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21. 发明申请

US20050152690A1 Production method of silver halide photographic emulsion and production apparatus thereof 失效
标题翻译：卤化银摄影乳液的制备方法及其制备装置
公开(公告)号：US20050152690A1
公开(公告)日：2005-07-14
申请号：US10995121
申请日：2004-11-24
申请人： Hideharu Nagasawa , Yasunori Ichikawa , Fumiko Shiraishi , Hiroshi Maeda , Mamoru Fujisawa
发明人： Hideharu Nagasawa , Yasunori Ichikawa , Fumiko Shiraishi , Hiroshi Maeda , Mamoru Fujisawa
IPC分类号： B01F5/04 , B01F11/02 , B01F13/00 , B01F15/06 , B01J19/00 , G03C1/015 , G03B13/20
CPC分类号： B01F13/0062 , B01F5/0453 , B01F5/046 , B01F11/0266 , B01F13/0001 , B01F13/0066 , B01F13/0067 , B01F15/067 , B01F2215/0454 , B01J19/0093 , B01J2219/00783 , B01J2219/00822 , B01J2219/00833 , B01J2219/00869 , B01J2219/00873 , B01J2219/00889 , G03C1/015 , G03C1/08 , G03C2200/09 , G03C2200/58
摘要： At least one of a nucleus forming process, a nucleus growing process, a chemical sensitizing process, and a spectral sensitizing process for producing a silver halide photographic emulsion is performed by using a microreactor. A minute region of the microreactor is used to precisely perform a reaction of nucleus formation. A condition under which host grains are allowed to react with newly supplied silver halide nuclei is made uniform to cause uniform crystal growth. A predetermined quantity of molecules for chemical sensitization is doped in a crystal lattice of a nucleus of silver halide to effect a sensitizing process. Alternatively, a spectral sensitizing process in which a single molecular layer of a spectral sensitizer is uniformly adsorbed on a silver halide nucleus grain surface is securely carried out.
摘要翻译：使用微反应器进行核生成过程，核生长过程，化学增感过程和用于制备卤化银照相乳剂的光谱增感方法中的至少一种。微反应器的微小区域用于精确地进行核形成反应。使主体颗粒与新提供的卤化银核反应的条件被均匀化以引起均匀的晶体生长。预定量的用于化学增感的分子被掺杂在卤化银核的晶格中以实现敏化过程。或者，可靠地进行光谱增感剂的单分子层均匀地吸附在卤化银核粒子表面上的光谱增感过程。

22. 发明授权

US07171974B2 Production method of silver halide photographic emulsion and production apparatus thereof 失效
标题翻译：卤化银摄影乳液的制备方法及其制备装置
公开(公告)号：US07171974B2
公开(公告)日：2007-02-06
申请号：US10995121
申请日：2004-11-24
申请人： Hideharu Nagasawa , Yasunori Ichikawa , Fumiko Shiraishi , Hiroshi Maeda , Mamoru Fujisawa
发明人： Hideharu Nagasawa , Yasunori Ichikawa , Fumiko Shiraishi , Hiroshi Maeda , Mamoru Fujisawa
IPC分类号： E03B1/00 , F17D1/00 , B01J10/00 , G03B13/00 , G03C1/005
CPC分类号： B01F13/0062 , B01F5/0453 , B01F5/046 , B01F11/0266 , B01F13/0001 , B01F13/0066 , B01F13/0067 , B01F15/067 , B01F2215/0454 , B01J19/0093 , B01J2219/00783 , B01J2219/00822 , B01J2219/00833 , B01J2219/00869 , B01J2219/00873 , B01J2219/00889 , G03C1/015 , G03C1/08 , G03C2200/09 , G03C2200/58
摘要： At least one of a nucleus forming process, a nucleus growing process, a chemical sensitizing process, and a spectral sensitizing process for producing a silver halide photographic emulsion is performed by using a microreactor. A minute region of the microreactor is used to precisely perform a reaction of nucleus formation. A condition under which host grains are allowed to react with newly supplied silver halide nuclei is made uniform to cause uniform crystal growth. A predetermined quantity of molecules for chemical sensitization is doped in a crystal lattice of a nucleus of silver halide to effect a sensitizing process. Alternatively, a spectral sensitizing process in which a single molecular layer of a spectral sensitizer is uniformly adsorbed on a silver halide nucleus grain surface is securely carried out.
摘要翻译：使用微反应器进行核生成过程，核生长过程，化学增感过程和用于制备卤化银照相乳剂的光谱增感方法中的至少一种。微反应器的微小区域用于精确地进行核形成反应。使主体颗粒与新提供的卤化银核反应的条件被均匀化以引起均匀的晶体生长。预定量的用于化学增感的分子被掺杂在卤化银核的晶格中以实现敏化过程。或者，可靠地进行光谱增感剂的单分子层均匀地吸附在卤化银核粒子表面上的光谱增感过程。

23. 发明授权

US07939034B2 Method and tool for collecting blood plasma 有权
标题翻译：收集血浆的方法和工具
公开(公告)号：US07939034B2
公开(公告)日：2011-05-10
申请号：US11905026
申请日：2007-09-27
申请人： Fumiko Shiraishi , Yasunori Ichikawa , Takayuki Fujiwara , Hideharu Nagasawa , Kazunori Takahashi
发明人： Fumiko Shiraishi , Yasunori Ichikawa , Takayuki Fujiwara , Hideharu Nagasawa , Kazunori Takahashi
IPC分类号： C12M1/12
CPC分类号： B01L3/502753 , B01L2300/0825 , B01L2400/086 , Y10T436/25375
摘要： According to a blood plasma collection tool of the present invention, a phenomenon that blood cells in blood spontaneously precipitate due to an effect of gravitational force takes place in the very narrow microspace (separation part) having the very narrow depth in the direction of gravitational force of not greater than 1 mm, and the overflow channel functions as a dam against the separation part so that the blood plasma separated out as supernatant fluid can overflow beyond the overflow channel, whereby the blood cells separated out can be prevented from entering the collection part. Therefore, blood plasma can be collected by accurately and readily separating blood plasma and blood cells in a small amount of blood from each other in a short time, using a small tool having a simple structure.
摘要翻译：根据本发明的血浆收集工具，由于重力的作用，血液中的血细胞自发沉淀的现象发生在在重力方向具有非常窄的深度的非常狭窄的微空间（分离部分）中不超过1mm，并且溢流通道用作对分离部分的阻挡物，使得作为上清液分离出的血浆可以溢出超过溢流通道，从而可以防止分离出的血细胞进入收集部分。因此，可以通过使用具有简单结构的小型工具，在短时间内准确且容易地将少量血液中的血浆和血细胞分离，从而收集血浆。

24. 发明申请

US20070074773A1 Fluidic device 审中-公开
标题翻译：流体装置
公开(公告)号：US20070074773A1
公开(公告)日：2007-04-05
申请号：US11540520
申请日：2006-10-02
申请人： Fumiko Shiraishi , Yasunori Ichikawa , Norihito Nosaka , Hideharu Nagasawa
发明人： Fumiko Shiraishi , Yasunori Ichikawa , Norihito Nosaka , Hideharu Nagasawa
IPC分类号： F15C1/04
CPC分类号： B01J19/0093 , B01J2219/00783 , B01J2219/00788 , B01J2219/00822 , B01J2219/00824 , B01J2219/00828 , B01J2219/00831 , B01J2219/00833 , B01J2219/0086 , B01J2219/00873 , B01J2219/00889 , F28D7/103 , F28D9/005 , F28D2021/0077 , F28F3/12 , F28F13/12 , F28F2260/02 , Y10T137/2196
摘要： A fluidic device, comprising: a temperature regulating mechanism for regulating a temperature of a plurality of fluids in a reaction operation or a unit operation while the fluids are distributed in a fluid flow path, wherein the temperature regulating mechanism includes a heating medium flow path formed therein along a flow direction of the fluids in the fluid flow path in which a heating medium at a desired temperature flows and a disturbance producing device for producing turbulence in a laminar flow of the heating medium.
摘要翻译：一种流体装置，包括：温度调节机构，用于在流体分布在流体流动路径中时在反应操作或单元操作中调节多个流体的温度，其中温度调节机构包括形成的加热介质流动路径其中在流体流动路径中流过所需温度的加热介质流动的流体的流动方向以及用于在加热介质的层流中产生湍流的扰动产生装置。

25. 发明授权

US07641890B2 Inorganic fine particle and method for producing the same using microchannel 有权
标题翻译：无机微粒及其制造方法，使用微通道
公开(公告)号：US07641890B2
公开(公告)日：2010-01-05
申请号：US11723258
申请日：2007-03-19
申请人： Hideharu Nagasawa , Yasunori Ichikawa
发明人： Hideharu Nagasawa , Yasunori Ichikawa
IPC分类号： B01F5/06
CPC分类号： C01G1/00 , B82Y30/00 , C01G23/053 , C01P2004/64 , Y10S423/09 , Y10T428/2982
摘要： The present invention provides a method for producing an inorganic fine particle comprising the step of: reacting two or more reaction solutions for forming an inorganic fine particle while the reaction solutions flow in a non-laminar flow state in a microchannel, thereby form the inorganic fine particle, and an inorganic fine particle produced by the production method. The method for producing an inorganic fine particle of the present invention can stably produce monodisperse inorganic fine particles of nanometer size and allows for flexible response to formulation conditions (e.g., varying flow rate ratios between reaction solutions to be mixed) and for high-throughput production.
摘要翻译：本发明提供了一种无机细粒的制造方法，其特征在于，包括以下工序：使两种以上的反应溶液反应，形成无机微粒，同时使反应液在微通道中以非层流状态流动，形成无机细颗粒和通过该制造方法制造的无机细颗粒。本发明的无机微粒的制造方法可以稳定地制造纳米尺寸的单分散无机细颗粒，并且允许对配制条件（例如，要混合的反应溶液之间的变化的流速比）和用于高产量生产的灵活响应。

26. 发明申请

US20090087683A1 Reaction Method and Apparatus and Method and Apparatus for Manufacturing Chemical Substance Using the Same 审中-公开
标题翻译：用于制造化学物质的反应方法和装置及其方法和装置
公开(公告)号：US20090087683A1
公开(公告)日：2009-04-02
申请号：US11910263
申请日：2006-03-28
申请人： Fumiko Shiraishi , Hideharu Nagasawa , Yasunori Ichikawa , Seiji Sugiyama , Koukichi Waki
发明人： Fumiko Shiraishi , Hideharu Nagasawa , Yasunori Ichikawa , Seiji Sugiyama , Koukichi Waki
IPC分类号： G11B5/00 , B01J14/00 , B01D19/00 , B01J19/10 , B01F3/08
CPC分类号： B01J19/1856 , B01D19/0042 , B01F5/0256 , B01F15/065 , B01F2015/062 , B01J4/002 , B01J10/00 , B01J14/00 , B01J19/0066 , B01J19/008 , B01J19/10 , B01J19/1806 , B01J19/1862 , B01J19/2405 , B01J19/26 , B01J2219/00094 , B82Y25/00 , G11B5/706 , G11B5/714 , H01F1/0054 , H01F1/065 , H01F10/007
摘要： The present invention provides a reaction method for a reaction system generating gas by a reaction, comprising the steps of: providing a sealed mixing section for mixing a plurality of liquids to start a reaction and a degassing section having a gas-liquid interface for removing, from a reaction liquid, gas bubbles generated from a mixed reaction liquid, separately; and feeding the reaction liquid mixed in the mixing section to the degassing section, without being interfered by gas bubbles even in a reaction system where gas is generated by a reaction, so that it is possible to stabilize a reaction at the start of the reaction and in the progress of the reaction and stably feed liquid to a subsequent process.
摘要翻译：本发明提供了通过反应产生气体的反应体系的反应方法，包括以下步骤：提供用于混合多种液体以开始反应的密封混合部分和具有气液界面的脱气部分，从反应液中分离出由混合反应液产生的气泡; 以及即使在通过反应产生气体的反应系统中也将混合部分中混合的反应液体进料到脱气部分，而不会被气泡干扰，从而可以稳定反应开始时的反应，在反应进程中并稳定地将液体进料到随后的过程中。

27. 发明申请

US20070292686A1 Inorganic fine particle and method for producing the same 有权
标题翻译：无机微粒及其制造方法
公开(公告)号：US20070292686A1
公开(公告)日：2007-12-20
申请号：US11723258
申请日：2007-03-19
申请人： Hideharu Nagasawa , Yasunori Ichikawa
发明人： Hideharu Nagasawa , Yasunori Ichikawa
IPC分类号： C01G23/047
CPC分类号： C01G1/00 , B82Y30/00 , C01G23/053 , C01P2004/64 , Y10S423/09 , Y10T428/2982
摘要： The present invention provides a method for producing an inorganic fine particle comprising the step of: reacting two or more reaction solutions for forming an inorganic fine particle while the reaction solutions flow in a non-laminar flow state in a microchannel, thereby form the inorganic fine particle, and an inorganic fine particle produced by the production method. The method for producing an inorganic fine particle of the present invention can stably produce monodisperse inorganic fine particles of nanometer size and allows for flexible response to formulation conditions (e.g., varying flow rate ratios between reaction solutions to be mixed) and for high-throughput production.
摘要翻译：本发明提供了一种无机细粒的制造方法，其特征在于，包括以下工序：使两种以上的反应溶液反应，形成无机微粒，同时使反应液在微通道中以非层流状态流动，形成无机细颗粒和通过该制造方法制造的无机细颗粒。本发明的无机微粒的制造方法可以稳定地制造纳米尺寸的单分散无机细颗粒，并且允许对配制条件（例如，要混合的反应溶液之间的变化的流速比）和用于高产量生产的灵活响应。

28. 发明授权

US06406821B1 Method for preparing silver halide emulsions and apparatus for implementing the method 失效
标题翻译：制备卤化银乳剂的方法及其实施方法
公开(公告)号：US06406821B1
公开(公告)日：2002-06-18
申请号：US09684834
申请日：2000-10-10
申请人： Yasunori Ichikawa , Hideharu Nagasawa , Tetsuo Nomiyama
发明人： Yasunori Ichikawa , Hideharu Nagasawa , Tetsuo Nomiyama
IPC分类号： G03C1015
CPC分类号： G03C1/015 , B01F3/0807 , B01F3/088 , B01F15/00357 , B01F15/0238 , B01F15/0261 , B01F15/0441 , B01F2013/1091 , B01F2215/0093
摘要： A method and an apparatus for precisely controlling flow rate of reactant solution such as silver nitrate solution or halide salt solution which is added into a precipitation vessel. The method comprises applying a pressure to each source of said two solutions and controlling both said applied pressure and a flow resistance of each feed lines of said two solutions so that each flow rate of the two solutions to be added into the precipitation vessel can be adjusted to a predetermined value. The apparatus comprises a storage vessel for the reactant, a feed line to feed the reactant into the precipitation vessel and a flow rate controller, wherein the storage vessel is connected to a pressure controller which includes a pressure vessel pressurized with air or other gases and a pressure control valve, the feed line has a pressure sensor for detecting a pressure inside the feed line, a flow meter and a flow path opening controller along its line in order, the flow rate controller controls the flow rate of the reactant fed into the precipitation vessel by controlling the pressure control valve and the flow path opening controller.
摘要翻译：一种精确控制反应物溶液如硝酸银溶液或卤化物盐溶液流入沉淀容器的方法和装置。所述方法包括对所述两种溶液的每个源施加压力并控制所述施加的压力和所述两种溶液的每个进料管的流动阻力，使得可以调节要添加到沉淀容器中的两种溶液的每个流速达到预定值。该装置包括用于反应物的储存容器，将反应物进料到沉淀容器中的进料管线和流量控制器，其中该储存容器连接到压力控制器，压力控制器包括用空气或其它气体加压的压力容器和压力控制阀，进料管线具有用于检测进料管线内的压力的压力传感器，流量计和流路开启控制器，其流量控制器控制进料到沉淀物中的反应物的流量通过控制压力控制阀和流路打开控制器的容器。

29. 发明授权

US06838232B2 Production method of silver halide photographic emulsion and production apparatus thereof 失效
公开(公告)号：US06838232B2
公开(公告)日：2005-01-04
申请号：US10345406
申请日：2003-01-16
申请人： Hideharu Nagasawa , Yasunori Ichikawa , Fumiko Shiraishi , Hiroshi Maeda , Mamoru Fujisawa
发明人： Hideharu Nagasawa , Yasunori Ichikawa , Fumiko Shiraishi , Hiroshi Maeda , Mamoru Fujisawa
IPC分类号： B01F5/04 , B01F11/02 , B01F13/00 , B01F15/06 , B01J19/00 , G03C1/015 , G03C5/18 , G03C5/26
CPC分类号： B01F13/0062 , B01F5/0453 , B01F5/046 , B01F11/0266 , B01F13/0001 , B01F13/0066 , B01F13/0067 , B01F15/067 , B01F2215/0454 , B01J19/0093 , B01J2219/00783 , B01J2219/00822 , B01J2219/00833 , B01J2219/00869 , B01J2219/00873 , B01J2219/00889 , G03C1/015 , G03C1/08 , G03C2200/09 , G03C2200/58
摘要： At least one of a nucleus forming process, a nucleus growing process, a chemical sensitizing process, and a spectral sensitizing process for producing a silver halide photographic emulsion is performed by using a microreactor. A minute region of the microreactor is used to precisely perform a reaction of nucleus formation. A condition under which host grains are allowed to react with newly supplied silver halide nuclei is made uniform to cause uniform crystal growth. A predetermined quantity of molecules for chemical sensitization is doped in a crystal lattice of a nucleus of silver halide to effect a sensitizing process. Alternatively, a spectral sensitizing process in which a single molecular layer of a spectral sensitizer is uniformly adsorbed on a silver halide nucleus grain surface is securely carried out.

30. 发明申请

US20080241956A1 METHOD FOR DETECTING ANALYTE AND BIOCHIP 审中-公开
标题翻译：检测分析和生物技术的方法
公开(公告)号：US20080241956A1
公开(公告)日：2008-10-02
申请号：US12058718
申请日：2008-03-30
申请人： Fumiko Hirai , Yasunori Ichikawa , Kazunori Takahashi
发明人： Fumiko Hirai , Yasunori Ichikawa , Kazunori Takahashi
IPC分类号： G01N1/28 , B01J19/00
CPC分类号： G01N1/4022 , G01N2001/4027 , Y10T436/25
摘要： A method for detecting an analyte in a sample liquid, using a detection reagent which reacts specifically with the analyte to give structural information on the analyte, comprising the steps of: a step of dropping the sample liquid containing the analyte onto a substrate and evaporating a solvent in the droplet by feeding a gas to the droplet; and a step of contacting the droplet with the detection reagent.
摘要翻译：一种检测样品液体中的分析物的方法，使用与分析物特异性反应以产生关于分析物的结构信息的检测试剂，包括以下步骤：将含有分析物的样品液体滴加到基底上并蒸发通过向液滴供给气体在液滴中的溶剂; 以及使液滴与检测试剂接触的步骤。

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