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    • 25. 发明申请
    • Headset recharger for cranially implantable medical devices
    • 用于头部可植入医疗器械的耳机充电器
    • US20050004619A1
    • 2005-01-06
    • US10835548
    • 2004-04-29
    • Carl WahlstrandWilliam PhillipsRobert Skime
    • Carl WahlstrandWilliam PhillipsRobert Skime
    • A61B5/00A61N1/08A61N1/32A61N1/378
    • A61N1/3787
    • The invention is directed to a recharging system and associated techniques to recharge an implantable medical device (IMD). In particular, a recharging system according to the invention comprises a headset having an energy delivery module that delivers energy to a power source of an IMD implanted on or within the cranium of a patient. The energy delivery module may comprise a coil for inductive transfer of energy to the power source. The headset may be configured for placement over the head of the patient, and may further only partially cover the top of the head. The energy delivery module may be adjustably coupled to the headset. In some embodiments, the position of the energy delivery module may be adjusted along three or four axes, including a rotational axis, allowing the coil to be placed over an IMD located at any of a variety of locations on or within the cranium.
    • 本发明涉及一种再充电系统和相关技术以对可植入医疗装置(IMD)进行再充电。 特别地,根据本发明的再充电系统包括具有能量递送模块的头戴式耳机,所述能量递送模块将能量传递到植入在患者的颅骨上或内部的IMD的动力源。 能量传递模块可以包括用于将能量感应地传递到电源的线圈。 耳机可以被配置为放置在患者的头部上,并且还可以仅部分地覆盖头部的顶部。 能量传递模块可以可调整地耦合到耳机。 在一些实施例中,能量输送模块的位置可以沿着三个或四个轴线(包括旋转轴线)进行调整,允许线圈放置在位于颅骨上或颅内的各种位置中的任何位置上的IMD上。
    • 26. 发明授权
    • Labeled cells for use in imaging
    • 用于成像的标记细胞
    • US4935223A
    • 1990-06-19
    • US229069
    • 1988-08-04
    • William Phillips
    • William Phillips
    • A61K51/12
    • A61K51/1203A61K2123/00
    • A process is provided for the labeling of viable eucaryotic cells. The process includes the steps of collecting, separating, and introducing a quantity of first type cells into a non-toxic media suitable to conduct an electric field. A labeling material is added to this media. The media containing the first type cells and the labeling material is pulsed for a period of time with an electric field, sufficient to render the cell membranes permeable so that the labeling material permeates the cells and becomes trapped therein upon cessation of the pulsing to produce labeled cells. Also provided is a process for diagnostically imaging pathological sites in a patient. This process contains the additional steps of administering the labeled cells to a patient and monitoring the localization of the labeling material in the patient to image the locus of a specific pathosis.
    • 提供了用于标记活的真核细胞的方法。 该方法包括以下步骤:将一定数量的第一类型细胞收集,分离和引入适合于进行电场的无毒介质中。 标签材料添加到此介质中。 含有第一类型细胞和标记材料的培养基用电场脉冲一段时间,足以使细胞膜渗透,使得标记材料在细胞停止时渗透到细胞中并被捕获,以产生标记的 细胞。 还提供了用于诊断性地成像患者中的病理部位的过程。 该过程包括将标记的细胞施用于患者并监测患者中标记物质的定位以对特定病变的位点进行成像的附加步骤。