and sealing a high pressure area from a low pressure area is provided. In an embodiment, the brush seal includes a retainer and a plurality of bristles. The retainer is comprised of a thermally-sensitive material having a thermal expansion rate. The bristles are connected to and extend from the retainer. In an embodiment, the retainer is not fixedly connected to the housing, and the thermal expansion rate of the retainer is greater than the thermal expansion rate of a portion of the housing adjacent the retainer. In another embodiment, a joint associated with a plurality of bristles is permitted to move into a headspace provided above the joint. A method for making a control-gap brush seal assembly for use in connection with a shaft is also disclosed.
摘要翻译：提供了一种用于壳体并从低压区域密封高压区域的刷密封。在一个实施例中，刷子密封件包括保持器和多个刷毛。保持器由具有热膨胀率的热敏材料构成。刷毛连接到保持器并从保持器延伸。在一个实施例中，保持器不固定地连接到壳体，并且保持器的热膨胀率大于邻近保持器的壳体的一部分的热膨胀率。在另一个实施例中，允许与多个刷毛相关联的关节移动到设置在关节上方的顶部空间中。还公开了一种制造用于与轴结合使用的控制间隙刷密封组件的方法。

26. 发明申请

US20110135445A1 PRESSURE BALANCED LOW-FRICTION SEAL 有权
标题翻译：压力平衡低摩擦密封
公开(公告)号：US20110135445A1
公开(公告)日：2011-06-09
申请号：US12630886
申请日：2009-12-04
申请人： Norman Arnold Turnquist , Keith Michael Parker , Xiaoqing Zheng , Rodrigo Rodriguez Erdmenger , Robbert Christiaan Pannekeet , Alexander Kimberley Simpson , Biao Fang
发明人： Norman Arnold Turnquist , Keith Michael Parker , Xiaoqing Zheng , Rodrigo Rodriguez Erdmenger , Robbert Christiaan Pannekeet , Alexander Kimberley Simpson , Biao Fang
IPC分类号： F01D11/00 , F16J15/16 , F16J9/00
CPC分类号： F16J9/20 , F05B2220/301 , F16J15/324
摘要： A pressure balance seal includes a sealing surface facing an inward radial direction, and a stator interface comprising at least one surface interfacing with a stator. The pressure balance seal further includes a friction reducing feature. The friction reducing feature includes a cavity on the sealing surface. The cavity is configured to receive a fluid such that a normal force acting on the pressure balance seal is counterbalanced by a force generated by a pressure of the fluid.
摘要翻译：压力平衡密封件包括面向内径向的密封表面，以及包括与定子相连接的至少一个表面的定子界面。压力平衡密封件还包括摩擦减小特征。摩擦减小特征包括在密封表面上的空腔。空腔构造成接收流体，使得作用在压力平衡密封件上的法向力由流体的压力产生的力抵消。

27. 发明授权

US07938403B1 Brush seals 有权
标题翻译：刷子密封
公开(公告)号：US07938403B1
公开(公告)日：2011-05-10
申请号：US12650896
申请日：2009-12-31
申请人： Vishwas K. Pandey , Bernard A. Couture, Jr. , William E. Adis , Michael D. Mack , Xiaoqing Zheng , Hemant V. Gedam
发明人： Vishwas K. Pandey , Bernard A. Couture, Jr. , William E. Adis , Michael D. Mack , Xiaoqing Zheng , Hemant V. Gedam
IPC分类号： F16J15/44
CPC分类号： F16J15/3288
摘要： A circumferentially extending brush seal positioned between static and rotary components of a machine and, during operation of the machine, the brush seal having a higher pressure region at an upstream side and a lower pressure region at a downstream side. The brush seal may include a plurality of bristles forming a bristle pack carried by the static component and cantilevered toward the rotary component such that tips of at least some of the bristles engage the rotary component. The brush seal further may include a pressure plate and a bristle pack backing plate. The bristle backing plate may include a plurality of radially extending and circumferentially spaced slots opening through opposite sides thereof. The slots may be disposed on an inner radial edge and an outer radial edge of the bristle backing plate.
摘要翻译：位于机器的静态和旋转部件之间的周向延伸的刷子密封件，并且在机器的操作期间，刷子密封件在上游侧具有较高的压力区域，在下游侧具有较低压力区域。刷密封可以包括多个刷毛，其形成由静态部件承载并且朝向旋转部件悬臂的刷毛包，使得至少一些刷毛的尖端接合旋转部件。刷密封件还可以包括压板和刷毛背衬板。刷毛背板可以包括通过其相对侧开口的多个径向延伸和周向隔开的槽。槽可以设置在刷毛背衬板的内径向边缘和外径向边缘上。

28. 发明申请

US20100164177A1 HYBRID MULTISTAGE BRUSH SEAL 审中-公开
标题翻译：混合多功能刷子密封
公开(公告)号：US20100164177A1
公开(公告)日：2010-07-01
申请号：US12345881
申请日：2008-12-30
申请人： Xiaoqing Zheng , Joshua J. Duquette
发明人： Xiaoqing Zheng , Joshua J. Duquette
IPC分类号： F16J15/44
CPC分类号： F16J15/006 , F05B2240/40 , F05B2240/571 , F16J15/3288
摘要： A multi-stage brush seal and assembly for sealing a circumferential gap with respect to a sealed component is disclosed. The brush seal includes a first stage including a first plurality of bristles and a second stage including a second plurality of bristles. In an embodiment, the first stage is configured with an initial first-stage clearance and seals said sealed component at high pressure and low pressure conditions, and the second stage is configured to have an initial second-stage clearance greater than the initial first-stage clearance so that the second stage does not seal said sealed component at the low pressure condition but is configured to be activated by a blow-down effect to seal said sealed component at the high pressure condition. In embodiments the brush seal includes features to enhance or reduce pressure blow-down with respect to the first-stage clearance.
摘要翻译：公开了一种用于密封相对于密封部件的周向间隙的多级刷密封和组件。毛刷密封件包括包括第一多个刷毛的第一阶段和包括第二多个刷毛的第二阶段。在一个实施例中，第一阶段配置有初始的第一级间隙，并在高压和低压条件下密封所述密封部件，并且第二级被配置为具有大于初始第一级的初始第二级间隙使得第二阶段不在所述低压条件下密封所述密封部件，而是构造成通过吹扫效应来激活以在高压条件下密封所述密封部件。在实施例中，刷子密封件包括用于增强或减小相对于第一级间隙的压力下降的特征。

29. 发明申请

US20080042364A1 MAGNETICALLY-CONTROLLED ROTARY SEAL 失效
标题翻译：磁控旋转密封
公开(公告)号：US20080042364A1
公开(公告)日：2008-02-21
申请号：US11775280
申请日：2007-07-10
申请人： Xiaoqing Zheng , Gerard M. Berard
发明人： Xiaoqing Zheng , Gerard M. Berard
IPC分类号： F16J15/34
CPC分类号： F16J15/3444
摘要： A non-contacting rotary face seal assembly includes a first sealing member, including a first sealing face and a first magnetic element; and a second sealing member, including a second sealing face and a second magnetic element. The first and second magnetic elements of the first and second sealing members provide a magnetic repulsion force between the first and second magnetic elements such that the magnetic repulsion force separates the first and second sealing faces before hydrodynamic or hydrostatic forces associated with rotation of the second sealing member become sufficient to prevent the first and second sealing faces from contacting.
摘要翻译：非接触式旋转面密封组件包括第一密封构件，包括第一密封面和第一磁性元件; 以及包括第二密封面和第二磁性元件的第二密封构件。第一和第二密封构件的第一和第二磁性元件在第一和第二磁性元件之间提供磁性排斥力，使得磁性排斥力在与第二密封件的旋转相关联的流体动力学或静水力之前分离第一和第二密封面构件变得足以防止第一和第二密封面接触。

30. 发明授权

US08794918B2 System for adjusting brush seal segments in turbomachine 有权
标题翻译：用于调整涡轮机中的刷密封段的系统
公开(公告)号：US08794918B2
公开(公告)日：2014-08-05
申请号：US12987052
申请日：2011-01-07
申请人： Sulficker Ali , Saravana Bhava Timmareddy , Seshu Kumar Mahankali , Xiaoqing Zheng
发明人： Sulficker Ali , Saravana Bhava Timmareddy , Seshu Kumar Mahankali , Xiaoqing Zheng
IPC分类号： F04D29/10
CPC分类号： F01D11/08 , F01D11/22 , F05D2240/56 , F16J15/164 , F16J15/3288
摘要： A system includes a brush seal segment. The brush seal segment includes a movable support including a head, an extension, and a seal surface, wherein the head is configured to mount in a chamber. The brush seal segment also includes a brush coupled to the movable support along the seal surface, wherein the seal surface consists essentially of the brush. The brush seal segment also includes a biasing element coupled to the movable support, wherein the biasing element is configured to bias the movable support from a first position to a second position to increase a brush clearance in a space between the brush and a rotor, and the movable support is configured to move from the second position to the first position to decrease the brush clearance in response to a fluid flow from the space to the chamber.
摘要翻译：系统包括刷密封段。刷子密封段包括可移动的支撑件，其包括头部，延伸部和密封表面，其中头部构造成安装在腔室中。刷密封段还包括沿着密封表面联接到可移动支撑件的刷子，其中密封表面基本上由刷子组成。刷密封段还包括联接到可移动支撑件的偏置元件，其中偏置元件构造成将可移动支撑件从第一位置偏置到第二位置，以增加刷子和转子之间的空间中的刷子间隙，以及可移动支撑件构造成响应于从空间到腔室的流体流动而从第二位置移动到第一位置以减小刷子间隙。

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