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21. 发明申请

US20130073036A1 Cardiac Valve Procedure Methods and Devices 有权
标题翻译：心脏瓣膜手术方法和装置
公开(公告)号：US20130073036A1
公开(公告)日：2013-03-21
申请号：US13617989
申请日：2012-09-14
申请人： Gregory H. LAMBRECHT , John Liddicoat , Robert Kevin Moore
发明人： Gregory H. LAMBRECHT , John Liddicoat , Robert Kevin Moore
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2220/0016 , A61F2250/0059
摘要： A method of treating a diseased cardiac valve can include implanting a valve prosthesis by compressing the valve prosthesis to a compressed state for delivery and expanding the valve prosthesis to an expanded state for deployment. The valve prosthesis can include a valve fixation device having a plurality of struts, a first circumferential row of cells coupled to the struts, and a second circumferential row of cells coupled to the struts. The struts are substantially rigid such that the struts do not change dimensions between the compressed state and the expanded state. The valve prosthesis can also include a plurality of leaflets and a plurality of commissures. The valve is coupled to the valve fixation device such that the commissures are radially aligned with respective struts of the plurality of struts.
摘要翻译：治疗患病心脏瓣膜的方法可以包括通过将瓣膜假体压缩到压缩状态来植入瓣膜假体，用于输送和将瓣膜假体膨胀到展开状态以进行展开。瓣膜假体可以包括具有多个支柱的瓣膜固定装置，联接到支柱的第一圆周排的细胞以及耦合到支柱的第二圆周排细胞。支柱基本上是刚性的，使得支柱不会在压缩状态和膨胀状态之间改变尺寸。瓣膜假体还可以包括多个小叶和多个连合。阀联接到阀固定装置，使得连合件与多个支柱的相应支柱径向对准。

22. 发明授权

US07470284B2 Cardiac valve procedure methods and devices 有权
标题翻译：心脏瓣膜手术方法和装置
公开(公告)号：US07470284B2
公开(公告)日：2008-12-30
申请号：US10787057
申请日：2004-02-25
申请人： Gregory H. Lambrecht , John Liddicoat , Robert Kevin Moore
发明人： Gregory H. Lambrecht , John Liddicoat , Robert Kevin Moore
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2220/0016 , A61F2250/0059
摘要： The present invention discloses devices and methods for performing intravascular procedures with out cardiac bypass. The devices include various embodiments of temporary filter devices, temporary valves, and prosthetic valves. The temporary filter devices have one or more cannulae which provide access for surgical tools for effecting repair of the cardiac valves. A cannula may have filters of various configurations encircling the distal region of the cannula, which prevent embolitic material from entering the coronary arteries and aorta.The temporary valve devices may also have one or more cannulae which guide the insertion of the valve into the aorta. The valve devices expand in the aorta to occupy the entire flow path of the vessel. In one embodiment, the temporary valve is a disc of flexible, porous, material that acts to filter blood passing therethrough. A set of valve leaflets extend peripherally from the disc. [These leaflets can alternately collapse to prevent blood flow through the valve and extend to permit flow.The prosthetic valves include valve fixation devices which secure the prosthetic valve to the wall of the vessel. In one embodiment, the prosthetic valves have at least one substantially rigid strut, at least two expandable fixation rings located about the circumference of the base of the apex of the valve, and one or more commissures and leaflets. The prosthetic valves are introduced into the vascular system a compressed state, advanced to the site of implantation, expanded and secured to the vessel wall.]
摘要翻译：本发明公开了用心脏旁路进行血管内手术的装置和方法。这些装置包括临时过滤装置，临时阀和假肢阀的各种实施例。临时过滤器装置具有一个或多个套管，其提供用于外科手术工具的进入以实现心脏瓣膜的修复。套管可以具有围绕套管的远侧区域的各种构造的过滤器，其防止栓塞材料进入冠状动脉和主动脉。临时阀装置还可以具有一个或多个引导阀插入主动脉的套管。瓣膜装置在主动脉中扩张以占据血管的整个流动路径。在一个实施例中，临时阀是柔性多孔材料的盘，其用于过滤血液中的血液。一组瓣叶从圆盘外围延伸。

23. 发明申请

US20080065206A1 Fixation band for affixing a prosthetic heart valve to tissue 有权
标题翻译：用于将假心脏瓣膜固定到组织的固定带
公开(公告)号：US20080065206A1
公开(公告)日：2008-03-13
申请号：US11977702
申请日：2007-10-24
申请人： John Liddicoat
发明人： John Liddicoat
IPC分类号： A61F2/24 , A61F2/06
CPC分类号： A61F2/2409 , A61F2/2418 , A61F2220/0016 , A61F2250/0069
摘要： A fixation band has a tubular frame and a tube, wherein the tubular frame comprises longitudinally-extending members having a hook on its distal end and fixation means on its proximal end. The tubular frame preferably comprises a laterally-extending member for stabilization. The tube is positioned inside longitudinally-extending members and a sewing cuff is formed in the tube distal to the distalmost end of the longitudinally-extending members. A standard prosthetic valve can be secured to the fixation band by suturing the prosthetic valve's sewing cuff to the fixation band's sewing cuff and the prosthetic valve can be advanced to a valve seat. By pulling the tubular frame proximally, the hooks pass into surrounding tissue so that the fixation band and prosthetic valve are fixed against proximal movement. The fixation means then secure the fixation band to the surrounding tissue so that the prosthetic valve is fixed against distal movement.
摘要翻译：固定带具有管状框架和管，其中管状框架包括在其远端具有钩的纵向延伸构件和其近端上的固定装置。管状框架优选地包括用于稳定的横向延伸构件。该管位于纵向延伸的构件内部，并且在远离纵向延伸构件的最远端的管中形成缝合箍。通过将假肢瓣的缝合缝合到固定带的缝合箍上，可以将标准假肢瓣固定到固定带，并且可以将假体瓣推进到阀座。通过向近侧拉动管状框架，钩子进入周围组织，使得固定带和假肢瓣固定成近端运动。固定装置然后将固定带固定到周围组织，使得假肢瓣固定以防止远端运动。

24. 发明授权

US08591574B2 Cardiac valve procedure methods and devices 有权
标题翻译：心脏瓣膜手术方法和装置
公开(公告)号：US08591574B2
公开(公告)日：2013-11-26
申请号：US13220179
申请日：2011-08-29
申请人： Gregory H. Lambrecht , John Liddicoat , Robert Kevin Moore
发明人： Gregory H. Lambrecht , John Liddicoat , Robert Kevin Moore
IPC分类号： A61F2/24 , A61M29/00
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2220/0016 , A61F2250/0059
摘要： A method of performing an endovascular procedure within a patient can include inserting a filter into the patient's vascular system to restrict the passage of emboli through the filter while allowing blood to flow through the filter. The method can also include inserting a prosthetic valve into the patient's vascular system in a compressed state, and advancing the prosthetic valve to a site of implantation upstream of the filter. Additionally, the method includes implanting the prosthetic valve at the site of implantation by expanding at least a portion of the prosthetic value, and removing the filter from the patient's vascular system.
摘要翻译：在患者体内执行血管内手术的方法可以包括将过滤器插入患者的血管系统中以限制栓塞通过过滤器，同时允许血液流过过滤器。该方法还可以包括将假体瓣膜以压缩状态插入患者的血管系统中，并将人工瓣膜推进到过滤器上游的植入部位。另外，该方法包括通过扩展假体值的至少一部分并从患者的血管系统移除过滤器来将植入瓣膜植入植入位置。

25. 发明申请

US20070156167A1 Pressure attenuation device 有权
标题翻译：压力衰减装置
公开(公告)号：US20070156167A1
公开(公告)日：2007-07-05
申请号：US11527333
申请日：2006-09-26
申请人： Kevin Connors , John Liddicoat
发明人： Kevin Connors , John Liddicoat
IPC分类号： A61F2/06 , A61M29/00 , A61B19/00
CPC分类号： A61F2/06 , A61B2017/00243 , A61F2/0063 , A61F2/07 , A61F2/89 , A61F2/90 , A61F2/95 , A61F2002/068 , A61F2220/005 , A61F2220/0058 , A61F2250/0013
摘要： An implantable blood pressure regulator is provided. The blood pressure regulator includes at least one connection zone and an attenuation zone. The connection zone is suitable for connection to a body conduit, such as a blood vessel. The attenuation zone is movable from a first state to a second state in response to a physiological pressure spikes. The movement from the first state to the second state lowers a level of pressure or dampens a pressure spike in the body conduit.
摘要翻译：提供可植入的血压调节器。血压调节器包括至少一个连接区和衰减区。连接区域适于连接到身体导管，例如血管。响应于生理压力尖峰，衰减区可以从第一状态移动到第二状态。从第一状态到第二状态的运动降低了压力水平或抑制身体导管中的压力尖峰。

26. 发明申请

US20050261759A1 Cardiac valve procedure methods and devices 审中-公开
公开(公告)号：US20050261759A1
公开(公告)日：2005-11-24
申请号：US11115064
申请日：2005-04-26
申请人： Gregory Lambrecht , John Liddicoat , Robert Moore
发明人： Gregory Lambrecht , John Liddicoat , Robert Moore
IPC分类号： A61F2/06 , A61F2/24 , A61M5/00
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2220/0016 , A61F2250/0059
摘要： The present invention discloses devices and methods for performing intravascular procedures with out cardiac bypass. The devices include various embodiments of temporary filter devices, temporary valves, and prosthetic valves. The temporary filter devices have one or more cannulae which provide access for surgical tools for effecting repair of the cardiac valves. A cannula may have filters of various configurations encircling the distal region of the cannula, which prevent embolitic material from entering the coronary arteries and aorta. The temporary valve devices may also have one or more cannulae which guide the insertion of the valve into the aorta. The valve devices expand in the aorta to occupy the entire flow path of the vessel. In one embodiment, the temporary valve is a disc of flexible, porous, material that acts to filter blood passing therethrough. A set of valve leaflets extend peripherally from the disc. These leaflets can alternately collapse to prevent blood flow through the valve and extend to permit flow. The prosthetic valves include valve fixation devices which secure the prosthetic valve to the wall of the vessel. In one embodiment, the prosthetic valves have at least one substantially rigid strut, at least two expandable fixation rings located about the circumference of the base of the apex of the valve, and one or more commissures and leaflets. The prosthetic valves are introduced into the vascular system a compressed state, advanced to the site of implantation, expanded and secured to the vessel wall.

27. 发明授权

US06896690B1 Cardiac valve procedure methods and devices 有权
标题翻译：心脏瓣膜手术方法和装置
公开(公告)号：US06896690B1
公开(公告)日：2005-05-24
申请号：US09700167
申请日：2000-01-27
申请人： Gregory H. Lambrecht , John Liddicoat , Robert Kevin Moore
发明人： Gregory H. Lambrecht , John Liddicoat , Robert Kevin Moore
IPC分类号： A61F2/06 , A61F2/24 , A61M5/00
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2220/0016 , A61F2250/0059
摘要： The present invention discloses devices and methods for performing intravascular procedures with out cardiac bypass. The devices include various embodiments of temporary filter devices, temporary valves, and prosthetic valves.The temporary filter devices have one or more cannulae which provide access for surgical tools for effecting repair of the cardiac valves. A cannula may have filters of various configurations encircling the distal region of the cannula, which prevent embolitic material from entering the coronary arteries and aorta.The temporary valve devices may also have one or more cannulae which guide the insertion of the valve into the aorta. The valve devices expand in the aorta to occupy the entire flow path of the vessel. In one embodiment, the temporary valve is a disc of flexible, porous, material that acts to filter blood passing therethrough. A set of valve leaflets extend peripherally from the disc. These leaflets can alternately collapse to prevent blood flow through the valve and extend to permit flow.The prosthetic valves include valve fixation devices which secure the prosthetic valve to the wall of the vessel. In one embodiment, the prosthetic valves have at least one substantially rigid strut, at least two expandable fixation rings located about the circumference of the base of the apex of the valve, and one or more commissures and leaflets. The prosthetic valves are introduced into the vascular system a compressed state, advanced to the site of implantation, expanded and secured to the vessel wall.
摘要翻译：本发明公开了用心脏旁路进行血管内手术的装置和方法。这些装置包括临时过滤装置，临时阀和假肢阀的各种实施例。临时过滤器装置具有一个或多个套管，其提供用于外科手术工具的进入以实现心脏瓣膜的修复。套管可以具有围绕套管的远侧区域的各种构造的过滤器，其防止栓塞材料进入冠状动脉和主动脉。临时阀装置还可以具有一个或多个引导阀插入主动脉的套管。瓣膜装置在主动脉中扩张以占据血管的整个流动路径。在一个实施例中，临时阀是柔性多孔材料的盘，其用于过滤血液中的血液。一组瓣叶从圆盘外围延伸。这些传单可以交替塌缩，以防止血液流过阀门并延伸以允许流动。假体瓣膜包括固定假体瓣膜至血管壁的瓣膜固定装置。在一个实施例中，人造瓣膜具有至少一个基本上刚性的支柱，围绕阀的顶点的基部的圆周定位的至少两个可扩张的固定环，以及一个或多个连合和传单。人造瓣膜被引入血管系统中的压缩状态，前进到植入部位，扩张并固定到血管壁。

28. 发明授权

US08740974B2 Cardiac valve procedure methods and devices 有权
标题翻译：心脏瓣膜手术方法和装置
公开(公告)号：US08740974B2
公开(公告)日：2014-06-03
申请号：US13617989
申请日：2012-09-14
申请人： Gregory H. Lambrecht , John Liddicoat , Robert Kevin Moore
发明人： Gregory H. Lambrecht , John Liddicoat , Robert Kevin Moore
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2220/0016 , A61F2250/0059
摘要： A method of treating a diseased cardiac valve can include implanting a valve prosthesis by compressing the valve prosthesis to a compressed state for delivery and expanding the valve prosthesis to an expanded state for deployment. The valve prosthesis can include a valve fixation device having a plurality of struts, a first circumferential row of cells coupled to the struts, and a second circumferential row of cells coupled to the struts. The struts are substantially rigid such that the struts do not change dimensions between the compressed state and the expanded state. The valve prosthesis can also include a plurality of leaflets and a plurality of commissures. The valve is coupled to the valve fixation device such that the commissures are radially aligned with respective struts of the plurality of struts.
摘要翻译：治疗患病心脏瓣膜的方法可以包括通过将瓣膜假体压缩到压缩状态来植入瓣膜假体，用于输送和将瓣膜假体膨胀到展开状态以进行展开。瓣膜假体可以包括具有多个支柱的瓣膜固定装置，耦合到支柱的第一圆周排的细胞以及耦合到支柱的第二圆周排细胞。支柱基本上是刚性的，使得支柱不会在压缩状态和膨胀状态之间改变尺寸。瓣膜假体还可以包括多个小叶和多个连合。阀联接到阀固定装置，使得连合件与多个支柱的相应支柱径向对准。

29. 发明申请

US20110313446A1 Cardiac Valve Procedure Methods and Devices 有权
标题翻译：心脏瓣膜手术方法和装置
公开(公告)号：US20110313446A1
公开(公告)日：2011-12-22
申请号：US13220179
申请日：2011-08-29
申请人： Gregory H. LAMBRECHT , John Liddicoat , Robert Kevin Moore
发明人： Gregory H. LAMBRECHT , John Liddicoat , Robert Kevin Moore
IPC分类号： A61F2/01
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2220/0016 , A61F2250/0059
摘要： A method of performing an endovascular procedure within a patient can include inserting a filter into the patient's vascular system to restrict the passage of emboli through the filter while allowing blood to flow through the filter. The method can also include inserting a prosthetic valve into the patient's vascular system in a compressed state, and advancing the prosthetic valve to a site of implantation upstream of the filter. Additionally, the method includes implanting the prosthetic valve at the site of implantation by expanding at least a portion of the prosthetic valve, and removing the filter from the patient's vascular system.
摘要翻译：在患者体内执行血管内手术的方法可以包括将过滤器插入患者的血管系统中以限制栓塞通过过滤器，同时允许血液流过过滤器。该方法还可以包括将假体瓣膜以压缩状态插入患者的血管系统中，并将人工瓣膜推进到过滤器上游的植入部位。另外，该方法包括通过使至少一部分人工瓣膜膨胀并从患者血管系统中移除过滤器将植入假体瓣膜植入植入位置。

30. 发明申请

US20060020336A1 Automated annular plication for mitral valve repair 审中-公开
标题翻译：二尖瓣修复的自动环形瓣
公开(公告)号：US20060020336A1
公开(公告)日：2006-01-26
申请号：US11056553
申请日：2005-02-11
申请人： John Liddicoat
发明人： John Liddicoat
IPC分类号： A61F2/24
CPC分类号： A61F2/2487 , A61B17/0644 , A61B17/0684 , A61B2017/00243 , A61B2017/0641 , A61F2/2445 , A61F2/2451
摘要： A method for reducing mitral regurgitation comprising: providing a plication assembly comprising a first anchoring element, a second anchoring element, and a linkage construct connecting the first anchoring element to the second anchoring element; positioning the first anchoring element in the coronary sinus adjacent to the mitral annulus, and positioning the second anchoring element in another area of the mitral annulus so that the linkage construct extends across the opening of the mitral valve and holds the mitral valve in a reconfigured configuration so as to reduce mitral regurgitation. An apparatus for reducing mitral regurgitation comprising: a plication assembly comprising a first anchoring element, a second anchoring element, and a linkage construct connecting the first anchoring element to the second anchoring element; and a catheter adapted to deliver the first anchoring element to the coronary sinus.
摘要翻译：一种减少二尖瓣反流的方法，包括：提供包括第一锚固元件，第二锚定元件和将第一锚固元件连接到第二锚定元件的连接结构的折叠组件; 将第一锚定元件定位在与二尖瓣环相邻的冠状窦中，并将第二锚定元件定位在二尖瓣环的另一区域中，使得连杆结构延伸穿过二尖瓣的开口并将二尖瓣保持在重新构型中以减少二尖瓣反流。一种用于减少二尖瓣反流的装置，包括：折叠组件，包括第一锚固元件，第二锚定元件和将第一锚定元件连接到第二锚定元件的连接结构; 以及适于将第一锚定元件递送到冠状窦的导管。

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